Simultaneous determination of renal plasma flow and glomerular filtration rate in conscious mice using dual bolus injection

Journal of Pharmacological and Toxicological Methods

Volumn 67, Issue 3, 2013, Pages 187-193

  Sällström, Johan ^a,b   Fridén, Markus ^a,c  

^a UPPSALA UNIVERSITY   (Sweden)

^b KAROLINSKA INSTITUTE   (Sweden)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

Angiotensin II; AT1 receptor; Conscious; Filtration fraction; Glomerular filtration rate; Renal plasma flow

Indexed keywords

4 AMINOHIPPURIC ACID; CANDESARTAN; INULIN; METHOXYINULIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTERIAL BLOOD; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; BOLUS INJECTION; CAROTID ARTERY; CONSCIOUSNESS; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; GLOMERULUS FILTRATION; GLOMERULUS FILTRATION RATE; KIDNEY PLASMA FLOW; KIDNEY VEIN; LIQUID SCINTILLATION COUNTING; MOUSE; NONHUMAN; PLASMA CLEARANCE; TIME SERIES ANALYSIS;

ANIMALS; CARBON RADIOISOTOPES; CROSS-OVER STUDIES; FEMALE; GLOMERULAR FILTRATION RATE; INULIN; MALE; MICE; MICE, INBRED C57BL; P-AMINOHIPPURIC ACID; RENAL PLASMA FLOW; SCINTILLATION COUNTING; TRITIUM;

EID: 84875237261     PISSN: 10568719     EISSN: 1873488X     Source Type: Journal    
DOI: 10.1016/j.vascn.2013.01.010     Document Type: Article

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