Evaluation on the Efficacy and Immunogenicity of Recombinant DNA Plasmids Expressing Spike Genes from Porcine Transmissible Gastroenteritis Virus and Porcine Epidemic Diarrhea Virus

PLoS ONE

Volumn 8, Issue 3, 2013, Pages

  Meng, Fandan ^a   Ren, Yudong ^a   Suo, Siqingaowa ^a   Sun, Xuejiao ^a   Li, Xunliang ^a   Li, Pengchong ^a   Yang, Wei ^a   Li, Guangxing ^a   Li, Lu ^a   Schwegmann Wessels, Christel ^b   Herrler, Georg ^b   Ren, Xiaofeng ^a  

^a NORTHEAST AGRICULTURAL UNIVERSITY   (China)

^b UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DNA VACCINE; GAMMA INTERFERON; NEUTRALIZING ANTIBODY; PLASMID DNA; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS SPIKE 1 PROTEIN; VIRUS SPIKE PROTEIN;

ANTIBODY DETECTION; ANTIBODY RESPONSE; ANTIBODY SPECIFICITY; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL ASSAY; CELL KINETICS; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DNA SEQUENCE; EXPRESSION VECTOR; GENE EXPRESSION; IMMUNOGENICITY; IN VITRO STUDY; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PORCINE EPIDEMIC DIARRHEA VIRUS; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN TARGETING; RECOMBINANT PLASMID; SEQUENCE ANALYSIS; TRANSMISSIBLE GASTROENTERITIS VIRUS; VACCINATION; VIRUS GENE; VIRUS NEUTRALIZATION; VIRUS SPIKE GENE;

ANIMALS; ANTIBODIES, VIRAL; CORONAVIRUS INFECTIONS; DNA, RECOMBINANT; DNA, VIRAL; GASTROENTERITIS, TRANSMISSIBLE, OF SWINE; GENES, VIRAL; INTERFERON-GAMMA; INTERLEUKIN-4; MICE; PLASMIDS; PORCINE EPIDEMIC DIARRHEA VIRUS; SWINE; SWINE DISEASES; T-LYMPHOCYTES; TRANSMISSIBLE GASTROENTERITIS VIRUS; VACCINES, DNA; VIRAL PROTEINS; VIRAL VACCINES;

EID: 84875102050     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057468     Document Type: Article

References (47)

1. Bridgen A, Duarte M, Tobler K, Laude H, Ackermann M, (1993) Sequence determination of the nucleocapsid protein gene of the porcine epidemic diarrhoea virus confirms that this virus is a coronavirus related to human coronavirus 229E and porcine transmissible gastroenteritis virus. J Gen Virol 74: 1795-1804.
2. Chasey D, Cartwright SF, (1978) Virus-like particles associated with porcine epidemic diarrhea. Res Vet 25: 255-256.
3. Cheng QH, Niu XY, (1992) Investigation on the porcine epidemic diarrhea prevalent on Qinhai. Vet Sci 22: 22-23.
4. Claerebout E, Vercauteren I, Geldhof P, Olbrechts A, Zarlenga DS, et al. (2005) Cytokine responses in immunized and non-immunized calves after Ostertagia ostertagi infection. Parasite Immunol 27: 325-331.
5. Cruz DJ, Kim CJ, Shin HJ, (2008) The GPRLQPY motif located at the carboxy-terminal of the spike protein induces antibodies that neutralize porcine epidemic diarrhea virus. Virus Res 132: 192-196.
6. DeBouck P, Callebaut P, Pensaert M, (1982) Prevalence of the porcine epidemic diarrhea (PED) virus in the pig population of different countries. Vet Soc 7: 53.
7. Delmas B, Gelfi J, Laude H, (1986) Antigenic Structure of Transmissible Gastroenteritis Virus. II Domains in the Peplomer Glycoprotein. Virol 67: 1405-1418.
8. Doyle LP, Hutchings LM, (1946) A transmissible gastroenteritis in pigs. Vet Med 108: 257-259.
9. Duarte M, Laude H, (1994) Sequence of the spike protein of the porcine epidemic diarrhea virus. Gen Virol 75: 1195-1200.
10. Duarte M, Tobler K, Bridgen A, Rasschaert D, Ackermann M, et al. (1994) Sequence analysis of the porcine epidemic diarrhea virus genome between the nucleocapsid and spike protein genes reveals a polymorphic ORF. Virology 198: 466-476.
11. Garwes DJ, Lucas MH, Higgins DA (1978/1979) Antigenicity of structural components from porcine transmissible gastroenteritis virus. Vet Microbiol 3: 179-190.
12. Goodwin RF, Jelmings AR, (1958) A highly infeetious gastroenieritis of pigs. Vet Rec 70: 271-272.
13. Isabel C, Gebauer F, Bullido MJ, Suñé C, Baay MF, et al. (1990) Localization of antigenic sites of the E2 glycoprotein of transmissible gastroenteritis coronavirus. J Gen Virol 71: 271-279.
14. Jiménez G, Castro JM, Pozzo M, (1985) Identification of a coronavirus inducing porcine gastroenteritis in Spain. Pig Vet Soc Congress 9: 186.
15. Jiménez G, Correa I, Melgosa MP, Bullido MJ, Enjuanes L, (1986) Critical epitopes in transmissible gastroenteritis virus neutralization. J Virol 60: 131-139.
16. Johnson M, Fitzgerald G, Welter MW, (1992) Six most common pathogens responsible for diarrhea in newborn pigs. Vet Med 87: 382-386.
17. Jung-Eun P, Deu JM, Cruz HJS, (2010) Trypsin-induced hemagglutination activity of porcine epidemic diarrhea virus. Arch Virol 155: 595-599.
18. Kweon CH, Kwon BJ, Jung TS, (1993) Isolation of porcine epidemic diarrhea virus (PEDV) in Korea. Korean Vet Res 33: 249-254.
19. Laude H, Chapsal JM, Gelfi J, Labiau S, Grosclaude J, (1986) Antigenic structure of transmissible gastroenteritis virus. I. Properties of monoclonal antibodies directed against virion proteins. J Gen Virol 67: 119-130.
20. Laviada MD, Videgain SP, Moreno L, Alonso F, Enjuanes L, et al. (1990) Expression of swine transmissible gastroenteritis virus envelope antigens on the surface of infeeted cells: epitopes externally exposed. Virus Res 16: 247-254.
21. Lekutis C, Shiver JW, Liu MA, Letvin NL, (1997) HIV-1 env DNA vaccine administered to rhesus monkeys elicits MHC class II-restricted CD4+ T helper cells that secrete IFN-gamma and TNF-alpha. J Immunol 158: 4471-4477.
22. Li G, Shi N, Suo S, Cui J, Zarlenga D, et al. (2012) Vaccination of Mice with ORF5 Plasmid DNA of PRRSV; Enhanced Effects by Co-immunizing with Porcine IL-15. Immunol. Invest 41: 231-248.
23. Liu MA, (2003) DNA vaccines: a review. J Intern Med 253: 402-410.
24. Liu B, Li G, Sui X, Yin J, Wang H, et al. (2009) Expression and functional analysis of porcine aminopeptidase N produced in prokaryotic expression system. J. Biotechnol 141: 91-96.
25. Margaret AL, (2011) DNA vaccines: an historical perspective and view to the future. Immunological Reviews 239: 62-84.
26. Meng F, Yin J, Li X, Yang W, Li G, et al. (2010) Production and characterization of a monoclonal antibody against spike protein of transmissible gastroenteritis virus. Hybridoma 29: 345-350.
27. Moxley RA, Olson LD, (1989) Clinical evaluation of transmissible gastroenteritis virus vaccines and vaccination procedures for inducing lactogenic immunity in sows. Vet Res 50: 111-118.
28. Pensaert M, Debouck P, (1978) A new coronavirus-like particle associated with diarrhea in swine. Virol 58: 243-247.
29. Ren XF, Yin JC, Si W, Li YJ, Liu BQ, (2006) Construction of nucleic acid vaccines containing S gene from TGEV isolate TH-98 and their immune effect in mice. Veterinary Science in China 3: 203-206 (in Chinese).
30. Robinson HL, Hunt LA, Webster RG, (1993) Protection against a lethal influenza virus challenge by immunization with a haemagglutinin-expressing plasmid DNA. Vaccine 11: 957-960.
31. Sasahara J, Harada K, Hayashi S, (1958) Studies on transmissible gastroenieritis in pig In Japan. Vet Sci 20: l-6.
32. Sestak K, Lanza I, Park SK, Weilnau PA, Saif LJ, (1996) Contribution of passive immunity to porcine respiratory coronavirus to protection against transmissible gastroenteritis virus challenge exposure in suckling pigs. J Vet. Res 57: 664-671.
33. Shuojie L, Jizhong C, Chengwu T, Yanbin M, Shuyu W, et al. (2007) Construction and Expression of DNA Vaccine pIRES-Sj97-Sj14-Sj26 and Its Immunogenicity in Mice. Med Sci 27: 625-629.
34. Spaan W, Cavanagh D, (1988) Coronavirus: structure and genome expression. Gen. Virol 69: 29-52.
35. Straw BE, Allaire SD, Mengeling WL (2000) Disease of Swine 8th ed. Beijing: The Chinese Agriculture University Press. 181-187.
36. Sturman LS, Riehard CS, Murine KV, (1985) Proteolytic Cleavage of the E2 Glycoprotein of Murine Coronavirus by Trysin and Separation of Two Different 90K Cleavage Fragments. Virol 56: 904-911.
37. Sui X, Yin J, Ren X, (2010) Antiviral effect of diammonium glycyrrhizinate and lithium chloride on cell infection by pseudorabies herpesvirus. Antiviral Res 85: 346-353.
38. Sumi T, Fukushima A, Fukuda K, Kumagai N, Nishida T, et al. (2007) Differential contributions of B7-1and B7-2 to the development of murine experimental allergic conjunctivitis. Immunology Letters 108: 62-67.
39. Sun DB, Feng L, Shi HY, Chen JF, Liu SW, et al. (2007) Spike protein region of porcine epidemic diarrhea virus is essential for induction of neutralizing antibodies. Acta Virol 51: 149-156.
40. Sun D, Feng L, Shi H, Chen J, Cui X, et al. (2008) Identification of two novel B cell epitopes on porcine epidemic diarrhea virus spike protein. Vet Microbiol 131: 73-81.
41. Sun-Hwa C, Bae JL, Kang TJ, Kim J, Chung GH, et al. (2002) Identification of the Epitope Region Capable of Inducing Neutralizing Antibodies against the Porcine Epidemic Diarrhea Virus. Mol Cells Vol 14: 295-299.
42. Tsuda T, (1997) Porcine epidemic diarrhea: Its diagnosis and control. Vet Soc 31: 21-28.
43. Ulmer JB, Donnelly JJ, Parker SE, Rhodes GH, Felgner PL, et al. (1993) Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 259: 1745-1749.
44. Ulmer JB, Deck RR, DeWitt CM, Donnelly JJ, Friedman A, et al. (1997) Induction of immunity by DNA vaccination: application to influenza and tuberculosis. Behring Inst Mitt 98: 79-86.
45. Ulmer JB, Fu TM, Deck RR, Friedman A, Guan L, et al. (1998) Protective CD4+ and CD8+ T cells against influenza virus induced by vaccination with nucleoprotein DNA. J Virol 72: 5648-5653.
46. Wang B, Ugen KE, Srikantan V, Agadjanyan MG, Dang K, et al. (1993) Gene inoculation generates immune responses against human immunodeficiency virus type 1. Proc Natl Acad Sci USA 90: 4156-4160.
47. Wood EN, (1977) An apparently new syndrome of porcine epidemic diarrhoea. Vet Rec 100: 243-244.