-
1
-
-
0034958947
-
Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
-
Angus DC, Linde-Zwirble WT, Lidicker J, et al.: Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care. Crit Care Med 2001; 29:1303-1310
-
(2001)
Crit Care Med
, vol.29
, pp. 1303-1310
-
-
Angus, D.C.1
Linde-Zwirble, W.T.2
Lidicker, J.3
-
2
-
-
0035159740
-
Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: A multicenter, randomized, placebo-controlled, single-blind, dose escalation study
-
Abraham E, Reinhart K, Svoboda P, et al.: Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: A multicenter, randomized, placebo-controlled, single-blind, dose escalation study. Crit Care Med 2001; 29:2081-2089
-
(2001)
Crit Care Med
, vol.29
, pp. 2081-2089
-
-
Abraham, E.1
Reinhart, K.2
Svoboda, P.3
-
3
-
-
1242337462
-
New treatment strategies for disseminated intravascular coagulation based on current understanding of the pathophysiology
-
Levi M, de Jonge E, van der Poll T: New treatment strategies for disseminated intravascular coagulation based on current understanding of the pathophysiology. Ann Med 2004; 36:41-49
-
(2004)
Ann Med
, vol.36
, pp. 41-49
-
-
Levi, M.1
De Jonge, E.2
Van Der Poll, T.3
-
4
-
-
0028896007
-
Mechanism of antithrombin III inhibition of factor VIIa/tissue factor activity on cell surfaces. Comparison with tissue factor pathway inhibitor/factor Xa-induced inhibition of factor VIIa/tissue factor activity
-
Rao LV, Nordfang O, Hoang AD, et al.: Mechanism of antithrombin III inhibition of factor VIIa/tissue factor activity on cell surfaces. Comparison with tissue factor pathway inhibitor/factor Xa-induced inhibition of factor VIIa/tissue factor activity. Blood 1995; 85:121-129
-
(1995)
Blood
, vol.85
, pp. 121-129
-
-
Rao, L.V.1
Nordfang, O.2
Hoang, A.D.3
-
5
-
-
0036910608
-
Antithrombin: A new look at the actions of a serine protease inhibitor
-
Roemisch J, Gray E, Hoffmann JN, et al.: Antithrombin: A new look at the actions of a serine protease inhibitor. Blood Coagul Fibrinolysis 2002; 13:657-670
-
(2002)
Blood Coagul Fibrinolysis
, vol.13
, pp. 657-670
-
-
Roemisch, J.1
Gray, E.2
Hoffmann, J.N.3
-
6
-
-
33748428053
-
Microcirculatory disorders in sepsis and transplantation: Therapy with natural coagulatory inhibitors antithrombin and activated protein C
-
Hoffmann JN, Fertmann JM, Jauch K W: Microcirculatory disorders in sepsis and transplantation: Therapy with natural coagulatory inhibitors antithrombin and activated protein C. Curr Opin Crit Care 2006; 12: 426-430
-
(2006)
Curr Opin Crit Care
, vol.12
, pp. 426-430
-
-
Hoffmann, J.N.1
Fertmann, J.M.2
Jauch, K.W.3
-
7
-
-
0036625064
-
Antithrombin III inhibits nuclear factor kappaB activation in human monocytes and vascular endothelial cells
-
Oelschläger C, Römisch J, Staubitz A, et al.: Antithrombin III inhibits nuclear factor kappaB activation in human monocytes and vascular endothelial cells. Blood 2002; 99:4015-4020
-
(2002)
Blood
, vol.99
, pp. 4015-4020
-
-
Oelschläger, C.1
Römisch, J.2
Staubitz, A.3
-
8
-
-
0036155210
-
Antithrombin effects on endotoxin-induced microcirculatory disorders are mediated mainly by its interaction with microvascular endothelium
-
Hoffmann JN, Vollmar B, Römisch J, et al.: Antithrombin effects on endotoxin-induced microcirculatory disorders are mediated mainly by its interaction with microvascular endothelium. Crit Care Med 2002; 30:218-225
-
(2002)
Crit Care Med
, vol.30
, pp. 218-225
-
-
Hoffmann, J.N.1
Vollmar, B.2
Römisch, J.3
-
9
-
-
0033197834
-
In vivo analysis of microcirculation following closed soft-tissue injury
-
Schaser KD, Vollmar B, Menger MD, et al.: In vivo analysis of microcirculation following closed soft-tissue injury. J Orthop Res 1999; 17: 678-685
-
(1999)
J Orthop Res
, vol.17
, pp. 678-685
-
-
Schaser, K.D.1
Vollmar, B.2
Menger, M.D.3
-
10
-
-
0026062640
-
A controlled cortical impact model of traumatic brain injury in the rat
-
Dixon CE, Clifton GL, Lighthall JW, et al: A controlled cortical impact model of traumatic brain injury in the rat. J Neurosci Methods 1991; 39:253-262
-
(1991)
J Neurosci Methods
, vol.39
, pp. 253-262
-
-
Dixon, C.E.1
Clifton, G.L.2
Lighthall, J.W.3
-
12
-
-
0026247341
-
A new preparation of rat extensor digitorum longus muscle for intravital investigation of the microcirculation
-
Tyml K, Budreau CH: A new preparation of rat extensor digitorum longus muscle for intravital investigation of the microcirculation. Int J Microcirc Clin Exp 1991; 10:335-343
-
(1991)
Int J Microcirc Clin Exp
, vol.10
, pp. 335-343
-
-
Tyml, K.1
Budreau, C.H.2
-
13
-
-
0037275611
-
Small volume hypertonic hydroxyethyl starch reduces acute microvascular dysfunction after closed soft-tissue trauma
-
Mittlmeier T, Vollmar B, Menger MD, et al.: Small volume hypertonic hydroxyethyl starch reduces acute microvascular dysfunction after closed soft-tissue trauma. J Bone Joint Surg Br 2003; 85:126-132
-
(2003)
J Bone Joint Surg Br
, vol.85
, pp. 126-132
-
-
Mittlmeier, T.1
Vollmar, B.2
Menger, M.D.3
-
14
-
-
11844265847
-
Selective cyclooxygenase-2 inhibition reverses microcirculatory and inflammatory sequelae of closed softtissue trauma in an animal model
-
Gierer P, Mittlmeier T, Bordel R, et al.: Selective cyclooxygenase-2 inhibition reverses microcirculatory and inflammatory sequelae of closed softtissue trauma in an animal model. J Bone Joint Surg Am 2005; 87: 153-160
-
(2005)
J Bone Joint Surg Am
, vol.87
, pp. 153-160
-
-
Gierer, P.1
Mittlmeier, T.2
Bordel, R.3
-
15
-
-
0027437976
-
Transient analysis of macromolecular transport across microvascular wall and into interstitium
-
Kim D, Armenante PM, Durán W N: Transient analysis of macromolecular transport across microvascular wall and into interstitium. Am J Physiol 1993; 265(3 Pt 2):H993-H999
-
(1993)
Am J Physiol
, vol.265
, Issue.3 PART 2
-
-
Kim, D.1
Armenante, P.M.2
Durán, W.N.3
-
16
-
-
0031239425
-
High-resolution microscopic determination of hepatic NADH fluorescence for in vivo monitoring of tissue oxygenation during hemorrhagic shock and resuscitation
-
Vollmar B, Burkhardt M, Minor T, et al.: High-resolution microscopic determination of hepatic NADH fluorescence for in vivo monitoring of tissue oxygenation during hemorrhagic shock and resuscitation. Microvasc Res 1997; 54:164-173
-
(1997)
Microvasc Res
, vol.54
, pp. 164-173
-
-
Vollmar, B.1
Burkhardt, M.2
Minor, T.3
-
17
-
-
0000613615
-
Intracellular oxidation-reduction states in vivo
-
Chance B, Cohen P, Jobsis F, et al.: Intracellular oxidation-reduction states in vivo. Science 1962; 137:499-508
-
(1962)
Science
, vol.137
, pp. 499-508
-
-
Chance, B.1
Cohen, P.2
Jobsis, F.3
-
18
-
-
0037232991
-
Ischemic preconditioning protects from hepatic ischemia/reperfusion- injury by preservation of microcirculation and mitochondrial redox-state
-
Glanemann M, Vollmar B, Nussler AK, et al.: Ischemic preconditioning protects from hepatic ischemia/reperfusion-injury by preservation of microcirculation and mitochondrial redox-state. J Hepatol 2003; 38:59-66
-
(2003)
J Hepatol
, vol.38
, pp. 59-66
-
-
Glanemann, M.1
Vollmar, B.2
Nussler, A.K.3
-
19
-
-
0037944105
-
Antithrombin reduces ischemia/reperfusion-induced renal injury in rats by inhibiting leukocyte activation through promotion of prostacyclin production
-
Mizutani A, Okajima K, Uchiba M, et al.: Antithrombin reduces ischemia/reperfusion-induced renal injury in rats by inhibiting leukocyte activation through promotion of prostacyclin production. Blood 2003; 101: 3029-3036
-
(2003)
Blood
, vol.101
, pp. 3029-3036
-
-
Mizutani, A.1
Okajima, K.2
Uchiba, M.3
-
20
-
-
0037324153
-
Recombinant antithrombin attenuates pulmonary inflammation following smoke inhalation and pneumonia in sheep
-
Murakami K, McGuire R, Cox RA, et al.: Recombinant antithrombin attenuates pulmonary inflammation following smoke inhalation and pneumonia in sheep. Crit Care Med 2003; 31:577-583
-
(2003)
Crit Care Med
, vol.31
, pp. 577-583
-
-
Murakami, K.1
McGuire, R.2
Cox, R.A.3
-
21
-
-
33748602905
-
Antithrombin is as effective as heparin and hirudin to prevent formation of microvascular thrombosis in a murine model
-
Sorg H, Hoffmann JN, Menger MD, et al.: Antithrombin is as effective as heparin and hirudin to prevent formation of microvascular thrombosis in a murine model. Thromb Haemost 2006; 96:371-377
-
(2006)
Thromb Haemost
, vol.96
, pp. 371-377
-
-
Sorg, H.1
Hoffmann, J.N.2
Menger, M.D.3
-
22
-
-
36248961109
-
Efficacy of antithrombin in the prevention of microvascular thrombosis during endotoxemia: An intravital microscopic study
-
Sorg H, Hoffmann JN, Rumbaut RE, et al.: Efficacy of antithrombin in the prevention of microvascular thrombosis during endotoxemia: An intravital microscopic study. Thromb Res 2007; 121:241-248
-
(2007)
Thromb Res
, vol.121
, pp. 241-248
-
-
Sorg, H.1
Hoffmann, J.N.2
Rumbaut, R.E.3
-
23
-
-
0036153542
-
Syndecan-4 mediates antithrombin-induced chemotaxis of human peripheral blood lymphocytes and monocytes
-
Kaneider NC, Reinisch CM, Dunzendorfer S, et al.: Syndecan-4 mediates antithrombin-induced chemotaxis of human peripheral blood lymphocytes and monocytes. J Cell Sci 2002; 115(Pt 1):227-236
-
(2002)
J Cell Sci
, vol.115
, Issue.PART 1
, pp. 227-236
-
-
Kaneider, N.C.1
Reinisch, C.M.2
Dunzendorfer, S.3
-
24
-
-
0031825290
-
Antithrombin III in patients with severe sepsis. A randomized, placebo-controlled, double-blind multicenter trial plus a meta-analysis on all randomized, placebo-controlled, double-blind trials with antithrombin III in severe sepsis
-
Eisele B, Lamy M, Thijs LG, et al.: Antithrombin III in patients with severe sepsis. A randomized, placebo-controlled, double-blind multicenter trial plus a meta-analysis on all randomized, placebo-controlled, double-blind trials with antithrombin III in severe sepsis. Intensive Care Med 1998; 24:663-672
-
(1998)
Intensive Care Med
, vol.24
, pp. 663-672
-
-
Eisele, B.1
Lamy, M.2
Thijs, L.G.3
-
25
-
-
0035904368
-
Caring for the critically ill patient. Highdose antithrombin III in severe sepsis: A randomized controlled trial
-
Warren BL, Eid A, Singer P, et al.: Caring for the critically ill patient. Highdose antithrombin III in severe sepsis: A randomized controlled trial. JAMA 2001; 286:1869-1878
-
(2001)
JAMA
, vol.286
, pp. 1869-1878
-
-
Warren, B.L.1
Eid, A.2
Singer, P.3
-
26
-
-
37549020378
-
Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock. 2008
-
Dellinger RP, Levy MM, Carlet JM, et al.: Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 2008; 36:296-327
-
(2008)
Crit Care Med
, vol.36
, pp. 296-327
-
-
Dellinger, R.P.1
Levy, M.M.2
Carlet, J.M.3
-
27
-
-
33644859949
-
Treatment effects of high-dose antithrombin without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation
-
Kienast J, Juers M, Wiedermann CJ, et al.: Treatment effects of high-dose antithrombin without concomitant heparin in patients with severe sepsis with or without disseminated intravascular coagulation. J Thromb Haemost 2006; 4:90-97
-
(2006)
J Thromb Haemost
, vol.4
, pp. 90-97
-
-
Kienast, J.1
Juers, M.2
Wiedermann, C.J.3
-
28
-
-
43049131137
-
Sublethal trauma model with systemic endotoxemia for the study of microcirculatory disorders after the second hit
-
Gierer P, Hoffmann JN, Mahr F, et al.: Sublethal trauma model with systemic endotoxemia for the study of microcirculatory disorders after the second hit. J Surg Res 2008; 147:68-74
-
(2008)
J Surg Res
, vol.147
, pp. 68-74
-
-
Gierer, P.1
Hoffmann, J.N.2
Mahr, F.3
-
30
-
-
84860235381
-
Microcirculatory alterations: Potential mechanisms and implications for therapy
-
De Backer D, Donadello K, Taccone FS, et al.: Microcirculatory alterations: Potential mechanisms and implications for therapy. Ann Intensive Care 2011; 1:27
-
(2011)
Ann Intensive Care
, vol.1
, pp. 27
-
-
De Backer, D.1
Donadello, K.2
Taccone, F.S.3
-
31
-
-
42149084524
-
Endothelial glycocalyx damage during endotoxemia coincides with microcirculatory dysfunction and vascular oxidative stress
-
Marechal X, Favory R, Joulin O, et al.: Endothelial glycocalyx damage during endotoxemia coincides with microcirculatory dysfunction and vascular oxidative stress. Shock 2008; 29:572-576
-
(2008)
Shock
, vol.29
, pp. 572-576
-
-
Marechal, X.1
Favory, R.2
Joulin, O.3
-
32
-
-
59649108575
-
The effect of anticoagulants and the role of thrombin on neutrophil-endothelial cell interactions in septic shock
-
Tsen A, Kirschenbaum LA, LaRow C, et al.: The effect of anticoagulants and the role of thrombin on neutrophil-endothelial cell interactions in septic shock. Shock 2009; 31:120-124
-
(2009)
Shock
, vol.31
, pp. 120-124
-
-
Tsen, A.1
Kirschenbaum, L.A.2
La Row, C.3
|