Comparison of the value of PCNA and Ki-67 as markers of cell proliferation in ameloblastic tumors

Medicina Oral, Patologia Oral y Cirugia Bucal

Volumn 18, Issue 2, 2013, Pages

  Bologna Molina, Ronell ^a,b   Mosqueda Taylor, Adalberto ^c   Molina Frechero, Nelly ^c   Mori Estevez, Ana Dolores ^d   Sánchez Acuña, Guillermo ^d  

^a UNIVERSIDAD JUÁREZ DEL ESTADO DE DURANGO   (Mexico)

^b UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^c DEPARTAMENTO DE SISTEMAS BIOLÓGICOS   (Mexico)

^d Hospital Universitario 'Gral Calixto Garcia'   (Cuba)

Author keywords

Ameloblastic carcinoma; Ameloblastomas; Cell proliferation markers; Ki 67; PCNA

Indexed keywords

CYCLINE; KI 67 ANTIGEN;

AMELOBLASTOMA; ARTICLE; CELL PROLIFERATION; DESCRIPTIVE RESEARCH; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; OBSERVATIONAL STUDY; RETROSPECTIVE STUDY;

AMELOBLASTOMA; BIOLOGICAL MARKERS; CELL PROLIFERATION; HUMANS; KI-67 ANTIGEN; MOUTH NEOPLASMS; PROLIFERATING CELL NUCLEAR ANTIGEN; RETROSPECTIVE STUDIES;

EID: 84874925544     PISSN: 16984447     EISSN: 16986946     Source Type: Journal    
DOI: 10.4317/medoral.18573     Document Type: Article

References (29)

1. Van Diest PJ, Brugal G, Baak JP. Proliferation markers in tumours: interpretation and clinical value. J Clin Pathol.1998;51:716-24.
2. Bishop JM. The molecular genetics of cancer. Science. 1987;235:305-11.
3. Tumuluri V, Thomas GA, Fraser IS. Analysis of the Ki-67 antigen at the invasive tumour front of human oral squamous cell carcinoma. J Oral Pathol Med. 2002;31:598-604.
4. Scully C, Field JK, Tanzawa H. Genetic aberrations in oral or head and neck squamous cell carcinoma (SCCHN): 1. Carcinogen metabolism, DNA repair and cell cycle control. Oral Oncol. 2000;36:256-63.
5. Gerdes J, Schwab U, Lemke H, Stein H. Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int J Cancer. 1983;31:13-20.
6. Ihmann T, Liu J, Schwabe W, Häusler P, Behnke D, Bruch HP, et al. High-level mRNA quantification of proliferation marker pKi-67 is correlated with favorable prognosis in colorectal carcinoma. J Cancer Res Clin Oncol. 2004;130:749-56.
7. Kelman Z. PCNA: structure, functions and interactions. Oncogene. 1997;14:629-40.
8. de Oliveira MG, Lauxen Ida S, Chaves AC, Rados PV, Sant'AnaFilho M. Immunohistochemical analysis of the patterns of p53 and PCNA expression in odontogenic cystic lesions. Med Oral Patol Oral Cir Bucal. 2008;13:E275-80.
9. Mighell A. PCNA and p53. Eur J Cancer B Oral Oncol. 1995;31B:403-4.
10. De Biasio A, Sánchez R, Prieto J, Villate M, Campos-Olivas R, Blanco FJ. Reduced stability and increased dynamics in the human proliferating cell nuclear antigen (PCNA) relative to the yeast homolog. PLoS One. 2011;6:e16600.
11. Oka S, Uramoto H, Shimokawa H, Iwanami T, Tanaka F. The expression of Ki-67, but not proliferating cell nuclear antigen, predicts poor disease free survival in patients with adenocarcinoma of the lung. Anticancer Res. 2011;31:4277-82.
12. Mateoiu C, Pirici A, Bogdan F. Immunohistochemical nuclear staining for p53, PCNA, Ki-67 and bcl-2 in different histologic variants of basal cell carcinoma. Rom J Morphol Embryol. 2011;52:315-9.
13. Salehinejad J, Zare-Mahmoodabadi R, Saghafi S, Jafarian AH, Ghazi N, Rajaei AR, et al. Immunohistochemical detection of p53 and PCNA in ameloblastoma and adenomatoidodontogenic tumor. J Oral Sci. 2011;53:213-7.
14. Saghafi S, Zare-Mahmoodabadi R, Salehinejad J, Kadeh H, Afzal-Aghaee M. Immunohistochemical analysis of p53 and PCNA expression in calcifying odontogenic cyst. J Oral Sci. 2010;52:609-13.
15. Ahmed MM, El-Azab SM. Evaluation of cell cycle-related indicators in plexiform ameloblastoma. J Egypt Natl Canc Inst. 2008;20:294-301.
16. Figueroa A, Correnti M, Avila M, Andea A, DeVilliers P, Rivera H. Keratocystic odontogenic tumor associated with nevoid basal cell carcinoma syndrome: similar behavior to sporadic type?. Otolaryngol Head Neck Surg. 2010;142:179-83.
17. Myoung H, Kim MJ, Lee JH, Ok YJ, Paeng JY, Yun PY. Correlation of proliferative markers (Ki-67 and PCNA) with survival and lymph node metastasis in oral squamous cell carcinoma: a clinical and histopathological analysis of 113 patients. Int J Oral Maxillofac Surg. 2006;35:1005-10.
18. Pontes HA, Pontes FS, Silva BS, Cury SE, Fonseca FP, Salim RA, et al. Immunoexpression of Ki67, proliferative cell nuclear antigen, and Bcl-2 proteins in a case of ameloblastic fibrosarcoma. Ann Diagn Pathol. 2010;14:447-52.
19. Barnes L, Eveson JW, Reichart P, Sidransky D.: World health organization classification of tumors. Pathology and genetics head and neck tumors. (eds). Lyon: IARC Press;2005.
20. Bologna-Molina R, Damián-Matsumura P, Molina-Frechero N. An easy cell counting method for immunohistochemistry that does not use an image analysis program. Histopathology. 2011;59:801-3.
21. Meer S, Galpin JS, Altini M, Coleman H, Ali H. Proliferating cell nuclear antigen and Ki67 immunoreactivity in ameloblastomas. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003;95:213-21.
22. Sandra F, Mitsuyasu T, Nakamura N, Shiratsuchi Y, Ohishi M. Immunohistochemical evaluation of PCNA and Ki-67 in ameloblastoma. Oral Oncol. 2001;37:193-8.
23. Li TJ, Browne RM, Matthews JB. Expression of proliferating cell nuclear antigen (PCNA) and Ki-67 in unicystic ameloblastoma. Histopathology. 1995;26:219-28.
24. Liu M, Lawson G, Delos M, Jamart J, Ide C, Coche E, et al. Predictive value of the fraction of cancer cells immunolabeled for proliferating cell nuclear antigen or Ki-67 in biopsies of head and neck carcinomas to identify lymph node metastasis: comparison with clinical and radiologic examinations. Head Neck. 2003;25:280-8.
25. Bologna-Molina R, Mosqueda-Taylor A, Lopez-Corella E, Almeida OP, Carrasco-Daza D, Garcia-Vazquez F, et al. Syndecan-1 (CD138) and Ki-67 expression in different subtypes ameloblastomas. Oral Oncol. 2008;44:805-11.
26. Mighell A. Proliferating cell nuclear antigen. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1995;80:3-4.
27. Otali D, Stockard CR, Oelschlager DK, Wan W, Manne U, Watts SA, et al. Combined effects of formalin fixation and tissue processing on immunorecognition. Biotech Histochem. 2009;84:223-47.
28. Scholzen T, Gerdes J. The Ki-67 protein: from the known and the unknown. J Cell Physiol. 2000;182:311-22.
29. Heidebrecht HJ, Buck F, Haas K, Wacker HH, Parwaresch R. Monoclonal antibodies Ki-S3 and Ki-S5 yield new data on the "Ki-67" proteins. Cell Prolif. 1996;29:413-425.