Liver manipulation during liver surgery in humans is associated with hepatocellular damage and hepatic inflammation

Liver International

Volumn 33, Issue 4, 2013, Pages 633-641

  van den Broek, Maartje A J ^a   Shiri Sverdlov, Ronit ^b   Schreurs, Joris J W ^a   Bloemen, Johanne G ^a,c   Bieghs, Veerle ^b   Rensen, Sander S ^a,c   Dejong, Cornelis H C ^a,c   Olde Damink, Steven W M ^a,c,d  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c MAASTRICHT UNIVERSITY   (Netherlands)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Anterior approach; Hepatocellular damage; Inflammatory response; Liver mobilization; Liver surgery

Indexed keywords

ALANINE AMINOTRANSFERASE; CHEMOATTRACTANT; CHLORDANE; FATTY ACID BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MYELOPEROXIDASE; VASCULAR CELL ADHESION MOLECULE 1;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; CLINICAL ARTICLE; FEMALE; GENE EXPRESSION; HEPATITIS; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER BIOPSY; LIVER CELL DAMAGE; LIVER SURGERY; MALE; OBSERVATIONAL STUDY; PLASMA; UPREGULATION;

ALANINE TRANSAMINASE; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, MYELOMONOCYTIC; APOPTOSIS; BIOLOGICAL MARKERS; BIOPSY; CYTOKINES; DIGESTIVE SYSTEM SURGICAL PROCEDURES; FATTY ACID-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION; HEPATITIS; HUMANS; IMMUNOHISTOCHEMISTRY; INFLAMMATION MEDIATORS; LIVER; MALE; MIDDLE AGED; PEROXIDASE; TREATMENT OUTCOME; WOUNDS AND INJURIES;

EID: 84875051007     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12051     Document Type: Article

References (37)

1. van den Broek MA, Olde Damink SW, Dejong CH, et al. Liver failure after partial hepatic resection: definition, pathophysiology, risk factors and treatment. Liver Int 2008; 28: 767-780.
2. Kooby DA, Stockman J, Ben-Porat L, et al. Influence of transfusions on perioperative and long-term outcome in patients following hepatic resection for colorectal metastases. Ann Surg 2003; 237: 860-869.
3. van de Poll MC, Derikx JP, Buurman WA, et al. Liver manipulation causes hepatocyte injury and precedes systemic inflammation in patients undergoing liver resection. World J Surg 2007; 31: 2033-2038.
4. Chouker A, Martignoni A, Schauer RJ, et al. Alpha-gluthathione S-transferase as an early marker of hepatic ischemia/reperfusion injury after liver resection. World J Surg 2005; 29: 528-534.
5. van den Broek MA, Bloemen JG, Dello SA, et al. Randomized controlled trial analyzing the effect of 15 or 30 min intermittent Pringle maneuver on hepatocellular damage during liver surgery. J Hepatol 2011; 55: 337-345.
6. van de Poll MC, Hanssen SJ, Berbee M, et al. Elevated plasma arginase-1 does not affect plasma arginine in patients undergoing liver resection. Clin Sci (Lond) 2008; 114: 231-241.
7. Liu CL, Fan ST, Cheung ST, et al. Anterior approach versus conventional approach right hepatic resection for large hepatocellular carcinoma: a prospective randomized controlled study. Ann Surg 2006; 244: 194-203.
8. Schemmer P, Schoonhoven R, Swenberg JA, Bunzendahl H, Thurman RG. Gentle in situ liver manipulation during organ harvest decreases survival after rat liver transplantation: role of Kupffer cells. Transplantation 1998; 65: 1015-1020.
9. Schemmer P, Bunzendahl H, Raleigh JA, Thurman RG. Graft survival is improved by hepatic denervation before organ harvesting. Transplantation 1999; 67: 1301-1307.
10. Schemmer P, Enomoto N, Bradford BU, et al. Autonomic nervous system and gut-derived endotoxin: involvement in activation of Kupffer cells after in situ organ manipulation. World J Surg 2001; 25: 399-406.
11. Schemmer P, Connor HD, Arteel GE, et al. Reperfusion injury in livers due to gentle in situ organ manipulation during harvest involves hypoxia and free radicals. J Pharmacol Exp Ther 1999; 290: 235-240.
12. Couchoud C, Pozet N, Labeeuw M, Pouteil-Noble C. Screening early renal failure: cut-off values for serum creatinine as an indicator of renal impairment. Kidney Int 1999; 55: 1878-1884.
13. Strasberg SM. Nomenclature of hepatic anatomy and resections: a review of the Brisbane 2000 system. J Hepatobiliary Pancreat Surg 2005; 12: 351-355.
14. van den Broek MA, van Dam RM, van Breukelen GJ, et al. Development of a composite endpoint for randomized controlled trials in liver surgery. Br J Surg 2011; 98: 1138-1145.
15. van Dam RM, Hendry PO, Coolsen MM, et al. Initial experience with a multimodal enhanced recovery programme in patients undergoing liver resection. Br J Surg 2008; 95: 969-975.
16. Pelsers MM, Morovat A, Alexander GJ, et al. Liver fatty acid-binding protein as a sensitive serum marker of acute hepatocellular damage in liver transplant recipients. Clin Chem 2002; 48: 2055-2057.
17. Glatz JF, van der Vusse GJ. Cellular fatty acid-binding proteins: their function and physiological significance. Prog Lipid Res 1996; 35: 243-282.
18. Rensen SS, Slaats Y, Nijhuis J, et al. Increased hepatic myeloperoxidase activity in obese subjects with nonalcoholic steatohepatitis. Am J Pathol 2009; 175: 1473-1482.
19. Scatton O, Zalinski S, Jegou D, et al. Randomized clinical trial of ischaemic preconditioning in major liver resection with intermittent Pringle manoeuvre. Br J Surg 2011; 98: 1236-1243.
20. Petrowsky H, McCormack L, Trujillo M, et al. A prospective, randomized, controlled trial comparing intermittent portal triad clamping versus ischemic preconditioning with continuous clamping for major liver resection. Ann Surg 2006; 244: 921-928.
21. Sugiyama Y, Ishizaki Y, Imamura H, et al. Effects of intermittent Pringle's manoeuvre on cirrhotic compared with normal liver. Br J Surg 2010; 97: 1062-1069.
22. de Jonge WJ, The FO, van der Coelen D, et al. Mast cell degranulation during abdominal surgery initiates postoperative ileus in mice. Gastroenterology 2004; 127: 535-545.
23. Mantovani A, Sica A, Locati M. New vistas on macrophage differentiation and activation. Eur J Immunol 2007; 37: 14-16.
24. Ramaiah SK, Jaeschke H. Role of neutrophils in the pathogenesis of acute inflammatory liver injury. Toxicol Pathol 2007; 35: 757-766.
25. Nathan C. Points of control in inflammation. Nature 2002; 420: 846-852.
26. Schemmer P, Schoonhoven R, Swenberg JA, et al. Gentle organ manipulation during harvest as a key determinant of survival of fatty livers after transplantation in the rat. Transpl Int 1999; 12: 351-359.
27. The FO, Bennink RJ, Ankum WM, et al. Intestinal handling-induced mast cell activation and inflammation in human postoperative ileus. Gut 2008; 57: 33-40.
28. The FO, Buist MR, Lei A, et al. The role of mast cell stabilization in treatment of postoperative ileus: a pilot study. Am J Gastroenterol 2009; 104: 2257-2266.
29. The FO, de Jonge WJ, Bennink RJ, van den Wijngaard RM, Boeckxstaens GE. The ICAM-1 antisense oligonucleotide ISIS-3082 prevents the development of postoperative ileus in mice. Br J Pharmacol 2005; 146: 252-258.
30. Lai EC, Fan ST, Lo CM, Chu KM, Liu C. Anterior approach for difficult major right hepatectomy. World J Surg 1996; 20: 314-318.
31. Fan ST. Protection of the liver during partial hepatectomy. Hepatobiliary Pancreat Dis Int 2004; 3: 490-494.
32. Schemmer P, Barro-Bejarano M, Mehrabi A, et al. Laparoscopic organ retrieval for living donor liver transplantation does not prevent graft injury. Transplant Proc 2005; 37: 1625-1627.
33. Nsadi B, Gilson N, Pire E, et al. Consequences of pneumoperitoneum on liver ischemia during laparoscopic portal triad clamping in a swine model. J Surg Res 2011; 166: e35-e43.
34. Belghiti J, Guevara OA, Noun R, Saldinger PF, Kianmanesh R. Liver hanging maneuver: a safe approach to right hepatectomy without liver mobilization. J Am Coll Surg 2001; 193: 109-111.
35. DeLeve LD, Wang X, Kanel GC, et al. Decreased hepatic nitric oxide production contributes to the development of rat sinusoidal obstruction syndrome. Hepatology 2003; 38: 900-908.
36. Mehrabi A, Golling M, Busch C, et al. Experimental monitoring of hepatic glucose, lactate, and glutamate metabolism by microdialysis during surgical preparation of the liver hilus. J Surg Res 2002; 105: 128-135.
37. van den Broek MA, van Dam RM, Malago M, et al. Feasibility of randomized controlled trials in liver surgery using surgery-related mortality or morbidity as endpoint. Br J Surg 2009; 96: 1005-1014.