-
2
-
-
84865408903
-
Role of angiogenesis in the pathogenesis of cancer
-
22677191 10.1016/j.ctrv.2012.04.006 1:CAS:528:DC%2BC38XosVKitL0%3D
-
Hoff PM, Machado KK (2012) Role of angiogenesis in the pathogenesis of cancer. Cancer Treat Rev 38:825-833
-
(2012)
Cancer Treat Rev
, vol.38
, pp. 825-833
-
-
Hoff, P.M.1
Machado, K.K.2
-
3
-
-
0032944435
-
Expression of vascular endothelial growth factor mRNA in non-small-cell lung carcinomas
-
9888482 10.1038/sj.bjc.6690058 1:CAS:528:DyaK1MXmvFensA%3D%3D
-
Fontanini G, Boldrini L, Chine S, Pisaturo F, Basolo F et al (1999) Expression of vascular endothelial growth factor mRNA in non-small-cell lung carcinomas. Br J Cancer 79:363-369
-
(1999)
Br J Cancer
, vol.79
, pp. 363-369
-
-
Fontanini, G.1
Boldrini, L.2
Chine, S.3
Pisaturo, F.4
Basolo, F.5
-
4
-
-
1642555978
-
Expression of vascular endothelial growth factor (VEGF) and association with microvessel density in small-cell and non-small-cell lung carcinomas
-
14702169 1:CAS:528:DC%2BD2cXjtFyrt7s%3D
-
Stefanou D, Batistatou A, Arkoumani E, Ntzani E, Agnantis NJ (2004) Expression of vascular endothelial growth factor (VEGF) and association with microvessel density in small-cell and non-small-cell lung carcinomas. Histol Histopathol 19:37-42
-
(2004)
Histol Histopathol
, vol.19
, pp. 37-42
-
-
Stefanou, D.1
Batistatou, A.2
Arkoumani, E.3
Ntzani, E.4
Agnantis, N.J.5
-
5
-
-
0034024352
-
Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancer
-
10780522 10.1054/bjoc.1999.1129
-
O'Byrne KJ, Koukourakis MI, Giatromanolaki A, Cox G, Turley H et al (2000) Vascular endothelial growth factor, platelet-derived endothelial cell growth factor and angiogenesis in non-small-cell lung cancer. Br J Cancer 82:1427-1432
-
(2000)
Br J Cancer
, vol.82
, pp. 1427-1432
-
-
O'Byrne, K.J.1
Koukourakis, M.I.2
Giatromanolaki, A.3
Cox, G.4
Turley, H.5
-
6
-
-
0035155064
-
Vascular endothelial growth factor expression in stage i non-small cell lung cancer correlates with neoangiogenesis and a poor prognosis
-
11206229 10.1007/s10434-001-0072-y 1:STN:280:DC%2BD3M7lsFektg%3D%3D
-
Han H, Silverman JF, Santucci TS, Macherey RS, d'Amato TA et al (2001) Vascular endothelial growth factor expression in stage I non-small cell lung cancer correlates with neoangiogenesis and a poor prognosis. Ann Surg Oncol 8:72-79
-
(2001)
Ann Surg Oncol
, vol.8
, pp. 72-79
-
-
Han, H.1
Silverman, J.F.2
Santucci, T.S.3
Macherey, R.S.4
D'Amato, T.A.5
-
7
-
-
0035863288
-
Vascular endothelial growth factor 189 mRNA isoform expression specifically correlates with tumor angiogenesis, patient survival, and postoperative relapse in non-small-cell lung cancer
-
11208836 1:CAS:528:DC%2BD3MXhtVekt7Y%3D
-
Yuan A, Yu CJ, Kuo SH, Chen WJ, Lin FY et al (2001) Vascular endothelial growth factor 189 mRNA isoform expression specifically correlates with tumor angiogenesis, patient survival, and postoperative relapse in non-small-cell lung cancer. J Clin Oncol 19:432-441
-
(2001)
J Clin Oncol
, vol.19
, pp. 432-441
-
-
Yuan, A.1
Yu, C.J.2
Kuo, S.H.3
Chen, W.J.4
Lin, F.Y.5
-
8
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
7683111 10.1038/362841a0 1:CAS:528:DyaK3sXktVKju7s%3D
-
Kim KJ, Li B, Winer J, Armanini M, Gillett N et al (1993) Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 362:841-844
-
(1993)
Nature
, vol.362
, pp. 841-844
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
Armanini, M.4
Gillett, N.5
-
9
-
-
0031766832
-
Antitumor effect of a neutralizing antibody to vascular endothelial growth factor on liver metastasis of endocrine neoplasm
-
9818029 10.1111/j.1349-7006.1998.tb00651.x 1:CAS:528:DyaK1cXmsVyrtLo%3D
-
Konno H, Arai T, Tanaka T, Baba M, Matsumoto K et al (1998) Antitumor effect of a neutralizing antibody to vascular endothelial growth factor on liver metastasis of endocrine neoplasm. Jpn J Cancer Res 89:933-939
-
(1998)
Jpn J Cancer Res
, vol.89
, pp. 933-939
-
-
Konno, H.1
Arai, T.2
Tanaka, T.3
Baba, M.4
Matsumoto, K.5
-
10
-
-
33750373924
-
Mechanisms of action of bevacizumab as a component of therapy for metastatic colorectal cancer
-
17145519 10.1053/j.seminoncol.2006.08.002 1:CAS:528:DC%2BD28Xhtlajt7rK
-
Ellis LM (2006) Mechanisms of action of bevacizumab as a component of therapy for metastatic colorectal cancer. Semin Oncol 33:S1-7
-
(2006)
Semin Oncol
, vol.33
, pp. 1-7
-
-
Ellis, L.M.1
-
11
-
-
84874938684
-
Tumour biomarker and plasma time course data from Abigail, a phase II study of 1st-line bevacizumab + chemotherapy in advanced non-squamous non-small-cell lung cancer (ns-NSCLC)
-
Abstract 1236PD
-
Reck MG, VA; Juhasz, E;Szima, B; Orlov, S; Yu, C; Pallaud, C; Scherer, SJ; Archer, V; Mok, TSK (2012) Tumour biomarker and plasma time course data from Abigail, a phase II study of 1st-line bevacizumab + chemotherapy in advanced non-squamous non-small-cell lung cancer (ns-NSCLC). Ann Oncol 37th ESMO Conference: Abstract 1236PD.
-
(2012)
Ann Oncol 37th ESMO Conference
-
-
Reck, M.G.1
Juhasz, V.A.2
Szima, E.3
Orlov, B.4
Yu, S.5
Pallaud, C.6
Scherer, C.7
Archer, S.J.8
Mok, V.9
-
12
-
-
2942657615
-
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
-
15169807 10.1200/JCO.2004.11.022 1:CAS:528:DC%2BD2cXpsVWltrg%3D
-
Johnson DH, Fehrenbacher L, Novotny WF, Herbst RS, Nemunaitis JJ et al (2004) Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol 22:2184-2191
-
(2004)
J Clin Oncol
, vol.22
, pp. 2184-2191
-
-
Johnson, D.H.1
Fehrenbacher, L.2
Novotny, W.F.3
Herbst, R.S.4
Nemunaitis, J.J.5
-
13
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
17167137 10.1056/NEJMoa061884 1:CAS:528:DC%2BD28XhtlWqsbzI
-
Sandler A, Gray R, Perry MC, Brahmer J, Schiller JH et al (2006) Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 355:2542-2550
-
(2006)
N Engl J Med
, vol.355
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
Brahmer, J.4
Schiller, J.H.5
-
14
-
-
62449124416
-
Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil
-
19188680 10.1200/JCO.2007.14.5466 1:CAS:528:DC%2BD1MXktFKhsL0%3D
-
Reck M, von Pawel J, Zatloukal P, Ramlau R, Gorbounova V et al (2009) Phase III trial of cisplatin plus gemcitabine with either placebo or bevacizumab as first-line therapy for nonsquamous non-small-cell lung cancer: AVAil. J Clin Oncol 27:1227-1234
-
(2009)
J Clin Oncol
, vol.27
, pp. 1227-1234
-
-
Reck, M.1
Von Pawel, J.2
Zatloukal, P.3
Ramlau, R.4
Gorbounova, V.5
-
15
-
-
77951473661
-
Overall survival with cisplatin-gemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: Results from a randomised phase III trial (AVAiL)
-
20150572 10.1093/annonc/mdq020 1:STN:280:DC%2BC3cjmtleltw%3D%3D
-
Reck M, von Pawel J, Zatloukal P, Ramlau R, Gorbounova V et al (2010) Overall survival with cisplatin-gemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: results from a randomised phase III trial (AVAiL). Ann Oncol 21:1804-1809
-
(2010)
Ann Oncol
, vol.21
, pp. 1804-1809
-
-
Reck, M.1
Von Pawel, J.2
Zatloukal, P.3
Ramlau, R.4
Gorbounova, V.5
-
16
-
-
77956266591
-
Treatment outcomes by tumor histology in Eastern Cooperative Group Study E4599 of bevacizumab with paclitaxel/carboplatin for advanced non-small cell lung cancer
-
20686429 10.1097/JTO.0b013e3181da36f4
-
Sandler A, Yi J, Dahlberg S, Kolb MM, Wang L et al (2010) Treatment outcomes by tumor histology in Eastern Cooperative Group Study E4599 of bevacizumab with paclitaxel/carboplatin for advanced non-small cell lung cancer. J Thorac Oncol 5:1416-1423
-
(2010)
J Thorac Oncol
, vol.5
, pp. 1416-1423
-
-
Sandler, A.1
Yi, J.2
Dahlberg, S.3
Kolb, M.M.4
Wang, L.5
-
17
-
-
84861973944
-
Innovations: Randomized phase II trial of erlotinib (E)/bevacizumab (B) compared with cisplatin (P)/gemcitabine (G) plus B in first-line treatment of advanced nonsquamous (NS) non-small cell lung cancer (NSCLC)
-
Thomas MR, A; Fischer, J.R.; Andreas, S; Kortsik, C; Grah, C; Serke, MH; von Eiff, M; Witt, C; Kollmeier, J; Müller, E; Müller, L; Schenk, M; Heine, R; Behringer, DM; Schroeder, M; Reinmuth, N; Schnabel, P; Acker, T; Wolf, TM (2011) Innovations: Randomized phase II trial of erlotinib (E)/bevacizumab (B) compared with cisplatin (P)/gemcitabine (G) plus B in first-line treatment of advanced nonsquamous (NS) non-small cell lung cancer (NSCLC). J Clin Oncol 29, suppl.
-
(2011)
J Clin Oncol
, vol.29
, Issue.SUPPL.
-
-
Thomas, M.1
Fischer, J.R.2
Andreas, S.3
Kortsik, C.4
Grah, C.5
Serke, M.H.6
Von Eiff, M.7
Witt, C.8
Kollmeier, J.9
Müller, E.10
Müller, L.11
Schenk, M.12
Heine, R.13
Behringer, D.M.14
Schroeder, M.15
Reinmuth, N.16
Schnabel, P.17
Acker, T.18
Wolf, T.M.19
-
18
-
-
77955268612
-
Safety and efficacy of first-line bevacizumab-based therapy in advanced non-squamous non-small-cell lung cancer (SAiL, MO19390): A phase 4 study
-
20650686 10.1016/S1470-2045(10)70151-0 1:CAS:528:DC%2BC3cXps1Wks7s%3D
-
Crino L, Dansin E, Garrido P, Griesinger F, Laskin J et al (2010) Safety and efficacy of first-line bevacizumab-based therapy in advanced non-squamous non-small-cell lung cancer (SAiL, MO19390): a phase 4 study. Lancet Oncol 11:733-740
-
(2010)
Lancet Oncol
, vol.11
, pp. 733-740
-
-
Crino, L.1
Dansin, E.2
Garrido, P.3
Griesinger, F.4
Laskin, J.5
-
19
-
-
84866597083
-
Metastatic non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
-
10.1093/annonc/mds226
-
Peters SA AA, Gridelli C, Reck M, Kerr K, Felip E (2012) Metastatic non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 23(supplement 7):vii56-vii64
-
(2012)
Ann Oncol
, vol.23
, Issue.SUPPL. 7
-
-
Peters Sa, A.A.1
Gridelli, C.2
Reck, M.3
Kerr, K.4
Felip, E.5
-
20
-
-
84867900893
-
Bevacizumab maintenance in patients with advanced non-small-cell lung cancer, clinical patterns, and outcomes in the eastern cooperative oncology group 4599 study: Results of an exploratory analysis
-
23059774 10.1097/JTO.0b013e318265b500 1:CAS:528:DC%2BC38XhsFSgt73K
-
Lopez-Chavez A, Young T, Fages S, Leon L, Schiller JH et al (2012) Bevacizumab maintenance in patients with advanced non-small-cell lung cancer, clinical patterns, and outcomes in the eastern cooperative oncology group 4599 study: results of an exploratory analysis. J Thorac Oncol 7:1707-1712
-
(2012)
J Thorac Oncol
, vol.7
, pp. 1707-1712
-
-
Lopez-Chavez, A.1
Young, T.2
Fages, S.3
Leon, L.4
Schiller, J.H.5
-
21
-
-
84860507572
-
MO19390 (SAiL): Bleeding events in a phase IV study of first-line bevacizumab with chemotherapy in patients with advanced non-squamous NSCLC
-
22236866 10.1016/j.lungcan.2011.11.020
-
Dansin E, Cinieri S, Garrido P, Griesinger F, Isla D et al (2012) MO19390 (SAiL): bleeding events in a phase IV study of first-line bevacizumab with chemotherapy in patients with advanced non-squamous NSCLC. Lung Cancer 76:373-379
-
(2012)
Lung Cancer
, vol.76
, pp. 373-379
-
-
Dansin, E.1
Cinieri, S.2
Garrido, P.3
Griesinger, F.4
Isla, D.5
-
22
-
-
84874943048
-
Cumulative exposure to bevacizumab (BV) after disease progression (PD) correlates with survival in non-small cell lung cancer (NSCLC): A time-dependent analysis of the ARIES observational cohort study
-
Lynch TJ, M; Spigel, DR; Wozniak, A; Leon, L; Fish, S; Flick, ED; Dalal, D; Kosty, MP (2012) Cumulative exposure to bevacizumab (BV) after disease progression (PD) correlates with survival in non-small cell lung cancer (NSCLC): a time-dependent analysis of the ARIES observational cohort study. Ann Oncol 37th ESMO Conference.
-
(2012)
Ann Oncol 37th ESMO Conference
-
-
Lynch, T.J.1
Spigel, M.2
Wozniak, D.R.3
Leon, A.4
Fish, L.5
Flick, S.6
Dalal, E.D.7
Kosty, D.8
-
23
-
-
79955565439
-
Bevacizumab treatment to progression after chemotherapy: Outcomes from a U.S. community practice network
-
21441299 10.1634/theoncologist.2010-0287 1:CAS:528:DC%2BC3MXhtlSktrvI
-
Nadler E, Yu E, Ravelo A, Sing A, Forsyth M et al (2011) Bevacizumab treatment to progression after chemotherapy: outcomes from a U.S. community practice network. Oncologist 16:486-496
-
(2011)
Oncologist
, vol.16
, pp. 486-496
-
-
Nadler, E.1
Yu, E.2
Ravelo, A.3
Sing, A.4
Forsyth, M.5
-
24
-
-
84874933416
-
AVAPERL (MO22089): Final efficacy outcomes for patients with advanced nonsquamous non-small cell lung cancer randomized to continuation maintenance with bevacizumab or bevacizumab + pemetrexed after first-line bevacizumab-cisplatin + pemetrexed treatment
-
Barlesi FdC, J; Dvornichenko, V; Kim, JH; Pazzola, A; Rittmeyer, A; Vikström, A; Mitchell, L; Wong, EK; Gorbunova, V (2011) AVAPERL (MO22089): Final efficacy outcomes for patients with advanced nonsquamous non-small cell lung cancer randomized to continuation maintenance with bevacizumab or bevacizumab + pemetrexed after first-line bevacizumab-cisplatin + pemetrexed treatment. ELCC 2011.
-
(2011)
ELCC 2011
-
-
Barlesi Fdc, J.1
-
25
-
-
84874940403
-
AVAPERL (MO22089): Final safety of maintenance bevacizmab +/- pemetrexed in patients with advanced non-squamous non-small cell lung cancer after first-line bevacizumab-cisplatin-pemetrexed treatment
-
Ahn MG, R; Mezger, J (2011) AVAPERL (MO22089): Final safety of maintenance bevacizmab +/- pemetrexed in patients with advanced non-squamous non-small cell lung cancer after first-line bevacizumab-cisplatin-pemetrexed treatment. EMCC 201.
-
(2011)
EMCC 201
-
-
Ahn, M.G.1
Mezger, R.2
-
26
-
-
84857507055
-
Maintenance therapy with pemetrexed plus best supportive care versus placebo plus best supportive care after induction therapy with pemetrexed plus cisplatin for advanced non-squamous non-small-cell lung cancer (PARAMOUNT): A double-blind, phase 3, randomised controlled trial
-
22341744 10.1016/S1470-2045(12)70063-3 1:CAS:528:DC%2BC38XjsVCgsbY%3D
-
Paz-Ares L, de Marinis F, Dediu M, Thomas M, Pujol JL et al (2012) Maintenance therapy with pemetrexed plus best supportive care versus placebo plus best supportive care after induction therapy with pemetrexed plus cisplatin for advanced non-squamous non-small-cell lung cancer (PARAMOUNT): a double-blind, phase 3, randomised controlled trial. Lancet Oncol 13:247-255
-
(2012)
Lancet Oncol
, vol.13
, pp. 247-255
-
-
Paz-Ares, L.1
De Marinis, F.2
Dediu, M.3
Thomas, M.4
Pujol, J.L.5
-
27
-
-
78650515286
-
Efficacy and safety of bevacizumab-based therapy in elderly patients with advanced or recurrent nonsquamous non-small cell lung cancer in the phase III BO17704 study (AVAiL)
-
20978447 10.1097/JTO.0b013e3181f49c22
-
Leighl NB, Zatloukal P, Mezger J, Ramlau R, Moore N et al (2010) Efficacy and safety of bevacizumab-based therapy in elderly patients with advanced or recurrent nonsquamous non-small cell lung cancer in the phase III BO17704 study (AVAiL). J Thorac Oncol 5:1970-1976
-
(2010)
J Thorac Oncol
, vol.5
, pp. 1970-1976
-
-
Leighl, N.B.1
Zatloukal, P.2
Mezger, J.3
Ramlau, R.4
Moore, N.5
-
28
-
-
84555206070
-
Safety and efficacy of first-line bevacizumab plus chemotherapy in elderly patients with advanced or recurrent nonsquamous non-small cell lung cancer: Safety of avastin in lung trial (MO19390)
-
22173662 10.1097/JTO.0b013e3182370e02 1:CAS:528:DC%2BC38XjtFKjsL8%3D
-
Laskin J, Crino L, Felip E, Franke F, Gorbunova V et al (2012) Safety and efficacy of first-line bevacizumab plus chemotherapy in elderly patients with advanced or recurrent nonsquamous non-small cell lung cancer: safety of avastin in lung trial (MO19390). J Thorac Oncol 7:203-211
-
(2012)
J Thorac Oncol
, vol.7
, pp. 203-211
-
-
Laskin, J.1
Crino, L.2
Felip, E.3
Franke, F.4
Gorbunova, V.5
-
29
-
-
79960183862
-
Clinical outcomes (CO) for special populations of patients (pts) with advanced non-small cell lung cancer (NSCLC): Results from ARIES, a bevacizumab (BV) observational cohort study (OCS)
-
Wozniak Aa, J; Jahanzeb, M; Kosty, MP; Vidaver, R; Beatty, S; Teng, S; Flick, ED; Sing, A; Lynch, TJ (2010) Clinical outcomes (CO) for special populations of patients (pts) with advanced non-small cell lung cancer (NSCLC): results from ARIES, a bevacizumab (BV) observational cohort study (OCS). J Clin Oncol 28:15s
-
(2010)
J Clin Oncol
, vol.28
-
-
Wozniak, A.A.1
Jahanzeb, J.2
Kosty, M.3
Vidaver, M.P.4
Beatty, R.5
Teng, S.6
Flick, S.7
Sing, E.D.8
Lynch, A.9
-
30
-
-
74949092481
-
Bevacizumab safety in patients with central nervous system metastases
-
20028762 10.1158/1078-0432.CCR-09-2439 1:CAS:528:DC%2BC3cXot1Sj
-
Besse B, Lasserre SF, Compton P, Huang J, Augustus S et al (2010) Bevacizumab safety in patients with central nervous system metastases. Clin Cancer Res 16:269-278
-
(2010)
Clin Cancer Res
, vol.16
, pp. 269-278
-
-
Besse, B.1
Lasserre, S.F.2
Compton, P.3
Huang, J.4
Augustus, S.5
-
31
-
-
70349452141
-
Treatment rationale and study design for the pointbreak study: A randomized, open-label phase III study of pemetrexed/carboplatin/bevacizumab followed by maintenance pemetrexed/bevacizumab versus paclitaxel/carboplatin/ bevacizumab followed by maintenance bevacizumab in patients with stage IIIB or IV nonsquamous non-small-cell lung cancer
-
19632943 10.3816/CLC.2009.n.035 1:CAS:528:DC%2BD1MXhtVSms7nJ
-
Patel JD, Bonomi P, Socinski MA, Govindan R, Hong S et al (2009) Treatment rationale and study design for the pointbreak study: a randomized, open-label phase III study of pemetrexed/carboplatin/bevacizumab followed by maintenance pemetrexed/bevacizumab versus paclitaxel/carboplatin/bevacizumab followed by maintenance bevacizumab in patients with stage IIIB or IV nonsquamous non-small-cell lung cancer. Clin Lung Cancer 10:252-256
-
(2009)
Clin Lung Cancer
, vol.10
, pp. 252-256
-
-
Patel, J.D.1
Bonomi, P.2
Socinski, M.A.3
Govindan, R.4
Hong, S.5
-
32
-
-
84874936166
-
A randomized, open-label, phase 3, superiority study of pemetrexed (Pem)+carboplatin (Cb)+bevacizumab (B) followed by maintenance Pem+B versus paclitaxel (Pac)+Cb+B followed by maintenance B in patients (pts) with stage IIIB or IV non-squamous non-small cell lung cancer (NS-NSCLC)
-
10.1097/01.JTO.0000419337.45749.bb
-
Patel JS et al (2012) A randomized, open-label, phase 3, superiority study of pemetrexed (Pem)+carboplatin (Cb)+bevacizumab (B) followed by maintenance Pem+B versus paclitaxel (Pac)+Cb+B followed by maintenance B in patients (pts) with stage IIIB or IV non-squamous non-small cell lung cancer (NS-NSCLC). J Thorac Oncol 7:S336
-
(2012)
J Thorac Oncol
, vol.7
, pp. 336
-
-
Patel, J.S.1
-
34
-
-
77957037908
-
Treatment rationale and study design for a randomized trial of pemetrexed/carboplatin followed by maintenance pemetrexed versus paclitaxel/carboplatin/bevacizumab followed by maintenance bevacizumab in patients with advanced non-small-cell lung cancer of nonsquamous histology
-
20837462 10.3816/CLC.2010.n.045 1:CAS:528:DC%2BC3cXht1Kqsb3E
-
Zinner RG, Saxman SB, Peng G, Monberg MJ, Ortuzar WI (2010) Treatment rationale and study design for a randomized trial of pemetrexed/carboplatin followed by maintenance pemetrexed versus paclitaxel/carboplatin/bevacizumab followed by maintenance bevacizumab in patients with advanced non-small-cell lung cancer of nonsquamous histology. Clin Lung Cancer 11:352-357
-
(2010)
Clin Lung Cancer
, vol.11
, pp. 352-357
-
-
Zinner, R.G.1
Saxman, S.B.2
Peng, G.3
Monberg, M.J.4
Ortuzar, W.I.5
-
35
-
-
80155141305
-
Randomized phase IIIb trial evaluating the continuation of bevacizumab beyond disease progression in patients with advanced non-squamous non-small-cell lung cancer after first-line treatment with bevacizumab plus platinum-based chemotherapy: Treatment rationale and protocol dynamics of the AvaALL (MO22097) trial
-
21705281 10.1016/j.cllc.2011.05.002 1:CAS:528:DC%2BC38XitFyntQ%3D%3D
-
Gridelli C, Bennouna J, de Castro J, Dingemans AM, Griesinger F et al (2011) Randomized phase IIIb trial evaluating the continuation of bevacizumab beyond disease progression in patients with advanced non-squamous non-small-cell lung cancer after first-line treatment with bevacizumab plus platinum-based chemotherapy: treatment rationale and protocol dynamics of the AvaALL (MO22097) trial. Clin Lung Cancer 12:407-411
-
(2011)
Clin Lung Cancer
, vol.12
, pp. 407-411
-
-
Gridelli, C.1
Bennouna, J.2
De Castro, J.3
Dingemans, A.M.4
Griesinger, F.5
-
36
-
-
84866152751
-
Bevacizumab (BEV) plus chemotherapy (CT) continued beyond first progression in patients with metastatic colorectal cancer (mCRC) previously treated with BEV plus CT: Results of a randomized phase III intergroup study (TML study)
-
Arnold DA, T; Bennouna, J; Sastre, J; Osterlund, PJ; Greil, R; Van Cutsem, E; Von Moos, IR; Reyes-Rivera, M; Bendahmane, B; Kubicka, S (2012) Bevacizumab (BEV) plus chemotherapy (CT) continued beyond first progression in patients with metastatic colorectal cancer (mCRC) previously treated with BEV plus CT: Results of a randomized phase III intergroup study (TML study). J Clin Oncol 30.
-
(2012)
J Clin Oncol
, vol.30
-
-
Arnold, D.A.1
Bennouna, T.2
Sastre, J.3
Osterlund, J.4
Greil, P.J.5
Van Cutsem, R.6
Von Moos, E.7
Reyes-Rivera, I.R.8
Bendahmane, M.9
Kubicka, B.10
-
37
-
-
84856650490
-
Interim report of on-study demographics and toxicity from E1505, a phase III randomized trial of adjuvant (adj) chemotherapy (chemo) with or without bevacizumab (B) for completely resected early-stage non-small cell lung cancer (NSCLC)
-
Wakelee HD, SE; Keller, SM; Gandara, DR; Graziano, SL; Leighl, NB; Adjei, AA; Schiller, JH (2011) Interim report of on-study demographics and toxicity from E1505, a phase III randomized trial of adjuvant (adj) chemotherapy (chemo) with or without bevacizumab (B) for completely resected early-stage non-small cell lung cancer (NSCLC). J Clin Oncol 29.
-
(2011)
J Clin Oncol
, vol.29
-
-
Wakelee, H.D.1
Keller, S.E.2
Gandara, S.M.3
Graziano, D.R.4
Leighl, S.L.5
Adjei, N.B.6
Schiller, A.A.7
-
38
-
-
84867503535
-
A randomized, double-blind, phase III study of docetaxel and ramucirumab versus docetaxel and placebo in the treatment of stage IV non-small-cell lung cancer after disease progression after 1 previous platinum-based therapy (REVEL): Treatment rationale and study design
-
10.1016/j.cllc.2012.06.007 1:CAS:528:DC%2BC38XhsFSlt7jP
-
Garon EB, Cao D, Alexandris E, John WJ, Yurasov S et al (2012) A randomized, double-blind, phase III study of docetaxel and ramucirumab versus docetaxel and placebo in the treatment of stage IV non-small-cell lung cancer after disease progression after 1 previous platinum-based therapy (REVEL): treatment rationale and study design. Clin Lung Cancer 13:505-509
-
(2012)
Clin Lung Cancer
, vol.13
, pp. 505-509
-
-
Garon, E.B.1
Cao, D.2
Alexandris, E.3
John, W.J.4
Yurasov, S.5
-
39
-
-
84874934368
-
Aflibercept in combination with do-cetaxel for second-line treatment of locally advanced or metastatic non-small-cell lung cancer (NSCLC): Final results of a multinational placebo-controlled phase III trial (EFC10261-VITAL)
-
Novello SR, R; Gorbunova, VA (2011) Aflibercept in combination with do-cetaxel for second-line treatment of locally advanced or metastatic non-small-cell lung cancer (NSCLC): final results of a multinational placebo-controlled phase III trial (EFC10261-VITAL). WCLC 2011.
-
(2011)
WCLC 2011
-
-
Novello, S.R.1
Gorbunova, R.2
-
40
-
-
84857428285
-
Safety profile and tolerability of antiangiogenic agents in non-small-cell lung cancer
-
22056889 10.1016/j.cllc.2011.08.006 1:CAS:528:DC%2BC38XislSrsbo%3D
-
Gadgeel SM (2012) Safety profile and tolerability of antiangiogenic agents in non-small-cell lung cancer. Clin Lung Cancer 13:96-106
-
(2012)
Clin Lung Cancer
, vol.13
, pp. 96-106
-
-
Gadgeel, S.M.1
-
41
-
-
84865487963
-
Beyond bevacizumab: Antiangiogenic agents
-
22297207 10.1016/j.cllc.2011.12.001 1:CAS:528:DC%2BC38Xht1GksbvJ
-
Rogosin S, Sandler AB (2012) Beyond bevacizumab: antiangiogenic agents. Clin Lung Cancer 13:326-333
-
(2012)
Clin Lung Cancer
, vol.13
, pp. 326-333
-
-
Rogosin, S.1
Sandler, A.B.2
-
42
-
-
84865095318
-
International, randomized, placebo-controlled, double-blind phase III study of motesanib plus carboplatin/paclitaxel in patients with advanced nonsquamous non-small-cell lung cancer: MONET1
-
22753922 10.1200/JCO.2011.41.4987 1:CAS:528:DC%2BC38Xhtlygu7zI
-
Scagliotti GV, Vynnychenko I, Park K, Ichinose Y, Kubota K et al (2012) International, randomized, placebo-controlled, double-blind phase III study of motesanib plus carboplatin/paclitaxel in patients with advanced nonsquamous non-small-cell lung cancer: MONET1. J Clin Oncol 30:2829-2836
-
(2012)
J Clin Oncol
, vol.30
, pp. 2829-2836
-
-
Scagliotti, G.V.1
Vynnychenko, I.2
Park, K.3
Ichinose, Y.4
Kubota, K.5
-
43
-
-
84865721505
-
Phase III, randomized, double-blind, placebo-controlled trial of gemcitabine/cisplatin alone or with sorafenib for the first-line treatment of advanced, nonsquamous non-small-cell lung cancer
-
22851564 10.1200/JCO.2011.39.7646 1:CAS:528:DC%2BC38XhsVKlsLnO
-
Paz-Ares LG, Biesma B, Heigener D, von Pawel J, Eisen T et al (2012) Phase III, randomized, double-blind, placebo-controlled trial of gemcitabine/cisplatin alone or with sorafenib for the first-line treatment of advanced, nonsquamous non-small-cell lung cancer. J Clin Oncol 30:3084-3092
-
(2012)
J Clin Oncol
, vol.30
, pp. 3084-3092
-
-
Paz-Ares, L.G.1
Biesma, B.2
Heigener, D.3
Von Pawel, J.4
Eisen, T.5
-
44
-
-
73949092851
-
Randomized, double-blind trial of carboplatin and paclitaxel with either daily oral cediranib or placebo in advanced non-small-cell lung cancer: NCIC clinical trials group BR24 study
-
19917841 10.1200/JCO.2009.22.9427 1:CAS:528:DC%2BC3cXhtF2ku7Y%3D
-
Goss GD, Arnold A, Shepherd FA, Dediu M, Ciuleanu TE et al (2010) Randomized, double-blind trial of carboplatin and paclitaxel with either daily oral cediranib or placebo in advanced non-small-cell lung cancer: NCIC clinical trials group BR24 study. J Clin Oncol 28:49-55
-
(2010)
J Clin Oncol
, vol.28
, pp. 49-55
-
-
Goss, G.D.1
Arnold, A.2
Shepherd, F.A.3
Dediu, M.4
Ciuleanu, T.E.5
-
45
-
-
79957452054
-
A phase II double-blind study to investigate efficacy and safety of two doses of the triple angiokinase inhibitor BIBF 1120 in patients with relapsed advanced non-small-cell lung cancer
-
21212157 10.1093/annonc/mdq618 1:STN:280:DC%2BC3MrkvFyhtw%3D%3D
-
Reck M, Kaiser R, Eschbach C, Stefanic M, Love J et al (2011) A phase II double-blind study to investigate efficacy and safety of two doses of the triple angiokinase inhibitor BIBF 1120 in patients with relapsed advanced non-small-cell lung cancer. Ann Oncol 22:1374-1381
-
(2011)
Ann Oncol
, vol.22
, pp. 1374-1381
-
-
Reck, M.1
Kaiser, R.2
Eschbach, C.3
Stefanic, M.4
Love, J.5
-
46
-
-
80051638135
-
Randomized phase III placebo-controlled trial of carboplatin and paclitaxel with or without the vascular disrupting agent vadimezan (ASA404) in advanced non-small-cell lung cancer
-
21709202 10.1200/JCO.2011.35.0660 1:CAS:528:DC%2BC3MXhtFCqtLbO
-
Lara PN Jr, Douillard JY, Nakagawa K, von Pawel J, McKeage MJ et al (2011) Randomized phase III placebo-controlled trial of carboplatin and paclitaxel with or without the vascular disrupting agent vadimezan (ASA404) in advanced non-small-cell lung cancer. J Clin Oncol 29:2965-2971
-
(2011)
J Clin Oncol
, vol.29
, pp. 2965-2971
-
-
Lara, Jr.P.N.1
Douillard, J.Y.2
Nakagawa, K.3
Von Pawel, J.4
McKeage, M.J.5
-
48
-
-
84856837903
-
EGFL7: A unique angiogenic signaling factor in vascular development and disease
-
22160377 10.1182/blood-2011-10-322446 1:CAS:528:DC%2BC38XjtVSrsr8%3D
-
Nichol D, Stuhlmann H (2012) EGFL7: a unique angiogenic signaling factor in vascular development and disease. Blood 119:1345-1352
-
(2012)
Blood
, vol.119
, pp. 1345-1352
-
-
Nichol, D.1
Stuhlmann, H.2
-
49
-
-
84859795317
-
Targeting the Met pathway in lung cancer
-
22500688 10.1586/era.12.16 1:CAS:528:DC%2BC38Xls1Sgtb8%3D
-
Belalcazar A, Azana D, Perez CA, Raez LE, Santos ES (2012) Targeting the Met pathway in lung cancer. Expert Rev Anticancer Ther 12:519-528
-
(2012)
Expert Rev Anticancer Ther
, vol.12
, pp. 519-528
-
-
Belalcazar, A.1
Azana, D.2
Perez, C.A.3
Raez, L.E.4
Santos, E.S.5
|