Lactobacillus reuteri as a therapeutic agent in acute diarrhea in young children

Journal of Pediatric Gastroenterology and Nutrition

Volumn 24, Issue 4, 1997, Pages 399-404

  Shornikova, Aino Vieno ^a   Casas, Ivan A ^b   Isolauri, Erika ^a   Mykkänen, Hannu ^c   Vesikari, Timo ^a  

^a TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^b BioGaia Biologics Inc   (United States)

^c UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Diarrhea; Gut microflora; Lactobacillus reuteri; Rotavirus

Indexed keywords

ACUTE DIARRHEA; ARTICLE; BACTERIAL COLONIZATION; BACTERIUM ISOLATION; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FECES ANALYSIS; FOOD COMPOSITION; HUMAN; INFANT; INTESTINE FLORA; LACTOBACILLUS; LACTOBACILLUS REUTERI; ORAL DRUG ADMINISTRATION; PRESCHOOL CHILD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; ROTAVIRUS; STOMACH PROTECTION;

ACUTE DISEASE; ANTIBODIES, BACTERIAL; CHILD, PRESCHOOL; DIARRHEA, INFANTILE; DIGESTIVE SYSTEM; HUMANS; IMMUNOGLOBULIN A; INFANT; LACTOBACILLUS; PLACEBOS; ROTAVIRUS; ROTAVIRUS INFECTIONS;

EID: 0030951499     PISSN: 02772116     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005176-199704000-00008     Document Type: Article

References (26)

1. Fuller R. Probiotics in human medicine. Gut 1991;32:439-42.
2. Salminen S, Deighton M. Lactic acid bacteria in the gut in normal and disordered states. Dig Dis 1992;10:227-38.
3. Tazume S, Ozawa A, Yamamoto T, et al. Ecological study on the intestinal bacterial flora of patients with diarrhea. Clin Infect Dis 1993;16(2 suppl):77-82S.
4. Mitsuoka T. The human gastrointestinal tract. In: Wood BJB, ed. The lactic acid bacteria, volume 1. The lactic acid bacteria in health and disease. London: Elsevier, 1992;1:69-114.
5. Salminen S, Isolauri E, Onnela T. Gut flora in normal and disordered states. Chemotherapy 1995;41(suppl):5-15.
6. Pearce JL, Hamilton JR. Controlled trial of orally administered lactobacilli in acute infantile diarrhea. J Pediatr 1974; 84:261-2.
7. Brunser O, Araya M, Espinoza J, Guesry PR, Secretin MC, Pacheco I. Effect of an acidified milk on diarrhea and the carrier state in infants of low socio-economic stratum. Acta Paediatr Scand 1989;78:259-64.
8. Boudraa G, Touhami M, Pochart P, Soltana R, Mary J-Y, Desjeux J-F. Effect of feeding yogurt versus milk in children with persistent diarrhea. J. Pediatr Gastroenterol Nutr 1990; 11:509-12.
9. Isolauri E, Juntunen M, Rautanen T, Sillanaukee P, Koivula T. A human lactobacillus strain (Lactabacillus casei sp strain GG) promotes recovery from acute diarrhea in children. Pediatrics 1991;88:90-7.
10. Kaila M, Isolauri E, Soppi E, Virtanen E, Laine S, Arvilommi H. Enhancement of the circulating antibody secreting cell response in human diarrhea by a human lactobacillus strain. Pediatr Res 1992;32:141-4.
11. Majamaa H, Isolauri E, Saxelin M, Vesikari T. Lactic acid bacteria in the treatment of acute rotavirus gastroenteritis. J Pediatr Gastroenterol Nutr 1995;20:333-8.
12. Kandler O, Stetter J, Kohl R. Lactobacillus reuteri sp. Nov., a new species of heterofermentative lactobacilli. Zbl Bakr Abt Orig 1980;C1:264-9.
13. Axelson LT, Chung TC, Dobrogosz WJ, Lindgren SE. Production of a broad spectrum antimicrobial substance by Lactobacillus reuteri. Microb Ecology Health Dis 1989;2:131-6.
14. Wolf BW, Garleb KA, Ataya DG, Casas IA. Safety and tolerance of Lactobacillus reuteri in healthy adult male subjects. Microb Ecology Health Dis 1995;8:41-50.
15. Fabia R, Ar'Rajab A, Johansson M-L, et al. The effect of exogenous administration of lactobacillus reuteri R2LC and oat fiber on acetic acid-induced colitis in the rat. Scand J Gastroenterol 1993;28:155-62.
16. Isolauri E, Vesikari T. Oral rehydration, rapid feeding, and cholestyramine for treatment of acute diarrhea. J Pediatr Gastroenterol Nutr 1985;4:366-74.
17. Rautanen T, El-Radhi S, Vesikari T. Clinical experience with a hypotonic oral rehydration solution in acute diarrhea. Acta Paediatr 1993;82:52-4.
18. Isolauri E, Joensuu J, Suomalainen H, Luomala M, Vesikari T. Improved immunogenicity of oral DxRR reassortant rotavirus vaccine by Lactobacillus casei GG. Vaccine 1995;13: 310-2.
19. Isolauri E, Kaila M, Mykkänen H, Ling WH, Salminen S. Oral bacteriotherapy for viral gastroenteritis. Dig Dis Sci 1994; 39:2595-600.
20. Ling WH, Hänninen O, Mykkänen H, Heikura M, Salminen S, von Wright A. Colonization and fecal enzyme activities after oral Lactobacillus GG administration in elderly nursing home residents. Ann Nutr Metab 1992;36:162-6.
21. Goldin BR, Gorbach SL, Saxelin M, Bakarat S, Gualtieri L, Salminen S. Survival of lactobacillus species (strain GG) in human gastrointestinal tract. Dig Dis Sci 1992;37:121-8.
22. Lidbeck A, Gustafsson J-Å, Nord CE. Impact of lactobacillus acidophilus supplements on the human oropharyngeal and intestinal microflora. Scand J Infect Dis 1987;19:531-7.
23. Isolauri E, Majamaa H, Arvola T, Rantala I, Virtanen E, Arvilommi H. Lactobacillus casei strain GG reverses increased intestinal permeability induced by cow milk in suckling rats. Gastroenterology 1993;105:1643-50.
24. Isolauri E, Kaila M, Arvola T, et al. Diet during rotavirus enteritis affects jejunal permeability to macromolecules in suckling rats. Pediatr Res 1993;33:548-53.
25. Perdigon G, Alvarex S, Nader De Macias M, Roux M, Pesce de Ruiz Holgado A. The oral administration of lactic acid bacteria increases the mucosal intestinal immunity in response to enteropathogens. J Food Protec 1990;53:404-10.
26. Perdigon G, Medici M, Bibas Bonet de Jorrat ME, Valverde de Budeguer M, Pesce de Ruiz Holgado A. Immunomodulating effects of lactic acid bacteria on mucosal and humoral immunity. Int J Immunother 1993;9:29-52.