Albuminuria: All you need to predict outcomes in chronic kidney disease?

Current Opinion in Nephrology and Hypertension

Volumn 19, Issue 6, 2010, Pages 513-518

  Gansevoort, Ron T ^a   Nauta, Ferdau L ^a   Bakker, Stephan J L ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

albuminuria; cardiovascular disease; chronic kidney disease; dipstick; eGFR; end stage renal disease; proteinuria; tubular protein transport

Indexed keywords

ALBUMIN;

ALBUMINURIA; CARDIOVASCULAR DISEASE; CHRONIC KIDNEY DISEASE; DIABETES MELLITUS; GLOMERULAR DYSFUNCTION; GLOMERULUS FILTRATION RATE; HUMAN; HYPERTENSION; MICROALBUMINURIA; PRIORITY JOURNAL; PROGNOSIS; REVIEW;

ALBUMINURIA; CARDIOVASCULAR DISEASES; CHRONIC DISEASE; GLOMERULAR FILTRATION RATE; HUMANS; KIDNEY DISEASES; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RISK ASSESSMENT; RISK FACTORS;

EID: 78049254903     PISSN: 10624821     EISSN: None     Source Type: Journal    
DOI: 10.1097/MNH.0b013e32833e4ce1     Document Type: Review

References (47)

1. Weiner DE, Tighiouart H, Amin MG, et al. Chronic kidney disease as a risk factor for cardiovascular disease and all-cause mortality: a pooled analysis of community-based studies. J Am Soc Nephrol 2004; 15:1307-1315.
2. Shlipak MG, Simon JA, Grady D, et al., Heart and Estrogen/progestin Replacement Study (HERS) Investigators. Renal insufficiency and cardiovascular events in postmenopausal women with coronary heart disease. J Am Coll Cardiol 2001; 38:705-711.
3. Shlipak MG, Heidenreich PA, Noguchi H, et al. Association of renal insufficiency with treatment and outcomes after myocardial infarction in elderly patients. Ann Intern Med 2002; 137:555-562.
4. Shlipak MG, Sarnak MJ, Katz R, et al. Cystatin C and the risk of death and cardiovascular events among elderly persons. N Engl J Med 2005; 352:2049-2060.
5. Shlipak MG, Fried LF, Cushman M, et al. Cardiovascular mortality risk in chronic kidney disease: comparison of traditional and novel risk factors. JAMA 2005; 293:1737-1745.
6. Go AS, Chertow GM, Fan D, et al. Chronic kidney disease and the risks of death, cardiovascular events, and hospitalization. N Engl J Med 2004; 351:1296-1305.
7. Muntner P, He J, Hamm L, et al. Renal insufficiency and subsequent death resulting from cardiovascular disease in the United States. J Am Soc Nephrol 2002; 13:745-753.
8. Garg AX, Clark WF, Haynes RB, House AA. Moderate renal insufficiency and the risk of cardiovascular mortality: results from the NHANES I. Kidney Int 2002; 61:1486-1494.
9. Culleton BF, Larson MG, Wilson PW, et al. Cardiovascular disease and mortality in a community-based cohort with mild renal insufficiency. Kidney Int 1999; 56:2214-2219.
10. Henry RM, Kostense PJ, Bos G, et al. Mild renal insufficiency is associated with increased cardiovascular mortality: the Hoorn Study. Kidney Int 2002; 62:1402-1407.
11. KurthT, de Jong PE, CookNR, et al. Kidney function and risk of cardiovascular disease and mortality in women: a prospective cohort study. BMJ 2009; 338:b2392.
12. Mogensen CE. Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes. N Engl J Med 1984; 310:356-360.
13. Wachtell K, Ibsen H, Olsen MH, et al. Albuminuria and cardiovascular risk in hypertensive patients with left ventricular hypertrophy: the LIFE study. Ann Intern Med 2003; 139:901-906.
14. Damsgaard EM, Frøland A, Jørgensen OD, Mogensen CE. Microalbuminuria as predictor of increased mortality in elderly people. BMJ 1990; 300:297-300.
15. Hillege HL, FidlerV, DiercksGF, et al., for the PREVEND Study Group. Urinary albumin excretion predicts cardiovascular and noncardiovascular mortality in general population. Circulation 2002; 106:1777-1782.
16. Perkovic V, Verdon C, NinomiyaT, et al. The relationship between proteinuria and coronary risk: a systematic review and meta-analysis. PLoS Med 2008; 5:1486-1495.
17. The Chronic Kidney Disease Prognosis Consortium, Matsushita K, van der Ruggenenti P, Perna A, Mosconi L, et al. Urinary protein excretion rate is the best independent predictor of ESRF in nondiabetic proteinuric chronic nephropathies. 'Gruppo Italiano di Studi Epidemiologici in Nefrologia' (GISEN). Kidney Int 1998; 53: 1209-1216.
18. Jafar TH, Stark PC, Schmid CH, et al., AIPRD Study Group. Progression of chronic kidney disease: the role of blood pressure control, proteinuria, and angiotensin-converting enzyme inhibition: a patient-level meta-analysis. Ann Intern Med 2003; 139:244-252.
19. Keane WF, Zhang Z, Lyle PA, et al., RENAAL Study Investigators. Risk scores for predicting outcomes in patients with type 2 diabetes and nephropathy: the RENAAL study. Clin J Am Soc Nephrol 2006; 1:761-767.
20. Iseki K, Kinjo K, Iseki C, Takishita S. Relationship between predicted creatinine clearance and proteinuria and the risk of developing ESRD in Okinawa, Japan. Am J Kidney Dis 2004; 44:806-814.
21. van der Velde M, Halbesma N, de Charro FT, et al. Screening for albuminuria identifies individuals at increased renal risk. J Am Soc Nephrol 2009; 20:852-862.
22. Hallan SI, Ritz E, Lydersen S, et al. Combining GFRand albuminuria to classify CKD improves prediction of ESRD. J Am Soc Nephrol 2009; 20:1069-1077.
23. Hemmelgarn BR, Manns BJ, Lloyd A, et al. Relation between kidney function, Verhave JC, Gansevoort RT, Hillege HL, et al., PREVEND Study Group. An elevated urinary albumin excretion predicts de novo development of renal function impairment in the general population. Kidney Int 2004; 92:S18-21.
24. Kshirsagar AV, Bang H, Bomback AS, et al. A simple algorithm to predict incident kidney disease. Arch Intern Med 2008; 168:2466-2473.
25. Halbesma N, Jansen DF, Heymans MW, et al. and Gansevoort RT for the PREVEND study group. Development and validation of a general population Renal Risk Score [abstract]. J Am Soc Nephrol 2009 [Epub ahead of print].
26. Bash LD, Coresh J, Kottgen A, et al. Defining incident chronic kidney disease The Chronic Kidney Disease Prognosis Consortium: association of estimated glomerular filtration rate and albuminuria with kidney outcomes: a collaborative meta-analysis of general and high risk population cohorts. Kidney Int (in press).
27. Bakker SJ, Gansevoort RT, Stuveling EM, et al. Microalbuminuria and C-reactive protein: similar messengers of cardiovascular risk? CurrHypertens Rep 2005; 7:379-384.
28. Deckert T, Feldt-Rasmussen B, Borch-Johnsen K, et al. Albuminuria reflects widespread vascular damage. The Steno hypothesis. Diabetologia 1989; 32:219-226.
29. Bakker SJ, Gansevoort RT, de Zeeuw D. Albuminuria: what can we expect from the determination of nonimmunoreactive albumin? Curr Hypertens Rep 2009; 11:111-117.
30. Dalla Vestra M, Saller A, Bortoloso E, et al. Structural involvement in type 1 and type 2 diabetic nephropathy. Diabetes Metab 2000; 26:S8-S14.
31. El Nahas M. Cardio-kidney-damage: a unifying concept. Kidney Int 2010; 78:14-18.
32. Nangaku M. Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure. J Am Soc Nephrol 2006; 17:17-25.
33. Cook NR, Ridker PM. Advances in measuring the effect of individual predictors of cardiovascular risk: the role of reclassification measures. Ann Intern Med 2009; 150:795-802.
34. Taal MW, Brenner BM. Renal risk scores: progress and prospects. Kidney Int 2008; 73:1216-1219.
35. Bang H, Mazumdar M, Newman G, et al. Screening for kidney disease in vascular patients: screening for Occult Renal Disease (SCORED) experience. Nephrol Dial Transplant 2009; 24:2452-2457.
36. Fine EJ, Blaufox MD. Prediction rule for renal artery stenosis. Ann Intern Med 1999; 131:227-228.
37. Wakai K, Kawamura T, Endoh M, et al. A scoring system to predict renal outcome in IgA nephropathy: from a nationwide prospective study. Nephrol Dial Transplant 2006; 21:2800-2808.
38. Bang H, Vupputuri S, Shoham DA, et al. Screening for Occult Renal Disease (SCORED): a simple prediction model for chronic kidney disease. Arch Intern Med 2007; 167:374-381.
39. Mackinnon B, Shakerdi L, Deighan CJ, et al. Urinary transferrin, high molecular weight proteinuria and the progression of renal disease. Clin Nephrol 2003; 59:252-258.
40. Reichert LJ, Koene RA, Wetzels JF. Urinary IgG excretion as a prognostic factor in idiopathic membranous nephropathy. Clin Nephrol 1997; 48:79-84.
41. Halimi JM, Matthias B, Al Najjar A, et al. Respective predictive role of urinary albumin excretion and nonalbumin proteinuria on graft loss and death in renal transplant recipients. Am J Transplant 2007; 7:2775-2781.
42. van der Velde M, de Jong PE, Gansevoort RT. Comparison of the yield of different screening approaches to detect chronic kidney disease. Nephrol Dial Transplant 2010; Mar 24 [Epub ahead of print].
43. Rigalleau V, LasseurC, Raffaitin C, et al. Normoalbuminuric renal-insufficient diabetic patients: a lower-risk group. Diabetes Care 2007; 30:2034-2039.
44. de Zeeuw D, Remuzzi G, Parving HH, et al. Albuminuria, a therapeutic target for cardiovascular protection in type 2 diabetic patients with nephropathy. Circulation 2004; 110:921-927.
45. Boersma C, Postma MJ, Visser ST, et al., PREVEND Study Group. Baseline albuminuria predicts the efficacy of blood pressure-lowering drugs in preventing cardiovascular events. Br J Clin Pharmacol 2008; 65:723-732.
46. Atthobari J, Asselbergs FW, Boersma C, et al., PREVEND IT Study Group. Cost-effectiveness of screening for albuminuria with subsequent fosinopril treatment to prevent cardiovascular events: a pharmacoeconomic analysis linked to the PREVEND study and the PREVEND IT trial. Clin Ther 2006; 28:432-444.
47. Boersma C, Gansevoort RT, Pechlivanoglou P, et al. for the PREVEND Study Group: cost-effectiveness of population-based 'Screen-and-Treat' strategies for albuminuria to prevent cardiovascular and renal disease. Clinical Therapeut 2010; 32:1103-1121.