Visualization of internalization of functionalized cobalt ferrite nanoparticles and their intracellular fate

International Journal of Nanomedicine

Volumn 8, Issue , 2013, Pages 919-931

  Bregar, Vladimir B ^a   Lojk, Jasna ^a   Šuštar, Vid ^a   Veranič, Peter ^a   Pavlin, Mojca ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

Author keywords

Internalization; Intracellular fate; Magnetic nanoparticles; Scanning electron microscopy; Transmission electron microscopy

Indexed keywords

CLATHRIN; COBALT FERRITE NANOPARTICLE; MAGNETIC NANOPARTICLE; POLYACRYLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CELL VIABILITY; CHO CELL; CONTROLLED STUDY; CYTOPLASM; ENDOCYTOSIS; FLUORESCENCE MICROSCOPY; INTERNALIZATION; MATERIAL COATING; NONHUMAN; PINOCYTOSIS; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY;

INTERNALIZATION; INTRACELLULAR FATE; MAGNETIC NANOPARTICLES; SCANNING ELECTRON MICROSCOPY; TRANSMISSION ELECTRON MICROSCOPY;

ACRYLIC RESINS; ANIMALS; CELL MEMBRANE; CELL PROLIFERATION; CELL SURVIVAL; CHO CELLS; COBALT; CRICETINAE; CRICETULUS; CYTOPLASMIC VESICLES; ENDOCYTOSIS; FERRIC COMPOUNDS; INTRACELLULAR SPACE; METAL NANOPARTICLES; MICROSCOPY, ELECTRON;

EID: 84874836876     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S38749     Document Type: Article

References (58)

1. Stone V, Johnston H, Clift MJ. Air pollution, ultrafine and nanoparticle toxicology: cellular and molecular interactions. IEEE Trans Nanobioscience. 2007;6(4):331-340.
2. Oberdörster G, Oberdörster E, Oberdörster J. Nanotoxicology: An emerging discipline evolving from studies of ultrafine particles. Environ Health Perspect. 2005;113(7):823-839.
3. Salata O. Applications of nanoparticles in biology and medicine. J Nanobiotechnology. 2004;2(1):3.
4. Zhang L, Gu FX, Chan JM, Wang AZ, Langer RS, Farokhzad OC. Nanoparticles in medicine: therapeutic applications and developments. Clin Pharmacol Ther. 2008;83(5):761-769.
5. De M, Ghosh PS, Rotello VM. Applications of nanoparticles in biology. Adv Mater. 2008;20(22):4225-4241.
6. Pankhurst QA, Connolly J, Jones SK, Dobson J. Applications of magnetic nanoparticles in biomedicine. J Phys D Appl Phys. 2003;36(13): R167-R181.
7. Mahapatro A, Singh DK. Biodegradable nanoparticles are excellent vehicle for site directed in-vivo delivery of drugs and vaccines. J Nanobiotechnology. 2011;9(1):55.
8. Pankhurst QA, Thanh NKT, Jones SK, Dobson J. Progress in applications of magnetic nanoparticles in biomedicine. J Phys D Appl Phys. 2009;42(22):224001.
9. Fröhlich E, Samberger C, Kueznik T, et al. Cytotoxicity of nanoparticles independent from oxidative stress. J Toxicol Sci. 2009;34(4): 363-375.
10. Lewinski N, Colvin V, Drezek R. Cytotoxicity of nanoparticles. Small. 2008;4(1):26-49.
11. Douglas KL, Piccirillo CA, Tabrizian M. Cell line-dependent internalization pathways and intracellular trafficking determine transfection efficiency of nanoparticle vectors. Eur J Pharm Biopharm. 2008;68(3): 676-687.
12. Harush-Frenkel O, Altschuler Y, Benita S. Nanoparticle-cell interactions: drug delivery implications. Crit Rev Ther Drug Carrier Syst. 2008;25(6):485-544.
13. Chavanpatil MD, Khdair A, Panyam J. Nanoparticles for cellular drug delivery: mechanisms and factors influencing delivery. J Nanosci Nanotechnol. 2006;6(9-10):2651-2663.
14. Huang X, Teng X, Chen D, Tang F, He J. The effect of the shape of mesoporous silica nanoparticles on cellular uptake and cell function. Biomaterials. 2010;31(3):438-448.
15. Chithrani BD, Ghazani AA, Chan WC. Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Lett. 2006;6(4):662-668.
16. Wilhelm C, Gazeau F, Roger J, Pons JN, Bacri JC. Interaction of anionic superparamagnetic nanoparticles with cells: kinetic analyses of membrane adsorption and subsequent internalization. Langmuir. 2002;18(21):8148-8155.
17. Chithrani BD, Chan WC. Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes. Nano Lett. 2007;7(6):1542-1550.
18. Kim JS, Yoon TJ, Yu KN, et al. Cellular uptake of magnetic nanoparticle is mediated through energy-dependent endocytosis in A549 cells. J Vet Sci. 2006;7(4):321-326.
19. Shukla R, Bansal V, Chaudhary M, Basu A, Bhonde RR, Sastry M. Biocompatibility of gold nanoparticles and their endocytotic fate inside the cellular compartment: a microscopic overview. Langmuir. 2005;21(23):10644-10654.
20. Suh H, Jeong B, Liu F, Kim SW. Cellular uptake study of biodegradable nanoparticles in vascular smooth muscle cells. Pharm Res. 1998;15(9):1495-1498.
21. Kumari S, Mg S, Mayor S. Endocytosis unplugged: multiple ways to enter the cell. Cell Res. 2010;20(3):256-275.
22. Cartiera MS, Johnson KM, Rajendran V, Caplan MJ, Saltzman WM. The uptake and intracellular fate of PLGA nanoparticles in epithelial cells. Biomaterials. 2009;30(14):2790-2798.
23. Yen HJ, Hsu SH, Tsai CL. Cytotoxicity and immunological response of gold and silver nanoparticles of different sizes. Small. 2009;5(13): 1553-1561.
24. Soenen SJ, Nuytten N, De Meyer SF, De Smedt SC, De Cuyper M. High intracellular iron oxide nanoparticle concentrations affect cellular cytoskeleton and focal adhesion kinase-mediated signaling. Small. 2010;6(7):832-842.
25. AshaRani PV, Low Kah Mun G, Hande MP, Valiyaveettil S. Cytotoxicity and genotoxicity of silver nanoparticles in human cells. ACS Nano. 2009;3(2):279-290.
26. Stayton I, Winiarz J, Shannon K, Ma Y. Study of uptake and loss of silica nanoparticles in living human lung epithelial cells at single cell level. Anal Bioanal Chem. 2009;394(6):1595-1608.
27. Besic Gyenge E, Darphin X, Wirth A, et al. Uptake and fate of surface modified silica nanoparticles in head and neck squamous cell carcinoma. J Nanobiotechnology. 2011;9:32.
28. Moore A, Weissleder R, Bogdanov A Jr. Uptake of dextran-coated monocrystalline iron oxides in tumor cells and macrophages. J Magn Reson Imaging. 1997;7(6):1140-1145.
29. Busch W, Bastian S, Trahorsch U, et al. Internalisation of engineered nanoparticles into mammalian cells in vitro: influence of cell type and particle properties. J Nanopart Res. 2011;13(1):293-310.
30. Nam HY, Kwon SM, Chung H, et al. Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles. J Control Release. 2009;135(3):259-267.
31. Yan Y, Johnston AP, Dodds SJ, et al. Uptake and intracellular fate of disulfide-bonded polymer hydrogel capsules for Doxorubicin delivery to colorectal cancer cells. ACS Nano. 2010;4(5):2928-2936.
32. Marmorato P, Ceccone G, Gianoncelli A, et al. Cellular distribution and degradation of cobalt ferrite nanoparticles in Balb/3T3 mouse fibroblasts. Toxicol Lett. 2011;207(2):128-136.
33. Xiao Y, Forry SP, Gao X, Holbrook RD, Telford WG, Tona A. Dynamics and mechanisms of quantum dot nanoparticle cellular uptake. J Nanobiotechnology. 2010;8:13.
34. Qi LF, Xu ZR, Li Y, Jiang X, Han XY. In vitro effects of chitosan nanoparticles on proliferation of human gastric carcinoma cell line MGC803 cells. World J Gastroenterol. 2005;11(33):5136-5141.
35. Berry CC, Wells S, Charles S, Aitchison G, Curtis AS. Cell response to dextran-derivatised iron oxide nanoparticles post internalisation. Biomaterials. 2004;25(23):5405-5413.
36. Asharani PV, Hande MP, Valiyaveettil S. Anti-proliferative activity of silver nanoparticles. BMC Cell Biol. 2009;10:65.
37. Campelj S, Makovec D, Drofenik M. Preparation and properties of water-based magnetic fluids. J Phys Condens Matter. 2008;20(20):204101.
38. Tourinho FA, Franck R, Massart R. Aqueous ferrofluids based on manganese and cobalt ferrites. J Mater Sci. 1990;25(7):3249-3254.
39. Bregar VB, Pavlin M, Žnidaršič A. Magnetization state in magnetic nanoparticle agglomerates. Proceedings of the 8th International Conference on the Scientific and Clinical Applications of Magnetic Carriers; May 25-29, 2010; Rostock, Germany. Melville, NY: American Institute of Physics; 2010;1311(1):59-64.
40. Prijic S, Prosen L, Cemazar M, et al. Surface modified magnetic nanoparticles for immuno-gene therapy of murine mammary adenocarcinoma. Biomaterials. 2012;33(17): 4379-4391.
41. Pavlin M, Bregar VB. Stability of nanoparticle suspensions in different biologically relevant media. Dig J Nanomater Bios. 2012;7(4): 1389-1400.
42. Mercer J, Helenius A. Virus entry by macropinocytosis. Nat Cell Biol. 2009;11(5):510-520.
43. Kocbek P, Teskač K, Kreft ME, Kristl J. Toxicological aspects of long-term treatment of keratinocytes with ZnO and TiO2 nanoparticles. Small. 2010;6(17):1908-1917.
44. Roohi F, Lohrke J, Ide A, Schütz G, Dassler K. Studying the effect of particle size and coating type on the blood kinetics of superparamagnetic iron oxide nanoparticles. Int J Nanomedicine. 2012;7:4447-4458.
45. Ding D, Zhu Z, Liu Q, et al. Cisplatin-loaded gelatin-poly(acrylic acid) nanoparticles: synthesis, antitumor efficiency in vivo and penetration in tumors. Eur J Pharm Biopharm. 2011;79(1):142-149.
46. Hu Y, Ding Y, Ding D, et al. Hollow chitosan/poly(acrylic acid) nanospheres as drug carriers. Biomacromolecules. 2007;8(4):1069-1076.
47. Safi M, Sarrouj H, Sandre O, Mignet N, Berret J-F. Interactions between sub-10-nm iron and cerium oxide nanoparticles and 3T3 fibroblasts: the role of the coating and aggregation state. Nanotechnology. 2010;21(14): 145103.
48. Quintart J, Leroy-Houyet MA, Trouet A, Baudhuin P. Endocytosis and chloroquine accumulation during the cell cycle of hepatoma cells in culture. J Cell Biol. 1979;82(3):644-653.
49. Fielding AB, Willox AK, Okeke E, Royle SJ. Clathrin-mediated endocytosis is inhibited during mitosis. Proc Natl Acad Sci U S A. 2012;109(17):6572-6577.
50. Swanson JA, Watts C. Macropinocytosis. Trends Cell Biol. 1995;5(11): 424-428.
51. Verma A, Stellacci F. Effect of surface properties on nanoparticle-cell interactions. Small. 2010;6(1):12-21.
52. Di Virgilio AL, Reigosa M, Arnal PM, Fernández Lorenzo de Mele M. Comparative study of the cytotoxic and genotoxic effects of titanium oxide and aluminium oxide nanoparticles in Chinese hamster ovary (CHO-K1) cells. J Hazard Mater. 2010;177(1-3):711-718.
53. Dittrich C, Burckhardt CJ, Danuser G. Delivery of membrane impermeable cargo into CHO cells by peptide nanoparticles targeted by a protein corona. Biomaterials. 2012;33(9):2746-2753.
54. Vercauteren D, Vandenbroucke RE, Jones AT, et al. The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls. Mol Ther. 2010;18(3):561-569.
55. Ivanov AI. Pharmacological inhibition of endocytic pathways: is it specific enough to be useful? In: Ivanov AI, Walker JM, editors. Exocytosis and Endocytosis. Methods in Molecular Biology. Totowa: Humana Press; 2008;440:15-33.
56. Iversen TG, Skotland T, Sandvig K. Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies. Nano Today. 2011;6(2):176-185.
57. Luzio JP, Pryor PR, Bright NA. Lysosomes: fusion and function. Nat Rev Mol Cell Biol. 2007;8(8):622-632.
58. Panyam J, Labhasetwar V. Dynamics of endocytosis and exocytosis of poly(D, L-lactide-co-glycolide) nanoparticles in vascular smooth muscle cells. Pharm Res. 2003;20(2):212-220.