The duration of hypotension before the initiation of antibiotic treatment is a critical determinant of survival in a murine model of Escherichia coli septic shock: Association with serum lactate and inflammatory cytokine levels

Journal of Infectious Diseases

Volumn 193, Issue 2, 2006, Pages 251-258

  Kumar, Anand ^a,c,f   Haery, Cameron ^b   Paladugu, Bhanu ^a   Kumar, Aseem ^d   Symeoneides, Simon ^b   Taiberg, Leo ^b   Osman, Jailan ^b   Trenholme, Gordon ^b   Opal, Steven M ^e   Goldfarb, Roy ^a   Parrillo, Joseph E ^a  

^a RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^b RUSH UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF MANITOBA   (Canada)

^d LAURENTIAN UNIVERSITY   (Canada)

^e BROWN UNIVERSITY   (United States)

^f HEALTH SCIENCES CENTRE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; ANTIBIOTIC AGENT; CYTOKINE; GELATIN; INTERLEUKIN 6; LACTIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBIOTIC THERAPY; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; ESCHERICHIA COLI; HEART OUTPUT; HEART RATE; HEART STROKE VOLUME; HEMODYNAMICS; HYPOTENSION; INFLAMMATION; LACTATE BLOOD LEVEL; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SEPTIC SHOCK; STRESS; SURVIVAL RATE;

ANIMALS; ANTI-BACTERIAL AGENTS; CARDIAC OUTPUT; DISEASE MODELS, ANIMAL; ESCHERICHIA COLI INFECTIONS; HEART RATE; HYPOTENSION; INTERLEUKIN-6; LACTIC ACID; MALE; MICE; SHOCK, SEPTIC; STATISTICS; STROKE VOLUME; SURVIVAL ANALYSIS; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 30944463415     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/498909     Document Type: Article

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