Autoantibodies to 60kDa SS-A/Ro yield a specific nuclear myriad discrete fine speckled immunofluorescence pattern

Journal of Immunological Methods

Volumn 390, Issue 1-2, 2013, Pages 35-40

  Dellavance, Alessandra ^a   Alvarenga, Rossana Rassi ^b   Rodrigues, Silvia Helena ^a,b   Barbosa, Silvia Helena ^a   Camilo, Amandia Cristina Pinto ^a   Shiguedomi, Herika Santiago Okamoto ^a   Rodrigues, Silvia Sanchez ^a   Silva, Cristiane Gallindo ^a   Andrade, Luis Eduardo Coelho ^a,b  

^a Fleury   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Antinuclear antibodies; Autoantibodies; Sj gren's syndrome; SS A Ro; Systemic lupus erythematosus

Indexed keywords

ANTINUCLEAR ANTIBODY; CENTROMERE PROTEIN F; NUCLEAR MITOTIC APPARATUS PROTEIN 1; NUCLEAR PROTEIN; PROTEIN; RO ANTIBODY; UNCLASSIFIED DRUG;

ANTIBODY SCREENING; ANTIBODY SPECIFICITY; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; HEP 2 CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOREACTIVITY; NUCLEAR MYRIAD DISCRETE FINE SPECKLED IMMUNOFLUORESCENCE PATTERN; PRIORITY JOURNAL;

ANTIBODIES, ANTINUCLEAR; AUTOANTIBODIES; BLOTTING, WESTERN; CELL LINE, TUMOR; CELL NUCLEUS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MOLECULAR WEIGHT; REPRODUCIBILITY OF RESULTS;

EID: 84875241905     PISSN: 00221759     EISSN: 18727905     Source Type: Journal    
DOI: 10.1016/j.jim.2013.01.006     Document Type: Article

References (34)

1. Alspaugh M.A., Tan E.M. Antibodies to cellular antigens in Sjogren's syndrome. J. Clin. Invest. 1975, 55:1067.
2. Andrade L.E., Chan E.K., Raska I., Peebles C.L., Roos G., Tan E.M. Human autoantibody to a novel protein of the nuclear coiled body: immunological characterization and cDNA cloning of p80-coilin. J. Exp. Med. 1991, 173:1407.
3. Andrade L.E., Chan E.K., Peebles C.L., Tan E.M. Two major autoantigen-antibody systems of the mitotic spindle apparatus. Arthritis Rheum. 1996, 39:1643.
4. Casiano C.A., Humbel R.L., Peebles C., Covini G., Tan E.M. Autoimmunity to the cell cycle-dependent centromere protein p330d/CENP-F in disorders associated with cell proliferation. J. Autoimmun. 1995, 8:575.
5. Chan E.K., Hamel J.C., Buyon J.P., Tan E.M. Molecular definition and sequence motifs of the 52-kD component of human SS-A/Ro autoantigen. J. Clin. Invest. 1991, 87:68.
6. Chan E.K., Imai H., Hamel J.C., Tan E.M. Human autoantibody to RNA polymerase I transcription factor hUBF. Molecular identity of nucleolus organizer region autoantigen NOR-90 and ribosomal RNA transcription upstream binding factor. J. Exp. Med. 1991, 174:1239.
7. Christian C.L., Elkon K.B. Autoantibodies to intracellular proteins. Clinical and biologic significance. Am. J. Med. 1986, 80:53.
8. Clark G., Reichlin M., Tomasi T.B. Characterization of a soluble cytoplasmic antigen reactive with sera from patients with systemic lupus erythematosus. J. Immunol. 1969, 102:117.
9. Dellavance A., Viana V.S., Leon E.P., Bonfa E.S., Andrade L.E., Leser P.G. The clinical spectrum of antinuclear antibodies associated with the nuclear dense fine speckled immunofluorescence pattern. J. Rheumatol. 2005, 32:2144.
10. Dellavance A., Gallindo C., Soares M.G., da Silva N.P., Mortara R.A., Andrade L.E. Redefining the Scl-70 indirect immunofluorescence pattern: autoantibodies to DNA topoisomerase I yield a specific compound immunofluorescence pattern. Rheumatology (Oxford) 2009, 48:632.
11. Fritzler M.J., Hamel J.C., Ochs R.L., Chan E.K. Molecular characterization of two human autoantigens: unique cDNAs encoding 95- and 160-kD proteins of a putative family in the Golgi complex. J. Exp. Med. 1993, 178:49.
12. Fritzler M.J., Lung C.C., Hamel J.C., Griffith K.J., Chan E.K. Molecular characterization of Golgin-245, a novel Golgi complex protein containing a granin signature. J. Biol. Chem. 1995, 270:31262.
13. Gonzalez C., Garcia-Berrocal B., Herraez O., Navajo J.A., Gonzalez-Buitrago J.M. Anti-nucleosome, anti-chromatin, anti-dsDNA and anti-histone antibody reactivity in systemic lupus erythematosus. Clin. Chem. Lab. Med. 2004, 42:266.
14. Griffith K.J., Chan E.K., Lung C.C., Hamel J.C., Guo X., Miyachi K., Fritzler M.J. Molecular cloning of a novel 97-kd Golgi complex autoantigen associated with Sjogren's syndrome. Arthritis Rheum. 1997, 40:1693.
15. Infante C., Ramos-Morales F., Fedriani C., Bornens M., Rios R.M. GMAP-210, a cis-Golgi network-associated protein, is a minus end microtubule-binding protein. J. Cell Biol. 1999, 145:83.
16. Khan S., Alvi A., Holding S., Kemp M.L., Raine D., Dore P.C., Sewell W.A. The clinical significance of antinucleolar antibodies. J. Clin. Pathol. 2008, 61:283.
17. Kumar Y., Bhatia A., Minz R.W. Antinuclear antibodies and their detection methods in diagnosis of connective tissue diseases: a journey revisited. Diagn. Pathol. 2009, 4:1.
18. Mariz H.A., Sato E.I., Barbosa S.H., Rodrigues S.H., Dellavance A., Andrade L.E. Pattern on the antinuclear antibody-HEp-2 test is a critical parameter for discriminating antinuclear antibody-positive healthy individuals and patients with autoimmune rheumatic diseases. Arthritis Rheum. 2011, 63:191.
19. Mattioli M., Reichlin M. Heterogeneity of RNA protein antigens reactive with sera of patients with systemic lupus erythematosus. Description of a cytoplasmic nonribosomal antigen. Arthritis Rheum. 1974, 17:421.
20. Meroni P.L., Schur P.H. ANA screening: an old test with new recommendations. Ann. Rheum. Dis. 2010, 69:1420.
21. Migliorini P., Baldini C., Rocchi V., Bombardieri S. Anti-Sm and anti-RNP antibodies. Autoimmunity 2005, 38:47.
22. Nozawa K., Fritzler M.J., Chan E.K. Unique and shared features of Golgi complex autoantigens. Autoimmun. Rev. 2005, 4:35.
23. Ochs R.L., Stein T.W., Peebles C.L., Gittes R.F., Tan E.M. Autoantibodies in interstitial cystitis. J. Urol. 1994, 151:587.
24. Ouchterlony O. Diffusion-in-gel methods for immunological analysis. Prog. Allergy 1958, 5:1.
25. Peek R., Pruijn G.J., van der Kemp A.J., van Venrooij W.J. Subcellular distribution of Ro ribonucleoprotein complexes and their constituents. J. Cell Sci. 1993, 106(Pt 3):929.
26. Reimer G., Raska I., Scheer U., Tan E.M. Immunolocalization of 7-2-ribonucleoprotein in the granular component of the nucleolus. Exp. Cell Res. 1988, 176:117.
27. Satoh M., Chan E.K., Ho L.A., Rose K.M., Parks C.G., Cohn R.D., Jusko T.A., Walker N.J., Germolec D.R., Whitt I.Z., Crockett P.W., Pauley B.A., Chan J.Y., Ross S.J., Birnbaum L.S., Zeldin D.C., Miller F.W. Prevalence and sociodemographic correlates of antinuclear antibodies in the United States. Arthritis Rheum. 2012, 64:2319.
28. Schulte-Pelkum J., Fritzler M., Mahler M. Latest update on the Ro/SS-A autoantibody system. Autoimmun. Rev. 2009, 8:632.
29. Seelig H.P., Schranz P., Schroter H., Wiemann C., Renz M. Macrogolgin-a new 376kD Golgi complex outer membrane protein as target of antibodies in patients with rheumatic diseases and HIV infections. J. Autoimmun. 1994, 7:67.
30. Solomon D.H., Kavanaugh A.J., Schur P.H. Evidence-based guidelines for the use of immunologic tests: antinuclear antibody testing. Arthritis Rheum. 2002, 47:434.
31. Takasaki Y., Fishwild D., Tan E.M. Characterization of proliferating cell nuclear antigen recognized by autoantibodies in lupus sera. J. Exp. Med. 1984, 159:981.
32. Tan E.M. Autoantibodies to nuclear antigens (ANA): their immunobiology and medicine. Adv. Immunol. 1982, 33:167.
33. Tan E.M., Feltkamp T.E., Smolen J.S., Butcher B., Dawkins R., Fritzler M.J., Gordon T., Hardin J.A., Kalden J.R., Lahita R.G., Maini R.N., McDougal J.S., Rothfield N.F., Smeenk R.J., Takasaki Y., Wiik A., Wilson M.R., Koziol J.A. Range of antinuclear antibodies in "healthy" individuals. Arthritis Rheum. 1997, 40:1601.
34. Whitehead C.M., Winkfein R.J., Fritzler M.J., Rattner J.B. The spindle kinesin-like protein HsEg5 is an autoantigen in systemic lupus erythematosus. Arthritis Rheum. 1996, 39:1635.