Spherical agglomerates of pure drug nanoparticles for improved pulmonary delivery in dry powder inhalers

Journal of Nanoparticle Research

Volumn 15, Issue 4, 2013, Pages

  Hu, Jun ^a,b   Dong, Yuancai ^a   Pastorin, Giorgia ^b   Ng, Wai Kiong ^a,b   Tan, Reginald B H ^a,b  

^a INSTITUTE OF CHEMICAL AND ENGINEERING SCIENCES   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Dry powder inhalers; Keywords:: Spherical agglomerates; Liquid antisolvent precipitation; Pure drug nanoparticles; Sodium cromoglicate; Spray drying

Indexed keywords

AEROSOLS; AGGLOMERATION; ATOMIZERS; CONTROLLED DRUG DELIVERY; DEPOSITION; DRUG PRODUCTS; FIELD EMISSION MICROSCOPES; LIQUIDS; NANOPARTICLES; PARTICLE SIZE ANALYSIS; RESPIRATORY MECHANICS; SCANNING ELECTRON MICROSCOPY; SPHERES; SPRAY DRYING;

DRUG NANO PARTICLES; DRY POWDER INHALER; LIQUID ANTISOLVENT; SODIUM CROMOGLICATE; SPHERICAL AGGLOMERATES;

PRECIPITATION (CHEMICAL);

CROMOGLYCATE DISODIUM; NANOPARTICLE;

AEROSOL; AQUEOUS SOLUTION; ARTICLE; CONTROLLED STUDY; DENSITY; DRUG DELIVERY SYSTEM; DRUG SOLUTION; FIELD EMISSION SCANNING ELECTRON MICROSCOPY; GEOMETRY; IN VITRO STUDY; LASER DIFFRACTION; PARTICLE SIZE; PHYSICAL CHEMISTRY; POWDER INHALER; PRIORITY JOURNAL; SPRAY DRYING; X RAY DIFFRACTION;

EID: 84874931115     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-013-1560-2     Document Type: Article

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