Inserting needles into the body: A meta-analysis of brain activity associated with acupuncture needle stimulation

Journal of Pain

Volumn 14, Issue 3, 2013, Pages 215-222

  Chae, Younbyoung ^a,b   Chang, Dong Seon ^a,c   Lee, Soon Ho ^a   Jung, Won Mo ^b   Lee, In Seon ^a   Jackson, Stephen ^b,d   Kong, Jian ^e   Lee, Hyangsook ^a   Park, Hi Joon ^a   Lee, Hyejung ^a   Wallraven, Christian ^b  

^a Kyung Hee University   (South Korea)

^b Korea University   (South Korea)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Acupuncture; analgesia; functional magnetic resonance imaging (fMRI); meta analysis; pain

Indexed keywords

ACUPUNCTURE; AMYGDALOID NUCLEUS; ANTERIOR CINGULATE; ARTICLE; BRAIN FUNCTION; CAUDATE NUCLEUS; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; IMAGE ANALYSIS; INSULA; LIMBIC CORTEX; META ANALYSIS; POSTERIOR CINGULATE; PREFRONTAL CORTEX; PRIMARY SOMATOSENSORY CORTEX; SECONDARY SOMATOSENSORY CORTEX; SENSORIMOTOR CORTEX; TACTILE STIMULATION; THALAMUS;

ACUPRESSURE; ANIMALS; BRAIN; BRAIN MAPPING; DATABASES, FACTUAL; HUMANS; LIKELIHOOD FUNCTIONS; MAGNETIC RESONANCE IMAGING; NEEDLES; PAIN; PHYSICAL STIMULATION;

EID: 84875226209     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2012.11.011     Document Type: Article

References (64)

1. M. Amanzio, F. Benedetti, C.A. Porro, S. Palermo, and F. Cauda Activation likelihood estimation meta-analysis of brain correlates of placebo analgesia in human experimental pain Hum Brain Mapp 2012 10.1002/hbm.21471
2. A.V. Apkarian, M.C. Bushnell, R.D. Treede, and J.K. Zubieta Human brain mechanisms of pain perception and regulation in health and disease Eur J Pain 9 2005 463 484
3. J.A. Astin Why patients use alternative medicine: Results of a national study JAMA 279 1998 1548 1553
4. L.R. Becerra, H.C. Breiter, M. Stojanovic, S. Fishman, A. Edwards, A.R. Comite, R.G. Gonzalez, and D. Borsook Human brain activation under controlled thermal stimulation and habituation to noxious heat: An fMRI study Magn Reson Med 41 1999 1044 1057
5. F. Beissner, R. Deichmann, C. Henke, and K.J. Bar Acupuncture-deep pain with an autonomic dimension? Neuroimage 60 2012 653 660
6. F. Beissner, and C. Henke Methodological problems in FMRI studies on acupuncture: A critical review with special emphasis on visual and auditory cortex activations Evid Based Complement Alternat Med 2011 10.1093/ecam/nep154
7. B.M. Berman, H.M. Langevin, C.M. Witt, and R. Dubner Acupuncture for chronic low back pain N Engl J Med 363 2010 454 461
8. U. Bingel, M. Quante, R. Knab, B. Bromm, C. Weiller, and C. Buchel Subcortical structures involved in pain processing: Evidence from single-trial fMRI Pain 99 2002 313 321
9. R.L. Buckner, J.R. Andrews-Hanna, and D.L. Schacter The brain's default network: Anatomy, function, and relevance to disease Ann N Y Acad Sci 1124 2008 1 38
10. A. Campbell Point specificity of acupuncture in the light of recent clinical and imaging studies Acupunct Med 24 2006 118 122
11. C. Carlsson Acupuncture mechanisms for clinically relevant long-term effects-reconsideration and a hypothesis Acupunct Med 20 2002 82 99
12. P. Cesaro, M.W. Mann, J.L. Moretti, G. Defer, B. Roualdes, J.P. Nguyen, and J.D. Degos Central pain and thalamic hyperactivity: A single photon emission computerized tomographic study Pain 47 1991 329 336
13. Y. Chae, H.J. Park, D.H. Hahm, M. Hong, E. Ha, H.K. Park, and H. Lee fMRI review on brain responses to acupuncture: The limitations and possibilities in traditional Korean acupuncture Neurol Res 29 Suppl 1 2007 S42 S48
14. Z.H. Cho, S.C. Chung, J.P. Jones, J.B. Park, H.J. Park, H.J. Lee, E.K. Wong, and B.I. Min New findings of the correlation between acupoints and corresponding brain cortices using functional MRI Proc Natl Acad Sci U S A 95 1998 2670 2673
15. E.M. Choi, F. Jiang, and J.C. Longhurst Point specificity in acupuncture Chin Med 7 2012 4
16. G. Deng, B.L. Hou, A.I. Holodny, and B.R. Cassileth Functional magnetic resonance imaging (fMRI) changes and saliva production associated with acupuncture at LI-2 acupuncture point: A randomized controlled study BMC Complement Altern Med 8 2008 37
17. R.P. Dhond, N. Kettner, and V. Napadow Neuroimaging acupuncture effects in the human brain J Altern Complement Med 13 2007 603 616
18. E.G. Duerden, and M.C. Albanese Localization of pain-related brain activation: A meta-analysis of neuroimaging data Hum Brain Mapp 34 2013 109 149
19. S.B. Eickhoff, A.R. Laird, C. Grefkes, L.E. Wang, K. Zilles, and P.T. Fox Coordinate-based activation likelihood estimation meta-analysis of neuroimaging data: A random-effects approach based on empirical estimates of spatial uncertainty Hum Brain Mapp 30 2009 2907 2926
20. S.B. Eickhoff, K.E. Stephan, H. Mohlberg, C. Grefkes, G.R. Fink, K. Amunts, and K. Zilles A new SPM toolbox for combining probabilistic cytoarchitectonic maps and functional imaging data Neuroimage 25 2005 1325 1335
21. D.M. Eisenberg, R.B. Davis, S.L. Ettner, S. Appel, S. Wilkey, M. Van Rompay, and R.C. Kessler Trends in alternative medicine use in the United States, 1990-1997: Results of a follow-up national survey JAMA 280 1998 1569 1575
22. J.M. Engelmann, F. Versace, J.D. Robinson, J.A. Minnix, C.Y. Lam, Y. Cui, V.L. Brown, and P.M. Cinciripini Neural substrates of smoking cue reactivity: A meta-analysis of fMRI studies Neuroimage 60 2012 252 262
23. J. Fang, Z. Jin, Y. Wang, K. Li, J. Kong, E.E. Nixon, Y. Zeng, Y. Ren, H. Tong, P. Wang, and K.K. Hui The salient characteristics of the central effects of acupuncture needling: Limbic-paralimbic-neocortical network modulation Hum Brain Mapp 30 2009 1196 1206
24. P.T. Fox, and J.L. Lancaster Opinion: Mapping context and content: The BrainMap model Nat Rev Neurosci 3 2002 319 321
25. I.K. Gareus, M. Lacour, A.C. Schulte, and J. Hennig Is there a BOLD response of the visual cortex on stimulation of the vision-related acupoint GB 37? J Magn Reson Imaging 15 2002 227 232
26. J.S. Han, and Y.S. Ho Global trends and performances of acupuncture research Neurosci Biobehav Rev 35 2011 680 687
27. K.K. Hui, J. Liu, N. Makris, R.L. Gollub, A.J. Chen, C.I. Moore, D.N. Kennedy, B.R. Rosen, and K.K. Kwong Acupuncture modulates the limbic system and subcortical gray structures of the human brain: Evidence from fMRI studies in normal subjects Hum Brain Mapp 9 2000 13 25
28. K.K. Hui, J. Liu, O. Marina, V. Napadow, C. Haselgrove, K.K. Kwong, D.N. Kennedy, and N. Makris The integrated response of the human cerebro-cerebellar and limbic systems to acupuncture stimulation at ST 36 as evidenced by fMRI Neuroimage 27 2005 479 496
29. K.K. Hui, O. Marina, J.D. Claunch, E.E. Nixon, J. Fang, J. Liu, M. Li, V. Napadow, M. Vangel, N. Makris, S.T. Chan, K.K. Kwong, and B.R. Rosen Acupuncture mobilizes the brain's default mode and its anti-correlated network in healthy subjects Brain Res 1287 2009 84 103
30. M. Ingvar Pain and functional imaging Philos Trans R Soc Lond B Biol Sci 354 1999 1347 1358
31. J. Kong, R.L. Gollub, J.M. Webb, J.T. Kong, M.G. Vangel, and K. Kwong Test-retest study of fMRI signal change evoked by electroacupuncture stimulation Neuroimage 34 2007 1171 1181
32. J. Kong, T.J. Kaptchuk, J.M. Webb, J.T. Kong, Y. Sasaki, G.R. Polich, M.G. Vangel, K. Kwong, B. Rosen, and R.L. Gollub Functional neuroanatomical investigation of vision-related acupuncture point specificity-a multisession fMRI study Hum Brain Mapp 30 2009 38 46
33. J. Kong, M.L. Loggia, C. Zyloney, P. Tu, P. Laviolette, and R.L. Gollub Exploring the brain in pain: Activations, deactivations and their relation Pain 148 2010 257 267
34. J. Kong, L. Ma, R.L. Gollub, J. Wei, X. Yang, D. Li, X. Weng, F. Jia, C. Wang, F. Li, R. Li, and D. Zhuang A pilot study of functional magnetic resonance imaging of the brain during manual and electroacupuncture stimulation of acupuncture point (LI-4 Hegu) in normal subjects reveals differential brain activation between methods J Altern Complement Med 8 2002 411 419
35. A.R. Laird, J.L. Lancaster, and P.T. Fox BrainMap: The social evolution of a human brain mapping database Neuroinformatics 3 2005 65 78
36. J.L. Lancaster, D. Tordesillas-Gutierrez, M. Martinez, F. Salinas, A. Evans, K. Zilles, J.C. Mazziotta, and P.T. Fox Bias between MNI and Talairach coordinates analyzed using the ICBM-152 brain template Hum Brain Mapp 28 2007 1194 1205
37. H.M. Langevin, P.M. Wayne, H. Macpherson, R. Schnyer, R.M. Milley, V. Napadow, L. Lao, J. Park, R.E. Harris, M. Cohen, K.J. Sherman, A. Haramati, and R. Hammerschlag Paradoxes in acupuncture research: Strategies for moving forward Evid Based Complement Alternat Med 2011 10.1155/2011/180805
38. G.T. Lewith, P.J. White, and J. Pariente Investigating acupuncture using brain imaging techniques: The current state of play Evid Based Complement Alternat Med 2 2005 315 319
39. G. Li, R.T. Cheung, Q.Y. Ma, and E.S. Yang Visual cortical activations on fMRI upon stimulation of the vision-implicated acupoints Neuroreport 14 2003 669 673
40. G. Li, L. Huang, R.T. Cheung, S.R. Liu, Q.Y. Ma, and E.S. Yang Cortical activations upon stimulation of the sensorimotor-implicated acupoints Magn Reson Imaging 22 2004 639 644
41. G. Li, H.L. Liu, R.T. Cheung, Y.C. Hung, K.K. Wong, G.G. Shen, Q.Y. Ma, and E.S. Yang An fMRI study comparing brain activation between word generation and electrical stimulation of language-implicated acupoints Hum Brain Mapp 18 2003 233 238
42. F. Lui, D. Duzzi, M. Corradini, M. Serafini, P. Baraldi, and C.A. Porro Touch or pain? Spatio-temporal patterns of cortical fMRI activity following brief mechanical stimuli Pain 138 2008 362 374
43. I. Lund, and T. Lundeberg Are minimal, superficial or sham acupuncture procedures acceptable as inert placebo controls? Acupunct Med 24 2006 13 15
44. D. Mantini, M. Caulo, A. Ferretti, G.L. Romani, and A. Tartaro Noxious somatosensory stimulation affects the default mode of brain function: Evidence from functional MR imaging Radiology 253 2009 797 804
45. R. Melzack, and P.D. Wall Pain mechanisms: A new theory Science 150 1965 971 979
46. B.J. Na, G.H. Jahng, S.U. Park, W.S. Jung, S.K. Moon, J.M. Park, and H.S. Bae An fMRI study of neuronal specificity of an acupoint: Electroacupuncture stimulation of Yanglingquan (GB34) and its sham point Neurosci Lett 464 2009 1 5
47. A. Nakagoshi, M. Fukunaga, M. Umeda, Y. Mori, T. Higuchi, and C. Tanaka Somatotopic representation of acupoints in human primary somatosensory cortex: An FMRI study Magn Reson Med Sci 4 2005 187 189
48. V. Napadow, N. Makris, J. Liu, N.W. Kettner, K.K. Kwong, and K.K. Hui Effects of electroacupuncture versus manual acupuncture on the human brain as measured by fMRI Hum Brain Mapp 24 2005 193 205
49. V. Napadow, R.P. Dhond, J. Kim, L. LaCount, M. Vangel, R.E. Harris, N. Kettner, and K. Park Brain encoding of acupuncture sensation-coupling on-line rating with fMRI Neuroimage 47 2009 1055 1065
50. R. Peyron, B. Laurent, and L. Garcia-Larrea Functional imaging of brain responses to pain. A review and meta-analysis Neurophysiol Clin 30 2000 263 288
51. M.E. Raichle, A.M. MacLeod, A.Z. Snyder, W.J. Powers, D.A. Gusnard, and G.L. Shulman A default mode of brain function Proc Natl Acad Sci U S A 98 2001 676 682
52. J. Schliessbach, E. van der Klift, A. Siegenthaler, L. Arendt-Nielsen, M. Curatolo, and K. Streitberger Does acupuncture needling induce analgesic effects comparable to diffuse noxious inhibitory controls? Evid Based Complement Alternat Med 2012 10.1155/2012/785613
53. C.M. Siedentopf, S.M. Golaszewski, F.M. Mottaghy, C.C. Ruff, S. Felber, and A. Schlager Functional magnetic resonance imaging detects activation of the visual association cortex during laser acupuncture of the foot in humans Neurosci Lett 327 2002 53 56
54. A.L.S.C. Tjen, P. Li, and J.C. Longhurst Medullary substrate and differential cardiovascular responses during stimulation of specific acupoints Am J Physiol Regul Integr Comp Physiol 287 2004 R852 R862
55. R.D. Treede, D.R. Kenshalo, R.H. Gracely, and A.K. Jones The cortical representation of pain Pain 79 1999 105 111
56. G.A. Ulett, S. Han, and J.S. Han Electroacupuncture: Mechanisms and clinical application Biol Psychiatry 44 1998 129 138
57. J. Vas, C. Ortega, V. Olmo, F. Perez-Fernandez, L. Hernandez, I. Medina, J.M. Seminario, A. Herrera, F. Luna, E. Perea-Milla, C. Mendez, F. Madrazo, C. Jimenez, M.A. Ruiz, and I. Aguilar Single-point acupuncture and physiotherapy for the treatment of painful shoulder: A multicentre randomized controlled trial Rheumatology (Oxford) 47 2008 887 893
58. T. Wesolowski, M. Lotze, M. Domin, S. Langner, C. Lehmann, M. Wendt, and T.I. Usichenko Acupuncture reveals no specific effect on primary auditory cortex: A functional magnetic resonance imaging study Neuroreport 20 2009 116 120
59. A. White, N.E. Foster, M. Cummings, and P. Barlas Acupuncture treatment for chronic knee pain: A systematic review Rheumatology (Oxford) 46 2007 384 390
60. WHO Acupuncture: Review and Analysis of Reports on Controlled Clinical Trials 2002 World Health Organization
61. M.T. Wu, J.C. Hsieh, J. Xiong, C.F. Yang, H.B. Pan, Y.C. Chen, G. Tsai, B.R. Rosen, and K.K. Kwong Central nervous pathway for acupuncture stimulation: Localization of processing with functional MR imaging of the brain-preliminary experience Radiology 212 1999 133 141
62. M.T. Wu, J.M. Sheen, K.H. Chuang, P. Yang, S.L. Chin, C.Y. Tsai, C.J. Chen, J.R. Liao, P.H. Lai, K.A. Chu, H.B. Pan, and C.F. Yang Neuronal specificity of acupuncture response: A fMRI study with electroacupuncture Neuroimage 16 2002 1028 1037
63. S.S. Yoo, E.K. Teh, R.A. Blinder, and F.A. Jolesz Modulation of cerebellar activities by acupuncture stimulation: Evidence from fMRI study Neuroimage 22 2004 932 940
64. W.T. Zhang, Z. Jin, F. Luo, L. Zhang, Y.W. Zeng, and J.S. Han Evidence from brain imaging with fMRI supporting functional specificity of acupoints in humans Neurosci Lett 354 2004 50 53