Systemic pregabalin attenuates facial hypersensitivity and noxious stimulus-evoked release of glutamate in medullary dorsal horn in a rodent model of trigeminal neuropathic pain

Neurochemistry International

Volumn 62, Issue 6, 2013, Pages 831-835

  Kumar, Naresh ^a,b   Cherkas, Pavel S ^b   Varathan, Vidya ^b   Miyamoto, Makiko ^b,d   Chiang, Chen Yu ^b   Dostrovsky, Jonathan O ^b,c   Sessle, Barry J ^b,c   Coderre, Terence J ^a  

^a MCGILL UNIVERSITY   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d NIHON UNIVERSITY   (Japan)

Author keywords

Glutamate; Medullary dorsal horn; Neuropathic pain; Nociception; Pregabalin; Tooth pulp

Indexed keywords

ALLYL ISOTHIOCYANATE; GLUTAMIC ACID; PREGABALIN; SODIUM CHLORIDE;

AMINO ACID BLOOD LEVEL; ANALYSIS OF VARIANCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DATA ANALYSIS; DIALYSATE; DISEASE MODEL; DRUG EFFECT; FACIAL MECHANICAL HYPERSENSITIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VIVO STUDY; INFRAORBITAL NERVE; LOW DRUG DOSE; MALE; MEDULLA OBLONGATA; MICRODIALYSIS; NERVE TRANSECTION; NOCICEPTION; NOCICEPTIVE STIMULATION; NONHUMAN; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; SPINAL CORD DORSAL HORN; STIMULATION; TOOTH PULP; TRIGEMINUS NEURALGIA;

ANALGESICS; ANALYSIS OF VARIANCE; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DATA INTERPRETATION, STATISTICAL; DENTAL PULP; FACIAL PAIN; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; MALE; MEDIODORSAL THALAMIC NUCLEUS; MICE; MICE, INBRED C57BL; MICRODIALYSIS; MUSTARD PLANT; NEURALGIA; PHYSICAL STIMULATION; PLANT OILS; RATS; RATS, SPRAGUE-DAWLEY; TRIGEMINAL NEURALGIA;

ANIMALIA; RODENTIA;

EID: 84875070102     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2013.02.022     Document Type: Article

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