KATP channels are up-regulated with increasing age in human myometrium

Mechanisms of Ageing and Development

Volumn 134, Issue 3-4, 2013, Pages 98-102

  Du, Qingyou ^a   Jovanović, Sofija ^a   Tulić, Lidija ^b   Šljivančanin, DragiŠa ^b   Jack, David W ^a   ŽiŽić, Vojislav ^b   Abdul, Khaja Shameem Mohammed ^a   Tulić, Ivan ^b   Jovanović, Aleksandar ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Ageing; ATP sensitive K+ channels; Partiurent; Pregnancy; Uterus

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.1; MESSENGER RNA; SULFONYLUREA RECEPTOR; SULFONYLUREA RECEPTOR 1; SULFONYLUREA RECEPTOR 2A; SULFONYLUREA RECEPTOR 2B; UNCLASSIFIED DRUG; UK ATP 1 POTASSIUM CHANNEL; UK-ATP-1 POTASSIUM CHANNEL;

ADULT; AGING; ARTICLE; BIRTH; CONTROLLED STUDY; ENZYME REGULATION; FEMALE; HUMAN; HYSTERECTOMY; MYOMETRIUM; PREGNANCY; PREGNANCY COMPLICATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; CESAREAN SECTION; GENE EXPRESSION REGULATION; LABOR; MATERNAL AGE; METABOLISM; MIDDLE AGED; PHYSIOLOGY; UTERUS CONTRACTION;

ADULT; AGING; CESAREAN SECTION; FEMALE; GENE EXPRESSION REGULATION; HUMANS; HYSTERECTOMY; KATP CHANNELS; LABOR, OBSTETRIC; MATERNAL AGE; MIDDLE AGED; MYOMETRIUM; PREGNANCY; RNA, MESSENGER; UTERINE CONTRACTION; YOUNG ADULT;

EID: 84875053110     PISSN: 00476374     EISSN: 18726216     Source Type: Journal    
DOI: 10.1016/j.mad.2013.01.003     Document Type: Article

References (24)

1. Brainard A.M., Korovkina V.P., England S.K. Potassium channels and uterine function. Seminars in Cell and Developmental Biology 2007, 18:332-339.
2. Budas G.R., Sukhodub A., Alessi D.R., Jovanović A. 3'-Phosphoinositide-dependent kinase-1 (PDK1) is essential for ischaemic preconditioning of the myocardium. The FASEB Journal 2006, 20:2556-2558.
3. Cleary-Goldman J., Malone F.D., Vidaver J., Ball R.H., Nyberg D.A., Comstock C.H., Saade G.R., Eddleman K.A., Klugman S., Dugoff L. Impact of maternal age on obstetric outcome. Obstetrics and Gynecology 2005, 105:983-990.
4. Cohen W.R., Newman L., Friedman E.A. Risks of labor abnormalities with advancing maternal age. Obstetrics and Gynecology 1980, 55:414-416.
5. Curley M., Cairns M.T., Friel A.M., McMeel O.M., Morrison J.J., Smith T.J. Expression of mRNA transcripts for ATP-sensitive potassium channels in human myometrium. Molecular Human Reproduction 2002, 8:941-945.
6. Du Q., Jovanović S., Clelland A., Sukhodub A., Budas G.R., Phelan K., Murray-Tait V., Malone L., Jovanović A. Overexpression of SUR2A generates a cardiac phenotype resistant to ischaemia. The FASEB Journal 2006, 20:1131-1141.
7. + channels. Human Reproduction 2010, 25:2774-2782.
8. ATP channels activity. Biochimica et Biophysica Acta: Molecular Cell Research 2010, 1803:405-415.
9. ATP channels: recent insights to energy sensing and myoprotection. Physiological Reviews 2010, 90:799-829.
10. Fox N.S., Rebarber A., Dunham S.M., Saltzman D.H. Outcomes of multiple gestations with advanced maternal age. Journal of Maternal-Fetal and Neonatal Medicine 2009, 22:593-596.
11. Heffner L., Elkin E., Fretts R. Impact on labor induction, gestational age, and maternal age on caesarean delivery rates. Obstetrics and Gynecology 2003, 102:287-293.
12. Jolly M., Sebire N., Harris J., Regan L. The risks associated with pregnancy in women aged 35 years or older. Human Reproduction 2000, 15:2433-2437.
13. ATP channels mediates cytoprotection in heart embryonic H9C2 cells. The International Journal of Biochemistry and Cell Biology 2009, 41:2295-2301.
14. Jovanović S., Du Q., Sukhodub A., Jovanović A. Dual mechanism of cytoprotection afforded by M-LDH in embryonic heart H9C2 cells. Biochimica et Biophysica Acta: Molecular Cell Research 2009, 1793:1379-1386.
15. + channels. Clinical and Translational Science 2008, 1:71-74.
16. Longo M., Jain V., Vedernikov Y.P., Hankins G.D., Garfield R.E., Saade G.R. Effects of L-type Ca(2+)-channel blockade, K(+)(ATP)-channel opening and nitric oxide on human uterine contractility in relation to gestational age and labour. Molecular Human Reproduction 2003, 9:159-164.
17. ATP channels as molecular sensors of cellular metabolism. Nature 2006, 440:470-476.
18. + channels in a gender-dependent manner. Mechanisms of Ageing and Development 2002, 123:695-705.
19. ATP channel subunits. European Journal of Obstetrics and Gynecology and Reproductive Biology 2005, 122:49-56.
20. Sudhir R., Sukhodub A., Du Q., Jovanović S., Jovanović A. Ageing-induced decline in physical endurance in mice is associated with decrease in cardiac SUR2A and increase in cardiac susceptibility to metabolic stress: therapeutic prospects for up-regulation of SUR2A. Biogerontology 2011, 12:147-155.
21. Sukhodub A., Du Q., Jovanović S., Jovanović A. Nicotinamide-rich diet protects the heart against ischaemia-reperfusion in mice: a crucial role for cardiac SUR2A. Pharmacological Research 2010, 61:564-570.
22. Sukhodub A., Sudhir R., Du Q., Jovanović S., Reyes S., Jovanović A. Nicotinamide-rich diet improves physical endurance by upregulating SUR2A in the heart. Journal of Cellular and Molecular Medicine 2011, 15:1703-1712.
23. Xu C., You X., Gao L., Zhang L., Hu R., Hui N., Olson D.M., Ni X. Expression of ATP-sensitive potassium channels in human pregnant myometrium. Reproductive Biology and Endocrinology 2011, 9:35.
24. Zasloff E., Schytt E., Waldenstrom U. First time mothers' pregnancy and birth experiences varying by age. Acta Obstetrica et Gynecologica Scandinavica 2007, 86:1328-1336.