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Volumn 26, Issue 2, 2013, Pages 159-167

Blood biomarkers for personalized treatment and patient management decisions in community-acquired pneumonia

Author keywords

Antibiotic stewardship; Biomarker; Community acquired pneumonia; Proadrenomedullin; Procalcitonin

Indexed keywords

ANTIBIOTIC AGENT; C REACTIVE PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; PROADRENOMEDULLIN; PROCALCITONIN; TUMOR NECROSIS FACTOR ALPHA;

EID: 84874939867     PISSN: 09517375     EISSN: 14736527     Source Type: Journal    
DOI: 10.1097/QCO.0b013e32835d0bec     Document Type: Review
Times cited : (55)

References (69)
  • 1
    • 80053284682 scopus 로고    scopus 로고
    • Guidelines for the management of adult lower respiratory tract infections
    • Woodhead M, Blasi F, Ewig S, et al. Guidelines for the management of adult lower respiratory tract infections. Clin Microbiol Infect 2011; 17 (Suppl 6): E1-E59.
    • (2011) Clin Microbiol Infect , vol.17 , Issue.SUPPL. 6
    • Woodhead, M.1    Blasi, F.2    Ewig, S.3
  • 3
    • 0035829842 scopus 로고    scopus 로고
    • Early goal-directed therapy in the treatment of severe sepsis and septic shock
    • Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001; 345:1368-1377.
    • (2001) N Engl J Med , vol.345 , pp. 1368-1377
    • Rivers, E.1    Nguyen, B.2    Havstad, S.3
  • 4
    • 30944463415 scopus 로고    scopus 로고
    • The duration of hypotension before the initiation of antibiotic treatment is a critical determinant of survival in a murine model of Escherichia coli septic shock: Association with serum lactate and inflammatory cytokine levels
    • DOI 10.1086/498909
    • Kumar A, Haery C, Paladugu B, et al. The duration of hypotension before the initiation of antibiotic treatment is a critical determinant of survival in a murine model of Escherichia coli septic shock: association with serum lactate and inflammatory cytokine levels. J Infect Dis 2006; 193:251-258. (Pubitemid 43113487)
    • (2006) Journal of Infectious Diseases , vol.193 , Issue.2 , pp. 251-258
    • Kumar, A.1    Haery, C.2    Paladugu, B.3    Kumar, A.4    Symeoneides, S.5    Taiberg, L.6    Osman, J.7    Trenholme, G.8    Opal, S.M.9    Goldfarb, R.10    Parrillo, J.E.11
  • 5
    • 80051951653 scopus 로고    scopus 로고
    • Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol
    • Puskarich MA, Trzeciak S, Shapiro NI, et al. Association between timing of antibiotic administration and mortality from septic shock in patients treated with a quantitative resuscitation protocol. Crit Care Med 2011; 39:2066-2071.
    • (2011) Crit Care Med , vol.39 , pp. 2066-2071
    • Puskarich, M.A.1    Trzeciak, S.2    Shapiro, N.I.3
  • 6
    • 0031035860 scopus 로고    scopus 로고
    • Dear SIRS, I'm sorry to say that i don't like you
    • Vincent JL. Dear SIRS, I'm sorry to say that I don't like you. Crit Care Med 1997; 25:372-374.
    • (1997) Crit Care Med , vol.25 , pp. 372-374
    • Vincent, J.L.1
  • 8
    • 2442642814 scopus 로고    scopus 로고
    • Determinants for hospitalization in 'low-risk' community acquired pneumonia
    • Aliyu ZY, Aliyu MH, McCormick K. Determinants for hospitalization in 'low-risk' community acquired pneumonia. BMC Infect Dis 2003; 3:11.
    • (2003) BMC Infect Dis , vol.3 , pp. 11
    • Aliyu, Z.Y.1    Aliyu, M.H.2    McCormick, K.3
  • 9
    • 77952578460 scopus 로고    scopus 로고
    • Proposed changes to management of lower respiratory tract infections in response to the Clostridium difficile epidemic
    • Chalmers JD, Al-Khairalla M, Short PM, et al. Proposed changes to management of lower respiratory tract infections in response to the Clostridium difficile epidemic. J Antimicrob Chemother 2010 ;65:608-618.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 608-618
    • Chalmers, J.D.1    Al-Khairalla, M.2    Short, P.M.3
  • 11
    • 77951245860 scopus 로고    scopus 로고
    • Which patients with lower respiratory tract infections need inpatient treatment? Perceptions of physicians, nurses, patients and relatives
    • Bahni C, Meier S, Spreiter P, et al. Which patients with lower respiratory tract infections need inpatient treatment? Perceptions of physicians, nurses, patients and relatives. BMC Pulm Med 2010; 10:12.
    • (2010) BMC Pulm Med , vol.10 , pp. 12
    • Bahni, C.1    Meier, S.2    Spreiter, P.3
  • 12
    • 70149088214 scopus 로고    scopus 로고
    • Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: The ProHOSP randomized controlled trial
    • Schuetz P, Christ-Crain M, Thomann R, et al. Effect of procalcitonin-based guidelines vs standard guidelines on antibiotic use in lower respiratory tract infections: the ProHOSP randomized controlled trial. JAMA 2009; 302:1059-1066.
    • (2009) JAMA , vol.302 , pp. 1059-1066
    • Schuetz, P.1    Christ-Crain, M.2    Thomann, R.3
  • 14
    • 44949176523 scopus 로고    scopus 로고
    • Risk prediction with procalcitonin and clinical rules in community-acquired pneumonia
    • e42
    • Huang DT, Weissfeld LA, Kellum JA, et al. Risk prediction with procalcitonin and clinical rules in community-acquired pneumonia. Ann Emerg Med 2008; 52:48-58; e42.
    • (2008) Ann Emerg Med , vol.52 , pp. 48-58
    • Huang, D.T.1    Weissfeld, L.A.2    Kellum, J.A.3
  • 16
    • 0033974755 scopus 로고    scopus 로고
    • A controlled trial of a critical pathway for treatment of community-acquired pneumonia. CAPITAL study investigators. Community-acquired pneumonia intervention trial assessing levofloxacin
    • Marrie TJ, Lau CY, Wheeler SL, et al. A controlled trial of a critical pathway for treatment of community-acquired pneumonia. CAPITAL study investigators. Community-acquired pneumonia intervention trial assessing levofloxacin. JAMA 2000; 283:749-755.
    • (2000) JAMA , vol.283 , pp. 749-755
    • Marrie, T.J.1    Lau, C.Y.2    Wheeler, S.L.3
  • 17
    • 38449105578 scopus 로고    scopus 로고
    • Biomarkers in respiratory tract infections: Diagnostic guides to antibiotic prescription, prognostic markers and mediators
    • DOI 10.1183/09031936.00166106
    • Christ-Crain M,Muller B. Biomarkers in respiratory tract infections: diagnostic guides to antibiotic prescription, prognostic markers and mediators. Eur Respir J 2007; 30:556-573. (Pubitemid 351182082)
    • (2007) European Respiratory Journal , vol.30 , Issue.3 , pp. 556-573
    • Christ-Crain, M.1    Muller, B.2
  • 18
    • 84863841392 scopus 로고    scopus 로고
    • Do sepsis biomarkers in the emergency room allow transition from bundled sepsis care to personalized patient care?
    • Schuetz P, Haubitz S, Mueller B. Do sepsis biomarkers in the emergency room allow transition from bundled sepsis care to personalized patient care? Curr Opin Crit Care 2012; 18:341-349.
    • (2012) Curr Opin Crit Care , vol.18 , pp. 341-349
    • Schuetz, P.1    Haubitz, S.2    Mueller, B.3
  • 20
    • 78651088658 scopus 로고    scopus 로고
    • Antimicrobial stewardship for inpatient facilities
    • Ohl CA, Luther VP. Antimicrobial stewardship for inpatient facilities. J Hosp Med 2011; 6 (Suppl 1):S4-S15.
    • (2011) J Hosp Med , vol.6 , Issue.SUPPL. 1
    • Ohl, C.A.1    Luther, V.P.2
  • 21
    • 63249115759 scopus 로고    scopus 로고
    • Antimicrobial stewardship in the intensive care unit: Advances and obstacles
    • Lawrence KL, Kollef MH. Antimicrobial stewardship in the intensive care unit: advances and obstacles. Am J Respir Crit Care Med 2009; 179:434-438.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 434-438
    • Lawrence, K.L.1    Kollef, M.H.2
  • 22
    • 67649090473 scopus 로고    scopus 로고
    • Procalcitonin and other biomarkers to improve assessment and antibiotic stewardship in infections:hope for hype?
    • Schuetz P, Christ-Crain M, Muller B. Procalcitonin and other biomarkers to improve assessment and antibiotic stewardship in infections:hope for hype? Swiss Med Wkly 2009; 139:318-326.
    • (2009) Swiss Med Wkly , vol.139 , pp. 318-326
    • Schuetz, P.1    Christ-Crain, M.2    Muller, B.3
  • 24
    • 77952273695 scopus 로고    scopus 로고
    • Procalcitonin levels predict bacteremia in patients with community-acquired pneumonia: A prospective cohort trial
    • Muller F, Christ-Crain M, Bregenzer T, et al. Procalcitonin levels predict bacteremia in patients with community-acquired pneumonia: a prospective cohort trial. Chest 2010; 138:121-129.
    • (2010) Chest , vol.138 , pp. 121-129
    • Muller, F.1    Christ-Crain, M.2    Bregenzer, T.3
  • 25
    • 1942441026 scopus 로고    scopus 로고
    • Procalcitonin and the calcitonin gene family of peptides in inflammation, infection, and sepsis: A journey from calcitonin back to its precursors
    • DOI 10.1210/jc.2002-021444
    • Becker KL. Procalcitonin and the calcitonin gene family of peptides in inflammation, infection, and sepsis: a journey from calcitonin back to its precursors. J Clin Endocrinol Metab 2004; 89:1512-1525. (Pubitemid 38507896)
    • (2004) Journal of Clinical Endocrinology and Metabolism , vol.89 , Issue.4 , pp. 1512-1525
    • Becker, K.L.1    Nylen, E.S.2    White, J.C.3    Muller, B.4    Snider Jr., R.H.5
  • 26
    • 18844427583 scopus 로고    scopus 로고
    • Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue
    • DOI 10.1210/en.2004-1424
    • Linscheid P, Seboek D, Zulewski H, et al. Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue. Endocrinology 2005; 146:2699-2708. (Pubitemid 40695573)
    • (2005) Endocrinology , vol.146 , Issue.6 , pp. 2699-2708
    • Linscheid, P.1    Seboek, D.2    Zulewski, H.3    Keller, U.4    Muller, B.5
  • 27
    • 3943108189 scopus 로고    scopus 로고
    • Expression and secretion of procalcitonin and calcitonin gene-related peptide by adherent monocytes and by macrophage-activated adipocytes
    • DOI 10.1097/01.CCM.0000134404.63292.71
    • Linscheid P, Seboek D, Schaer DJ, et al. Expression and secretion of procalcitonin and calcitonin gene-related peptide by adherent monocytes and by macrophage-activated adipocytes. Crit Care Med 2004; 32:1715-1721. (Pubitemid 39050523)
    • (2004) Critical Care Medicine , vol.32 , Issue.8 , pp. 1715-1721
    • Linscheid, P.1    Seboek, D.2    Schaer, D.J.3    Zulewski, H.4    Keller, U.5    Muller, B.6
  • 28
    • 80051637867 scopus 로고    scopus 로고
    • Procalcitonin algorithms for antibiotic therapy decisions: A systematic review of randomized controlled trials and recommendations for clinical algorithms
    • Schuetz P, Chiappa V, Briel M, Greenwald JL. Procalcitonin algorithms for antibiotic therapy decisions: a systematic review of randomized controlled trials and recommendations for clinical algorithms. Arch Intern Med 2011; 171:1322-1331.
    • (2011) Arch Intern Med , vol.171 , pp. 1322-1331
    • Schuetz, P.1    Chiappa, V.2    Briel, M.3    Greenwald, J.L.4
  • 29
    • 84873044315 scopus 로고    scopus 로고
    • Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections
    • Schuetz P, Muller B, Christ-Crain M, et al. Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections. Cochrane Database Syst Rev 2012; 9:CD007498.
    • (2012) Cochrane Database Syst Rev , vol.9
    • Schuetz, P.1    Muller, B.2    Christ-Crain, M.3
  • 30
    • 84864927322 scopus 로고    scopus 로고
    • Procalcitonin to guide initiation and duration of antibiotic treatment in acute respiratory infections: An individual patient data meta-analysis
    • Schuetz P, Briel M, Christ-Crain M, et al. Procalcitonin to guide initiation and duration of antibiotic treatment in acute respiratory infections: an individual patient data meta-analysis. Clin Infect Dis 2012; 55:651-662.
    • (2012) Clin Infect Dis , vol.55 , pp. 651-662
    • Schuetz, P.1    Briel, M.2    Christ-Crain, M.3
  • 31
    • 75949113583 scopus 로고    scopus 로고
    • Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): A multicentre randomised controlled trial
    • Bouadma L, Luyt CE, Tubach F, et al. Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial. Lancet 2010; 375:463-474.
    • (2010) Lancet , vol.375 , pp. 463-474
    • Bouadma, L.1    Luyt, C.E.2    Tubach, F.3
  • 33
    • 77952426755 scopus 로고    scopus 로고
    • Effectiveness of a procalcitonin algorithm to guide antibiotic therapy in respiratory tract infections outside of study conditions: A poststudy survey
    • Schuetz P, Batschwaroff M, Dusemund F, et al. Effectiveness of a procalcitonin algorithm to guide antibiotic therapy in respiratory tract infections outside of study conditions: a poststudy survey. Eur J Clin Microbiol Infect Dis 2010; 29:269-277.
    • (2010) Eur J Clin Microbiol Infect Dis , vol.29 , pp. 269-277
    • Schuetz, P.1    Batschwaroff, M.2    Dusemund, F.3
  • 34
    • 84861158484 scopus 로고    scopus 로고
    • Effectiveness and safety of procalcitonin-guided antibiotic therapy in lower respiratory tract infections in 'real life': An international, multicenter poststudy survey (ProREAL)
    • Albrich WC, Dusemund F, Bucher B, et al. Effectiveness and safety of procalcitonin-guided antibiotic therapy in lower respiratory tract infections in 'real life': an international, multicenter poststudy survey (ProREAL). Arch Intern Med 2012; 172:715-722.
    • (2012) Arch Intern Med , vol.172 , pp. 715-722
    • Albrich, W.C.1    Dusemund, F.2    Bucher, B.3
  • 37
    • 0035059902 scopus 로고    scopus 로고
    • Study of community acquired pneumonia aetiology (SCAPA) in adults admitted to hospital: Implications for management guidelines
    • DOI 10.1136/thorax.56.4.296
    • Lim WS, Macfarlane JT, Boswell TC, et al. Study of community acquired pneumonia aetiology (SCAPA) in adults admitted to hospital: implications for management guidelines. Thorax 2001; 56:296-301. (Pubitemid 32269810)
    • (2001) Thorax , vol.56 , Issue.4 , pp. 296-301
    • Lim, W.S.1    Macfarlane, J.T.2    Boswell, T.C.J.3    Harrison, T.G.4    Rose, D.5    Leinonen, M.6    Saikku, P.7
  • 38
    • 0038554228 scopus 로고    scopus 로고
    • Defining community acquired pneumonia severity on presentation to hospital: An international derivation and validation study
    • DOI 10.1136/thorax.58.5.377
    • Lim WS, van der Eerden MM, Laing R, et al. Defining community acquired pneumonia severity on presentation to hospital: an international derivation and validation study. Thorax 2003; 58:377-382. (Pubitemid 36560938)
    • (2003) Thorax , vol.58 , Issue.5 , pp. 377-382
    • Lim, W.S.1    Van Der Eerden, M.M.2    Laing, R.3    Boersma, W.G.4    Karalus, N.5    Town, G.I.6    Lewis, S.A.7    Macfarlane, J.T.8
  • 39
    • 33644877937 scopus 로고    scopus 로고
    • Pro-atrial natriuretic peptide is a prognostic marker in sepsis, similar to the APACHE II score: An observational study
    • Morgenthaler NG, Struck J, Christ-Crain M, et al. Pro-atrial natriuretic peptide is a prognostic marker in sepsis, similar to the APACHE II score: an observational study. Crit Care 2005; 9:R37-45.
    • (2005) Crit Care , vol.9
    • Morgenthaler, N.G.1    Struck, J.2    Christ-Crain, M.3
  • 40
    • 33646927080 scopus 로고    scopus 로고
    • Mid-regional pro-adrenomedullin as a prognostic marker in sepsis: An observational study
    • Christ-Crain M, Morgenthaler NG, Struck J, et al. Mid-regional pro-adrenomedullin as a prognostic marker in sepsis: an observational study. Crit Care 2005; 9:R816-824.
    • (2005) Crit Care , vol.9
    • Christ-Crain, M.1    Morgenthaler, N.G.2    Struck, J.3
  • 41
    • 34248330207 scopus 로고    scopus 로고
    • Pro-adrenomedullin to predict severity and outcome in community-acquired pneumonia (ISRCTN04176397)
    • Christ-Crain M, Morgenthaler NG, Stolz D, et al. Pro-adrenomedullin to predict severity and outcome in community-acquired pneumonia (ISRCTN04176397). Crit Care 2006; 10:R96.
    • (2006) Crit Care , vol.10
    • Christ-Crain, M.1    Morgenthaler, N.G.2    Stolz, D.3
  • 46
    • 34547668476 scopus 로고    scopus 로고
    • Copeptin, a stable peptide of the arginine vasopressin precursor, is elevated in hemorrhagic and septic shock
    • DOI 10.1097/SHK.0b013e318033e5da, PII 0002438220070800000015
    • Morgenthaler NG, Muller B, Struck J, et al. Copeptin, a stable peptide of the arginine vasopressin precursor, is elevated in hemorrhagic and septic shock. Shock 2007; 28:219-226. (Pubitemid 47220835)
    • (2007) Shock , vol.28 , Issue.2 , pp. 219-226
    • Morgenthaler, N.G.1    Muller, B.2    Struck, J.3    Bergmann, A.4    Redl, H.5    Christ-Crain, M.6
  • 48
    • 38449105578 scopus 로고    scopus 로고
    • Biomarkers in respiratory tract infections: Diagnostic guides to antibiotic prescription, prognostic markers and mediators
    • DOI 10.1183/09031936.00166106
    • Christ-Crain M, Muller B. Biomarkers in respiratory tract infections: diagnostic guides to antibiotic prescription, prognostic markers and mediators. Eur Respir J 2007; 30:556-573. (Pubitemid 351182082)
    • (2007) European Respiratory Journal , vol.30 , Issue.3 , pp. 556-573
    • Christ-Crain, M.1    Muller, B.2
  • 49
    • 34548463858 scopus 로고    scopus 로고
    • Biomarkers to improve diagnostic and prognostic accuracy in systemic infections
    • DOI 10.1097/MCC.0b013e3282c9ac2a, PII 0007519820071000000020
    • Schuetz P, Christ-Crain M, Muller B. Biomarkers to improve diagnostic and prognostic accuracy in systemic infections. Curr Opin Crit Care 2007; 13:578-585. (Pubitemid 47357461)
    • (2007) Current Opinion in Critical Care , vol.13 , Issue.5 , pp. 578-585
    • Schuetz, P.1    Christ-Crain, M.2    Muller, B.3
  • 50
    • 25444494129 scopus 로고    scopus 로고
    • Measurement of midregional proadrenomedullin in plasma with an immunoluminometric assay
    • DOI 10.1373/clinchem.2005.051110
    • Morgenthaler NG, Struck J, Alonso C, Bergmann A. Measurement of midregional proadrenomedullin in plasma with an immunoluminometric assay. Clin Chem 2005; 51:1823-1829. (Pubitemid 41368172)
    • (2005) Clinical Chemistry , vol.51 , Issue.10 , pp. 1823-1829
    • Morgenthaler, N.G.1    Struck, J.2    Alonso, C.3    Bergmann, A.4
  • 51
    • 0035685215 scopus 로고    scopus 로고
    • A review of the biological properties and clinical implications of adrenomedullin and proadrenomedullin N-terminal 20 peptide (PAMP), hypotensive and vasodilating peptides
    • DOI 10.1016/S0196-9781(01)00513-7, PII S0196978101005137
    • Eto T. A review of the biological properties and clinical implications of adrenomedullin and proadrenomedullin N-terminal 20 peptide (PAMP), hypotensive and vasodilating peptides. Peptides 2001; 22:1693-1711. (Pubitemid 34062786)
    • (2001) Peptides , vol.22 , Issue.11 , pp. 1693-1711
    • Eto, T.1
  • 52
    • 78649859320 scopus 로고    scopus 로고
    • Mid-regional proadrenomedullin as a novel predictor of mortality in patients with chronic heart failure
    • von Haehling S, Filippatos GS, Papassotiriou J, et al. Mid-regional proadrenomedullin as a novel predictor of mortality in patients with chronic heart failure. Eur J Heart Fail 2010; 12:484-491.
    • (2010) Eur J Heart Fail , vol.12 , pp. 484-491
    • Von Haehling, S.1    Filippatos, G.S.2    Papassotiriou, J.3
  • 53
    • 77953126410 scopus 로고    scopus 로고
    • Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections
    • Schuetz P, Wolbers M, Christ-Crain M, et al. Prohormones for prediction of adverse medical outcome in community-acquired pneumonia and lower respiratory tract infections. Crit Care 2010; 14:R106.
    • (2010) Crit Care , vol.14
    • Schuetz, P.1    Wolbers, M.2    Christ-Crain, M.3
  • 54
    • 77951646726 scopus 로고    scopus 로고
    • Mid-region pro-hormone markers for diagnosis and prognosis in acute dyspnea: Results from the BACH (Biomarkers in Acute Heart Failure) trial
    • Maisel A, Mueller C, Nowak R, et al. Mid-region pro-hormone markers for diagnosis and prognosis in acute dyspnea: results from the BACH (Biomarkers in Acute Heart Failure) trial. J Am Coll Cardiol 2010; 55:2062-2076.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 2062-2076
    • Maisel, A.1    Mueller, C.2    Nowak, R.3
  • 55
    • 67650505646 scopus 로고    scopus 로고
    • Plasma MR-proADM correlates to BMI and decreases in relation to leptin after gastric bypass surgery
    • (Silver Spring)
    • Vila G, Riedl M, Maier C, et al. Plasma MR-proADM correlates to BMI and decreases in relation to leptin after gastric bypass surgery. Obesity (Silver Spring) 2009; 17:1184-1188.
    • (2009) Obesity , vol.17 , pp. 1184-1188
    • Vila, G.1    Riedl, M.2    Maier, C.3
  • 56
    • 49449099368 scopus 로고    scopus 로고
    • Plasma pro-adrenomedullin but not plasma pro-endothelin predicts survival in exacerbations of COPD
    • Stolz D, Christ-Crain M, Morgenthaler NG, et al. Plasma pro-adrenomedullin but not plasma pro-endothelin predicts survival in exacerbations of COPD. Chest 2008; 134:263-272.
    • (2008) Chest , vol.134 , pp. 263-272
    • Stolz, D.1    Christ-Crain, M.2    Morgenthaler, N.G.3
  • 57
    • 33646927080 scopus 로고    scopus 로고
    • Mid-regional pro-adrenomedullin as a prognostic marker in sepsis: An observational study
    • Christ-Crain M, Morgenthaler NG, Struck J, et al. Mid-regional pro-adrenomedullin as a prognostic marker in sepsis: an observational study. Crit Care 2005; 9:R816-824.
    • (2005) Crit Care , vol.9
    • Christ-Crain, M.1    Morgenthaler, N.G.2    Struck, J.3
  • 58
    • 34248330207 scopus 로고    scopus 로고
    • Pro-adrenomedullin to predict severity and outcome in community-acquired pneumonia (ISRCTN04176397)
    • Christ-Crain M, Morgenthaler NG, Stolz D, et al. Pro-adrenomedullin to predict severity and outcome in community-acquired pneumonia (ISRCTN04176397). Crit Care 2006; 10:R96.
    • (2006) Crit Care , vol.10
    • Christ-Crain, M.1    Morgenthaler, N.G.2    Stolz, D.3
  • 59
    • 78649882826 scopus 로고    scopus 로고
    • Cardiovascular and inflammatory biomarkers to predict short- and long-term survival in community-acquired pneumonia: Results from the German Competence Network, CAPNETZ
    • Krüger S, Ewig S, Giersdorf S, et al. Cardiovascular and inflammatory biomarkers to predict short- and long-term survival in community-acquired pneumonia: results from the German Competence Network, CAPNETZ. Am J Respir Crit Care Med 2010; 182:1426-1434.
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 1426-1434
    • Krüger, S.1    Ewig, S.2    Giersdorf, S.3
  • 60
    • 79955517658 scopus 로고    scopus 로고
    • Enhancement of CURB65 score with proadrenomedullin (CURB65-A) for outcome prediction in lower respiratory tract infections: Derivation of a clinical algorithm
    • Albrich WC, Dusemund F, Ruegger K, et al. Enhancement of CURB65 score with proadrenomedullin (CURB65-A) for outcome prediction in lower respiratory tract infections: derivation of a clinical algorithm. BMC Infect Dis 2011; 11:112.
    • (2011) BMC Infect Dis , vol.11 , pp. 112
    • Albrich, W.C.1    Dusemund, F.2    Ruegger, K.3
  • 61
    • 79958003426 scopus 로고    scopus 로고
    • Inflammatory responses predict longterm mortality risk in community-acquired pneumonia
    • Guertler C, Wirz B, Christ-Crain M, et al. Inflammatory responses predict longterm mortality risk in community-acquired pneumonia. Eur Respir J 2011; 37:1439-1446.
    • (2011) Eur Respir J , vol.37 , pp. 1439-1446
    • Guertler, C.1    Wirz, B.2    Christ-Crain, M.3
  • 62
    • 70049112524 scopus 로고    scopus 로고
    • Midregional proadrenomedullin as a prognostic tool in community-acquired pneumonia
    • Huang DT, Angus DC, Kellum JA, et al. Midregional proadrenomedullin as a prognostic tool in community-acquired pneumonia. Chest 2009; 136:823-831.
    • (2009) Chest , vol.136 , pp. 823-831
    • Huang, D.T.1    Angus, D.C.2    Kellum, J.A.3
  • 63
    • 84870937155 scopus 로고    scopus 로고
    • Proadrenomedullin, a useful tool for risk stratification in high Pneumonia Severity Index score community acquired pneumonia
    • Courtais C, Kuster N, Dupuy AM, et al. Proadrenomedullin, a useful tool for risk stratification in high Pneumonia Severity Index score community acquired pneumonia. Am J Emerg Med 2013, 31:215-221.
    • (2013) Am J Emerg Med , vol.31 , pp. 215-221
    • Courtais, C.1    Kuster, N.2    Dupuy, A.M.3
  • 64
    • 84859207085 scopus 로고    scopus 로고
    • Prognostic power of proadrenomedullin in community-acquired pneumonia is independent of aetiology
    • Bello S, Lasierra AB, Minchole E, et al. Prognostic power of proadrenomedullin in community-acquired pneumonia is independent of aetiology. Eur Respir J 2012; 39:1144-1155.
    • (2012) Eur Respir J , vol.39 , pp. 1144-1155
    • Bello, S.1    Lasierra, A.B.2    Minchole, E.3
  • 65
    • 84870618653 scopus 로고    scopus 로고
    • Proadrenomedullin improves REAICU score for predicting early severe community-acquired pneumonia
    • [Epub ahead of print]
    • Renaud B, Schuetz P, Claessens YE, et al. Proadrenomedullin improves REAICU score for predicting early severe community-acquired pneumonia. Chest 2012. [Epub ahead of print]
    • (2012) Chest
    • Renaud, B.1    Schuetz, P.2    Claessens, Y.E.3
  • 66
    • 84859501976 scopus 로고    scopus 로고
    • Prognostic value of proadrenomedullin in severe sepsis and septic shock patients with community-acquired pneumonia
    • Suberviola B, Castellanos-Ortega A, Llorca J, et al. Prognostic value of proadrenomedullin in severe sepsis and septic shock patients with community-acquired pneumonia. Swiss Med Wkly 2012; 142: w13542.
    • (2012) Swiss Med Wkly , vol.142
    • Suberviola, B.1    Castellanos-Ortega, A.2    Llorca, J.3
  • 67
    • 77957836356 scopus 로고    scopus 로고
    • The impact of a delay in intensive care unit admission for community-acquired pneumonia
    • Phua J, Ngerng WJ, Lim TK. The impact of a delay in intensive care unit admission for community-acquired pneumonia. Eur Respir J 2010; 36:826-833.
    • (2010) Eur Respir J , vol.36 , pp. 826-833
    • Phua, J.1    Ngerng, W.J.2    Lim, T.K.3
  • 68
    • 73449089736 scopus 로고    scopus 로고
    • Association between timing of intensive care unit admission and outcomes for emergency department patients with community-acquired pneumonia
    • Renaud B, Santin A, Coma E, et al. Association between timing of intensive care unit admission and outcomes for emergency department patients with community-acquired pneumonia. Crit Care Med 2009; 37:2867-2874.
    • (2009) Crit Care Med , vol.37 , pp. 2867-2874
    • Renaud, B.1    Santin, A.2    Coma, E.3
  • 69
    • 80052232993 scopus 로고    scopus 로고
    • Optimised patient transfer using an innovative multidisciplinary assessment in Kanton Aargau (OPTIMA I): An observational survey in lower respiratory tract infections
    • Albrich WC, Ruegger K, Dusemund F, et al. Optimised patient transfer using an innovative multidisciplinary assessment in Kanton Aargau (OPTIMA I): an observational survey in lower respiratory tract infections. Swiss Med Wkly 2011; 141:w13237.
    • (2011) Swiss Med Wkly , vol.141
    • Albrich, W.C.1    Ruegger, K.2    Dusemund, F.3


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