Functional elements associated with hepatic regeneration in living donors after right hepatic lobectomy

Liver Transplantation

Volumn 19, Issue 3, 2013, Pages 292-304

  Everson, Gregory T ^a   Hoefs, John C ^b   Niemann, Claus U ^c   Olthoff, Kim M ^d   Dupuis, Robert ^e   Lauriski, Shannon ^a   Herman, Andrea ^a   Milne, Norah ^b   Gillespie, Brenda W ^f   Goodrich, Nathan P ^g   Everhart, James E ^h  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e UNIVERSITY OF NORTH CAROLINA   (United States)

^f UNIVERSITY OF MICHIGAN   (United States)

^g ARBOR RESEARCH COLLABORATIVE FOR HEALTH   (United States)

^h NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; CHOLIC ACID DERIVATIVE; ERYTHROMYCIN; GALACTOSE;

ADULT; ARTICLE; BODY WEIGHT; CLINICAL ARTICLE; FEMALE; HUMAN; LIVER BLOOD FLOW; LIVER LOBECTOMY; LIVER METABOLISM; LIVER REGENERATION; LIVER TRANSPLANTATION; LIVER WEIGHT; LIVING DONOR; MALE; PRIORITY JOURNAL; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; SPLEEN WEIGHT; THROMBOCYTE COUNT;

ADULT; ALANINE TRANSAMINASE; BILIRUBIN; BREATH TESTS; CAFFEINE; CHOLATES; COLORADO; ERYTHROMYCIN; FEMALE; HEPATECTOMY; HUMANS; INTERNATIONAL NORMALIZED RATIO; LINEAR MODELS; LIVER; LIVER CIRCULATION; LIVER REGENERATION; LIVER TRANSPLANTATION; LIVING DONORS; MALE; MIDDLE AGED; ORGAN SIZE; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RECOVERY OF FUNCTION; SAN FRANCISCO; SERUM ALBUMIN; TIME FACTORS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOMOGRAPHY, X-RAY COMPUTED; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84875123337     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.23592     Document Type: Article

References (29)

1. Trotter JF, Adam R, Lo CM, Kenison J,. Documented deaths of hepatic lobe donors for living donor liver transplantation. Liver Transpl 2006; 12: 1485-1488.
2. Ghobrial RM, Freise CE, Trotter JF, Tong L, Ojo AO, Fair JH, et al.; for A2ALL Study Group. Donor morbidity after living donation for liver transplantation. Gastroenterology 2008; 135: 468-476.
3. Trotter JF, Gillespie BW, Terrault NA, Abecassis MM, Merion RM, Brown RS Jr, et al.; for Adult-to-Adult Living Donor Liver Transplantation Cohort Study Group. Laboratory test results after living liver donation in the Adult-to-Adult Living Donor Liver Transplantation Cohort Study. Liver Transpl 2011; 17: 409-417.
4. Dezso K, Papp V, Bugyik E, Hegyesi H, Sáfrány G, Bödör C, et al. Structural analysis of oval-cell-mediated liver regeneration in rats. Hepatology 2012; 56: 1457-1467.
5. Seki T, Yokoyama Y, Nagasaki H, Kokuryo T, Nagino M,. Adipose tissue-derived mesenchymal stem cell transplantation promotes hepatic regeneration after hepatic ischemia-reperfusion and subsequent hepatectomy in rats. J Surg Res 2012; 178: 63-70.
6. Humar A, Kosari K, Sielaff TD, Glessing B, Gomes M, Dietz C, et al. Liver regeneration after adult living donor and deceased donor split-liver transplants. Liver Transpl 2004; 10: 374-378.
7. Nadalin S, Testa G, Malagõ M, Beste M, Frilling A, Schroeder T, et al. Volumetric and functional recovery of the liver after right hepatectomy for living donation. Liver Transpl 2004; 10: 1024-1029.
8. Pomfret EA, Pomposelli JJ, Gordon FD, Erbay N, Lyn Price L, Lewis WD, Jenkins RL,. Liver regeneration and surgical outcome in donors of right-lobe liver grafts. Transplantation 2003; 76: 5-10.
9. Jochum C, Beste M, Penndorf V, Farahani MS, Testa G, Nadalin S, et al. Quantitative liver function tests in donors and recipients of living donor liver transplantation. Liver Transpl 2006; 12: 544-549.
10. Schmidt LE, Olsen AK, Stentoft K, Rasmussen A, Kirkegaard P, Dalhoff K,. Early postoperative erythromycin breath test correlates with hepatic cytochrome P4503A activity in liver transplant recipients. Clin Pharmacol Ther 2001; 70: 446-454.
11. Wahlländer A, Mohr S, Paumgartner G,. Assessment of hepatic function. Comparison of caffeine clearance in serum and saliva during the day and at night. J Hepatol 1990; 10: 129-137.
12. Watkins PB, Murray SA, Winkelman LG, Heuman DM, Wrighton SA, Guzelian PS,. Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients. J Clin Invest 1989; 83: 688-697.
13. Keiding S,. Galactose clearance measurements and liver blood flow. Gastroenterology 1988; 94: 477-481.
14. Everson GT, Martucci MA, Shiffman ML, Sterling RK, Morgan TR, Hoefs JC,; for HALT-C Trial Group. Portal-systemic shunting in patients with fibrosis or cirrhosis due to chronic hepatitis C: the minimal model for measuring cholate clearances and shunt. Aliment Pharmacol Ther 2007; 26: 401-410.
15. Everson GT, Shiffman ML, Morgan TR, Hoefs JC, Sterling RK, Wagner DA, et al.; for HALT-C Trial Group. The spectrum of hepatic functional impairment in compensated chronic hepatitis C: results from the Hepatitis C Anti-Viral Long-Term Treatment Against Cirrhosis Trial. Aliment Pharmacol Ther 2008; 27: 798-809.
16. Everson GT, Shiffman ML, Hoefs JC, Morgan TR, Sterling RK, Wagner DA, et al.; for HALT-C Trial Group. Quantitative tests of liver function measure hepatic improvement after sustained virological response: results from the HALT-C trial. Aliment Pharmacol Ther 2009; 29: 589-601.
17. Everson GT, Shiffman ML, Hoefs JC, Morgan TR, Sterling RK, Wagner DA, et al.; for HALT-C Trial Group. Quantitative liver function tests improve the prediction of clinical outcomes in chronic hepatitis C: results from the Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis Trial. Hepatology 2012; 55: 1019-1029.
18. Hoefs JC, Wang F, Kanel G,. Functional measurement of the nonfibrotic hepatic mass in cirrhotic patients. Am J Gastroenterol 1997; 92: 2054-2058.
19. Hoefs JC, Sheikh MY, Guerrero H, Milne N,. Factors affecting the quantitative liver-spleen scan in normal individuals. Dig Dis Sci 2005; 50: 283-289.
20. Hoefs JC, Wang FW, Lilien DL, Walker B, Kanel G,. A novel, simple method of functional spleen volume calculation by liver-spleen scan. J Nucl Med 1999; 40: 1745-1755.
21. Huang H, Deng M, Jin H, Liu A, Dirsch O, Dahmen U,. Hepatic arterial perfusion is essential for the spontaneous recovery from focal hepatic venous outflow obstruction in rats. Am J Transplant 2011; 11: 2342-2352.
22. Milona A, Owen BM, van Mil S, Dormann D, Mataki C, Boudjelal M, et al. The normal mechanisms of pregnancy-induced liver growth are not maintained in mice lacking the bile acid sensor Fxr. Am J Physiol Gastrointest Liver Physiol 2010; 298: G151-G158.
23. Chen WD, Wang YD, Meng Z, Zhang L, Huang W,. Nuclear bile acid receptor FXR in the hepatic regeneration. Biochim Biophys Acta 2011; 1812: 888-892.
24. Geier A, Trautwein C,. Bile acids are "homeotrophic" sensors of the functional hepatic capacity and regulate adaptive growth during liver regeneration. Hepatology 2007; 45: 251-253.
25. Schumann R, Bonney I, McDevitt LM, Cooper JT, Cepeda MS,. Extent of right hepatectomy determines postoperative donor albumin and bilirubin changes: new insights. Liver Int 2008; 28: 95-98.
26. Dupuis RE, Williams EE, Hawke RL, Nelson AC, Johnson MW, Shrestha R,. Cytochrome P450 activity and the acute phase response in healthy donors after living donor liver transplantation (LDLT) [abstract]. Hepatology 2004; 40 (suppl S4): 561A.
27. Chen TY, Chen CL, Huang TL, Tsang LL, Wang CC, Liu YW, et al. Spleen volume and platelet count changes among donors after living donor liver transplantation. Hepatogastroenterology 2008; 55: 1211-1215.
28. Chen TY, Chen CL, Huang TL, Tsang LL, Wang CC, Wang SH, et al. Remnant liver regeneration and spleen volume changes after living liver donation: influence of the middle hepatic vein. Clin Transplant 2006; 20: 725-731.
29. Nagasako Y, Jin MB, Miyazaki H, Nakayama M, Shimamura T, Furukawa H, et al. Thrombopoietin in postoperative thrombocytopenia following living donor hepatectomy. Liver Transpl 2006; 12: 435-439.