Hydroxyapatite-coated poly(-caprolactone) microspheres fabricated via a Pickering emulsion route: Effect of fabrication parameters on diameter and chemical composition

Composite Interfaces

Volumn 20, Issue 1, 2013, Pages 45-56

  Fujii, Syuji ^a   Okada, Masahiro ^b   Nishimura, Taiki ^a   Sugimoto, Tatsuya ^a   Maeda, Hayata ^a   Hamasaki, Hiroyuki ^a   Furuzono, Tsutomu ^c   Nakamura, Yoshinobu ^a,d  

^a OSAKA INSTITUTE OF TECHNOLOGY   (Japan)

^b OSAKA DENTAL UNIVERSITY   (Japan)

^c KINKI UNIVERSITY   (Japan)

^d Nanomaterials Microdevices Research Center   (Japan)

Author keywords

Biodegradable; Emulsion; Microsphere; Polymer; Size control

Indexed keywords

BIODEGRADABLE; CHEMICAL COMPOSITIONS; EMULSION-SOLVENT EVAPORATION METHOD; FABRICATION PARAMETERS; HYDROXYAPATITE (HAP); PICKERING EMULSIONS; POLYMER MICROSPHERES; SIZE CONTROL;

BIODEGRADABLE POLYMERS; DIFFRACTION; DISPERSIONS; EMULSIFICATION; EMULSIONS; EVAPORATION; FABRICATION; HYDROXYAPATITE; NANOPARTICLES; OPTICAL DATA STORAGE; OPTICAL MICROSCOPY; PARTICLE SIZE ANALYSIS; PHASE TRANSITIONS; PLASTIC COATINGS; POLYMERS; SCANNING ELECTRON MICROSCOPY; TISSUE ENGINEERING;

MICROSPHERES;

EID: 84875203742     PISSN: 09276440     EISSN: 15685543     Source Type: Journal    
DOI: 10.1080/15685543.2013.762893     Document Type: Article

References (33)

1. (a) Bourgeat-Lami E. Organic-inorganic nanostructured colloids. J. Nanosci. Nanotechnol. 2002;2:1-24. (Pubitemid 135713374)
2. Balmer JA, Schmid A, Armes SP. Colloidal nanocomposite particles: quo vadis? J. Mater. Chem. 2008;18:5722-5730.
3. Zou H, Wu SS, Shen J. Polymer/silica nanocomposites: preparation, characterization, properties, and applications. Chem. Rev. 2008;108:3893-3957.
4. (a) Jongpaiboonkit L, Franklin-Ford T, Murphy WL. Growth of hydroxyapatite coatings on biodegradable polymer microspheres. ACS Appl. Mater. Interfaces 2009;1:1504-1511.
5. Cushnie EK, Khan YM, Laurencin CT. Amorphous hydroxyapatite-sintered polymeric scaffolds for bone tissue regeneration: physical characterization studies. J. Biomed. Mater. Res., Part A. 2008;84A:54-62. (Pubitemid 350244246)
6. (a) Bett JAS, Christner LG, Hall WK. Studies of the hydrogen held by solid. X11. Hydroxyapatite catalysts. J. Am. Chem. Soc. 1967;89:5535-5541.
7. Brown PE, Constanz B. Hydroxyapatite and related materials. London: CRC Press; 1994.
8. Aoki H. Science and medical application of hydroxyapatite. Tokyo: Ishiyaku Euro America; 1994.
9. Kohn J, Abramson S, Langer R. Bioresorbable and bioerodible materials., In: Ratner D, Hoffman AS, Schoen FJ, Lemons JE, editors. Biomaterials science: an introduction to materials in medicine. 2nd ed. San Diego (CA): Elsevier Academic Press; 2004. 115-27.
10. Qiu X, Han Y, Zhuang X, Chen X, Li Y, Jing X. Preparation of nano-hydroxyapatite/poly(L-lac-tide) biocomposite microspheres. J. Nanopart. Res. 2007;9:901-908.
11. (a) Kang S-W, Yang HS, Seo S-W, Han DK, Kim B-S. Apatite-coated poly(lactic-co-glycolic acid) microspheres as an injectable scaffold for bone tissue engineering. J. Biomed. Mater. Res., Part A. 2008;85A:747-756. (Pubitemid 351632888)
12. (b) Mima Y, Fukumoto S, Koyama H, Okada M, Tanaka S, Shoji T, Emoto M, Furuzono T, Nishizawa Y, Inaba M. Enhancement of cell-based therapeutic angiogenesis using a novel type of injectable scaffolds of hydroxyapatite- polymer nanocomposite microspheres. PLoS ONE. 2012;7:e35199.
13. Lv Q, Nair L, Laurencin CT. Fabrication, characterization, and in vitro evaluation of poly(lactic acid glycolic acid)/nano-hydroxyapatite composite microsphere-based scaffolds for bone tissue engineering in rotating bioreactors. J. Biomed. Mater. Res., Part A. 2009;91A:679-691.
14. Wong J, Brugger A, Khare A, Chaubal M, Papadopoulos P, Rabinow B, Kipp J, Ning J. Suspensions for intravenous (IV) injection: a review of development, preclinical and clinical aspects. Adv. Drug Delivery. Rev. 2008;60:939-954.
15. Nagata F, Miyajima T, Yokogawa Y. Surfactant-free preparation of poly(lactic acid)/hydroxyapatite microspheres. Chem. Lett. 2003;32:784-785. (Pubitemid 37542537)
16. (a) Fujii S, Okada M, Sawa H, Furuzono T, Nakamura Y. Hydroxyapatite nanoparticles as particu-late emulsifier: fabrication of hydroxyapatite-coated biodegradable microspheres. Langmuir. 2009;25:9759-9766.
17. (b) Maeda H, Okada M, Fujii S, Nakamura Y, Furuzono T. Hydroxyapatite nanoparticles as particulate emulsifier: preparation of multiple emulsion and multihollow micro-sphere. Langmuir. 2010;25:13727-13731.
18. (c) Liu X, Okada M, Maeda H, Fujii S, Furuzono T. Hydroxyapatite/ biodegradable poly-(L-lactide-co-caprolactone) composite microparticles as injectable scaffold by a Pickering emulsion route. Acta Biomater. 2011;7:821-828.
19. (d) Fujii S, Okada M, Nishimura T, Sugimoto T, Maeda H, Hamasaki H, Furuzono T, Nakamura Y. Hydroxy-apatite-armored poly(-caprolactone) microspheres and hydroxyapatite microcapsules fabricated via Pickering emulsion route. J. Colloid Interface Sci. 2012;374:1-8.
20. (e) Iwamoto T, Terada T, Kogai Y, Okada M, Fujii S, Furuzono T. Development of microspheres covered with hydroxyapatite nanocrystals as cell scaffold for angiogenesis. Funct. Mater. Lett. 2012;5:1260010-1-1260010-6
21. (f) Okada M, Fujii S, Nishimura T, Nakamura Y, Furuzono T. Solvent-free formation of hydroxyapa-tite coated biodegradable particles via nanoparticle-stabilized emulsion route. Appl. Surf. Sci. 2012;262:39-44.
22. (g) Fujii S, Miyanari Y, Nishimura T, Yokoyama Y, Hamasaki S, Okada M, Furuzono T, Matsuda S, Takamori H, Nakamura Y. In vitro degradation of hydroxyapatite nanopar-ticle-coated biodegradable microspheres. Polym. Degrad. Stab. 2013;98:377-386.
23. (a) Dordunoo SK, Jackson JK, Arsenault LA, Oktaba AM, Hunter WL, Burt HM. Taxol encapsulation in poly(epsilon-caprolactone) microspheres. Cancer Chemother. Pharmacol. 1995;36:279-282.
24. (b) Mukerjee A, Sinha VR, Pruthi V. Preparation and characterization of poly-caprolactone particles for controlled insulin delivery. J. Biomed. Pharm. Eng. 2007;1:40-44.
25. (a) Hench LL, Polak JM. Third-generation biomedical materials. Science 2002;295:1014-1017.
26. (b) Tsuji H, Ishizaka T. Porous biodegradable polyesters. II. Physical properties, morphology, and enzymatic and alkaline hydrolysis of porous poly(-caprolactone) films. J. Appl. Polym. Sci. 2001;80:2281-2291. (Pubitemid 32372055)
27. (c) Ang KC, Leong KF, Chua CK, Chandrasekaran M. Compressive properties and degradability of poly(-caprolatone)/hydroxyapatite composites under accelerated hydrolytic degradation. J. Biomed. Mater. Res. 2007;80A:655-660. (Pubitemid 46239077)
28. Fujii S, Okada M, Furuzono T. Hydroxyapatite nanoparticles as stimulus-responsive particulate emulsifiers. J. Colloid Interface Sci. 2007;315:287-296.
29. Okada M, Maeda H, Fujii S, Nakamura Y, Furuzono T. Formation of Pickering emulsions stabilized via interaction between nanoparticles dispersed in aqueous phase and polymer end groups dissolved in oil phase. Langmuir. 2012;28:9405-9412.
30. (a) Vignati E, Piazza R, Lockhart TP. Pickering emulsions: interfacial tension, colloidal layer morphology, and trapped-particle motion. Langmuir. 2003;19:6650-6656.
31. (b) Tarimala S, Dai LL. Structure of microparticles in solid-stabilized emulsions. Langmuir. 2004;20:3492-3494.
32. Ha C-S, Gardella JA. Surface chemistry of biodegradable polymers for drug delivery systems. Chem. Rev. 2005;105:4205-4232. (Pubitemid 41724071)
33. Kostarelos K. Rational design and engineering of delivery systems for therapeutics: biomedical exercises in colloid and surface science. Adv. Colloid Interface Sci. 2003;106:147-168.