The role of diallyl sulfides and dipropyl sulfides in the in vitro antimicrobial activity of the essential oil of garlic, Allium sativum L., and leek, Allium porrum L.

Phytotherapy Research

Volumn 27, Issue 3, 2013, Pages 380-383

  Casella, Sergio ^a   Leonardi, Michele ^a   Melai, Bernardo ^a   Fratini, Filippo ^a   Pistelli, Luisa ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

antibacterial activity; diallyl sulfides; dipropyl sulfides; Escherichia coli; garlic; gas chromatography mass spectrometry; leek; Pseudomonas aeruginosa; Staphylococcus aureus

Indexed keywords

ALLIUM PORRUM ESSENTIAL OIL; ALLIUM SATIVUM ESSENTIAL OIL; ALLYL SULFIDE; ANTIINFECTIVE AGENT; CIPROFLOXACIN; DIALLYL DISULFIDE; DIALLYL MONOSULFIDE; DIALLYL TETRASULFIDE; DIALLYL TRISULFIDE; DIPROPYL DISULFIDE; DIPROPYL SULFIDE; DIPROPYL TETRASULFIDE; DIPROPYL TRISULFIDE; ESSENTIAL OIL; GENTAMICIN; METHYLPROPYL MONOSULFIDE; SULFIDE; TETRACYCLINE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; CONTROLLED STUDY; DISK DIFFUSION; DRUG IDENTIFICATION; ESCHERICHIA COLI; GARLIC; GROWTH INHIBITION; IN VITRO STUDY; LEEK; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHYTOCHEMISTRY; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

ALLIUM; ALLYL COMPOUNDS; ANTI-BACTERIAL AGENTS; DISULFIDES; ESCHERICHIA COLI; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; OILS, VOLATILE; PLANT OILS; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; SULFIDES;

ALLIACEAE; ALLIUM; ALLIUM PORRUM; ALLIUM SATIVUM; ESCHERICHIA COLI; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS;

EID: 84874930391     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.4725     Document Type: Article

References (22)

1. Adams RP,. 1995. Identification of essential oil components by gas chromatography-mass spectroscopy. Allured, Carol Stream: Illinois.
2. Agarwal KC,. 1996. Therapeutic actions of garlic constituents. Med Res Rev 16: 111-124. (Pubitemid 26037077)
3. Arora SD, Kaur J,. 1999. Antimicrobical activity of spices. J Antimicrob Agents 12: 257-262.
4. Cavallito CJ, Bailey JH,. 1944. Allicin, the antibacterial principle of Allium sativum. Isolation, physical proprieties and antibacterial action. J Am Chem Soc 66: 1950-1951.
5. Davies NW,. 1990. Gas Chromatographic retention indices of monoterpenes and sesquiterpenes on methyl silicone and Carbowax 20M phases. J. Chromatogr 503: 1-24. (Pubitemid 20086004)
6. Delaha EC, Garagusi VF,. 1985. Inhibition of mycobacteria by garlic extract (Allium sativum). Antimicrob Agents Chemother 27: 485-486. (Pubitemid 15097643)
7. De Witt JC, Notermans S, Gorin N, Kampelmacher EH,. 1979. Effect of garlic oil or onion oil on toxin production by Chlostridium botulinum in meat slurry. J Food Protect 42: 222-224.
8. Gonzalez-Fandos E, Garcia-Lopez ML, Sierra ML, Otero A,. 1994. Staphylococcal growth and enterotoxins (A-D) and thermonuclease synthesis in the presence of dehydrated garlic. J Appl Bacteriol 77: 549-552. (Pubitemid 24339329)
9. Jennings W, Shibamoto T,. 1980. Qualitative Analysis of Flavor and Fragrance Volatiles by Glass capillary Gas Chromatography. Academic Press: New York.
10. Jezova L, Rafinski T, Wrocinski T,. 1966. Investigations on the antibiotic activity of Allium sativum L. Herba Pol 12: 3-13.
11. Johnson MG, Vaoughn RH,. 1960. Death of Salmonella typhimurium and Escherichia coli in the presence of freshly reconstituted dehydrate garlic and onion. Appl Microbiol 17: 903-905.
12. Lawson LD, Wang ZJ, Hughes BG,. 1991. Identification and HPLC quantification of the sulphides and dialk(en)yl thiosulfinates in commercial garlic products. Planta Med 57: 363-370.
13. Liu CT, Chen H-W, Sheen LY, Kung Y-L, Chen P C-H, Lii C-K,. 1998. Analytical methods-effect of garlic oil on hepatic arachidonic acid content and immune response in rats. J Agric Food Chem 46: 4642-4647. (Pubitemid 128489980)
14. Massada Y,. 1976. Analysis of Essential Oils by Gas Chromatography and Mass Spectrometry. John Wiley & Sons: New York.
15. National Committee for Clinical Laboratory Standard (NCCLS). 2002. Performance Standards for Antimicrobial Susceptibility Testing, Tweltfh Internatonal Supplement. NCCLS: Wayne, PA, M100-S12.
16. O'Gara EA, Hill DJ, Maslin DJ,. 2000. Activities of garlic oil, garlic powder and their diallyl constituents against Helicobacter pylori. Appl Envir Microbiol 66: 2269-2273. (Pubitemid 30253767)
17. Rose P, Whiteman M, Moore PK, Zhu ZY,. 2005. Bioactive S-alk(en)yl cysteine sulfoxide metabolites in the genus Allium: the chemistry of potential therapeutic agents. Nat Prod Rep 22: 351-368. (Pubitemid 40885716)
18. Shyh-Ming T, Mei-Chin Y,. 2001. In-vitro antimicrobial activity of four diallyl sulphides occurring naturally in garlic and Chinese leek oils. J Med Microbiol 50: 646-649.
19. Stenhagen E, Abrahamsson S, McLafferty FW,. 1974. Registry of Mass Spectral Data. John Wiley & Sons: New York.
20. Swigar AA, Silverstein RM,. 1981. Monoterpenes. Aldrich Chem. Comp.: Milwaukee.
21. Wargovich MJ,. 1987. Diallyl sulphide, a flavor component of garlic (Allium sativum) inhibits dimethylhydrazyne-induced colon cancer. Carcinogenesis 8: 487-489. (Pubitemid 17126191)
22. Yoshida S, Katsuzaki H, Othas R, Yoshida H, Okta R, Ishikawa K, Fukuda H,. 1999. An organosolfur compound isolated from oil-macerated garlic extract, and its antimicrobial effect. Biosci Biotechnol Biochem 63: 588-590. (Pubitemid 129555513)