D-Pinitol prevents rat breast carcinogenesis induced by 7, 12 -Dimethylbenz [a] anthracene through inhibition of Bcl-2 and induction of p53, caspase-3 proteins and modulation of hepatic biotransformation enzymes and antioxidants

Biomedicine and Preventive Nutrition

Volumn 3, Issue 1, 2013, Pages 31-41

  Rengarajan, Thamaraiselvan ^a   Nandakumar, Natarajan ^a   Balasubramanian, Maruthaiveeran Periyasamy ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Antioxidants; Bcl 2; Caspase 3; D Pinitol; LPO; P53; RT PCR; Xenobiotic enzymes

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; ALPHA TOCOPHEROL; ANTINEOPLASTIC AGENT; ASCORBIC ACID; CASPASE 3; CATALASE; CYTOCHROME B5; CYTOCHROME P450; DEXTRO PINITOL; DRUG METABOLIZING ENZYME; GLUCURONOSYLTRANSFERASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; LIPID; LIVER ENZYME; MESSENGER RNA; NUCLEIC ACID; PROTEIN BCL 2; PROTEIN P53; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BIOTRANSFORMATION; BODY WEIGHT; BREAST; BREAST CANCER; BREAST CARCINOGENESIS; CANCER INHIBITION; CANCER PREVENTION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INDUCTION; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; LIPID PEROXIDATION; LIVER MICROSOME; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR VOLUME; UPREGULATION; WESTERN BLOTTING;

ANIMALIA; RATTUS;

EID: 84875268568     PISSN: 22105239     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bionut.2012.07.001     Document Type: Article

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