Effects of CPAP on nitrate and norepinephrine levels in severe and mild-moderate sleep apnea

BMC Pulmonary Medicine

Volumn 13, Issue 1, 2013, Pages

  Pinto, Paula ^a,b,c   Bárbara, Cristina ^a,b,c   Montserrat, Joseph M ^d   Patarrão, Rita S ^b   Guarino, Maria P ^b   Carmo, Miguel M ^b   Macedo, Maria P ^b   Martinho, Cristina ^a   Dias, Rita ^a   Gomes, Maria J M ^b,c  

^a HOSPITAL PULIDO VALENTE   (Portugal)

^b NOVA MEDICAL SCHOOL   (Portugal)

^c Nona Medical School   (Portugal)

^d INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

NITRATE; NORADRENALIN;

ADULT; ARTICLE; BLOOD LEVEL; BLOOD PRESSURE; CONTROLLED STUDY; HUMAN; MAJOR CLINICAL STUDY; MALE; MILD MODERATE OBSTRUCTIVE SLEEP APNEA; NITRATE BLOOD LEVEL; NORADRENALIN URINE LEVEL; POSITIVE END EXPIRATORY PRESSURE; PROSPECTIVE STUDY; SEVERE OBSTRUCTIVE SLEEP APNEA; SLEEP DISORDERED BREATHING; TREATMENT RESPONSE;

ADULT; BIOLOGICAL MARKERS; BLOOD PRESSURE MONITORING, AMBULATORY; CONTINUOUS POSITIVE AIRWAY PRESSURE; HUMANS; MALE; MIDDLE AGED; NITRATES; NOREPINEPHRINE; OXYGEN; POLYSOMNOGRAPHY; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; SLEEP APNEA SYNDROMES; TREATMENT OUTCOME;

EID: 84874806261     PISSN: None     EISSN: 14712466     Source Type: Journal    
DOI: 10.1186/1471-2466-13-13     Document Type: Article

References (34)

1. Shahar E, Whitney CW, Redline S, Lee ET, Newman AB, Nieto FJ, O'connor GT, Boland LL, Schwartz JE, Samet JM. Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study. Am J Respir Crit Care Med 2001, 163:19-25.
2. Peppard PE, Young T, Palta M, Skatrud J. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med 2000, 342:1378-1384. 10.1056/NEJM200005113421901, 10805822.
3. Nieto FJ, Young TB, Lind BK, Shahar E, Samet JM, Redline S, D'Agostino RB, Newman AB, Lebowitz MD, Pickering TG, . for the Sleep Heart Health Study Association of sleep-disordered breathing, sleep apnea and hypertension in a large community-based study. JAMA 2000, 283:1829-1836. 10.1001/jama.283.14.1829, 10770144, for the Sleep Heart Health Study.
4. McNicholas WT, Bonsignore MR, . and the Management Committee of EU COST ACTION B26 Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities. Eur Respir J 2007, 29:156-178. and the Management Committee of EU COST ACTION B26.
5. Bradley TD, Floras JS. Obstructive sleep apnea and its cardiovascular consequences. Lancet 2009, 373:82-93. 10.1016/S0140-6736(08)61622-0, 19101028.
6. Loube DI, Gay PC, Strohl KP, Pack AI, White DP, Collop NA. Indications for positive airway pressure treatment of adult obstructive sleep apnea patients. Chest 1999, 115:863-866. 10.1378/chest.115.3.863, 10084504.
7. Kushida CA, Littner MR, Hirshkowitz M. Practice parameters for the use of continuous and bilevel positive airway pressure devices to treat adult patients with sleep-related breathing disorders. Sleep 2006, 29:375-380.
8. Buchner NJ, Sanner BM, Borgel J, Rump LC. CPAP treatment of mild to moderate obstructive sleep apnea reduces cardiovascular risk. Am J Respir Crit Care Med 2007, 176:1274-1280. 10.1164/rccm.200611-1588OC, 17673692.
9. Ip MSM, Lam B, Chan L, Zheng L, Tsang KWT, Fng PCW, Lam W. Circulating nitric oxide is suppressed in obstructive sleep apnea and is reversed by nasal continuous positive airway pressure. Am J Respir Crit Care Med 2000, 162:2166-2171.
10. Schulz R, Schmidt D, Blum A, Lopes-Ribeiro X, Lucke C, Mayer K, Olschewski H, Seeger W, Grimminger F. Decreased plasma levels of nitric oxide derivatives in obstructive sleep apnoea: response to CPAP therapy. Thorax 2000, 55:1046-1051. 10.1136/thorax.55.12.1046, 1745665, 11083891.
11. Lavie L, Hefetz A, Luboshitzky R, Lavie P. Plasma levels of nitric oxide and L-arginine in sleep apnea patients. Effects of nCPAP treatment. J Mol Neurosci 2003, 21:57-63. 10.1385/JMN:21:1:57, 14500996.
12. Alonso-Fernández A, Garcia-Rio F, Arias MA, Hernanz A, Peña M, Pierola J, Barceló A, López-Collazo E, Garcia AA. Effects of CPAP upon oxidative stress and nitrate efficiency in sleep apnoea. A randomized trial. Thorax 2009, 64:581-586.
13. Sukegawa M, Noda A, Sugiura T, Nakata S, Yoshizaki S, Soga T, Yasuda Y, Iwayama N, Nakai S, Koike Y. Assessment of continuous positive airway pressure treatment in obstructive sleep apnea syndrome using 24-hour urinary catecholamines. Clin Cardiol 2005, 28:519-522. 10.1002/clc.4960281106, 16450795.
14. Elmasry A, Lindberg E, Hedner J, Janson C, Boman G. Obstructive sleep anoea and urine catecholamines in hypertensive males: a population-based study. Eur Respir J 2002, 19:511-517. 10.1183/09031936.02.00106402, 11936531.
15. Hedner J, Darpo B, Ejnell H, Carlson J, Caidahl K. Reduction in sympathetic activity after long-term CPAP treatment in sleep apnoea: cardiovascular implications. Eur Respir J 1995, 8:222-229. 10.1183/09031936.95.08020222, 7758555.
16. Marrone O, Riccobono L, Salvaggio A, Mirabella A, Bonanno A, Bonsignore MR. Catecholamines and blood pressure in obstructive sleep apnea syndrome. Chest 1993, 103:722-727. 10.1378/chest.103.3.722, 8449058.
17. Ziegler MG, Mills PJ, Loredo JS, Ancoli-Israel S, Dimsdale JE. Effect of continuous positive airway pressure and placebo treatment on sympathetic nervous activity in patients with obstructive sleep apnea. Chest 2001, 120:887-893. 10.1378/chest.120.3.887, 11555525.
18. Wang J, Brown MA, Tam SH, Chan MC, Whitworth JA. Effects of diet on measurement of nitric oxide metabolites. Clinical and Experimental Pharmacology and Physiology 1997, 24:418-420. 10.1111/j.1440-1681.1997.tb01212.x, 9171946.
19. Rechtschaffen A, Kales A. A manual of standardized terminology, techniques and scoring system for sleep stages of human subjects 1968, Education and Welfare Public Health Service - NIH/NIND: US Department of Health.
20. Iber CI, Ancoli-Israel S, Chesson L, Quan S. for the American Academy of Sleep Medicine 2007, Rules, terminology and technical specifications: The AASM Manual for the Scoring of Sleep and Associated Events.
21. Mancia G, Backer G, Dominiczack A, Cifkova R, Fagard R, Germano G, Grassi G, Heagerty A, Kjeldsen S, Laurent S, Narkiewicz K, Ruilope L, Rynkiewicz A, Schmieder R, Boudier H, Zanchetti A. Guidelines for the management of arterial hypertension. The task force for the management of arterial hypertension of the European Society of Hypertension (ESH) ad of the European Society of Cardiology (ESC). Journal of Hypertension 2007, 25:1105-1187. 10.1097/HJH.0b013e3281fc975a, 17563527.
22. Yang F, Troncy E, Francoeur M, Vinet B, Vinay P, Czaika G, Blaise G. Effects of reducing reagents and temperature on conversion of nitrite and nitrate to nitric oxide and detection of NO by chemiluminescence. Clin Chem 1997, 43:657-662.
23. Cox RD, Frank CW. Determination of nitrate and nitrite in blood and urine by chemiluminescence. J Anal Toxicol 1982, 6:148-152.
24. Braman RS, Hendrix SA. Nanogram nitrite and nitrate determination in environmental and biological materials by vanadium (III) reduction with chemiluminescence detection. Anal Chem 1989, 61:2715-2718. 10.1021/ac00199a007, 2619057.
25. Macdonald IA, Lake DM. An improved technique for extracting catecholamines from body fluids. J Eurosci Meth 1985, 13:239-248.
26. Laederach K, Weidmann P. Pasma and urinary catecholamines as related to renal function in man. Kidney Inc 1987, 31:107-111.
27. McQuillan LP, Leung GK, Marsden PA. Hypoxia inhibits expression of eNOS via transcriptional and post-transcriptional mechanisms. Am J Physiol 1994, 267:1921-1927.
28. Carlson J, Hedner J, Pettersson A. Increased plasma concentration of ADMA, a naturally occurring nitric oxde synthesis inhibitor in OSA patients. Am J Respir Crit Care Med 1997, 155:A869.
29. Schulz R, Mahmoudi S, Hattar K. Enhanced release of superoxide from polymorphonuclear neutrophils in obstructive sleep apnea: impact of CPAP therapy. Am J Respir Crit Care Med 2000, 162:566-570.
30. Martinez-Garcia MA, Gómez-Aldaravi R, Soler-Cataluna JJ, Martinez TG, Bernácer-Alpera B, Román-Sánchez P. Positive effect of CPAP treatment on the control of difficult-to-treat hypertension. Eur Respir J 2007, 29:951-957. 10.1183/09031936.00048606, 17301092.
31. Pepperell JC, Ramdassing-Dow S, Crosthwaite N, Mllins R, Jenkinson C, Stradling JR, Davies RJO. Ambulatory blood pressure after therapeutic and subtherapeutic nasal continuous positive airway pressure for obstructive sleep apnoea: a randomised parallel trial. Lancet 2002, 359:204-210. 10.1016/S0140-6736(02)07445-7, 11812555.
32. Faccenda JF, Mackay TW, Boon NA, Douglas NJ. Randomized placebo-controlled trial of continuous positive airway pressure on blood pressure in the sleep apnea-hypopnea syndrome. Am J Respir Crit Care Med 2001, 163:344-348.
33. Haentjens P, Van Meerhaeghe A, Moscariello A, Weerdt S, Poppe K, Dupont A, Velkeniers B. The impact of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea syndrome. Evidence from a meta-analysis of plaebo-controlled randomized trials. Arch Intern Med 2007, 167:757-765. 10.1001/archinte.167.8.757, 17452537.
34. Young T, Finn L, Peppard PE, Szklo-Coxe M, Austin D, Nieto J, Stubb R, Hla KM. Sleep disordered breathing and mortality: eighteen-year follow-up of the Wisconsin Sleep Cohort. Sleep 2008, 31:1071-1078. 2542952, 18714778.