Do cerebral microbleeds increase the risk of intracerebral hemorrhage after thrombolysis for acute ischemic stroke?

International Journal of Stroke

Volumn 8, Issue 3, 2013, Pages

  Charidimou, Andreas ^a   Fox, Zoe ^b,c   Werring, David J ^a  

^a NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADVERSE OUTCOME; BLOOD CLOT LYSIS; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CARDIOVASCULAR RISK; CEREBROVASCULAR ACCIDENT; HUMAN; LETTER; META ANALYSIS; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PREDICTION; PRIORITY JOURNAL; SYSTEMATIC REVIEW; VASCULAR AMYLOIDOSIS;

HUMANS; INTRACRANIAL HEMORRHAGES; STROKE; THROMBOLYTIC THERAPY;

EID: 84875249107     PISSN: 17474930     EISSN: 17474949     Source Type: Journal    
DOI: 10.1111/ijs.12048     Document Type: Letter

References (7)

1. Shoamanesh A, Kwok CS, Lim PA, Benavente OR. Postthrombolysis intracranial hemorrhage risk of cerebral microbleeds in acute stroke patients: a systematic review and meta-analysis. Int J Stroke 2012; doi: 10.1111/j.1747-4949.2012.00869.x
2. European Stroke Conference. 21st Conference, Lisbon, May 2012: abstract E-book. Cerebrovasc Dis 2012; 33(Suppl. 2):1-2.
3. Charidimou A, Kakar P, Fox Z, Werring DJ. Cerebral microbleeds and the risk of intracerebral haemorrhage after thrombolysis for acute ischaemic stroke: systematic review and meta-analysis. J Neurol Neurosurg Psychiatry 2012; doi: 10.1136/jnnp-2012-303379
4. Davies HT, Crombie IK, Tavakoli M. When can odds ratios mislead? BMJ 1998; 316:989-991.
5. McCarron MO, Nicoll JA. Cerebral amyloid angiopathy and thrombolysis-related intracerebral haemorrhage. Lancet Neurol 2004; 3:484-492.
6. Trouillas P, von Kummer R. Classification and pathogenesis of cerebral hemorrhages after thrombolysis in ischemic stroke. Stroke 2006; 37:556-561.
7. Ly JV, Rowe CC, Villemagne VLetal. Cerebral beta-amyloid detected by Pittsburgh compound B positron emission topography predisposes to recombinant tissue plasminogen activator-related hemorrhage. Ann Neurol 2010; 68:959-962.