Structured approach to the elicitation of expert beliefs for a Bayesian-designed clinical trial: A case study

Pharmaceutical Statistics

Volumn 12, Issue 2, 2013, Pages 104-113

  Kinnersley, Nelson ^a   Day, Simon ^a  

^a ROCHE PRODUCTS LTD   (United Kingdom)

Author keywords

Bayesian; beliefs; elicitation; expert opinion; feasibility

Indexed keywords

ARTICLE; BAYES THEOREM; CASE STUDY; CLINICAL PHARMACOLOGY; CONTROLLED STUDY; DATA COLLECTION METHOD; DRUG DEVELOPMENT; ELICITATION; FEASIBILITY STUDY; PROBABILITY; RANDOMIZED CONTROLLED TRIAL (TOPIC); RELIABILITY; STATISTICAL MODEL; STUDY DESIGN; SYSTEMATIC REVIEW (TOPIC); UNCERTAINTY; VALIDITY;

BAYES THEOREM; CLINICAL TRIALS AS TOPIC; CULTURE; FEASIBILITY STUDIES; HUMANS; RESEARCH PERSONNEL;

EID: 84874977112     PISSN: 15391604     EISSN: 15391612     Source Type: Journal    
DOI: 10.1002/pst.1552     Document Type: Article

References (45)

1. Ashby D,. Bayesian statistics in medicine: a 25 year review. Statistics in Medicine 2006; 25 (21): 3589-3631.
2. Berry DA,. A case for Bayesianism in clinical trials. Statistics in Medicine 1993; 12 (15-16): 1377-1393.
3. Grieve AP,. 25 years of Bayesian methods in the pharmaceutical industry: a personal, statistical bummel. Pharmaceutical Statistics 2007; 6 (4): 261-281.
4. Senn S,. Consensus and controversy in pharmaceutical statistics. Journal of the Royal Statistical Society: Series D (The Statistician) 2000; 49 (2): 135.
5. Spiegelhalter DJ, Abrams KR, Myles JP,. Bayesian approaches to clinical trials and health-care evaluation. John Wiley and Sons: Chichester, UK, 2004.
6. Whitehead J,. The case for frequentism in clinical trials. Statistics in Medicine 1993; 12 (15-16): 1405-1413.
7. O'Hagan A, Buck CE, Daneshkhah A, Eiser JR, Garthwaite PH, Jenkinson DJ, Oakley JE, Rakow T,. Uncertain judgements: eliciting experts' probabilities. John Wiley and Sons: Chichester, UK, 2006.
8. Albert I, Donnet S, Guihenneuc-Jouyaux C, Low-Choy S, Mengersen K, Rousseau J,. Combining expert opinions in prior elicitation. Bayesian Analysis 2012; 7 (3): 503-532.
9. Spiegelhalter DJ, Freedman LS, Parmar MKB,. Bayesian approaches to randomized trials. Journal of the Royal Statistical Society. Series A (Statistics in Society). 1994; 157 (3): 357-416.
10. Cornfield J,. Sequential trials, sequential analysis and the likelihood principle. The American Statistician 1966; 20 (2): 18-23.
11. Neuenschwander B, Capkun-Niggli G, Branson M, Spiegelhalter DJ,. Summarizing historical information on controls in clinical trials. Clinical Trials 2010; 7 (1): 5-18.
12. Pocock SJ,. The combination of randomized and historical controls in clinical trials. Journal of Chronic Diseases (1976) 29 (3): 175-188.
13. Whitehead J, Valdés-Márquez E, Johnson P, Graham G,. (2008) Bayesian sample size for exploratory clinical trials incorporating historical data. Statistics in Medicine 2008; 27 (13): 2307-2327.
14. Whitehead J,. Using Bayesian decision theory in dose-escalation studies. In Statistical Methods for Dose-Finding Experiments., Chevret S, (ed.). John Wiley and Sons: Chichester, UK, 2006.
15. Etzioni R, Kadane JB,. Optimal experimental design for another's analysis. Journal of the American Statistical Association 1993; 88 (424): 1404-1411.
16. Whitehead J, Williamson D,. Bayesian decision procedures based on logistic regression models for dose-finding studies. Journal of Biopharmaceutical Statistics 1998; 8 (3): 445-467.
17. Johnson SR, Tomlinson GA, Hawker GA, Granton JT, Feldman BM,. Methods to elicit beliefs for Bayesian priors: a systematic review. Journal of Clinical Epidemiology 2010; 63 (4): 355-369.
18. Morita S,. Application of the continual reassessment method to a phase I dose-finding trial in Japanese patients: East meets West. Statistics in Medicine 2011; 30 (17): 2090-2097.
19. Kynn M,. The 'heuristics and biases' bias in expert elicitation. Journal of the Royal Statistical Society. Series A (Statistics in Society). 2008; 171 (1): 239-264.
20. Morris P,. Decision analysis expert use. Management Science 1974; 10 (9): 1233-1241.
21. Kadane JB,. Progress toward a more ethical method for clinical trials. Journal of Medicine and Philosophy 1986; 11 (4): 385-404.
22. Blanck T, Conahan T, Merin R, Prager R, Richter J,. Being an expert. In Bayesian Methods and Ethics in a Clinical Trial Design., Kadane JB, (ed.). John Wiley & Sons, Inc.: New York, 1996.
23. Myung IJ, Ramamoorti S, Bailey A,. Maximum entropy aggregation of expert predictions. Management Science 1996; 42 (10): 1420-1436.
24. Garthwaite PH, Kadane JB, O'Hagan A,. Statistical methods for eliciting probability distributions. Journal of the American Statistical Association 2005; 100 (470): 680-701.
25. Cooke RM, Goossens LHJ,. Procedures guide for structural expert judgement in accident consequence modelling. Radiation Protection Dosimetry 2000; 90 (3): 303-309.
26. Hardaker JB, Lien G,. Towards Some Principles of Good Practice for Decision Analysis in Agriculture. Norwegian Agriculture Economics Research Institute: Oslo, 2005. Available at: http://www.nilf.no/publikasjoner/Notater/ 2005/Towards-some-principles-of-good-practice-for-decision-analysis-in- agriculture-Contents (accessed 20 June 2011).
27. Choy SL, O'Leary R, Mengersen K,. Elicitation by design in ecology: using expert opinion to inform priors for Bayesian statistical models. Ecology 2009; 90 (1): 265-277.
28. Kuhnert P, Martin T, Griffiths S,. A guide to eliciting and using expert knowledge in Bayesian ecological models. Ecology Letters 2010; 13 (7): 900-914.
29. Lunn DJ, Thomas A, Best N, Spiegelhalter D,. WinBUGS-a Bayesian modelling framework: concepts, structure, and extensibility. Statistics and Computing 2000; 10 (4): 325-337.
30. Oakley JE, O'Hagan A,. SHELF: the Sheffield Elicitation Framework (version 2.0), 2010. Available at: http://www.tonyohagan.co.uk/shelf/ (accessed 2 May 2011).
31. Kahneman D,. Thinking, fast and slow. Allen Lane: London, 2011.
32. Kadane J, Wolfson LJ,. Experiences in elicitation. Journal of the Royal Statistical Society: Series D (The Statistician) 1998; 47 (1): 3-19.
33. Kottner J, Audige L, Brorson S, Donner A, Gajewski BJ, Hrobjartsson A, Roberts C, Shoukri M, Streiner DL,. Guidelines for reporting reliability and agreement studies (GRRAS) were proposed. International Journal of Nursing Studies 2011; 48 (6): 661-671.
34. Anderson JJ, Baron G, Van DH D, Felson DT, Dougados M,. Ankylosing spondylitis assessment group preliminary definition of short-term improvement in ankylosing spondylitis. Arthritis & Rheumatism 2001; 44 (8): 1876-1886.
35. Morita S, Thall PF, Müller P,. Determining the effective sample size of a parametric prior. Biometrics 2008; 64 (2): 595-602.
36. O'Hagan A,. Dicing with the unknown. Significance 2004; 1 (3): 132-133.
37. Gore SM,. Biostatistics and the Medical Research Council. Medical Research Council News 1987; 35: 19-21.
38. Johnson SR, Tomlinson GA, Hawker GA, Granton JT, Grosbein HA, Feldman BM,. A valid and reliable belief elicitation method for Bayesian priors. Journal of Clinical Epidemiology 2010; 63 (4): 370-383.
39. Johnson SR, Granton JT, Tomlinson GA, Grosbein HA, Hawker GA, Feldman B,. Effect of warfarin on survival in scleroderma-associated pulmonary arterial hypertension (SSc-PAH) and idiopathic PAH. Belief elicitation for Bayesian priors. Journal of Rheumatology 2011; 38 (3): 462-469.
40. R Development Core Team. R: A Language and Environment for Statistical Computing. R Foundation for Statistical Computing: Vienna, Austria, 2011. Available at: http://www.R-project.org/ (accessed 2 May 2011).
41. Tan S-B, Chung Y-F, Tai B-C, Cheung Y-B, Machin D,. Elicitation of prior distributions for a phase III randomized controlled trial of adjuvant therapy with surgery for hepatocellular carcinoma. Controlled Clinical Trials 2003; 24 (2): 110-121.
42. Teigen KH, Jorgensen M,. When 90% confidence intervals are 50% certain: on the credibility of credible intervals. Applied Cognitive Psychology 2005; 19 (4): 455-475.
43. McCulloch CE, Searle SR, Neuhaus JM,. Generalized, linear, and mixed models. John Wiley and Sons: Chichester, UK, 2011.
44. Yin G, Yuan Y,. Bayesian model averaging continual reassessment method in phase I clinical trials. Journal of the American Statistical Association 2009; 104 (487): 954-968.
45. Gosling JP, Oakley JE, O'Hagan A,. Nonparametric elicitation for heavy-tailed prior distributions. Bayesian Analysis 2007; 2 (4): 693-718.