The radial diffusivity and magnetization transfer pool size ratio are sensitive markers for demyelination in a rat model of type III multiple sclerosis (MS) lesions

NeuroImage

Volumn 74, Issue , 2013, Pages 298-305

  Janve, Vaibhav A ^a   Zu, Zhongliang ^a   Yao, Song Yi ^b   Li, Ke ^a   Zhang, Fang Lin ^b   Wilson, Kevin J ^a   Ou, Xiawei ^a   Does, Mark D ^a   Subramaniam, Sriram ^b   Gochberg, Daniel F ^a  

^a VANDERBILT UNIVERSITY   (United States)

^b VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

9.4T; Demyelination; Diffusion tensor imaging (DTI); Lippopolysaccharide (LPS); Multiple sclerosis (MS); Myelin; Quantitative magnetization transfer (qMT); Rat brain; White matter

Indexed keywords

MYELIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; DEMYELINATION; DIFFUSION TENSOR IMAGING; HISTOPATHOLOGY; IMAGE ANALYSIS; MULTIPLE SCLEROSIS; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POOL SIZE RATIO; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; QUANTITATIVE MAGNETIZATION TRANSFER; RADIAL DIFFUSIVITY; RADIOLOGICAL PARAMETERS; RAT; TYPE III MULTIPLE SCLEROSIS;

ANIMALS; ANISOTROPY; BRAIN; DEMYELINATING DISEASES; DIFFUSION TENSOR IMAGING; DISEASE MODELS, ANIMAL; IMAGE PROCESSING, COMPUTER-ASSISTED; MULTIPLE SCLEROSIS; RATS;

EID: 84875249130     PISSN: 10538119     EISSN: 10959572     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2013.02.034     Document Type: Article

References (38)

1. Basser P.J., Pierpaoli C. A simplified method to measure the diffusion tensor from seven MR images. Magn. Reson. Med. 1998, 39(6):928-934.
2. Beaulieu C. The basis of anisotropic water diffusion in the nervous system - a technical review. NMR Biomed. 2002, 15(7-8):435-455.
3. Berry I., Barker G.J., Barkhof F., Campi A., Dousset V., Franconi J.M., Gass A., Schreiber W., Miller D.H., Tofts P.S. A multicenter measurement of magnetization transfer ratio in normal white matter. J. Magn. Reson. Imaging 1999, 9(3):441-446.
4. Budde M.D., Kim J.H., Liang H.F., Russell J.H., Cross A.H., Song S.K. Axonal injury detected by in vivo diffusion tensor imaging correlates with neurological disability in a mouse model of multiple sclerosis. NMR Biomed. 2008, 21(6):589-597.
5. D'Arceuil H.E., Westmoreland S., de Crespigny A.J. An approach to high resolution diffusion tensor imaging in fixed primate brain. NeuroImage 2007, 35(2):553-565.
6. Deloire-Grassin M.S.A., Brochet B., Quesson B., Delalande C., Dousset V., Canioni P., Petry K.G. In vivo evaluation of remyelination in rat brain by magnetization transfer imaging. J. Neurol. Sci. 2000, 178(1):10-16.
7. Dula A.N., Gochberg D.F., Valentine H.L., Valentine W.M., Does M.D. Multiexponential T-2, magnetization transfer, and quantitative histology in white matter tracts of rat spinal cord. Magn. Reson. Med. 2010, 63(4):902-909.
8. Edzes H.T., Samulski E.T. Cross relaxation and spin diffusion in proton NMR of hydrated collagen. Nature 1977, 265(5594):521-523.
9. Felts P.A., Woolston A.M., Fernando H.B., Asquith S., Gregson N.A., Mizzi O.J., Smith K.J. Inflammation and primary demyelination induced by the intraspinal injection of lipopolysaccharide. Brain 2005, 128:1649-1666.
10. Gloor M., Scheffler K., Bieri O. Quantitative magnetization transfer imaging using balanced SSFP. Magn. Reson. Med. 2008, 60(3):691-700.
11. Gochberg D.F., Gore J.C. Quantitative imaging of magnetization transfer using an inversion recovery sequence. Magn. Reson. Med. 2003, 49(3):501-505.
12. Gochberg D.F., Gore J.C. Quantitative magnetization transfer imaging via selective inversion recovery with short repetition times. Magn. Reson. Med. 2007, 57(2):437-441.
13. Gochberg D.F., Kennan R.P., Gore J.C. Quantitative studies of magnetization transfer by selective excitation and T1 recovery. Magn. Reson. Med. 1997, 38(2):224-231.
14. Henkelman R.M., Huang X.M., Xiang Q.S., Stanisz G.J., Swanson S.D., Bronskill M.J. Quantitative interpretation of magnetization-transfer. Magn. Reson. Med. 1993, 29(6):759-766.
15. Klawiter E.C., Schmidt R.E., Trinkaus K., Liang H.F., Budde M.D., Naismith R.T., Song S.K., Cross A.H., Benzinger T.L. Radial diffusivity predicts demyelination in ex vivo multiple sclerosis spinal cords. NeuroImage 2011, 55(4):1454-1460.
16. Laule C., Leung E., Li D.K.B., Troboulsee A.L., Paty D.W., MacKay A.L., Moore G.R.W. Myelin water imaging in multiple sclerosis: quantitative correlations with histopathology. Mult. Scler. 2006, 12(6):747-753.
17. Li K., Zu Z.L., Xu J.Z., Janve V.A., Gore J.C., Does M.D., Gochberg D.F. Optimized inversion recovery sequences for quantitative T(1) and magnetization transfer imaging. Magn. Reson. Med. 2010, 64(2):491-500.
18. Lucchinetti C., Bruck W., Parisi J., Scheithauer B., Rodriguez M., Lassmann H. A quantitative analysis of oligodendrocytes in multiple sclerosis lesions - a study of 113 cases. Brain 1999, 122:2279-2295.
19. Mori S., Zhang J.Y. Principles of diffusion tensor imaging and its applications to basic neuroscience research. Neuron 2006, 51(5):527-539.
20. Odrobina E.E., Lam T.Y.J., Pun T., Midha R., Stanisz G.J. MR properties of excised neural tissue following experimentally induced clemyelination. NMR Biomed. 2005, 18(5):277-284.
21. Ou X., Gochberg D.F. MT effects and T1 quantification in single-slice spoiled gradient echo imaging. Magn. Reson. Med. 2008, 59(4):835-845.
22. Ou X.W., Sun S.W., Liang H.F., Song S.K., Gochberg D.F. The MT pool size ratio and the DTI radial diffusivity may reflect the myelination in shiverer and control mice. NMR Biomed. 2009, 22(5):480-487.
23. Prantner A.M., Bretthorst G.L., Neil J.J., Garbow J.R., Ackerman J.J.H. Magnetization transfer induced biexponential longitudinal relaxation. Magn. Reson. Med. 2008, 60(3):555-563.
24. Ramani A., Dalton C., Miller D.H., Tofts P.S., Barker G.J. Precise estimate of fundamental in-vivo MT parameters in human brain in clinically feasible times. Magn. Reson. Imaging 2002, 20(10):721-731.
25. Rausch M., Tofts P., Lervik P., Walmsley A., Mir A., Schubart A., Seabrook T. Characterization of white matter damage in animal models of multiple sclerosis by magnetization transfer ratio and quantitative mapping of the apparent bound proton fraction f. Mult. Scler. 2009, 15(1):16-27.
26. Ropele S., Seifert T., Enzinger C., Fazekas F. Method for quantitative imaging of the macromolecular H-1 fraction in tissues. Magn. Reson. Med. 2003, 49(5):864-871.
27. Schmierer K., Scaravilli F., Altmann D.R., Barker G.J., Miller D.H. Magnetization transfer ratio and myelin in postmortem multiple sclerosis brain. Ann. Neurol. 2004, 56(3):407-415.
28. Schmierer K., Tozer D.J., Scaravilli F., Altmann D.R., Barker G.J., Tofts P.S., Miller D.H. Quantitative magnetization transfer imaging in postmortem multiple sclerosis brain. J. Magn. Reson. Imaging 2007, 26(1):41-51.
29. Schmierer K., Wheeler-Kingshott C.A.M., Boulby P.A., Scaravilli F., Altmann D.R., Barker G.J., Tofts P.S., Miller D.H. Diffusion tensor imaging of post mortem multiple sclerosis brain. NeuroImage 2007, 35(2):467-477.
30. Shamy J.L., Carpenter D.M., Fong S.G., Murray E.A., Tang C.Y., Hof P.R., Rapp P.R. Alterations of white matter tracts following neurotoxic hippocampal lesions in macaque monkeys: a diffusion tensor imaging study. Hippocampus 2010, 20(8):906-910.
31. Sled J.G., Pike G.B. Quantitative interpretation of magnetization transfer in spoiled gradient echo MRI sequences. J. Magn. Reson. 2000, 145(1):24-36.
32. Sled J.G., Pike G.B. Quantitative imaging of magnetization transfer exchange and relaxation properties in vivo using MRI. Magn. Reson. Med. 2001, 46(5):923-931.
33. Song S.K., Sun S.W., Ramsbottom M.J., Chang C., Russell J., Cross A.H. Dysmyelination revealed through MRI as increased radial (but unchanged axial) diffusion of water. NeuroImage 2002, 17(3):1429-1436.
34. Song S.K., Yoshino J., Le T.Q., Lin S.J., Sun S.W., Cross A.H., Armstrong R.C. Demyelination increases radial diffusivity in corpus callosum of mouse brain. NeuroImage 2005, 26(1):132-140.
35. Sriram S., Yao S.Y., Natarajan C., Zhang F.L. Innate immunity mediated model of primary oligodendrogliopathy. Neurology 2012, 78.
36. Stikov N., Perry L.M., Mezer A., Rykhlevskaia E., Wandell B.A., Pauly J.M., Dougherty R.F. Bound pool fractions complement diffusion measures to describe white matter micro and macrostructure. NeuroImage 2011, 54(2):1112-1121.
37. Underhill H.R., Rostomily R.C., Mikheev A.M., Yuan C., Yarnykh V.L. Fast bound pool fraction imaging of the in vivo rat brain: association with myelin content and validation in the C6 glioma model. NeuroImage 2011, 54(3):2052-2065.
38. Viola P., Wells W.M. Alignment by maximization of mutual information. Int. J. Comput. Vis. 1997, 24(2):137-154.