Synthesis and biological activities of some novel aminomethyl derivatives of 4-substituted-5-(2-thienyl)-2,4-dihydro-3H-1,2,4-triazole-3-thiones

European Journal of Medicinal Chemistry

Volumn 63, Issue , 2013, Pages 340-346

  Koparir, Metin ^a   Orek, Cahit ^a   Parlak, Akif Evren ^a   Söylemez, Abdurrazak ^a   Koparir, Pelin ^b   Karatepe, Mustafa ^a   Dastan, Sevgi Durna ^c  

^a FIRAT UNIVERSITY   (Turkey)

^b Department of Chemistry   (Turkey)

^c CUMHURIYET UNIVERSITY   (Turkey)

Author keywords

4 Substituted 5 (2 thienyl) 2,4 dihydro 3H 1,2,4 triazole 3 thiones; Biological activity; Mannich bases

Indexed keywords

1,2,4 TRIAZOLE DERIVATIVE; 2 (MORPHOLIN 4 YLMETHYL) 4 PHENYL 5 (2 THIENYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 2 [(4 BENZYLPIPERAZIN 1 YL)METHYL] 4 ETHYL 5 (2 THIENYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 2 [(4 METHYLPIPERIDIN 1 YL)METHYL] 4 PHENYL 5 (2 THIENYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 2 [(DIPROPYLAMINO)METHYL] 4 PHENYL 5 (2 THIENYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 ALLYL 2 (MORPHOLIN 4 YLMETHYL) 5 (2 THIENYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 ALLYL 2 [(4 METHYLPIPERIDIN 1 YL)METHYL] 5 (2 THIENYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 ALLYL 2 [(4 PHENYLPIPERAZIN 1 YL)METHYL] 5 (2 THIENYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 ALLYL 5 (2 THIENYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 ETHYL 2 (MORPHOLIN 4 YLMETHYL) 5 (2 THIENYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 ETHYL 2 [(4 METHYLPIPERIDIN 1 YL)METHYL] 5 (2 THIENYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 ETHYL 2 [(4 PHENYLPIPERAZIN 1 YL)METHYL] 5 (2 THIENYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 ETHYL 5 (2 THIENYL) 2 [[4 [3 (TRIFLUOROMETHYL)PHENYL]PIPERAZIN 1 YL]METHYL] 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 ETHYL 5 (2 THIENYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; 4 PHENYL 5 (2 THIENYL) 2,4 DIHYDRO 3H 1,2,4 TRIAZOLE 3 THIONE; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; NONHUMAN; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; ANTIOXIDANTS; ASPERGILLUS FLAVUS; ASPERGILLUS FUMIGATUS; BIPHENYL COMPOUNDS; DOSE-RESPONSE RELATIONSHIP, DRUG; ESCHERICHIA COLI; FREE RADICAL SCAVENGERS; MICROBIAL SENSITIVITY TESTS; MODELS, CHEMICAL; MOLECULAR STRUCTURE; OXIDATION-REDUCTION; PENICILLIUM; PICRATES; STAPHYLOCOCCUS AUREUS; THIONES; TRIAZOLES; TRICHOPHYTON;

EID: 84875040109     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.02.025     Document Type: Article

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