Caveolin-1 up-regulates integrin α2,6-sialylation to promote integrin α5β1-dependent hepatocarcinoma cell adhesion

FEBS Letters

Volumn 587, Issue 6, 2013, Pages 782-787

  Yu, Shengjin ^a,b   Fan, Jianhui ^a   Liu, Linhua ^a   Zhang, Lijun ^a   Wang, Shujing ^a   Zhang, Jianing ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b EASTERN LIAONING UNIVERSITY   (China)

Author keywords

2,6 Sialylation; Caveolin 1; Extracellular matrix; Integrin

Indexed keywords

ALPHA INTEGRIN; CAVEOLIN 1; FIBRONECTIN; FOCAL ADHESION KINASE; INTEGRIN ALPHA2,6; SIALIC ACID; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 5;

ANIMAL CELL; ARTICLE; CARCINOMA CELL; CELL ADHESION; CELL SURFACE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; LIVER CELL CARCINOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIALYLATION; UPREGULATION;

ANIMALS; CARCINOMA, HEPATOCELLULAR; CAVEOLIN 1; CELL ADHESION; CELL LINE, TUMOR; FIBRONECTINS; FOCAL ADHESION KINASE 1; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, REPORTER; GLYCOSYLATION; INTEGRIN ALPHA2; INTEGRIN ALPHA5BETA1; INTEGRIN ALPHA6; LIVER NEOPLASMS; LUCIFERASES; MICE; PHOSPHORYLATION; SIALIC ACIDS; SIALYLTRANSFERASES; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 84875221360     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.02.002     Document Type: Article

References (31)

1. J.A. Joyce, and J.W. Pollard Microenvironmental regulation of metastasis Nat. Rev. Cancer 9 2009 239 252
2. G. von Wichert, and M.P. Sheetz Mechanisms of disease: the biophysical interpretation of the ECM affects physiological and pathophysiological cellular behavior Z. Gastroenterol. 43 2005 1329 1336
3. R.O. Hynes Integrins: bidirectional, allosteric signaling machines Cell 110 2002 673 687
4. J. Gu, T. Isaji, Y. Sato, Y. Kariya, and T. Fukuda Importance of N-glycosylation on alpha5beta1 integrin for its biological functions Biol. Pharm. Bull. 32 2009 780 785
5. B. Razani, and M.P. Lisanti Caveolin-deficient mice: insights into caveolar function human disease J. Clin. Invest. 108 2001 1553 1561
6. M. Cokakli, E. Erdal, D. Nart, F. Yilmaz, O. Sagol, M. Kilic, S. Karademir, and N. Atabey Differential expression of Caveolin-1 in hepatocellular carcinoma: correlation with differentiation state, motility and invasion BMC Cancer 9 2009 65 76
7. Y. Tang, X. Zeng, F. He, Y. Liao, N. Qian, and M. Toi Caveolin-1 is related to invasion, survival, and poor prognosis in hepatocellular cancer Med. Oncol. 29 2012 977 984
8. S. Wang, L. Jia, H. Zhou, X. Wang, and J. Zhang Caveolin-1 promotes the transformation and anti-apoptotic ability of mouse hepatoma cells IUBMB Life 60 2008 693 699
9. H. Zhou, L. Jia, S. Wang, H. Wang, H. Chu, Y. Hu, J. Cao, and J. Zhang Divergent expression and roles for caveolin-1 in mouse hepatocarcinoma cell lines with varying invasive ability Biochem. Biophys. Res. Commun. 345 2006 486 494
10. K. Sasai, Y. Ikeda, H. Ihara, K. Honke, and N. Taniguchi Caveolin-1 regulates the functional localization of N-acetylglucosaminyltransferase III within the golgi apparatus J. Biol. Chem. 278 2003 25295 25301
11. P.H. Wang, W.L. Lee, Y.R. Lee, C.M. Juang, Y.J. Chen, H.T. Chao, Y.C. Tsai, and C.C. Yuan Enhanced expression of alpha 2,6-sialyltransferase ST6Gal I in cervical squamous cell carcinoma Gynecol. Oncol. 89 2003 395 401
12. Y. Kaneko, H. Yamamoto, D.S. Kersey, K.J. Colley, J.E. Leestma, and J.R. Moskal The expression of Gal beta 1,4GlcNAc alpha 2,6 sialyltransferase and alpha 2,6-linked sialoglycoconjugates in human brain tumors Acta Neuropathol. 91 1996 284 292
13. F. Dall'Olio, M. Chiricolo, A. D'Errico, E. Gruppioni, A. Altimari, M. Fiorentino, and W.F. Grigioni Expression of beta-galactoside alpha2,6 sialyltransferase and of alpha2,6-sialylated glycoconjugates in normal human liver, hepatocarcinoma, and cirrhosis Glycobiology 14 2004 39 49
14. S. Yu, L. Zhang, N. Li, J. Fan, L. Liu, J. Zhang, and S. Wang Caveolin-1 up-regulates ST6Gal-I to promote the adhesive capability of mouse hepatocarcinoma cells to fibronectin via FAK-mediated adhesion signaling Biochem. Biophys. Res. Commun. 427 2012 506 512
15. B. Leitinger, A. McDowall, P. Stanley, and N. Hogg The regulation of integrin function by Ca(2+) Biochim. Biophys. Acta 1498 2000 91 98
16. Q. Chen, L.H. Meng, C.H. Zhu, L.P. Lin, H. Lu, and J. Ding ADAM15 suppresses cell motility by driving integrin alpha5beta1 cell surface expression via Erk inactivation Int. J. Biochem. Cell Biol. 40 2008 2164 2173
17. M.D. Schaller FAK and paxillin: regulators of N-cadherin adhesion and inhibitors of cell migration? J. Cell Biol. 166 2004 157 159
18. J.W. Dennis, M. Granovsky, and C.E. Warren Protein glycosylation in development and disease Bioessays 21 1999 412 421
19. C. Glait, D. Ravid, S.W. Lee, M. Liscovitch, and H. Werner Caveolin-1 controls BRCA1 gene expression and cellular localization in human breast cancer cells FEBS Lett. 580 2006 5268 5274
20. P.K. Sengupta, M.P. Bouchie, and M.A. Kukuruzinska N-glycosylation gene DPAGT1 is a target of the Wnt/beta-catenin signaling pathway J. Biol. Chem. 285 2010 31164 31173
21. H. Yamamoto, H. Komekado, and A. Kikuchi Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin Dev. Cell 11 2006 213 223
22. L. Jia, S. Wang, H. Zhou, J. Cao, Y. Hu, and J. Zhang Caveolin-1 up-regulates CD147 glycosylation and the invasive capability of murine hepatocarcinoma cell lines Int. J. Biochem. Cell Biol. 38 2006 1584 1593
23. E. Arpaia The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk Oncogene 31 2012 884 896
24. M. Dalziel, F. Dall'Olio, A. Mungul, V. Piller, and F. Piller Ras oncogene induces beta-galactoside alpha2,6-sialyltransferase (ST6Gal I) via a RalGEF-mediated signal to its housekeeping promoter Eur. J. Biochem. 271 2004 3623 3634
25. K. Kato Overexpression of caveolin-1 in esophageal squamous cell carcinoma correlates with lymph node metastasis and pathologic stage Cancer 94 2002 929 933
26. P.H. Rajjayabun, S. Garg, G.C. Durkan, R. Charlton, M.C. Robinson, and J.K. Mellon Caveolin-1 expression is associated with high-grade bladder cancer Urology 58 2001 811 814
27. S.W. Fine, M.P. Lisanti, F. Galbiati, and M. Li Elevated expression of caveolin-1 in adenocarcinoma of the colon Am. J. Clin. Pathol. 115 2001 719 724
28. Z.B. Zhang, L. Cai, S.G. Zheng, Y. Xiong, and J.H. Dong Overexpression of caveolin-1 in hepatocellular carcinoma with metastasis and worse prognosis: correlation with vascular endothelial growth factor, microvessel density and unpaired artery Pathol. Oncol. Res. 15 2009 495 502
29. H.B. Guo, I. Lee, M. Kamar, S.K. Akiyama, and M. Pierce Aberrant N-glycosylation of beta1 integrin causes reduced alpha5beta1 integrin clustering and stimulates cell migration Cancer Res. 62 2002 6837 6845
30. D.R. Christie, F.M. Shaikh, J.A.t. Lucas, J.A. Lucas 3rd, and S.L. Bellis ST6Gal-I expression in ovarian cancer cells promotes an invasive phenotype by altering integrin glycosylation and function J. Ovarian Res. 1 2008 3 10
31. T. Isaji Introduction of bisecting GlcNAc into integrin alpha5beta1 reduces ligand binding and down-regulates cell adhesion and cell migration J. Biol. Chem. 279 2004 19747 19754