Both endonucleolytic and exonucleolytic cleavage mediate ITS1 removal during human ribosomal RNA processing

Journal of Cell Biology

Volumn 200, Issue 5, 2013, Pages 577-588

  Sloan, Katherine E ^a   Mattijssen, Sandy ^b,c   Lebaron, Simon ^d   Tollervey, David ^d   Pruijn, Ger J M ^b,c   Watkins, Nicholas J ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c RADBOUD UNIVERSITY NIJMEGEN   (Netherlands)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; EXONUCLEASE; INTERNAL TRANSCRIBED SPACER 1; RIBONUCLEASE; RIBOSOME PROTEIN; RIBOSOME RNA; RRP6 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BIOGENESIS; CARCINOGENESIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MECHANISM; EXOSOME; GENE LOCUS; GENE SILENCING; GENETIC DISORDER; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; RIBOSOME; RIBOSOMOPATHY; RNA CLEAVAGE; RNA PROCESSING; YEAST;

ENDORIBONUCLEASES; EXORIBONUCLEASES; EXOSOME MULTIENZYME RIBONUCLEASE COMPLEX; HEK293 CELLS; HELA CELLS; HUMANS; PROTEINS; RIBOSOMES; RNA INTERFERENCE; RNA PRECURSORS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, FUNGAL; RNA, RIBOSOMAL; RNA, RIBOSOMAL, 18S; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSFECTION;

EID: 84874994356     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201207131     Document Type: Article

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