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Volumn 25, Issue 17, 2009, Pages 9759-9766

Hydroxyapatite nanoparticles as particulate emulsifier: fabrication of hydroxyapatite-coated biodegradable microspheres

Author keywords

[No Author keywords available]

Indexed keywords

ACID GROUPS; CROSS SECTION; HAP NANOPARTICLE; OIL PHASE; OIL-IN-WATER EMULSIONS; PLLA; PLLA MICROSPHERES; POLY L LACTIC ACID; ULTRA-THIN; WATER INTERFACE;

EID: 69949158900     PISSN: 07437463     EISSN: None     Source Type: Journal    
DOI: 10.1021/la901100z     Document Type: Article
Times cited : (101)

References (72)
  • 30
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    • (a) Grandfils, C.; Flandroy, P.; Nihant, N.; Barbette, S.; Jérome, R.; Teyssié, P.; Thibaut, A. J. Biomed. Mater. Res. 1992, 26, 467.
    • (1992) J. Biomed. Mater. Res. , vol.26 , pp. 467
  • 42
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    • French Patent No. 2484281
    • (b) Fong, J. W. French Patent No. 2484281, 1981.
    • (1981)
    • Fong, J.W.1
  • 46
    • 69949178136 scopus 로고    scopus 로고
    • The shaking time, although arbitrary, was found to give reasonably reproducible emulsions
    • The shaking time, although arbitrary, was found to give reasonably reproducible emulsions.
  • 47
    • 0002855778 scopus 로고
    • Surface chemical characteristics and adsorption properties of apatite
    • Misra, D. N, Ed.; Plenum Press: New York
    • (a) Somasundaran, P.; Wang, Y. H. C. Surface chemical characteristics and adsorption properties of apatite. In Adsorption on and Surface Chemistry of Hydroxyapatite; Misra, D. N, Ed.; Plenum Press: New York, 1984; pp 129-149.
    • (1984) Adsorption on and Surface Chemistry of Hydroxyapatite , pp. 129-149
    • Somasundaran, P.1    Wang, Y.H.C.2
  • 58
    • 69949177307 scopus 로고    scopus 로고
    • ICH Harmonised Tripartite Guideline. Impurities: Guideline For Residual Solvents Q3C(R4). Current Step 4 version dated February 2009
    • ICH Harmonised Tripartite Guideline. Impurities: Guideline For Residual Solvents Q3C(R4). Current Step 4 version dated February 2009.
  • 59
    • 69949126671 scopus 로고    scopus 로고
    • In Figure 6c, the dark patches were observed inside of the microspheres. This weak dark contrast should not be due to the HAp component, which gives stronger dark contrast (see the strong dark contrast of the HAp surface layer in Figure 6c and d). This weak dark contrast should be due to the difference of sample thickness, which should be generated by electron damaging during the TEM observation and by ultrathin cross section sample preparation by microtoming. The HAp nanoparticles were only located on the PLLA microsphere surfaces at any HAp and PLLA ratio.
    • In Figure 6c, the dark patches were observed inside of the microspheres. This weak dark contrast should not be due to the HAp component, which gives stronger dark contrast (see the strong dark contrast of the HAp surface layer in Figure 6c and d). This weak dark contrast should be due to the difference of sample thickness, which should be generated by electron damaging during the TEM observation and by ultrathin cross section sample preparation by microtoming. The HAp nanoparticles were only located on the PLLA microsphere surfaces at any HAp and PLLA ratio.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.