Common laboratory tests predict imminent death in ward patients

Resuscitation

Volumn 84, Issue 3, 2013, Pages 280-285

  Loekito, Elsa ^a   Bailey, James ^a   Bellomo, Rinaldo ^b,c   Hart, Graeme K ^b   Hegarty, Colin ^b   Davey, Peter ^b   Bain, Christopher ^d   Pilcher, David ^d   Schneider, Hans ^d  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b AUSTIN HOSPITAL   (Australia)

^c MONASH UNIVERSITY   (Australia)

^d ALFRED HOSPITAL   (Australia)

Author keywords

Biochemistry; Illness severity score; Mortality; Prediction; Rapid response team

Indexed keywords

AGED; ARTICLE; COHORT ANALYSIS; HOSPITAL ADMISSION; HUMAN; LABORATORY TEST; MAJOR CLINICAL STUDY; MORTALITY; OBSERVATIONAL STUDY; PREDICTION; PREDICTIVE VALUE; PRIORITY JOURNAL; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; TEACHING HOSPITAL; WARD;

AGED; CAUSE OF DEATH; CRITICAL ILLNESS; DIAGNOSTIC TESTS, ROUTINE; FEMALE; HOSPITAL MORTALITY; HOSPITAL RAPID RESPONSE TEAM; HUMANS; MALE; MODELS, THEORETICAL; PREDICTIVE VALUE OF TESTS; RETROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; VICTORIA;

EID: 84875053194     PISSN: 03009572     EISSN: 18731570     Source Type: Journal    
DOI: 10.1016/j.resuscitation.2012.07.025     Document Type: Article

References (56)

1. Brennan T.A., Leape L.L., Laird N.M., et al. Incidence of adverse events and negligence in hospitalized patients: results of the Harvard medical practice study I. Qual Saf Health Care 2004, 13:145-151.
2. Baker G.R., Norton P.G., Flintoft V., et al. The Canadian adverse events study: the incidence of adverse events among hospital patients in Canada. CMAJ 2004, 170:1678-1686.
3. Vincent C., Neale G., Woloshynowych M. Adverse events in British hospitals: preliminary retrospective record review. BMJ 2001, 322:517-519.
4. Buist M.D., Jarmolowski E., Burton P.R., et al. Recognising clinical instability in hospital patients before cardiac arrest or unplanned admission to intensive care. A pilot study in a tertiary-care hospital. MJA 1999, 171:22-32.
5. Bellomo R., Goldsmith D., Uchino S., et al. A prospective before-and-after trial of a medical emergency team. MJA 2003, 179:283-287.
6. Buist M., Harrison J., Abaloz E., Van Dyke S. Recognizing clinical six year audit of cardiac arrests and medical emergency team calls in an Australian outer metropolitan teaching hospital. BMJ 2007, 335:1210-1212.
7. Lee A., Bishop G., Hillman K., Daffurn K. The medical emergency team. Anaesth Intensive Care 1995, 23:183-186.
8. Jones D.A., DeVita M.A., Bellomo R. Current concepts: rapid response teams. N Engl J Med 2011, 365:139-146.
9. DeVita M.A., Bellomo R., Hillman K., et al. Findings of the first consensus conference on medical emergency teams. Crit Care Med 2006, 34:2463-2478.
10. England K., Bion J.F. Introduction of medical emergency teams in Australia and New Zealand: a multicentre study. Crit Care 2008, 12:151.
11. Casamento A.J., Dunlop C., Jones D.A., Duke G. Improving the documentation of medical emergency team reviews. Crit Care Resusc 2008, 10:29-35.
12. Cretikos M.A., Chen J., Hillman K.M., et al. The effectiveness of implementation of the medical emergency team (MET) system and factors associated with use during the MERIT study. Crit Care Resusc 2007, 9:206-212.
13. Buist M., Bellomo R. MET. The emergency medical team or the medical education team. Crit Care Resusc 2004, 6:88-91.
14. Jones D., Bellomo R., Bates S., et al. Patient monitoring and the timing of cardiac arrests and medical emergency team calls in a teaching hospital. Intensive Care Med 2006, 32:1352-1356.
15. Downey A.W., Quach J.L., Haase M., et al. Characteristics and outcomes of patients receiving a medical emergency team review for acute change in conscious state or arrhythmias. Crit Care Med 2008, 36:477-481.
16. Quach J.L., Downey A.W., Haase M., et al. Characteristics and outcomes of patients receiving a medical emergency team review for respiratory distress or hypotension. J Crit Care 2008, 23:325-331.
17. MERIT Study Investigators Introduction of the medical emergency team (RRT) system: a cluster-randomised controlled trial. Lancet 2005, 365:2091-2097.
18. Chen J., Bellomo R., Flabouris A., et al. The relationship between early emergency team calls and serious adverse events. Crit Care Med 2009, 37:148-153.
19. Zimmerman J.E., Kramer A.A. Outcome prediction in critical care: the acute physiology and chronic health evaluation models. Curr Opin Crit Care 2008, 14:491-497.
20. Vasilevskis E.E., Kuzniewicz M.W., Cason B.A., et al. Mortality probability model III and simplified acute physiology score II: assessing their value in predicting length of stay and comparison to APACHE IV. Chest 2009, 136:89-101.
21. Pine M., Jones B., Lou Y.B. Laboratory values improve predictions of hospital mortality. Int J Qual Health Care 1998, 10:491-501.
22. Prytherch D.R., Sirl J.S., Schmidt P., Featherstone P.I., Weaver P.C., Smith G.B. The use of routine laboratory data to predict in-hospital death in medical admissions. Resuscitation 2005, 66:203-207.
23. King G., Zeng L. Logistic regression in rare events data. Polit Analysis 2001, 9:137-163.
24. Kramer A.A., Zimmernman J.E. Assessing the calibration of mortality benchmarks in critical care: the Hosmer-Lemeshow test revisited. Crit Care Med 2007, 35:2052-2056.
25. Uchino S., Bellomo R., Goldsmith D., et al. An assessment of the RIFLE criteria for acute renal failure in hospitalized patients. Crit Care Med 2006, 34:1913-1917.
26. Florath I., Albert A., Hassanein W., et al. Current determinants of 30-day and 3-month mortality in over 2000 aortic valve replacements: impact of routine laboratory parameters. Eur J Cardiothorac Surg 2006, 30:716-721.
27. Subbe C.P., Kruger M., Rutherford P., Gemmel L. Validation of a modified early warning score in medical admissions. QJM 2001, 94:125-131.
28. Goldhill D.R., NcBarry A.F. Physiological abnormalities in early warning scores are related to mortality in adult inpatients. Br J Anaesth 2004, 92:882-884.
29. Prytherch D.R., Sirl J.S., Weaver P.C., Schmidt P., Higgins B., Sutton G.L. Towards a national clinical minimum data set for general surgery. Br J Surg 2003, 90:1300-1305.
30. Vroonhof K., van Solinge W.W., Rovers M.M., Huisman A. Differences in mortality on the basis of laboratory parameters in an unselected population at the emergency department. Clin Chem Lab Med 2005, 43:536-541.
31. Hucker T.R., Mitchell G.P., Blake L.D., et al. Identifying the sick: can biochemical measurements be used to aid decision making on presentation to the accident and emergency department. Br J Anaesth 2005, 94:735-741.
32. Vroonhof K., van Solinge W.W., Rovers M.M., Huisman A. Differences in mortality on the basis of complete blood count in an unselected population at the emergency department. Lab Hematol 2006, 12:134-138.
33. Froom P., Shimoni Z. Prediction of hospital mortality rates by admission laboratory tests. Clin Chem 2006, 52:325-328.
34. ten Boekel E., Vroonhof K., Huisman A., van Kampen C., de Kieviet W. Clinical laboratory findings associated with in-hospital mortality. Clin Chim Acta 2006, 372:1-13.
35. Asadollahi K., Hastings I.M., Beeching N.J., Gill G.V. Laboratory risk factors for hospital mortality in acutely admitted patients. QJM 2007, 100:501-507.
36. Novack V., Pencina M., Zahger D., et al. Routine laboratory results and thirty day and one-year mortality risk following hospitalization with acute decompensated heart failure. PLoS One 2010, 5:e12184.
37. Asadollahi K., Hastings I.M., Gill G.V., Beeching N.J. Prediction of hospital mortality from admission laboratory data and patient age: a simple model. Emerg Med Australas 2011, 23:354-363.
38. Gao H., McDonnell M., Harrison D., et al. Systematic review and evaluation of physiological track and trigger warning systems for identifying at-risk patients on the ward. Intensive Care Med 2007, 33:667-679.
39. Prytherch D.R., Smith G.B., Schmidt P.E., Featherstone P.I. ViEWS - towards a national early score for detecting adult inpatient deterioration. Resuscitation 2010, 81:932-937.
40. Bleyer A.J., Vidya S., Russell G.B., et al. Longitudinal analysis of one million vital signs in patients in an academic medical center. Resuscitation 2011, 82:1387-1392.
41. Claessens Y.E., Mathevon T., Kierzek G., et al. Accuracy of C-reactive protein, procalcitonin, and mid-regional pro-atrial natriuretic peptide to guide site of care of community-acquired pneumonia. Intensive Care Med 2010, 36:799-809.
42. Venge P., Johnston N., Lindahl B., James S. Normal plasma levels of cardiac troponin I measured by the high-sensitivity cardiac troponin I access prototype assay and the impact on the diagnosis of myocardial ischemia. J Am Coll Cardiol 2009, 54:1165-1172.
43. Waldo S.W., Beede J., Isakson S., et al. Pro-B-type natriuretic peptide levels in acute decompensated heart failure. J Am Coll Cardiol 2008, 51:1874-1882.
44. Haase M., Bellomo R., Devarajan P., et al. Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis. Am J Kidney Dis 2009, 54:1012-1024.
45. Walshe C.M., Odejayi F., Ng S., Marsh B. Urine glutathione S-transferase as an early marker for renal dysfunction in patients admitted to intensive care with sepsis. Crit Care Resusc 2009, 11:204-209.
46. Bagshaw S.M. Subclinical acute kidney injury: a novel biomarker-defined syndrome. Crit Care Resusc 2011, 13:201-203.
47. Vetro J., Natarajan D.K., Mercer I., et al. Antecedents to cardiac arrests in a hospital equipped with a medical emergency team. Crit Care Resusc 2011, 13:162-166.
48. Trinkle R.M., Flabouris A. Medical reviews before cardiac arrest, medical emergency call or unanticipated intensive care unit admission: their nature and impact on patient outcome. Crit Care Resusc 2011, 13:175-180.
49. Knott C.I., Psirides A.J., Young P.J., Sim D. A retrospective cohort study of the effect of medical emergency teams on documentation of advance care directives. Crit Care Resusc 2011, 13:167-174.
50. Sharek P.J., Parast L.M., Leong K., et al. Effect of a rapid response team on hospital-wide mortality and code rates outside the ICU in a Children's hospital. JAMA 2007, 298:2267-2274.
51. Calzavacca P., Licari E., Tee A., et al. A prospective study of factors influencing the outcome of patients after a medical emergency team review. Intensive Care Med 2008, 34:2112-211652.
52. Kucher N., Koo S., Quiroz R., et al. Electronic alerts to prevent venous thromboembolism among hospitalized patients. N Engl J Med 2005, 352:969-977.
53. Jones S., Mullally M., Ingleby S., et al. Bedside electronic capture of clinical observations and automated clinical alerts to improve compliance with an early warning score protocol. Crit Care Resusc 2011, 13:83-88.
54. Jones D., Bellomo R., Bates S., et al. Long term effect of a medical emergency team on cardiac arrests in a teaching hospital. Crit Care 2005, 9:R808-R815.
55. Warrillow S.J., Bellomo R., Davey P., Birkmeyer J. Major surgery in Victoria and the United States: a comparison of hospital mortality in older patients. Crit Care Resusc 2008, 10:288-295.
56. Peabody J.W., Bickel S.R., Lawson J.S. The Australian health care system. Are the incentives down under right side up?. JAMA 1996, 276:1944-1950.