Probing arginine side-chains and their dynamics with carbon-detected NMR spectroscopy: Application to the 42 kDa human histone deacetylase 8 at high pH

Angewandte Chemie - International Edition

Volumn 52, Issue 11, 2013, Pages 3145-3147

  Werbeck, Nicolas D ^a   Kirkpatrick, John ^a   Hansen, D Flemming ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

arginine; histone deacetylases; NMR spectroscopy; protein dynamics; spin relaxation

Indexed keywords

CORRELATION SPECTRA; HIGH PH; HISTONE DEACETYLASES; POSITIVE CHARGES; PROTEIN DYNAMICS; SIDE-CHAINS; SPIN RELAXATION;

ARGININE; CARBON; DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

SPIN DYNAMICS;

ARGININE; CARBON; HDAC8 PROTEIN, HUMAN; HISTONE DEACETYLASE; REPRESSOR PROTEIN;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; HUMAN; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE; PH;

ARGININE; CARBON; HISTONE DEACETYLASES; HUMANS; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; REPRESSOR PROTEINS;

EID: 84874909604     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201209385     Document Type: Article

References (28)

1. M. J. Harms, J. L. Schlessman, G. R. Sue, B. García-Moreno, Proc. Natl. Acad. Sci. USA 2011, 108, 18954-18959.
2. A. G. Palmer, C. D. Kroenke, J. P. Loria, Methods Enzymol. 2001, 339, 204-238
3. O. F. Lange, N. A. Lakomek, C. Farès, G. F. Schröder, K. F. Walter, S. Becker, J. Meiler, H. Grubmüller, C. Griesinger, B. L. de Groot, Science 2008, 320, 1471-1475
4. A. K. Gardino, D. Kern, Methods Enzymol. 2007, 423, 149-165.
5. R. B. Best, T. J. Rutherford, S. M. V. Freund, J. Clarke, Biochemistry 2004, 43, 1145-1155
6. A. L. Lee, S. A. Kinnear, A. J. Wand, Nat. Struct. Biol. 2000, 7, 72-77.
7. R. Sprangers, L. E. Kay, Nature 2007, 445, 618-622.
8. J. Iwahara, Y. S. Jung, G. M. Clore, J. Am. Chem. Soc. 2007, 129, 2971-2980
9. R. Paquin, F. Ferrage, F. A. A. Mulder, M. Akke, G. Bodenhausen, J. Am. Chem. Soc. 2008, 130, 15805-15807.
10. I. André, S. Linse, F. A. A. Mulder, J. Am. Chem. Soc. 2007, 129, 15805-15813.
11. G. Lipari, A. Szabo, J. Am. Chem. Soc. 1982, 104, 4546-4559
12. N. Trbovic, J.-H. Cho, R. Abel, R. A. Friesner, M. Rance, A. G. Palmer, J. Am. Chem. Soc. 2009, 131, 615-622.
13. H. Geen, R. Freeman, J. Magn. Reson. 1991, 93, 93-141.
14. J. M. Bohlen, G. Bodenhausen, J. Magn. Reson. Ser. A 1993, 102, 293-301.
15. Z. Zhou, R. Kümmerle, X. Qiu, D. Redwine, R. Cong, A. Taha, D. Baugh, B. Winniford, J. Magn. Reson. 2007, 187, 225-233.
16. A. J. Shaka, P. B. Barker, R. Freeman, J. Magn. Reson. 1985, 64, 547-552.
17. F. A. A. Mulder, B. Hon, D. R. Muhandiram, F. W. Dahlquist, L. E. Kay, Biochemistry 2000, 39, 12614-12622.
18. A. E. Eriksson, W. A. Baase, B. W. J. Matthews, J. Mol. Biol. 1993, 229, 747-769.
19. S. Grzesiek, J. Anglister, A. Bax, J. Magn. Reson. Ser. B 1993, 101, 114-119.
20. R. B. Best, J. Clarke, M. Karplus, J. Am. Chem. Soc. 2004, 126, 7734-7735.
21. N. A. Farrow, R. Muhandiram, A. U. Singer, S. M. Pascal, C. M. Kay, G. Gish, S. E. Shoelson, T. Pawson, J. D. Forman-Kay, L. E. Kay, Biochemistry 1994, 33, 5984-6003.
22. S. Minucci, P. G. Pelicci, Nat. Rev. Cancer 2006, 6, 38-51.
23. S. Haider, C. G. Joseph, S. Neidle, C. A. Fierke, M. J. Fuchter, Bioorg. Med. Chem. Lett. 2011, 21, 2129-2132.
24. S. L. Gantt, C. G. Joseph, C. A. Fierke, J. Biol. Chem. 2010, 285, 6036-6043.
25. A. Vannini, C. Volpari, P. Gallinari, P. Jones, M. Mattu, A. Carfí, R. De Francesco, C. Steinkühler, S. Di Marco, EMBO Rep. 2007, 8, 879-884.
26. I. Gelis, A. M. J. J. Bonvin, D. Keramisanou, M. Koukaki, G. Gouridis, S. Karamanou, A. Economou, C. G. Kalodimos, Cell 2007, 131, 756-769.
27. F. Delaglio, S. Grzesiek, G. W. Vuister, G. Zhu, J. Pfeifer, A. Bax, J. Biomol. NMR 1995, 6, 277-293.
28. D. F. Hansen, D. Yang, H. Feng, Z. Zhou, S. Wiesner, Y. Bai, L. E. Kay, J. Am. Chem. Soc. 2007, 129, 11468-11479.