A randomised, double-blind, placebo-controlled phase 2 study of trebananib (AMG 386) in combination with FOLFIRI in patients with previously treated metastatic colorectal carcinoma

British Journal of Cancer

Volumn 108, Issue 3, 2013, Pages 503-511

  Peeters, M ^a   Strickland, A H ^b   Lichinitser, M ^c   Suresh, A V S ^d   Manikhas, G ^e   Shapiro, J ^f   Rogowski, W ^g   Huang, X ^h   Wu, B ^h   Warner, D ^h   Jain, R ^h   Tebbutt, N C ⁱ  

^a ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^b MONASH MEDICAL CENTRE   (Australia)

^c INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

^d Institute of Oncology and Regional Cancer Centre   (India)

^e ST PETERSBURG STATE UNIVERSITY   (Russian Federation)

^f CABRINI HOSPITAL   (Australia)

^g Olsztyn Cancer Center   (Poland)

^h AMGEN INC   (United States)

ⁱ NORTHERN HEALTH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN 1; ANGIOPOIETIN 2; ANGIOPOIETIN RECEPTOR; BEVACIZUMAB; FLUOROPYRIMIDINE; FLUOROURACIL; FOLINIC ACID; IRINOTECAN; OXALIPLATIN; PLACEBO; TREBANANIB;

ABDOMINAL PAIN; ADULT; ADVERSE OUTCOME; ALOPECIA; ANEMIA; ANOREXIA; ARTERIAL THROMBOEMBOLISM; ARTICLE; ASTHENIA; BLEEDING; CANCER COMBINATION CHEMOTHERAPY; CANCER SURVIVAL; COLON ADENOCARCINOMA; CONSTIPATION; CONTINUOUS INFUSION; CONTROLLED STUDY; COUGHING; DIARRHEA; DIGESTIVE SYSTEM PERFORATION; DISEASE COURSE; DRUG SAFETY; FATIGUE; FEMALE; FEVER; HUMAN; HYPERTENSION; HYPOKALEMIA; LEUKOPENIA; LUNG EDEMA; MAJOR CLINICAL STUDY; MALE; NAUSEA; NEUTROPENIA; OVERALL SURVIVAL; PERIPHERAL EDEMA; PHASE 2 CLINICAL TRIAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PROTEINURIA; RANDOMIZED CONTROLLED TRIAL; RECTUM CARCINOMA; STOMATITIS; TREATMENT OUTCOME; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT; VENOUS THROMBOEMBOLISM; VOMITING;

ADENOCARCINOMA; ADULT; AGED; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CAMPTOTHECIN; COLORECTAL NEOPLASMS; DOUBLE-BLIND METHOD; FEMALE; FLUOROURACIL; HUMANS; INTERNATIONAL AGENCIES; LEUCOVORIN; LIVER NEOPLASMS; MALE; MIDDLE AGED; PROGNOSIS; RECOMBINANT FUSION PROTEINS; SALVAGE THERAPY; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84875217930     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2012.594     Document Type: Article

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