Ultrasound-Enhanced Delivery of Antibiotics and Anti-Inflammatory Drugs Into the Eye

Ultrasound in Medicine and Biology

Volumn 39, Issue 4, 2013, Pages 638-646

  Nabili, Marjan ^a   Patel, Hetal ^a   Mahesh, Sankaranarayana P ^b   Liu, Ji ^b   Geist, Craig ^b   Zderic, Vesna ^a  

^a George Washington University   (United States)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Cornea; Drug delivery; In vitro; Ocular diseases; Sonophoresis; Therapeutic ultrasound

Indexed keywords

ANTIBIOTICS; DRUG DELIVERY; SODIUM;

CORNEA; IN-VITRO; OCULAR DISEASE; SONOPHORESIS; THERAPEUTIC ULTRASOUND;

ULTRASONICS;

ANTIBIOTIC AGENT; ANTIINFLAMMATORY AGENT; DEXAMETHASONE; FLUORESCEIN SODIUM; TOBRAMYCIN;

AMPLIFIER; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORNEA EPITHELIUM; CORNEA PERMEABILITY; DRUG PENETRATION; IN VITRO STUDY; INTRAOCULAR DRUG ADMINISTRATION; MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; PULSE GENERATOR; RABBIT; ULTRASOUND; ULTRASOUND TRANSDUCER;

EID: 84875101139     PISSN: 03015629     EISSN: 1879291X     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2012.11.010     Document Type: Article

References (70)

1. Abe H., Kuroki M., Tachibana K., Li T., Awasthi A., Ueno A., Matsumoto H., Imakiire T., Yamaguchi Y., Yamada H., Ariyoshi A., Kuroki M. Targeted sonodynamic therapy of cancer using a photosensitizer conjugated with antibody against carcinoembryonic antigen. Anticancer Res 2002, 22:1575-1580.
2. Ahmed I., Gokhale R.D., Shah M.V., Patton T.F. Physicochemical determinants of drug diffusion across the conjunctiva, sclera, and cornea. J Pharm Sci 1987, 76:583-586.
3. Ahmed I., Patton T.F. Disposition of timolol and inulin in the rabbit eye following corneal versus non-corneal absorption. Int J Pharm 1987, 38:9-21.
4. Ali M., Byrne M.E. Challenges and solutions in topical ocular drug-delivery systems. Expert Rev Clin Pharmacol 2008, 1:145-161.
5. Barnett S.B., Ter Haar G.R., Ziskin M.C., Rott H.D., Duck F.A., Maeda K. International recommendations and guidelines for the safe use of diagnostic ultrasound in medicine. Ultrasound Med Biol 2000, 26:355-366.
6. Bartlett J.D., Jaanus S.D. Clinical ocular pharmacology 1984, Butterworth-Heinemann, Woburn, MA USA.
7. Boucaud A., Montharu J., Machet L., Arbeille B., Machet M., Patat F., Vaillant L. Clinical, histologic, and electron microscopy study of skin exposed to low frequency ultrasound. Anat Rec Part A 2001, 264:114-119.
8. Cherkasov I.S., Marmur R.K., Radkovskaia A.I. Phonophoresis of hypotensive agents in the treatment of simple glaucoma. Oftalmol Zh 1974, 29:114-118.
9. Cheung A.C.Y., Yu Y., Tay D., Wong H.S., Ellis-Behnke R., Chau Y. Ultrasound-enhanced intrascleral delivery of protein. Int J Pharm 2010, 401:16-24.
10. Christensen D.A. John Wiley and Sons 1988, Ultrasonic bioinstrumentation, Hoboken, NJ, 91-94.
11. Clark A.F., Yorio T. Ophthalmic drug discovery. Nature Rev 2003, 2:448-459.
12. Cucevic V., Brown A.S., Foster F.S. Thermal assessment of 40 MHz pulsed Doppler ultrasound in human eye. Ultrasound Med Biol 2005, 31:565-573.
13. Cui J., Wei Y., Wang H. The study of low frequency ultrasound of enhance transdermal drug delivery 2007, IEEE/ICME International Conference on Complex Medical Engineering, Beijing, China, p.1221-1224.
14. Davies N.M. Biopharmaceutical considerations in topical ocular drug delivery. Clin Exp Pharmacol Physiol 2000, 27:558-562.
15. Davis J.L., Gilger B.C., Robinson M.R. Novel approaches to ocular drug delivery. Curr Opin Mol Ther 2004, 6:195-205.
16. DiCicco M., Duong T., Chu A., Jansen S.A. Tobramycin and gentamycin elution analysis between Two in situ polymerizable orthopedic composites. J Biomed Mater Res B 2003, 65:137-149.
17. Doane M.G., Jensen A.D., Dohlman C.H. Penetration routes of topically applied eye medications. Am J Ophthalmol 1978, 85:383-386.
18. Efron N., Young G., Brennan N.A. Ocular surface temperature. Curr Eye Res 1989, 8:901-906.
19. Egorov E.A., Kriukova M.B., Khabush T., Kriukov A.I. Results of intraocular pharmaco-physical therapy in inflammatory diseases of the cornea. Vestn Oftalmol 1995, 111:31-34.
20. Fick A. On diffusion. Poggendorff's Ann 1855, 114:59.
21. Filippenko V.I., Tretiak V.V. The treatment of eye diseases using the Gamma-G ultrasonic apparatus. Voen Med Zh 1989, 30-31.
22. Friedman D.S., Congdon N., Kempen J., Tielsch J.M. Vision problems in the U.S.: Prevalence of adult vision impairment and age-related eye disease in America 2002, National Eye Institute, Bethesda, MD.
23. Gaudana R., Ananthula H., Parenky A., Mitra A.K. Ocular drug delivery. AAPS J 2010, 12:348-360.
24. Geroski D.H., Edelhauser H.F. Drug delivery for posterior segment eye disease. Invest Ophthalmol Vis Sci 2000, 41:961-964.
25. Green K., Downs S.J. Corneal membrane water permeability as a function of temperature. Invest Ophthalmol 1976, 15:304-307.
26. Gvarishvili E.P., Dushin N.V. Effect of superphonoelectrophoresis on chorioretinal dystrophy [in Spanish]. Vestn Oftalmol 1999, 115:19-21.
27. Guzman H.R., Nguyen D.X., McNamara A.J., Prausnitz M.R. Equilibrium loading of cells with macromolecules by ultrasound: Effects of molecular size and acoustic energy. J Pharm Sci 2002, 91:1693-1701.
28. Gwon A. The rabbit in cataract/IOL surgery. Animal models in eye research 2008, 184-199. Elsevier, San Diego, CA. 1st edition. P.A. Tsonic (Ed.).
29. Hughes P.M., Mitra A.K. Overview of ocular drug delivery and iatrogenic ocular cytopathologies. Ophthalmic drug delivery systems. Drugs and the pharmaceutical sciences, Volume 58 1993, 1-27. Marcel Dekker, New York, NY. A.K. Mitra (Ed.).
30. Iakimenko S.A., Chalanova R.I., Artemov A.V. The usage of lekozim phonophoresis for the treatment of eye burns [Russian]. Oftalmol Zh 1989, 492-497.
31. Janoria K.G., Gunda S., Boddu S.H., Mitra A.K. Novel approaches to retinal drug delivery. Expert Opin Drug Deliv 2007, 4:371-388.
32. Ke T.L., Clark A.F., Gracy R.W. Age-related permeability changes in rabbit corneas. J Ocul Pharmacol Ther 1999, 15:513-523.
33. Kodama T., Aoi A., Vassaux G., Mori S., Morikawa H., Koshiyama K.C., Yano T., Fujiikawa S., Tomita Y. A noninvasive tissue-specific molecular delivery method of cancer gene therapy. Minim Invasive Ther Allied Technol 2006, 15:226-229.
34. Kowalczuk L., Boudinet M., El Sanharawi M., Touchard E., Naud M.C., Saïed A., Jeanny J.C., Behar-Cohen F., Laugier P. In vivo gene transfer into the ocular ciliary muscle mediated by ultrasound and microbubbles. Ultrasound Med Biol 2011, 37:1814-1827.
35. Lawrie A., Brisken A.F., Francis S.E., Tayler D.I., Chamberlain J., Crossman D.C., Cumberland D.C., Newman C.M. Ultrasound enhances reporter gene expression after transfection of vascular cells in vitro. Circulation 1999, 99:2617-2620.
36. Lighthill J. Acoustic streaming. J Sound Vibration 1987, 61:564.
37. Liu J., Lewis T.N., Prausnitz M.R. Non-invasive assessment and control of ultrasound-mediated membrane permeabilization. Pharm Res 1998, 15:918-924.
38. Leighton T.G. The acoustic bubble 1994, Academic Press, San Diego.
39. Marmur R.K., Moiseeva N.N., Korkhov S.S. Current state and perspectives of further development of phonophoresis of drugs in ophthalmology (review of the literature) [in Russian]. Oftalmol Zh 1979, 34:68-73.
40. Martini F.H., Bartholomew E.F. Essentials of anatomy and physiology 2007, Pearson Education, San Francisco, 61-70. 4th edition.
41. Miller D.L. A review of the ultrasonic bioeffects of microsonation, gas-body activation, and related cavitation-like phenomena. Ultrasound Med Biol 1987, 13:443-470.
42. Miller D.L., Pislaru S.V., Greenleaf J.E. Sonoporation: Mechanical DNA delivery by ultrasonic cavitation. Somat Cell Mol Genet 2002, 27:115-134.
43. Mitragotri S., Edwards D.A., Blankschtein D., Langer R. A mechanistic study of ultrasonically enhanced transdermal drug delivery. J Pharm Sci 1995, 84:697-706.
44. Mitragotri S. Healing sound: the use of ultrasound in drug delivery and other therapeutic applications. Nat Rev 2005, 4:255-260.
45. Nishida T. Cornea. Cornea: Fundamentals, diagnosis, and management 2005, Volume 1:3-26. Elsevier Mosby, Philadelphia. 2nd edition. J.H. Krachmer, M.J. Mannis, E.J. Holland (Eds.).
46. Nuritdinov V.A. Phonophoresis and cavitation [in Russian]. Vestn Oftalmol 1981, 56-58.
47. Paliwal S., Mitragotri S. Ultrasound-induced cavitation: applications in drug and gene delivery. Informa Healthcare Expert Opinion 2006, 3:713-726.
48. Panova I.G., Fateeva V.I., Petrishcheva T.S., Fridman F.E. A pharmacokinetic study of para-aminobenzoic acid administered into the rabbit eye by phonophoresis [in Russian]. Izv Akad Nauk Ser Biol 1995, 4:487-489.
49. Pavan-Langston D. Manual of ocular diagnosis and therapy 2008, Lippincott Williams and Wilkins, Philadelphia.
50. Polat B.E., Hart D., Langer R., Blankschtein D. Ultrasound-mediated transdermal drug delivery: mechanisms, scope, and emerging trends. J Control Release 2011, 152:330-348.
51. Prausnitz M.R., Noonan J.S. Permeability of cornea, sclera, and conjunctiva: a literature analysis for drug delivery to the eye. J Pharm Sci 1998, 87:1479-1488.
52. Reddy I.K., Ganesan M. Ocular therapeutics and drug delivery: A multi-disciplinary approach 1996, Technomic, Lancaster, PA.
53. Saroha K., Sharma B., Yadav B. Sonophoresis: An advanced tool in transdermal drug delivery system. Int J Curr Pharm Res 2011, 3:89-97.
54. Sasaki H., Igarashi Y., Nagano T., Nishida K., Nakamura J. Different effects of absorption promoters on corneal and conjunctival penetration of ophthalmic beta-blockers. Pharm Res 1995, 12:1146-1150.
55. Schoenwald R.D. Ocular pharmacokinetics. Textbook of ocular pharmacology 1997, 119-139. Lippincott-Raven, Philadelphia, PA. T.J. Zimmerman, K. Kooner, M. Sharir (Eds.).
56. Short B. Safety Evaluation of ocular drug delivery formulations: techniques and practical considerations. Soc Toxicol Pathol 2008, 36:49-62.
57. Silverman R.H., Lizzi F.L., Ursea B.G., Cozzarelli L., Ketterling J.A., Deng C.X., Folberg R., Coleman D.J. Safety levels for exposure of cornea and lens to very high-frequency ultrasound. J Ultrasound Med 2001, 20:979-986.
58. Snell R., Lemp M. Clinical anatomy of the eye 1998, Blackwell Science, London. 2nd edition.
59. Tachibana K., Tachibana S. The use of ultrasound for drug delivery. Echocardiography 2001, 18:323-328.
60. Tang H., Mitragotri S., Blankschtein D., Langer R. Theoretical description of transdermal transport of hydrophilic permeants: Application to low-frequency sonophoresis. J Pharm Sci 2001, 90:545-568.
61. Tang H., Wang C.C., Blankschtein D., Langer R. An investigation of the role of cavitation in low-frequency ultrasound-mediated transdermal drug transport. Pharm Res 2002, 19:1160-1169.
62. Taniyama Y., Tachibana K., Hiraoka K., Namba T., Yamasaki K., Hashiya N., Aoki M., Ogihara T., Yasufumi K., Morishita R. Local delivery of plasmid DNA into rat carotid artery using ultrasound. Circulation 2002, 105:1233-1239.
63. Tegtmeyer S., Papantoniou I., Muller-Goymann C.C. Reconstruction of an in vitro cornea and its use for drug permeation studies from different formulations containing pilocarpine hydrochloride. Eur J Pharm Biopharm 2001, 51:119-125.
64. Tezel A., Mitragotri S. Interactions of inertial cavitation bubbles with stratum corneum lipid bilayers during low frequency sonophoresis. Biophys J 2003, 85:3502-3512.
65. Tsok R.M. Phonophoresis in various diseases of the anterior segment of the eye [in Russian]. Oftalmol Zh 1979, 34:73-76.
66. Tsok R.M., Gereliuk I.P., Tsok O.B., Kaminskii I.M. The effect of ultrasonic oscillations of different frequencies on radionuclide accumulation in the eye tissues [in Russian]. Oftalmol Zh 1990, 46-49.
67. Ueda H., Sugibayashi K., Morimoto Y. Skin penetration-enhancing effect of drugs by phonophoresis. J Control Release 1995, 37:291-297.
68. Yamaguchi K., Barbe M.F., Brown I.R., Tytell M. Induction of stress (heat shock) protein 70 and its mRNA in rat corneal epithelium by hyperthermia. Curr Eye Res 1990, 9:913-918.
69. Zderic V., Clark J.I., Martin R.W., Vaezy S. Transcorneal drug delivery using 880 KHz ultrasound. Cornea 2004, 23:804-811.
70. Zderic V., Clark J.I., Vaezy S. Drug delivery into the eye with the use of ultrasound. J Ultrasound Med 2004, 23:1349-1359.