Eleutherine indica L. accelerates in vivo cutaneous wound healing by stimulating Smad-mediated collagen production

Journal of Ethnopharmacology

Volumn 146, Issue 2, 2013, Pages 490-494

  Upadhyay, Aadesh ^a,b   Chattopadhyay, Pronobesh ^a   Goyary, Danswrang ^a   Mazumder, Papiya Mitra ^b   Veer, Vijay ^a  

^a Defence R D Organization   (India)

^b BIRLA INSTITUTE OF TECHNOLOGY   (India)

Author keywords

Collagen; Eleutherine indica L.; Histopathology; Hydroxyproline; Western blot; Wound healing

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR RECEPTOR; COLLAGEN TYPE 3; ELEUTHERINE INDICA EXTRACT; GENTAMICIN; HYDROXYPROLINE; METHANOL; PLANT EXTRACT; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD4 PROTEIN; SMAD7 PROTEIN; UNCLASSIFIED DRUG; WOUND HEALING PROMOTING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLLAGEN SYNTHESIS; CONTROLLED STUDY; DEBRIDEMENT; DRUG ISOLATION; ELEUTHERINE INDICA; EXCISION; GRANULATION TISSUE; HISTOPATHOLOGY; HYDROGEL; IN VIVO STUDY; IRIDACEAE; KERATINIZATION; MALE; MOUSE; NONHUMAN; PHYTOCHEMISTRY; RAT; SKIN INJURY; SKIN IRRITATION; SKIN TOXICITY; WESTERN BLOTTING; WOUND CONTRACTION; WOUND HEALING;

ANIMALS; COLLAGEN; COLLAGEN TYPE III; HYDROXYPROLINE; IRIDACEAE; MALE; MICE; PHYTOTHERAPY; PLANT EXTRACTS; RATS; RATS, WISTAR; SKIN; SMAD PROTEINS; WOUND HEALING;

ELEUTHERINE; RATTUS NORVEGICUS;

EID: 84875229826     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.01.012     Document Type: Article

References (19)

1. T.M.A Alves, H. Kloos, and C.L. Zani Eleutherinone, a novel fungitoxic naphthoquinone from Eleutherine bulbosa (Iridaceae) Memrias do Instituto Oswaldo Cruz, Rio de Janeiro 98 2003 709 712 (Pubitemid 38019597)
2. M.M. Bradford A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Analytical Biochemistry 72 1976 248 254
3. B.O.T. Ifesan, C. Hamtasin, W. Mahabusarakam, and S.P. Voravuthikunchai Inhibitory effect of Eleutherine americana Merr. extract on Staphylococcus aureus isolated from foods Journal of Food Science 74 2009 31 36
4. L. Jie, J. Chen, and R. Kirsner Pathophysiology of acute wound healing Clinics in Dermatology 25 2007 9 18 (Pubitemid 46177460)
5. K.R. Khandelwal Practical Pharmacognosy 11th ed. 2004 Nirali Prakashan Pune pp. 149-156
6. T. Kondo, and Y. Ishida Molecular pathology of wound healing Forensic Science International 203 2010 93 98
7. B. Kumar, M. Vijayakumar, R. Govindarajan, and P. Pushpangadan Ethnopharmacological approaches to wound healing-exploring medicinal plants of India Journal of Ethnopharmacology 114 2007 103 113 (Pubitemid 47539834)
8. J. Lin, T. Puckree, and T.P. Mvelase Anti-diarrhoeal evaluation of some medicinal plants used by zulu traditional healers Journal of Ethnopharmacology 79 2002 53 56 (Pubitemid 34017240)
9. J. Massague, and R.R. Gomis The logic of TGF-β signaling FEBS Letters 580 2006 2811 2820
10. R.E. Neuman, and M.A. Logan The determination of hydroxyproline Journal of Biological Chemistry 184 1950 299 306
11. S. Paramapojn, M. Ganzera, W. Gristanapan, and H. Stuppner Analysis of naphthoquinone derivatives in the Asian medicinal plant Eleutherine americana by RP-HPLC and LC-MS Journal of Pharmaceutical and Biomedical Analysis 47 2008 990 993
12. F. Qui, J.Z. Xu, W.J. Duan, G.X. Qu, N.L. Wang, and X.S. Yao New constituents from Eleutherine americana Chemical Journal of Chinese Universities 26 2005 2057 2060
13. R. Sanwal, and A.K. Chaudhary Wound healing and antimicrobial potential of Carissa spinarum Linn. in albino mice Journal of Ethnopharmacology 135 2011 792 796
14. M. Schafer, and S. Werner Oxidative stress in normal and impaired wound repair Pharmacological Research 58 2008 165 171
15. M. Schiller, D. Javelaud, and A. Mauviel TGF-β-induced SMAD signaling and gene regulation: consequences for extracellular matrix remodeling and wound healing Journal of Dermatological Science 35 2004 83 92 (Pubitemid 38969031)
16. S.H. Song, H.Y. Min, A.R. Han, J.W. Nam, E.K. Seo, S.W. Park, S.H. Lee, and S.K. Lee Suppression of inducible nitric oxide synthase by (-)-isoeleutherin from the bulbs of Eleutherine americana through the regulation of NF-κB activity International Immunopharmacology 9 2009 298 302
17. R. Thakur, N. Jain, R. Pathak, and S.S. Sandhu Practices in wound healing studies of plants Evidence-Based Complementary and Alternative Medicine 2011 1 17
18. L.F. Villegas, I.D. Fernfindez, H. Maldonado, R. Torres, A. Zavaleta, A.J. Vaisberg, and G.B. Hammond Evaluation of the wound-healing activity of selected traditional medicinal plants from Peril Journal of Ethnopharmacology 55 1997 193 200 (Pubitemid 27122307)
19. J. Xu, F. Qui, W. Duan, G. Qu, N. Wang, and X. Yao New bioactive constituents from Eleutherine americana Frontiers of Chemistry in China 3 2006 320 323 (Pubitemid 44495705)