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Volumn 21, Issue 7, 2013, Pages 1775-1786
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Probing functional diversity in pactamycin toward antibiotic, antitumor, and antiprotozoal activity
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Author keywords
Analogs; Aniline; Antibacterial; Anticancer; Antiprotozoal; Pactamycin; Urea
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Indexed keywords
5 AMINO 2,3 DIHYDROXY 1 (1 HYDROXYETHYL) 3 (HYDROXYETHYL) 4 [(3 HYDROXYMETHYL)AMINO] 2 METHYLCYCLOPENTYL 1,1 DIMETHYLUREA;
5 AMINO 2,3 DIHYDROXY 1 (1 HYDROXYETHYL) 3 (HYDROXYMETHYL) 2 METHYL 4 (PHENYLAMINO)CYCLOPENTYL 1,1 DIMETHYLUREA;
5 AMINO 2,3 DIHYDROXY 1 (1 HYDROXYETHYL) 3 (HYDROXYMETHYL) 4 [(3 METHOXYPHENYL)AMINO] 2 METHYLCYCLOPENTYL 1,1 DIMETHYLUREA;
5 AMINO 4 [(3 FLUOROPHENYL)AMINO] 2,3 DIHYDROXY 1 (1 HYDROXYETHYL) 3 (HYDROXYMETHYL) 2 METHYLCYCLOPENTYL 1,1 DIMETHYLUREA;
[4 [(3 ACETYLPHENYL)AMINO] 5 AMINO 2,3 DIHYDROXY 1 (1 HYDROXYETHYL) 3 (HYDROXYMETHYL) 2 METHYLCYCLOPENTYL] 1,1 DIETHYLUREA;
[4 [(3 ACETYLPHENYL)AMINO] 5 AMINO 2,3 DIHYDROXY 1 (1 HYDROXYETHYL) 3 (HYDROXYMETHYL) 2 METHYLCYCLOPENTYL]MORPHOLINE 4 CARBOXAMIDE;
[4 [(3 ACETYLPHENYL)AMINO] 5 AMINO 2,3 DIHYDROXY 1 (1 HYDROXYETHYL) 3 (HYDROXYMETHYL) 2 METHYLCYCLOPENTYL]PIPERIDINE 1 CARBOXAMIDE;
[4 [(3 ACETYLPHENYL)AMINO] 5 AMINO 2,3 DIHYDROXY 1 (1 HYDROXYETHYL) 3 (HYDROXYMETHYL) 2 METHYLCYCLOPENTYL]PYRROLIDINE 1 CARBOXAMIDE;
[5 AMINO 2,3 DIHYDROXY 1 (1 HYDROXYETHYL) 3 (HYDROXYMETHYL) 3 (HYDROXYMETHYL) 2 METHYL 4 [[3 (TRIFLUOROMETHYL)PHENYL]AMINO]CYCLOPENTYL] 1,1 DIMETHYLUREA;
ANTIINFECTIVE AGENT;
ANTINEOPLASTIC AGENT;
ANTIPROTOZOAL AGENT;
DE 6 METHYLSALICYLYL PACTAMYCATE;
DE 6 METHYLSALICYLYL PACTAMYCIN;
PACTAMYCATE;
PACTAMYCIN;
UNCLASSIFIED DRUG;
ACINETOBACTER BAUMANNII;
ANTIBACTERIAL ACTIVITY;
ANTIMALARIAL ACTIVITY;
ANTINEOPLASTIC ACTIVITY;
ANTIPROTOZOAL ACTIVITY;
ARTICLE;
CELL STRAIN HCT116;
CHEMICAL MODIFICATION;
DRUG CYTOTOXICITY;
DRUG SCREENING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ENTEROCOCCUS FAECALIS;
ESCHERICHIA COLI;
IC 50;
IN VITRO STUDY;
KLEBSIELLA PNEUMONIAE;
MINIMUM INHIBITORY CONCENTRATION;
NONHUMAN;
PHYSICAL CHEMISTRY;
PLASMODIUM FALCIPARUM;
PSEUDOMONAS AERUGINOSA;
STAPHYLOCOCCUS AUREUS;
STRUCTURE ACTIVITY RELATION;
ANTI-BACTERIAL AGENTS;
ANTINEOPLASTIC AGENTS;
ANTIPROTOZOAL AGENTS;
BACTERIA;
BACTERIAL INFECTIONS;
CELL LINE, TUMOR;
HUMANS;
MALARIA, FALCIPARUM;
NEOPLASMS;
PACTAMYCIN;
PLASMODIUM FALCIPARUM;
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EID: 84875225020
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2013.01.037 Document Type: Article |
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Times cited : (29)
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References (35)
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