Genotype-specific patterns of atrophy progression are more sensitive than clinical decline in SCA1, SCA3 and SCA6

Brain

Volumn 136, Issue 3, 2013, Pages 905-917

  Reetz, Kathrin ^a,b,c   Costa, Ana S ^a   Mirzazade, Shahram ^a,b,c   Lehmann, Anna ^a,d   Juzek, Agnes ^a   Rakowicz, Maria ^e   Boguslawska, Romana ^f   Schöls, Ludger ^g,h   Linnemann, Christoph ^g,i   Mariotti, Caterina ^j   Grisoli, Marina ^j   Dürr, Alexandra ^k   Van De Warrenburg, Bart P ^l   Timmann, Dagmar ^m   Pandolfo, Massimo ⁿ   Bauer, Peter ^o   Jacobi, Heike ^p   Hauser, Till Karsten ^o   Klockgether, Thomas ^h,p   Schulz, Jörg B ^a,c  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b FORSCHUNGSZENTRUM JÜLICH   (Germany)

^c Julich Aachen Research Alliance JARA   (Germany)

^d LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^e INSTITUTE OF PSYCHIATRY AND NEUROLOGY   (Poland)

^f MILITARY INSTITUTE OF MEDICINE   (Poland)

^g UNIVERSITY OF TÜBINGEN   (Germany)

^h GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

ⁱ UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

^j DEPARTMENT OF NEUROSURGERY   (Italy)

^k INSERM   (France)

^l RADBOUD UNIVERSITY   (Netherlands)

^m UNIVERSITY OF DUISBURG ESSEN   (Germany)

ⁿ ERASME HOSPITAL   (Belgium)

^o UNIVERSITY OF TÜBINGEN   (Germany)

^p UNIVERSITY HOSPITAL BONN   (Germany)

more..

Author keywords

atrophy; neurodegeneration; spinocerebellar ataxia; volumetry; voxel based morphometry

Indexed keywords

ATAXIN 1; ATAXIN 3;

ADULT; ARTICLE; BASAL GANGLION; BRAIN ATROPHY; BRAIN SIZE; BRAIN STEM; CAG REPEAT; CAUDATE NUCLEUS; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DISEASE COURSE; FEMALE; GENE; GENOTYPE; GLOBUS PALLIDUS; GRAY MATTER; HUMAN; MALE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PONS; PRIORITY JOURNAL; PUTAMEN; QUANTITATIVE ANALYSIS; RATING SCALE; SCALE FOR THE ASSESSMENT AND RATING OF ATAXIA; SPINOCEREBELLAR ATAXIA 1 GENE; SPINOCEREBELLAR ATAXIA 3 GENE; SPINOCEREBELLAR ATAXIA 6 GENE; SPINOCEREBELLAR DEGENERATION; VOLUMETRY; VOXEL BASED MORPHOMETRY;

EID: 84874913811     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/aws369     Document Type: Article

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