Kir2.4 surface expression and basal current are affected by heterotrimeric g-proteins

Journal of Biological Chemistry

Volumn 288, Issue 10, 2013, Pages 7420-7429

  Sulaiman, Pyroja ^a   Xu, Ying ^b   Fina, Marie E ^a   Tummala, Shanti R ^a   Ramakrishnan, Hariharasubramanian ^a   Dhingra, Anuradha ^a   Vardi, Noga ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b JINAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BASAL ACTIVITIES; CHANNEL PROTEINS; G PROTEIN; INWARD-RECTIFYING; NEURONAL FUNCTION; POTASSIUM CHANNELS; SURFACE EXPRESSION;

POTASSIUM;

PROTEINS;

G PROTEIN BETA GAMMA; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR2.4; MESSENGER RNA; PERTUSSIS TOXIN; PHOSDUCIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL ASSAY; CELL MEMBRANE; CELL STRAIN HEK293; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RETINA BIPOLAR GANGLION CELL; RNA SEQUENCE; SENSITIVITY ANALYSIS; VOLTAGE CLAMP;

ANIMALS; CELL MEMBRANE; FEMALE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN BETA SUBUNITS; GTP-BINDING PROTEIN GAMMA SUBUNITS; HEK293 CELLS; HETEROTRIMERIC GTP-BINDING PROTEINS; HUMANS; ION CHANNEL GATING; MEMBRANE POTENTIALS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUTATION; OOCYTES; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN BINDING; RETINA; TWO-HYBRID SYSTEM TECHNIQUES; XENOPUS;

EID: 84874839114     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.412791     Document Type: Article

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