Nicotinamide-rich diet protects the heart against ischaemia-reperfusion in mice: A crucial role for cardiac SUR2A

Pharmacological Research

Volumn 61, Issue 6, 2010, Pages 564-570

  Sukhodub, Andriy ^a   Du, Qingyou ^a   Jovanović, Sofija ^a   Jovanović, Aleksandar ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

Ischaemia; KATP channels; Nicotinamide; SUR2A

Indexed keywords

CLAMIKALANT; NICOTINAMIDE; POTASSIUM CHANNEL; PROTEIN SUR2A; TRIPHENYLTETRAZOLIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHANNEL GATING; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DIETARY INTAKE; DISEASE RESISTANCE; DRUG TARGETING; EXPERIMENTAL MOUSE; GENE OVEREXPRESSION; HEART; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HYPOXIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK REDUCTION; TRANSGENIC MOUSE; UPREGULATION; WILD TYPE;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CARDIOTONIC AGENTS; KATP CHANNELS; MALE; MICE; MICE, INBRED C57BL; MYOCARDIAL REPERFUSION INJURY; NIACINAMIDE; POTASSIUM CHANNELS, INWARDLY RECTIFYING; RECEPTORS, DRUG; RNA, MESSENGER;

EID: 77952885136     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2010.01.008     Document Type: Article

References (27)

1. + channels in cardiac muscle. Nature 1983, 305:147-148.
2. + channels. Neuron 1996, 16:1011-1017.
3. Cui Y., Giblin J.P., Clapp L.H., Tinker A. A mechanism for ATP-sensitive potassium channel diversity: functional coassembly of two pore-forming subunits. Proc Natl Acad Sci USA 2001, 98:729-734.
4. Carrasco A.J., Dzeja P.P., Alekseev A.E., Pucar D., Zingman L.V., Abraham M.R., et al. Adenylate kinase phosphotransfer communicates cellular energetic signals to ATP-sensitive potassium channels. Proc Acad Natl Sci USA 2001, 98:7623-7628.
5. + channel in vivo. FASEB J 2002, 16:102-104.
6. ATP channel subunit essential for cell protection against ischemia. EMBO J 2002, 21:3936-3948.
7. ATP channels via 1,3-bisphosphoglycerate: a novel link between cardiac membrane excitability and glucose metabolism. Diabetes 2005, 54:383-393.
8. ATP channel. EMBO Rep 2005, 6:848-852.
9. Murry C.E., Jennings R.B., Reimer K.A. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 1986, 74:1124-1136.
10. ATP channels and an overview of alternative mechanisms. J Mol Cell Cardiol 2005, 39:17-50.
11. Du Q., Jovanović S., Clelland A., Sukhodub A., Budas G.R., Phelan K., et al. Overexpression of SUR2A generates a cardiac phenotype resistant to ischaemia. FASEB J 2006, 20:1131-1141.
12. + channels. J Biol Chem 2003, 278:31444-31455.
13. + channels. J Am Coll Cardiol 2001, 38:906-915.
14. ATP channels in heart-derived H9c2 cells. J Am Coll Cardiol 2002, 40:367-374.
15. Jackson T.M., Rawling J.M., Roebuck B.D., Kirkland J.B. Large supplements of nicotinic acid and nicotinamide increase tissue NAD+ and poly(ADP-ribose) levels but do not affect diethylnitrosamine-induced altered hepatic foci in Fischer-344 rats. J Nutr 1995, 125:1455-1461.
16. 2α in the rat heart. Prostaglandins Other Lipid Mediat 2006, 80:110-119.
17. Pfaffl M.W. A new mathematical model for relative quantification in real time RT-PCR. Nucleic Acid Res 2001, 29:2002-2007.
18. Budas G.R., Sukhodub A., Alessi D.R., Jovanović A. 3′-Phosphoinositide-dependent kinase-1 (PDK1) is essential for ischaemic preconditioning of the myocardium. FASEB J 2006, 20:2556-2558.
19. 2+ protects adult beating cardiomyocytes against ischaemia. Int J Mol Med 2008, 21:69-73.
20. + channels. J Cell Physiol 2007, 210:224-236.
21. ATP channels. FASEB J 2004, 18:1046-1048.
22. Jovanović S., Du Q., Sukhodub A., Jovanović A. Dual mechanism of cytoprotection afforded by M-LDH in embryonic heart H9C2 cells. BBA-Mol Cell Res 2009, 1793:1379-1386.
23. ATP channels mediates cytoprotection in heart embryonic H9C2 cells. Int J Biochem Cell Biol 2009, 41:2295-2301.
24. Jovanović A., Jovanović S. SUR2A targeting for cardioprotection?. Curr Opin Pharmacol 2009, 9:189-193.
25. Vosper H. Niacin: a re-emerging pharmaceutical for the treatment of dyslipidaemia. Br J Pharmacol 2009, 158:429-441.
26. Bogan K.L., Brenner C. Nicotinic acid, nicotinamide, and nicotinamide riboside: a molecular evaluation of NAD+ precursor vitamins in human nutrition. Annu Rev Nutr 2008, 28:115-130.
27. Swain R., Kaplan B. Vitamins as therapy in 1990s. J Am Board Fam Pract 1995, 8:206-216.