Gastrin acting on the cholecystokinin2 receptor induces cyclooxygenase-2 expression through JAK2/STAT3/PI3K/Akt pathway in human gastric cancer cells

Cancer Letters

Volumn 332, Issue 1, 2013, Pages 11-18

  Xu, Wei ^a   Chen, Guo Sheng ^a   Shao, Yun ^a   Li, Xiao Lin ^a   Xu, Hai Chen ^a   Zhang, Hao ^a   Zhu, Guo Qing ^a   Zhou, Yi Chan ^a   He, Xiao Pu ^a   Sun, Wei Hao ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Cholecystokinin2 receptor; Cyclooxygenase 2; Gastric cancer; JAK2 STAT3; PI3K Akt

Indexed keywords

1 [2,3 DIHYDRO 1 (2' METHYLPHENACYL) 2 OXO 5 PHENYL 1H 1,4 BENZODIAZEPIN 3 YL] 3 (3 METHYLPHENYL)UREA; CHOLECYSTOKININ B RECEPTOR; CHOLECYSTOKININ B RECEPTOR ANTAGONIST; CYCLOOXYGENASE 2; GASTRIN; GASTRIN 17; JANUS KINASE 2; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; STAT3 PROTEIN;

ARTICLE; CANCER CELL CULTURE; CELL PROLIFERATION; ENZYME ACTIVATION; GENE SILENCING; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; STOMACH CANCER; STOMACH CARCINOGENESIS; UPREGULATION;

CELL LINE, TUMOR; CELL PROLIFERATION; CYCLOOXYGENASE 2; GASTRINS; HUMANS; JANUS KINASE 2; PHOSPHATIDYLINOSITOL 3-KINASE; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, CHOLECYSTOKININ B; RNA INTERFERENCE; RNA, MESSENGER; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STOMACH NEOPLASMS; TIME FACTORS; TRANSFECTION; UP-REGULATION;

EID: 84875253067     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2012.12.030     Document Type: Article

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