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Volumn 49, Issue 5, 2013, Pages 1080-1089

CD4 lymphopenia to identify end-of-life metastatic cancer patients

Author keywords

Cancer; CD4 lymphocytes; Immunology; Lymphopenia; Survival analysis

Indexed keywords

ADULT; ADVANCED CANCER; ARTICLE; CANCER PATIENT; CANCER PROGNOSIS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; LIFE EXPECTANCY; LYMPHOCYTOPENIA; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; METASTASIS; MULTIVARIATE ANALYSIS; MYELOMA; OBSERVATIONAL STUDY; OVERALL SURVIVAL; PATIENT IDENTIFICATION; PHENOTYPE; PRIORITY JOURNAL; SURVIVAL RATE; TERMINAL CARE; VALIDATION STUDY;

EID: 84874941830     PISSN: 09598049     EISSN: 18790852     Source Type: Journal    
DOI: 10.1016/j.ejca.2012.11.003     Document Type: Article
Times cited : (35)

References (36)
  • 1
    • 0033558334 scopus 로고    scopus 로고
    • Increased TNF-alpha-induced apoptosis in lymphocytes from aged humans: Changes in TNF-alpha receptor expression and activation of caspases
    • S. Aggarwal, S. Gollapudi, and S. Gupta Increased TNF-alpha-induced apoptosis in lymphocytes from aged humans: changes in TNF-alpha receptor expression and activation of caspases J Immunol 162 1999 2154 2161
    • (1999) J Immunol , vol.162 , pp. 2154-2161
    • Aggarwal, S.1    Gollapudi, S.2    Gupta, S.3
  • 2
    • 0026625812 scopus 로고
    • Serum level of interleukin 6 as a prognosis factor in metastatic renal cell carcinoma
    • J.Y. Blay, S. Negrier, and V. Combaret Serum level of interleukin 6 as a prognosis factor in metastatic renal cell carcinoma Cancer Res 52 1992 3317 3322
    • (1992) Cancer Res , vol.52 , pp. 3317-3322
    • Blay, J.Y.1    Negrier, S.2    Combaret, V.3
  • 3
    • 0035292979 scopus 로고    scopus 로고
    • Decreased zeta chain expression and apoptosis in CD3+ peripheral blood T lymphocytes of patients with melanoma
    • G. Dworacki, N. Meidenbauer, and I. Kuss Decreased zeta chain expression and apoptosis in CD3+ peripheral blood T lymphocytes of patients with melanoma Clin Cancer Res 7 2001 947s 957s
    • (2001) Clin Cancer Res , vol.7
    • Dworacki, G.1    Meidenbauer, N.2    Kuss, I.3
  • 4
    • 0032979606 scopus 로고    scopus 로고
    • Spontaneous ex vivo apoptosis of peripheral blood mononuclear cells in patients with head and neck cancer
    • T. Saito, I. Kuss, and G. Dworacki Spontaneous ex vivo apoptosis of peripheral blood mononuclear cells in patients with head and neck cancer Clin Cancer Res 5 1999 1263 1273
    • (1999) Clin Cancer Res , vol.5 , pp. 1263-1273
    • Saito, T.1    Kuss, I.2    Dworacki, G.3
  • 5
    • 68949208658 scopus 로고    scopus 로고
    • Relationship between low lymphocyte count and major cardiac events in patients with acute chest pain, a non-diagnostic electrocardiogram and normal troponin levels
    • J. Nunez, J. Sanchis, and V. Bodi Relationship between low lymphocyte count and major cardiac events in patients with acute chest pain, a non-diagnostic electrocardiogram and normal troponin levels Atherosclerosis 206 2009 251 257
    • (2009) Atherosclerosis , vol.206 , pp. 251-257
    • Nunez, J.1    Sanchis, J.2    Bodi, V.3
  • 6
    • 0031924241 scopus 로고    scopus 로고
    • Clinical associations of lymphopenia in elderly persons admitted to acute medical and psychiatric wards
    • M.S. Dennis, A. Nicolson, and A.B. Lehmann Clinical associations of lymphopenia in elderly persons admitted to acute medical and psychiatric wards Gerontology 44 1998 168 171
    • (1998) Gerontology , vol.44 , pp. 168-171
    • Dennis, M.S.1    Nicolson, A.2    Lehmann, A.B.3
  • 7
    • 0032548107 scopus 로고    scopus 로고
    • A prognostic score for advanced Hodgkin's disease. International prognostic factors project on advanced Hodgkin's disease
    • D. Hasenclever, and V. Diehl A prognostic score for advanced Hodgkin's disease. International prognostic factors project on advanced Hodgkin's disease N Engl J Med 339 1998 1506 1514
    • (1998) N Engl J Med , vol.339 , pp. 1506-1514
    • Hasenclever, D.1    Diehl, V.2
  • 8
    • 33747387248 scopus 로고    scopus 로고
    • Absolute lymphocyte count predicts overall survival in follicular lymphomas
    • M. Siddiqui, K. Ristow, and S.N. Markovic Absolute lymphocyte count predicts overall survival in follicular lymphomas Br J Haematol 134 2006 596 601
    • (2006) Br J Haematol , vol.134 , pp. 596-601
    • Siddiqui, M.1    Ristow, K.2    Markovic, S.N.3
  • 9
    • 33846445664 scopus 로고    scopus 로고
    • Early lymphocyte recovery as a prognostic indicator for high-risk Ewing sarcoma
    • G. De Angulo, M. Hernandez, and J. Morales-Arias Early lymphocyte recovery as a prognostic indicator for high-risk Ewing sarcoma J Pediatr Hematol Oncol 29 2007 48 52
    • (2007) J Pediatr Hematol Oncol , vol.29 , pp. 48-52
    • De Angulo, G.1    Hernandez, M.2    Morales-Arias, J.3
  • 10
    • 67650481213 scopus 로고    scopus 로고
    • Lymphopenia as a prognostic factor for overall survival in advanced carcinomas, sarcomas, and lymphomas
    • I. Ray-Coquard, C. Cropet, and M. Van Glabbeke Lymphopenia as a prognostic factor for overall survival in advanced carcinomas, sarcomas, and lymphomas Cancer Res 69 2009 5383 5391
    • (2009) Cancer Res , vol.69 , pp. 5383-5391
    • Ray-Coquard, I.1    Cropet, C.2    Van Glabbeke, M.3
  • 11
    • 77954695842 scopus 로고    scopus 로고
    • Prognostic significance of early lymphocyte recovery in pediatric osteosarcoma
    • C. Moore, D. Eslin, and A. Levy Prognostic significance of early lymphocyte recovery in pediatric osteosarcoma Pediatr Blood Cancer 55 6 2010 1096 1102
    • (2010) Pediatr Blood Cancer , vol.55 , Issue.6 , pp. 1096-1102
    • Moore, C.1    Eslin, D.2    Levy, A.3
  • 12
    • 82455171887 scopus 로고    scopus 로고
    • Pre-treatment lymphopenia as a prognostic biomarker in colorectal cancer patients receiving chemotherapy
    • N. Ceze, G. Thibault, and G. Goujon Pre-treatment lymphopenia as a prognostic biomarker in colorectal cancer patients receiving chemotherapy Cancer Chemother Pharmacol 68 5 2011 1305 1313
    • (2011) Cancer Chemother Pharmacol , vol.68 , Issue.5 , pp. 1305-1313
    • Ceze, N.1    Thibault, G.2    Goujon, G.3
  • 13
    • 80051580303 scopus 로고    scopus 로고
    • Lymphopenia is an important prognostic factor in peripheral T-cell lymphoma (NOS) treated with anthracycline-containing chemotherapy
    • Y.R. Kim, J.S. Kim, and S.J. Kim Lymphopenia is an important prognostic factor in peripheral T-cell lymphoma (NOS) treated with anthracycline-containing chemotherapy J Hematol Oncol 4 2011 34
    • (2011) J Hematol Oncol , vol.4 , pp. 34
    • Kim, Y.R.1    Kim, J.S.2    Kim, S.J.3
  • 14
    • 0030058847 scopus 로고    scopus 로고
    • Early lymphopenia after cytotoxic chemotherapy as a risk factor for febrile neutropenia
    • J.Y. Blay, F. Chauvin, and A. Le Cesne Early lymphopenia after cytotoxic chemotherapy as a risk factor for febrile neutropenia J Clin Oncol 14 1996 636 643
    • (1996) J Clin Oncol , vol.14 , pp. 636-643
    • Blay, J.Y.1    Chauvin, F.2    Le Cesne, A.3
  • 15
    • 0042309568 scopus 로고    scopus 로고
    • Early lymphopenia as a risk factor for chemotherapy-induced febrile neutropenia
    • C.W. Choi, H.J. Sung, and K.H. Park Early lymphopenia as a risk factor for chemotherapy-induced febrile neutropenia Am J Hematol 73 2003 263 266
    • (2003) Am J Hematol , vol.73 , pp. 263-266
    • Choi, C.W.1    Sung, H.J.2    Park, K.H.3
  • 16
    • 31644436272 scopus 로고    scopus 로고
    • Which one is a risk factor for chemotherapy-induced febrile neutropenia in childhood solid tumors: Early lymphopenia or monocytopenia?
    • A. Oguz, C. Karadeniz, E.C. Ckitak, and V. Cil Which one is a risk factor for chemotherapy-induced febrile neutropenia in childhood solid tumors: early lymphopenia or monocytopenia? Pediatr Hematol Oncol 23 2006 143 151
    • (2006) Pediatr Hematol Oncol , vol.23 , pp. 143-151
    • Oguz, A.1    Karadeniz, C.2    Ckitak, E.C.3    Cil, V.4
  • 17
    • 0037468101 scopus 로고    scopus 로고
    • Baseline and early lymphopenia predict for the risk of febrile neutropenia after chemotherapy
    • I. Ray-Coquard, C. Borg, and T. Bachelot Baseline and early lymphopenia predict for the risk of febrile neutropenia after chemotherapy Br J Cancer 88 2003 181 186
    • (2003) Br J Cancer , vol.88 , pp. 181-186
    • Ray-Coquard, I.1    Borg, C.2    Bachelot, T.3
  • 18
    • 8844256062 scopus 로고    scopus 로고
    • CD4 lymphopenia as a risk factor for febrile neutropenia and early death after cytotoxic chemotherapy in adult patients with cancer
    • C. Borg, I. Ray-Coquard, and I. Philip CD4 lymphopenia as a risk factor for febrile neutropenia and early death after cytotoxic chemotherapy in adult patients with cancer Cancer 101 2004 2675 2680
    • (2004) Cancer , vol.101 , pp. 2675-2680
    • Borg, C.1    Ray-Coquard, I.2    Philip, I.3
  • 19
    • 17544395190 scopus 로고    scopus 로고
    • A risk model for thrombocytopenia requiring platelet transfusion after cytotoxic chemotherapy
    • J.Y. Blay, A. Le Cesne, and C. Mermet A risk model for thrombocytopenia requiring platelet transfusion after cytotoxic chemotherapy Blood 92 1998 405 410
    • (1998) Blood , vol.92 , pp. 405-410
    • Blay, J.Y.1    Le Cesne, A.2    Mermet, C.3
  • 20
    • 0032831011 scopus 로고    scopus 로고
    • Risk model for severe anemia requiring red blood cell transfusion after cytotoxic conventional chemotherapy regimens. The Elypse 1 Study Group
    • I. Ray-Coquard, A. Le Cesne, and M.T. Rubio Risk model for severe anemia requiring red blood cell transfusion after cytotoxic conventional chemotherapy regimens. The Elypse 1 Study Group J Clin Oncol 17 1999 2840 2846
    • (1999) J Clin Oncol , vol.17 , pp. 2840-2846
    • Ray-Coquard, I.1    Le Cesne, A.2    Rubio, M.T.3
  • 21
    • 84874931190 scopus 로고    scopus 로고
    • ELYPSE 2: A prospective randomized trial comparing filgrastim (G-CSF) in primary and secondary prophylaxis in patients (pts) at high risk for febrile neutropenia (FN) [2006 ASCO Annual Meeting Proceedings Part I]
    • P. Biron, I. Ray-Coquard, and A. Le Cesne ELYPSE 2: a prospective randomized trial comparing filgrastim (G-CSF) in primary and secondary prophylaxis in patients (pts) at high risk for febrile neutropenia (FN) [2006 ASCO Annual Meeting Proceedings Part I] J Clin Oncol 24 18S 2006 8614
    • (2006) J Clin Oncol , vol.24 , Issue.18 S , pp. 8614
    • Biron, P.1    Ray-Coquard, I.2    Le Cesne, A.3
  • 22
    • 66149103228 scopus 로고    scopus 로고
    • A risk model for severe anemia to select cancer patients for primary prophylaxis with epoetin alpha: A prospective randomized controlled trial of the ELYPSE study group
    • I. Ray-Coquard, S. Dussart, and C. Goillot A risk model for severe anemia to select cancer patients for primary prophylaxis with epoetin alpha: a prospective randomized controlled trial of the ELYPSE study group Ann Oncol 20 2009 1105 1112
    • (2009) Ann Oncol , vol.20 , pp. 1105-1112
    • Ray-Coquard, I.1    Dussart, S.2    Goillot, C.3
  • 23
    • 0035860126 scopus 로고    scopus 로고
    • Identification of patients at risk for early death after conventional chemotherapy in solid tumours and lymphomas
    • I. Ray-Coquard, H. Ghesquiere, and T. Bachelot Identification of patients at risk for early death after conventional chemotherapy in solid tumours and lymphomas Br J Cancer 85 2001 816 822
    • (2001) Br J Cancer , vol.85 , pp. 816-822
    • Ray-Coquard, I.1    Ghesquiere, H.2    Bachelot, T.3
  • 24
    • 56649121692 scopus 로고    scopus 로고
    • Low absolute lymphocyte count is a poor prognostic marker in patients with diffuse large B-cell lymphoma and suggests patients' survival benefit from rituximab
    • Y. Oki, K. Yamamoto, and H. Kato Low absolute lymphocyte count is a poor prognostic marker in patients with diffuse large B-cell lymphoma and suggests patients' survival benefit from rituximab Eur J Haematol 81 2008 448 453
    • (2008) Eur J Haematol , vol.81 , pp. 448-453
    • Oki, Y.1    Yamamoto, K.2    Kato, H.3
  • 25
    • 34547840267 scopus 로고    scopus 로고
    • Peripheral blood natural killer cell count is associated with clinical outcome in patients with aaIPI 2-3 diffuse large B-cell lymphoma
    • A. Plonquet, C. Haioun, and J.P. Jais Peripheral blood natural killer cell count is associated with clinical outcome in patients with aaIPI 2-3 diffuse large B-cell lymphoma Ann Oncol 18 2007 1209 1215
    • (2007) Ann Oncol , vol.18 , pp. 1209-1215
    • Plonquet, A.1    Haioun, C.2    Jais, J.P.3
  • 26
    • 33845382806 scopus 로고
    • Nonparametric estimation from incomplete observations
    • E.L. Kaplan, and P. Meier Nonparametric estimation from incomplete observations J Am Stat Assoc 53 1958 457 481
    • (1958) J Am Stat Assoc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 27
    • 0030069896 scopus 로고    scopus 로고
    • Multivariable prognostic models: Issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors
    • F.E. Harrell Jr., K.L. Lee, and D.B. Mark Multivariable prognostic models: issues in developing models, evaluating assumptions and adequacy, and measuring and reducing errors Stat Med 15 1996 361 387
    • (1996) Stat Med , vol.15 , pp. 361-387
    • Harrell, Jr.F.E.1    Lee, K.L.2    Mark, D.B.3
  • 29
    • 84874933736 scopus 로고    scopus 로고
    • Low TCR diversity (divpenia) is a new prognosis factor of overall survival in metastatic breast cancer
    • [abstract number: LB-165]
    • O.T. Manuarii Manuel, T. Bachelot, and T. Rabeony Low TCR diversity (divpenia) is a new prognosis factor of overall survival in metastatic breast cancer AACR 2011 [abstract number: LB-165]
    • (2011) AACR
    • Manuarii Manuel, O.T.1    Bachelot, T.2    Rabeony, T.3
  • 30
  • 32
    • 63449095686 scopus 로고    scopus 로고
    • Clinical and biological efficacy of recombinant human interleukin-21 in patients with stage IV malignant melanoma without prior treatment: A phase IIa trial
    • I.D. Davis, B. Brady, and R.F. Kefford Clinical and biological efficacy of recombinant human interleukin-21 in patients with stage IV malignant melanoma without prior treatment: a phase IIa trial Clin Cancer Res 15 2009 2123 2129
    • (2009) Clin Cancer Res , vol.15 , pp. 2123-2129
    • Davis, I.D.1    Brady, B.2    Kefford, R.F.3
  • 33
    • 79955418828 scopus 로고    scopus 로고
    • Harnessing the biology of IL-7 for therapeutic application
    • C.L. Mackall, T.J. Fry, and R.E. Gress Harnessing the biology of IL-7 for therapeutic application Nat Rev Immunol 11 5 2011 330 342
    • (2011) Nat Rev Immunol , vol.11 , Issue.5 , pp. 330-342
    • MacKall, C.L.1    Fry, T.J.2    Gress, R.E.3
  • 34
    • 52649088779 scopus 로고    scopus 로고
    • Ctla-4 blockade confers lymphocyte resistance to regulatory T-cells in advanced melanoma: Surrogate marker of efficacy of tremelimumab?
    • C. Menard, F. Ghiringhelli, and S. Roux Ctla-4 blockade confers lymphocyte resistance to regulatory T-cells in advanced melanoma: surrogate marker of efficacy of tremelimumab? Clin Cancer Res 14 2008 5242 5249
    • (2008) Clin Cancer Res , vol.14 , pp. 5242-5249
    • Menard, C.1    Ghiringhelli, F.2    Roux, S.3
  • 35
    • 84855859957 scopus 로고    scopus 로고
    • Differentiation therapy: Targeting human renal cancer stem cells with interleukin 15
    • S. Azzi, S. Bruno, and J. Giron-Michel Differentiation therapy: targeting human renal cancer stem cells with interleukin 15 J Natl Cancer Inst 103 24 2011 1884 1898
    • (2011) J Natl Cancer Inst , vol.103 , Issue.24 , pp. 1884-1898
    • Azzi, S.1    Bruno, S.2    Giron-Michel, J.3
  • 36
    • 79952558403 scopus 로고    scopus 로고
    • Validation of prognostic scores for survival in cancer patients beyond first-line therapy
    • O. Tredan, I. Ray-Coquard, and F. Chvetzoff Validation of prognostic scores for survival in cancer patients beyond first-line therapy BMC cancer 80 2011 5875 5885
    • (2011) BMC Cancer , vol.80 , pp. 5875-5885
    • Tredan, O.1    Ray-Coquard, I.2    Chvetzoff, F.3


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