A robust, streamlined approach to bosutinib monohydrate

Organic Process Research and Development

Volumn 17, Issue 3, 2013, Pages 500-504

  Withbroe, Gregory J ^a   Seadeek, Chris ^a   Girard, Kevin P ^a   Guinness, Steven M ^a   Vanderplas, Brian C ^a   Vaidyanathan, Rajappa ^a,b  

^a PFIZER INC   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEX SOLIDS; SOLID FORMS;

EID: 84875138493     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op300087r     Document Type: Article

References (7)

1. Sutherland, K. W.; Feigelson, G. B.; Boschelli, D. H.; Blum, D. M.; Strong, H. L. U. S. Patent 2005043537 A1, 2005
2. Boschelli, D. H.; Wang, Y. D.; Johnson, S.; Wu, B.; Ye, F.; Sosa, A. C. B.; Golas, J. M.; Boschelli, F. J. Med. Chem. 2004, 47, 1599
3. Boschelli, D. H.; Ye, F.; Wang, Y. D.; Dutia, M.; Johnson, S. L.; Wu, B.; Miller, K.; Powell, D. W.; Yaczko, D.; Young, M.; Tischler, M.; Arndt, K.; Discafani, C.; Etienne, C.; Gibbons, J.; Grod, J.; Lucas, J.; Weber, J. M.; Boschelli, F. J. Med. Chem. 2001, 44, 3965
4. Olszewski, J. D.; May, M. K.; Berger, D. M. U.S. Patent 20070208164A1, 2007
5. Feigelson, G.; Place, D.; Duan, S.; Hansen, E.; Pye, P.; Gontcharov, A.; Varsolona, R.; Tadayon, S.; Mirmehrabi, M.; Faqih, M.; Eberhardt, J.; Deshmukh, S.; Mills, R.; McWilliams, J. C. Unpublished results
6. Tesconi, M. S.; Feigelson, G.; Strong, H.; Wen, H. PCT Int. Appl. WO/2007/005462 A1 20070111, 2007
7. 3 and MIBK prior to an aqueous quench