Immune system and gut flora interactions are important episodes in metabolic diseases

Journal of Gastrointestinal and Liver Diseases

Volumn 21, Issue 4, 2012, Pages 347-348

  Jain, Shalini ^a   Marotta, Francesco ^b   Catanzaro, Roberto ^c   Yadav, Hariom ^a  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b ReGenera Research Group for Aging Intervention   (United States)

^c UNIVERSITY OF CATANIA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOCIN; CHOLECYSTOKININ; CYTOKINE; LEPTIN; LIPOPOLYSACCHARIDE; PEPTIDE YY; PROBIOTIC AGENT;

ADIPOSE TISSUE; DIABETES MELLITUS; EDITORIAL; IMMUNE RESPONSE; IMMUNE SYSTEM; INFLAMMATION; INSULIN SENSITIVITY; INTESTINE FLORA; MACROPHAGE; METABOLIC DISORDER; NATURAL KILLER CELL; NONHUMAN; OBESITY; PEYER PATCH; T LYMPHOCYTE;

GASTROINTESTINAL TRACT; HUMANS; IMMUNITY, MUCOSAL; METABOLIC DISEASES;

EID: 84875062901     PISSN: 18418724     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial

References (17)

1. Konig W. Role of the immune system in recovery from infection. Respiration 1993; 60 Suppl 1: 16-24.
2. Nagura H. Mucosal defense mechanism in health and disease. Role of the mucosal immune system. Acta Pathol Jpn 1992; 42: 387-400.
3. James SP. The gastrointestinal mucosal immune system. Dig Dis 1993; 11: 146-156.
4. Kau AL, Ahern PP, Griffn NW, Goodman AL, Gordon JI. Human nutrition, the gut microbiome and the immune system. Nature 2011; 474: 327-336.
5. Flo J, Elias F, Benedetti R, Massouh E. Reversible effects on B and T cells of the gut-associated lymphoid tissues in rats malnourished during suckling: impaired induction of the immune response to intra-Peyer patches immunization with cholera toxin. Clin Immunol Immunopathol 1996; 80: 147-154.
6. Goto Y, Kiyono H. Epithelial barrier: an interface for the cross- communication between gut fora and immune system. Immunol Rev 2012; 245: 147-163.
7. Small CJ, Bloom SR. Gut hormones as peripheral anti obesity targets. Curr Drug Targets CNS Neurol Disord 2004; 3: 379-388.
8. Bajzer M, Seeley RJ. Physiology: obesity and gut fora. Nature 2006; 444: 1009-1010.
9. Shah PK. Innate immune pathway links obesity to insulin resistance. Circ Res 2007; 100: 1531-1533.
10. Emanuela F, Grazia M, Marco de R, Maria Paola L, Giorgio F, Marco B. Infammation as a link between obesity and metabolic syndrome. J Nutr Metab 2012; 2012: 476380.
11. de Heredia FP, Gomez-Martinez S, Marcos A. Obesity, infammation and the immune system. Proc Nutr Soc 2012; 71: 332-338.
12. Karalis KP, Giannogonas P, Kodela E, Koutmani Y, Zoumakis M, Teli T. Mechanisms of obesity and related pathology: linking immune responses to metabolic stress. FEBS J 2009; 276: 5747-5754.
13. Bertola A, Bonnafous S, Anty R, et al. Hepatic expression patterns of infammatory and immune response genes associated with obesity and NASH in morbidly obese patients. PloS One 2010; 5: e13577.
14. Marti A, Marcos A, Martinez JA. Obesity and immune function relationships. ObesRev 2001; 2: 131-140.
15. Tu YF, Tsai YS, Wang LW, Wu HC, Huang CC, Ho CJ. Overweight worsens apoptosis, neuroinfammation and blood-brain barrier damage after hypoxic ischemia in neonatal brain through JNK hyperactivation. J Neuroinfammation 2011; 8: 40.
16. Cani PD, Amar J, Iglesias MA, et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes 2007; 56: 1761-1772.
17. Yadav H, Jain S, Marotta F. Probiotics mediated modulation of gut- fora might Bbe a biotherapeutical approach for obesity and type 2 diabetes. JPDBD 2011; 01: 107e.