Empiric antibiotics and outcomes of children hospitalized with eczema herpeticum

Pediatric Dermatology

Volumn 30, Issue 2, 2013, Pages 207-214

  Aronson, Paul L ^a,b   Yan, Albert C ^a,b,c   Mohamad, Zeinab ^a   Mittal, Manoj K ^a,b   Shah, Samir S ^d,e  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^e UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; AMCINONIDE; AMOXICILLIN PLUS CLAVULANIC ACID; ANTIBIOTIC AGENT; BACITRACIN; CALCINEURIN INHIBITOR; CEPHALOSPORIN; CLINDAMYCIN; CLOBETASOL; CLOXACILLIN; CORTICOSTEROID; COTRIMOXAZOLE; DEXAMETHASONE; DICLOXACILLIN; FLUTICASONE; LINEZOLID; METHYLPREDNISOLONE; MOMETASONE FUROATE; NAFCILLIN; NEOMYCIN; OXACILLIN; PIPERACILLIN PLUS TAZOBACTAM; PREDNISOLONE; PSEUDOMONIC ACID; SULTAMICILLIN; TIMENTIN; TRIAMCINOLONE; UNINDEXED DRUG; VALACICLOVIR; VANCOMYCIN;

ADOLESCENT; ANTIBIOTIC THERAPY; ARTICLE; BLOODSTREAM INFECTION; CHILD; FEMALE; HOSPITALIZATION; HOSPITALIZED CHILD; HUMAN; INFANT; KAPOSI VARICELLIFORM ERUPTION; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; MORTALITY; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; STAPHYLOCOCCUS INFECTION;

ADOLESCENT; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; FEMALE; HOSPITALIZATION; HUMANS; INFANT; KAPOSI VARICELLIFORM ERUPTION; LENGTH OF STAY; MALE; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84874942251     PISSN: 07368046     EISSN: 15251470     Source Type: Journal    
DOI: 10.1111/j.1525-1470.2012.01860.x     Document Type: Article

References (26)

1. Laughter D, Istvan JA, Tofte SJ, et al., The prevalence of atopic dermatitis in Oregon schoolchildren. J Am Acad Dermatol 2000; 43: 649-655.
2. Bieber T,. Atopic dermatitis. N Engl J Med 2008; 358: 1483-1494.
3. Wollenberg A, Rawer HC, Schauber J,. Innate immunity in atopic dermatitis. Clin Rev Allergy Immunol 2011; 41: 272-281.
4. Gao PS, Rafaels NM, Hand T, et al., Filaggrin mutations that confer risk of atopic dermatitis confer greater risk for eczema herpeticum. J Allergy Clin Immunol 2009; 124: 507-513, 513.e1-7.
5. Howell MD, Wollenberg A, Gallo RL, et al., Cathelicidin deficiency predisposes to eczema herpeticum. J Allergy Clin Immunol 2006; 117: 836-841.
6. David TJ, Longson M,. Herpes simplex infections in atopic eczema. Arch Dis Child 1985; 60: 338-343.
7. Novelli VM, Atherton DJ, Marshall WC,. Eczema herpeticum: clinical and laboratory features. Clin Pediatr (Phila) 1988; 27: 231-233.
8. Lai YC, Shyur SD, Fu JL,. Eczema herpeticum in children with atopic dermatitis. Acta Paediatr Taiwan 1999; 40: 325-329.
9. Aronson PL, Yan AC, Mittal MK, et al., Delayed acyclovir and outcomes of children hospitalized with eczema herpeticum. Pediatrics 2011; 128: 1161-1167.
10. Brook I, Frazier EH, Yeager JK,. Microbiology of infected eczema herpeticum. J Am Acad Dermatol 1998; 38: 627-629.
11. Bork K, Brauninger W,. Increasing incidence of eczema herpeticum: analysis of seventy-five cases. J Am Acad Dermatol 1988; 19: 1024-1029.
12. Ingrand D, Briquet I, Babinet JM, et al., Eczema herpeticum of the child. An unusual manifestation of herpes simplex virus infection. Clin Pediatr (Phila) 1985; 24: 660-663.
13. Taieb A, Fontan I, Maleville J,. Acyclovir therapy for eczema herpeticum in infants. Arch Dermatol 1985; 121: 1380-1381.
14. Mongelluzzo J, Mohamad Z, Ten Have TR, et al., Corticosteroids and mortality in children with bacterial meningitis. JAMA 2008; 299: 2048-2055.
15. Shah SS, Hall M, Srivastava R, et al., Intravenous immunoglobulin in children with streptococcal toxic shock syndrome. Clin Infect Dis 2009; 49: 1369-1376.
16. Hughes J,. Development of the 3M™ All Patient Refined Diagnosis Related Groups (APR DRGs) [on-line]. Available at http://www.ahrq.gov/qual/ mortality/Hughes.htm. Accessed February 26, 2011.
17. Mickey RM, Greenland S,. The impact of confounder selection criteria on effect estimation. Am J Epidemiol 1989; 129: 125-137.
18. Concato J, Feinstein AR, Holford TR,. The risk of determining risk with multivariable models. Ann Intern Med 1993; 118: 201-210.
19. Van den Bruel A, Haj-Hassan T, Thompson M, et al., Diagnostic value of clinical features at presentation to identify serious infection in children in developed countries: a systematic review. Lancet 2010; 375: 834-845.
20. Brent AJ, Lakhanpaul M, Ninis N, et al., Evaluation of temperature-pulse centile charts in identifying serious bacterial illness: observational cohort study. Arch Dis Child 2011; 96: 368-373.
21. Leyden JJ, Marples RR, Kligman AM,. Staphylococcus aureus in the lesions of atopic dermatitis. Br J Dermatol 1974; 90: 525-530.
22. Aly R, Maibach HI, Shinefield HR,. Microbial flora of atopic dermatitis. Arch Dermatol 1977; 113: 780-782.
23. Breuer K, Haussler S, Kapp A, et al., Staphylococcus aureus: colonizing features and influence of an antibacterial treatment in adults with atopic dermatitis. Br J Dermatol 2002; 147: 55-61.
24. Suh L, Coffin S, Leckerman KH, et al., Methicillin-resistant Staphylococcus aureus colonization in children with atopic dermatitis. Pediatr Dermatol 2008; 25: 528-534.
25. Huang JT, Abrams M, Tlougan B, et al., Treatment of Staphylococcus aureus colonization in atopic dermatitis decreases disease severity. Pediatrics 2009; 123: e808-e814.
26. Matiz C, Tom WL, Eichenfield LF, et al., Children with atopic dermatitis appear less likely to be infected with community acquired methicillin-resistant Staphylococcus aureus: the San Diego experience. Pediatr Dermatol 2011; 28: 6-11.