Efficacy of Bacillus clausii strain UBBC-07 in the treatment of patients suffering from acute diarrhoea

Beneficial Microbes

Volumn 4, Issue 2, 2013, Pages 211-216

  Ratna Sudha, M ^a   Bhonagiri, S ^b   Asin Kumar, M ^c  

^a Unique Biotech Limited   (India)

^b Medipoint Hospital Pvt Ltd   (India)

^c LOKMANYA TILAK MUNICIPAL GENERAL HOSPITAL   (India)

Author keywords

Anti diarrhoea; Bacillus clausii; Probiotics.

Indexed keywords

ALANINE AMINOTRANSFERASE; CREATININE; PROBIOTIC AGENT;

ABDOMINAL PAIN; ACUTE DIARRHEA; ADULT; ADVERSE OUTCOME; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANTIDIARRHEAL ACTIVITY; ARTICLE; BACILLUS; BACILLUS CLAUSII; BACTERIAL STRAIN; BLOOD PRESSURE; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CLINICAL EFFECTIVENESS; CLINICAL TRIAL; CREATININE BLOOD LEVEL; DEFECATION; DISEASE DURATION; DRUG EFFICACY; DRUG SAFETY; DRUG TREATMENT FAILURE; FECES ANALYSIS; FEMALE; HUMAN; LOOSE FECES; MALE; MICROSCOPY; OUTCOME ASSESSMENT; PHASE 2 CLINICAL TRIAL; PHYSICAL EXAMINATION; PROSPECTIVE STUDY; PULSE RATE; SIDE EFFECT; TREATMENT DURATION;

EID: 84875247882     PISSN: 18762883     EISSN: 18762891     Source Type: Journal    
DOI: 10.3920/BM2012.0034     Document Type: Article

References (24)

1. Benoni, G., Marcer, V., Cuzzolin, L. and Raimo, F., 1984. Antibiotic administration and oral bacterial therapy in infants. Chemioterapia 3: 291-294.
2. Casburn-Jones, A.C. and Farthing, M.J.G., 2004. Management of infectious diarrhea. Gut 53: 296-305.
3. Casula, G. and Cutting, S.M., 2002. Bacillus probiotics: spore germination in the gastrointestinal tract. Applied and Environmental Microbiology 68: 2344-2352
4. Ciprandi, G., Vizzaccaro, A., Cirillo, I. and Tosca, M.A., 2005. Bacillus clausii exerts immuno-modulatory activity in allergic subjects: a pilot study. European Annals of Allergy and Clinical Immunology 37: 129-134.
5. DeVrese, M. and Marteau, P.R., 2007. Probiotics and prebiotics: effects on diarrhea. Journal of Nutrition 137: 803-811.
6. Duc, L.H., Hong, H.A. and Cutting, S.M., 2003a. Germination of the spore in the gastrointestinal tract provides a novel route for heterologus antigen presentation. Vaccine 21: 4215-4224.
7. Duc, L.H., Hong, H.A., Fairweather, N., Ricca, E. and Cutting, S.M., 2003b. Bacterial spores as vaccine vehicles. Infectious Immunology 71: 2810-2818.
8. Fuller, R., 1991. Probiotics in human medicine. Gut 32: 439-442.
9. Hatanaka, M., Nakamura, Y., Maathuis, A.J.H., Venema, K., Murota, I. and Yamamoto, N., 2012. Influence of Bacillus subtilis C-3102 on microbiota in a dynamic in vitro model of the gastrointestinal tract simulating human conditions. Beneficial Microbes 3: 229-236.
10. Hoyles, L., Honda, H., Logan, N.A., Halket, G., La Ragione, R.M. and McCartney, A.L., 2012. Recognition of greater diversity of Bacillus species and related bacteria in human faeces. Research in Microbiology 163: 3-13.
11. Isolauri, E., 2003. Probiotics for infectious diarrhea. Gut 52: 436-437.
12. Johnston, B.C., Supina, A.L. and Vohra, S., 2006. Probiotics for pediatric antibiotic-associated diarrhea: a meta-analysis of randomized placebo-controlled trials. Canadian Medical Association Journal 175: 377-383.
13. 30 strain of Bacillus coagulans in a dynamic in vitro model of the stomach and small intestine. Beneficial Microbes 1: 31-36.
14. Marseglia, G.L., Tosca, M., Cirillo, I., Licari, A., Leone, M., Marseglia, A., Castellazzi, A.M. and Ciprandi, G., 2007. Efficacy of Bacillus clausii spores in the prevention of recurrent respiratory infections in children: a pilot study. Therapeutics and Clinical Risk Management 3: 13-17.
15. Manatsathit, S., Dupont, H.L., Farthing, M., Kositchaiwat, C., Leelakusilvongm, S., Ramakrishna, B.S., Sabra, A., Speelman, P. and Surangsrirat, S., 2002. Guideline for the management of acute diarrhea in adults. Journal of Gastroenterology and Hepatology 17 Suppl. 1: S54-S71.
16. Mazza, P., 1994. The use of Bacillus subtilis as an antidiarrhoeal microorganism. Bollettino Chimico Farmaceutico 133: 3-18.
17. Nista, E.C., Candelli, M., Cremonili, F., Cazzato, I.A., Zocco, M.A., Franceschi, F., Cammarota, G., Gasbarrini, G. and Gasbarrini, A., 2004. Bacillus clausii therapy to reduce side-effects of anti- Helicobacter pylori treatment: randomized, double-blind, placebo controlled trial. Alimentary Pharmacology and Therapeutics 20: 1181-1188.
18. Salminen, S. and Deighton, M., 1992. Lactic acid bacteria in the gut in normal and disordered states. Digestive Diseases 10: 227-238.
19. Sazawal, S., Hiremath, G., Dhingra, U., Malik, P., Deb, S. and Black, R.E., 2006. Efficacy of probiotics in prevention of acute diarrhea: a meta-analysis of masked, randomized, placebo-controlled trials. The Lancet Infectious Diseases 6: 374-382.
20. Shornikova, A.V., Casas, I.A. and Isolauri, E., 1997. Lactobacillus reuteri as a therapeutic agent in acute diarrhea in young children. Journal of Pediatric Gastroenterology and Nutrition 24: 399-404.
21. Ratna Sudha, M. and Bhonagiri, S., 2012. Efficacy of Bacillus coagulans strain Unique IS-2 in the treatment of patients with acute diarrhea. International Journal of Probiotics and Prebiotics 7: 33-38.
22. Ratna Sudha, M., Bhonagiri, S. and Kumar, M.S., 2012. Oral consumption of potential probiotic Saccharomyces boulardii strain Unique 28 in patients with acute diarrhoea: a clinical report. Beneficial Microbes 3: 145-150.
23. Szajewska, H. and Mrukowicz, J.Z., 2001. Probiotics in the treatment and prevention of acute infectious diarrhea in infants and children: a systematic review of published randomized, double-blind, placebocontrolled trials. Journal of Pediatric Gastroenterology and Nutrition 33: 17-25.
24. World Health Organization (WHO), 1990. The treatment of diarrhoea. A manual for physicians and other senior health workers. World Health Organization, Geneva, Switzerland. Available at: http:// whqlibdoc.who.int/publications/2005/9241593180.pdf.