STAT3 is involved in esophageal carcinogenesis through regulation of Oct-1

Carcinogenesis

Volumn 34, Issue 3, 2013, Pages 678-688

  Wang, Zhipeng ^a   Zhu, Shaojun ^b   Shen, Min ^c   Liu, Juanjuan ^a   Wang, Meng ^a   Li, Chen ^a   Wang, Yukun ^a   Deng, Anmei ^d   Mei, Qibing ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^d SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; OCTAMER TRANSCRIPTION FACTOR 1; PROTEIN KINASE B; STAT3 PROTEIN;

ARTICLE; CANCER INVASION; CARCINOGENESIS; CELL MIGRATION; ENZYME ACTIVATION; EPITHELIUM CELL; ESOPHAGEAL EPITHELIUM CELL; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANIMALS; APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; ESOPHAGEAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED BALB C; MICE, NUDE; MIDDLE AGED; NEOPLASM TRANSPLANTATION; ORGANIC CATION TRANSPORTER 1; PROMOTER REGIONS, GENETIC; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTIONAL ACTIVATION; TUMOR BURDEN;

EID: 84874789333     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgs361     Document Type: Article

References (29)

1. Zhang, Y. et al. (2012) Reciprocal activation between PLK1 and Stat3 contributes to survival and proliferation of esophageal cancer cells. Gastroenterology, 142, 521-530.e3.
2. Hemmann, U. et al. (1996) Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation. J. Biol. Chem., 271, 12999-13007.
3. Kusaba, T. et al. (2006) Activation of STAT3 is a marker of poor prognosis in human colorectal cancer. Oncol. Rep., 15, 1445-1451.
4. Burke, W.M. et al. (2001) Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells. Oncogene, 20, 7925-7934.
5. Aziz, M.H. et al. (2010) Protein kinase Cvarepsilon mediates Stat3Ser727 phosphorylation, Stat3-regulated gene expression, and cell invasion in various human cancer cell lines through integration with MAPK cascade (RAF-1, MEK1/2, and ERK1/2). Oncogene, 29, 3100-3109.
6. Couto, J.P. et al. (2012) STAT3 negatively regulates thyroid tumorigenesis. Proc. Natl. Acad. Sci. U.S.A., 109, E2361-E2370.
7. Yan, S. et al. (2008) beta-Catenin/TCF pathway upregulates STAT3 expression in human esophageal squamous cell carcinoma. Cancer Lett., 271, 85-97.
8. Lee, M.C. et al. (2010) Drosophila octamer elements and Pdm-1 dictate the coordinated transcription of core histone genes. J. Biol. Chem., 285, 9041-9053.
9. Wang, P. et al. (2009) POU homeodomain protein Oct-1 functions as a sensor for cyclic AMP. J. Biol. Chem., 284, 26456-26465.
10. Obinata, D. et al. (2012) Oct1 regulates cell growth of LNCaP cells and is a prognostic factor for prostate cancer. Int. J. Cancer, 130, 1021-1028.
11. Wang, Z. et al. (2009) Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression. Exp. Mol. Med., 41, 717-727.
12. Dong, L. et al. (2011) Ets-1 mediates upregulation of Mcl-1 downstream of XBP-1 in human melanoma cells upon ER stress. Oncogene, 30, 3716-3726.
13. Tian, Y. et al. (2011) Tumor suppressor RASSF1A promoter: p53 binding and methylation. PLoS ONE, 6, e17017.
14. Wang, F. et al. (2011) Identification of RegIV as a novel GLI1 target gene in human pancreatic cancer. PLoS ONE, 6, e18434.
15. Dufour, A. et al. (2011) Small-molecule anticancer compounds selectively target the hemopexin domain of matrix metalloproteinase-9. Cancer Res., 71, 4977-4988.
16. Angus, SP. et al. (2012) A role for Mediator complex subunit MED13L in Rb/E2F-induced growth arrest. Oncogene, 31(44): 4709-4717.
17. Zaborowska, J. et al. (2012) A novel TBP-TAF complex on RNA polymerase II-transcribed snRNA genes. Transcription, 3, 92-104.
18. Rauch, T.A. et al. (2012) DNA methylation biomarkers for lung cancer. Tumour Biol., 33, 287-296.
19. Ge, R. et al. (2011) F-box protein 10, an NF-κB-dependent anti-apoptotic protein, regulates TRAIL-induced apoptosis through modulating c-Fos/c-FLIP pathway. Cell Death Differ., 18, 1184-1195.
20. Bowman, T. et al. (2000) STATs in oncogenesis. Oncogene, 19, 2474-2488.
21. Song, J.I. et al. (2000) STAT signaling in head and neck cancer. Oncogene, 19, 2489-2495.
22. Xiong, H. et al. (2008) Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells. Neoplasia, 10, 287-297.
23. Okamoto, W. et al. (2011) Differential roles of STAT3 depending on the mechanism of STAT3 activation in gastric cancer cells. Br. J. Cancer, 105, 407-412.
24. Yakata, Y. et al. (2007) Expression of p-STAT3 in human gastric carcinoma: significant correlation in tumour invasion and prognosis. Int. J. Oncol., 30, 437-442.
25. Yadav, A. et al. (2011) IL-6 promotes head and neck tumor metastasis by inducing epithelial-mesenchymal transition via the JAK-STAT3-SNAIL signaling pathway. Mol. Cancer Res., 9, 1658-1667.
26. Zhou, C. et al. (2008) Oct-1 induces pituitary tumor transforming gene expression in endocrine tumors. Endocr. Relat. Cancer, 15, 817-831.
27. Liao, YC. et al. (2011) Overexpressed hPTTG1 promotes breast cancer cell invasion and metastasis by regulating GEF-H1/RhoA signalling. Oncogene, 31(25): 3086-3097.
28. Vince, J.E. et al. (2010) IRF-3 partners Bax in a viral-induced dance macabre. EMBO J., 29, 1627-1628.
29. Shah, M. et al. (2012) An MMP13-selective inhibitor delays primary tumor growth and the onset of tumor-associated osteolytic lesions in experimental models of breast cancer. PLoS ONE, 7, e29615.