-
1
-
-
84859169880
-
Drug development: Raise standards for preclinical cancer research
-
Begley CG, Ellis LM. Drug development: Raise standards for preclinical cancer research. Nature 2012;483:531-533.
-
(2012)
Nature
, vol.483
, pp. 531-533
-
-
Begley, C.G.1
Ellis, L.M.2
-
2
-
-
84870831020
-
Molecular genetic overlap in bipolar disorder, schizophrenia, and major depressive disorder
-
in press
-
Schulze TG, Akula N, Breuer R et al. Molecular genetic overlap in bipolar disorder, schizophrenia, and major depressive disorder. World J Biol Psychiatry 2012 (in press).
-
(2012)
World J Biol Psychiatry
-
-
Schulze, T.G.1
Akula, N.2
Breuer, R.3
-
3
-
-
84867829870
-
Individual common variants exert weak effects on the risk for autism spectrum disorders
-
Anney R, Klei L, Pinto D et al. Individual common variants exert weak effects on the risk for autism spectrum disorders. Hum Mol Genet 2012;21:4781-4792.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 4781-4792
-
-
Anney, R.1
Klei, L.2
Pinto, D.3
-
4
-
-
77956214743
-
Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells
-
Urbach A, Bar-Nur O, Daley GQ et al. Differential modeling of fragile X syndrome by human embryonic stem cells and induced pluripotent stem cells. Cell Stem Cell 2010;6:407-411.
-
(2010)
Cell Stem Cell
, vol.6
, pp. 407-411
-
-
Urbach, A.1
Bar-Nur, O.2
Daley, G.Q.3
-
5
-
-
80053948646
-
Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome
-
Sheridan SD, Theriault KM, Reis SA et al. Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome. PLoS One 2011;6:e26203.
-
(2011)
PLoS One
, vol.6
-
-
Sheridan, S.D.1
Theriault, K.M.2
Reis, S.A.3
-
6
-
-
84861849462
-
Molecular analysis of FMR1 reactivation in fragile-X induced pluripotent stem cells and their neuronal derivatives
-
Bar-Nur O, Caspi I, Benvenisty N. Molecular analysis of FMR1 reactivation in fragile-X induced pluripotent stem cells and their neuronal derivatives. J Mol Cell Biol 2012;4:180-183.
-
(2012)
J Mol Cell Biol
, vol.4
, pp. 180-183
-
-
Bar-Nur, O.1
Caspi, I.2
Benvenisty, N.3
-
7
-
-
78149488365
-
A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells
-
Marchetto MC, Carromeu C, Acab A et al. A model for neural development and treatment of Rett syndrome using human induced pluripotent stem cells. Cell 2010;143:527-539.
-
(2010)
Cell
, vol.143
, pp. 527-539
-
-
Marchetto, M.C.1
Carromeu, C.2
Acab, A.3
-
8
-
-
84864961375
-
Xchromosome inactivation in Rett syndrome human induced pluripotent stem cells
-
Cheung AY, Horvath LM, Carrel L et al. Xchromosome inactivation in Rett syndrome human induced pluripotent stem cells. Front Psychiatry 2012;3:24.
-
(2012)
Front Psychiatry
, vol.3
, pp. 24
-
-
Cheung, A.Y.1
Horvath, L.M.2
Carrel, L.3
-
9
-
-
80052155858
-
Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome
-
Kim KY, Hysolli E, Park IH. Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome. Proc Natl Acad Sci USA 2011;108:14169-14174.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 14169-14174
-
-
Kim, K.Y.1
Hysolli, E.2
Park, I.H.3
-
10
-
-
80053143413
-
Isogenic pairs of wild type and mutant induced pluripotent stem cell (iPSC) lines from Rett syndrome patients as in vitro disease model
-
Ananiev G, Williams EC, Li H et al. Isogenic pairs of wild type and mutant induced pluripotent stem cell (iPSC) lines from Rett syndrome patients as in vitro disease model. PLoS One 2011;6:e25255.
-
(2011)
PLoS One
, vol.6
-
-
Ananiev, G.1
Williams, E.C.2
Li, H.3
-
11
-
-
84870067243
-
Rett syndrome induced pluripotent stem cell-derived neurons reveal novel neurophysiological alterations
-
Farra N, Zhang WB, Pasceri P et al. Rett syndrome induced pluripotent stem cell-derived neurons reveal novel neurophysiological alterations. Mol Psychiatry 2012;17:1261-1271.
-
(2012)
Mol Psychiatry
, vol.17
, pp. 1261-1271
-
-
Farra, N.1
Zhang, W.B.2
Pasceri, P.3
-
12
-
-
84871410004
-
Somatic copy number mosaicism in human skin revealed by induced pluripotent stem cells
-
Abyzov A, Mariani J, Palejev D et al. Somatic copy number mosaicism in human skin revealed by induced pluripotent stem cells. Nature 2012;492:438-442.
-
(2012)
Nature
, vol.492
, pp. 438-442
-
-
Abyzov, A.1
Mariani, J.2
Palejev, D.3
-
13
-
-
84863229606
-
Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression
-
Cheng L, Hansen NF, Zhao L et al. Low incidence of DNA sequence variation in human induced pluripotent stem cells generated by nonintegrating plasmid expression. Cell Stem Cell 2012;10:337-344.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 337-344
-
-
Cheng, L.1
Hansen, N.F.2
Zhao, L.3
-
14
-
-
84857136772
-
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
-
Lujan E, Chanda S, Ahlenius H et al. Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. Proc Natl Acad Sci USA 2012;109:2527-2532.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 2527-2532
-
-
Lujan, E.1
Chanda, S.2
Ahlenius, H.3
-
15
-
-
52149097555
-
Regulatory networks define phenotypic classes of human stem cell lines
-
Muller FJ, Laurent LC, Kostka D et al. Regulatory networks define phenotypic classes of human stem cell lines. Nature 2008;455:401-405.
-
(2008)
Nature
, vol.455
, pp. 401-405
-
-
Muller, F.J.1
Laurent, L.C.2
Kostka, D.3
-
16
-
-
79953267538
-
A bioinformatic assay for pluripotency in human cells
-
Muller FJ, Schuldt BM, Williams R et al. A bioinformatic assay for pluripotency in human cells. Nat Methods 2011;8:315-317.
-
(2011)
Nat Methods
, vol.8
, pp. 315-317
-
-
Muller, F.J.1
Schuldt, B.M.2
Williams, R.3
-
17
-
-
84860640679
-
Erosion of dosage compensation impacts human iPSC disease modeling
-
Mekhoubad S, Bock C, de Boer AS et al. Erosion of dosage compensation impacts human iPSC disease modeling. Cell Stem Cell 2012;10:595-609.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 595-609
-
-
Mekhoubad, S.1
Bock, C.2
de Boer, A.S.3
-
18
-
-
79953001332
-
A targeted NKX2.1 human embryonic stem cell reporter line enables identification of human basal forebrain derivatives
-
Goulburn AL, Alden D, Davis RP et al. A targeted NKX2.1 human embryonic stem cell reporter line enables identification of human basal forebrain derivatives. STEM CELLS 2011;29: 462-473.
-
(2011)
STEM CELLS
, vol.29
, pp. 462-473
-
-
Goulburn, A.L.1
Alden, D.2
Davis, R.P.3
-
19
-
-
84856088804
-
Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome
-
Pasca SP, Portmann T, Voineagu I et al. Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome. Nat Med 2011;17:1657-1662.
-
(2011)
Nat Med
, vol.17
, pp. 1657-1662
-
-
Pasca, S.P.1
Portmann, T.2
Voineagu, I.3
-
20
-
-
84864506775
-
Modeling human cortical development in vitro using induced pluripotent stem cells
-
Mariani J, Simonini MV, Palejev D et al. Modeling human cortical development in vitro using induced pluripotent stem cells. Proc Natl Acad Sci USA 2012;109:12770-12775.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 12770-12775
-
-
Mariani, J.1
Simonini, M.V.2
Palejev, D.3
-
21
-
-
79953048441
-
Integrationfree induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation
-
Chiang CH, Su Y, Wen Z et al. Integrationfree induced pluripotent stem cells derived from schizophrenia patients with a DISC1 mutation. Mol Psychiatry 2011;16:358-360.
-
(2011)
Mol Psychiatry
, vol.16
, pp. 358-360
-
-
Chiang, C.H.1
Su, Y.2
Wen, Z.3
-
22
-
-
80052536392
-
RNA-Seq of human neurons derived from iPS cells reveals candidate long non-coding RNAs involved in neurogenesis and neuropsychiatric disorders
-
Lin M, Pedrosa E, Shah A et al. RNA-Seq of human neurons derived from iPS cells reveals candidate long non-coding RNAs involved in neurogenesis and neuropsychiatric disorders. PLoS One 2011;6:e23356.
-
(2011)
PLoS One
, vol.6
-
-
Lin, M.1
Pedrosa, E.2
Shah, A.3
-
23
-
-
84866398196
-
A high-throughput screen for Wnt/beta-catenin signaling pathway modulators in human iPSCderived neural progenitors
-
Zhao WN, Cheng C, Theriault KM et al. A high-throughput screen for Wnt/beta-catenin signaling pathway modulators in human iPSCderived neural progenitors. J Biomol Screen 2012;17:1252-1263.
-
(2012)
J Biomol Screen
, vol.17
, pp. 1252-1263
-
-
Zhao, W.N.1
Cheng, C.2
Theriault, K.M.3
-
24
-
-
80053595693
-
A system for performing high throughput assays of synaptic function
-
Hempel CM, Sivula M, Levenson JM et al. A system for performing high throughput assays of synaptic function. PLoS One 2011;6: e25999.
-
(2011)
PLoS One
, vol.6
-
-
Hempel, C.M.1
Sivula, M.2
Levenson, J.M.3
-
25
-
-
70349301819
-
Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs
-
Lee G, Papapetrou EP, Kim H et al. Modelling pathogenesis and treatment of familial dysautonomia using patient-specific iPSCs. Nature 2009;461:402-406.
-
(2009)
Nature
, vol.461
, pp. 402-406
-
-
Lee, G.1
Papapetrou, E.P.2
Kim, H.3
-
26
-
-
84871509371
-
Specimen collection for induced pluripotent stem cell research: Harmonizing the approach to informed consent
-
Lowenthal J, Lipnick S, Rao M et al. Specimen collection for induced pluripotent stem cell research: Harmonizing the approach to informed consent. STEM CELLS TRANSLATIONAL MEDICINE 2012;1:409-421.
-
(2012)
STEM CELLS TRANSLATIONAL MEDICINE
, vol.1
, pp. 409-421
-
-
Lowenthal, J.1
Lipnick, S.2
Rao, M.3
|