Overexpressed C-type natriuretic peptide serves as an early compensatory response to counteract extracellular matrix remodeling in unilateral ureteral obstruction rats

Molecular Biology Reports

Volumn 40, Issue 2, 2013, Pages 1429-1441

  Hu, Peng ^a   Wang, Jing ^a   Zhao, Xue Qi ^a   Hu, Bo ^a   Lu, Ling ^a   Qin, Yuan Han ^b  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY   (China)

Author keywords

C type natriuretic peptide; Epithelial mesenchymal transdifferentiation; Extracellular matrix; Matrix metalloproteinases; Tubulointerstitial fibrosis; Wistar rat

Indexed keywords

COLLAGEN TYPE 4; GELATINASE A; GELATINASE B; MESSENGER RNA; NATRIURETIC PEPTIDE TYPE C; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE OVEREXPRESSION; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; TISSUE REACTION; URETER OBSTRUCTION; WESTERN BLOTTING;

ANIMALS; COLLAGEN TYPE IV; EPITHELIAL-MESENCHYMAL TRANSITION; EXTRACELLULAR MATRIX; FIBROSIS; GENE EXPRESSION; KIDNEY; KIDNEY DISEASES; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NATRIURETIC PEPTIDE, C-TYPE; ORGAN SIZE; RATS; RATS, WISTAR; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2; URETERAL OBSTRUCTION;

RATTUS; RATTUS NORVEGICUS;

EID: 84874788948     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-012-2186-7     Document Type: Article

References (52)

1. Nangaku M (2006) Chronic hypoxia and tubulointerstitial injury: a final common pathway to end-stage renal failure. J Am Soc Nephrol 17:17-25
2. Hewitson TD (2009) Renal tubulointerstitial fibrosis: common but never simple. Am J Physiol Renal Physiol 296:F1239-F1244
3. De Heer E, Sijpkens YW, Verkade M, den Dulk M, Langers A, Schutrups J, Bruijn JA, van Es LA (2000) Morphometry of interstitial fibrosis. Nephrol Dial Transplant 15:72-73
4. Catania JM, Chen G, Parrish AR (2007) Role of matrix metalloproteinases in renal pathophysiologies. Am J Physiol Renal Physiol 292:F905-F911
5. Duymelinck C, Dauwe SE, De Greef KE, Ysebaert DK, Verpooten GA, De Broe ME (2000) TIMP-1 gene expression and PAI-1 antigen after unilateral ureteral obstruction in the adult male rat. Kidney Int 58:1186-1201
6. Cheng S, Pollock AS, Mahimkar R, Olson JL, Lovett DH (2006) Matrix metalloproteinase 2 and basement membrane integrity: a unifying mechanism for progressive renal injury. FASEB J 20:1898-1900
7. Baxter GF (2004) The natriuretic peptides. Basic Res Cardiol 99:71-75
8. Cataliotti A, Giordano M, De Pascale E, Giordano G, Castellino P, Jougasaki M, Costello LC, Boerrigter G, Tsuruda T, Belluardo P, Lee SC, Huntley B, Sandberg S, Malatino LS, Burnett JC Jr (2002) CNP production in the kidney and effects of protein intake restriction in nephrotic syndrome. Am J Physiol Renal Physiol 283:F464-F472
9. Dean AD, Vehaskari VM, Greenwald JE (1994) Synthesis and localization of C-type natriuretic peptide in mammalian kidney. Am J Physiol 266:F491-F496
10. Mattingly MT, Brandt RR, Heublein DM, Wei CM, Nir A, Burnett JC Jr (1994) Presence of C-type natriuretic peptide in human kidney and urine. Kidney Int 46:744-747
11. Sangaralingham SJ, Heublein DM, Grande JP, Cataliotti A, Rule AD, McKie PM, Martin FL, Burnett JC Jr (2011) Urinary C-type natriuretic peptide excretion: a potential novel biomarker for renal fibrosis during aging. Am J Physiol Renal Physiol 301:F943-F952
12. Hu P, Lu L, Hu B, Qin YH (2010) Renal action of C-type natriuretic peptide: advocating the isolated perfused rat kidney model. Saudi J Kidney Dis Transpl 21:613-620
13. Ahluwalia A, MacAllister RJ, Hobbs AJ (2004) Vascular actions of natriuretic peptides. Cyclic GMP-dependent and -independent mechanisms. Basic Res Cardiol 99:83-89
14. Del Ry S, Giannessi D, Maltinti M, Prontera C, Iervasi A, Colotti C, Emdin M, L'Abbate A, Neglia D (2007) Increased levels of C-type natriuretic peptide in patients with idiopathic left ventricular dysfunction. Peptides 28:1068-1073
15. Palmer SC, Prickett TC, Espiner EA, Yandle TG, Richards AM (2009) Regional release and clearance of C-type natriuretic peptides in the human circulation and relation to cardiac function. Hypertension 54:612-618
16. Sangaralingham SJ, Huntley BK, Martin FL, McKie PM, Bellavia D, Ichiki T, Harders GE, Chen HH, Burnett JC Jr (2011) The aging heart, myocardial fibrosis, and its relationship to circulating C-type natriuretic Peptide. Hypertension 57:201-207
17. Canaan-Kühl S, Ostendorf T, Zander K, Koch KM, Floege J (1998) C-type natriuretic peptide inhibits mesangial cell proliferation and matrix accumulation in vivo. Kidney Int 53:1143-1151
18. Segawa K, Minami K, Jimi N, Nakashima Y, Shigematsu A (1998) C-type natriuretic peptide inhibits rat mesangial cell proliferation by a phosphorylation-dependent mechanism. Naunyn Schmiedebergs Arch Pharmacol 357:70-76
19. Park HC, Yasuda K, Ratliff B, Stoessel A, Sharkovska Y, Yamamoto I, Jasmin JF, Bachmann S, Lisanti MP, Chander P, Goligorsky MS (2010) Postobstructive regeneration of kidney is derailed when surge in renal stem cells during course of unilateral ureteral obstruction is halted. Am J Physiol Renal Physiol 298:F357-F364
20. Schmittgen TD, Livak KJ (2008) Analyzing real-time PCR data by the comparative C(T) method. Nat Protoc 3:1101-1108
21. Oldroyd SD, Thomas GL, Gabbiani G, El Nahas AM (1999) Interferon-gamma inhibits experimental renal fibrosis. Kidney Int 56:2116-2127
22. Vaillancourt P, Omer S, Palfree R, Varma DR, Mulay S (1997) Downregulation of adrenal atrial natriuretic peptide receptor mRNAs and proteins by pregnancy in rats. J Endocrinol 155:523-530
23. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
24. Zhou TB, Qin YH, Li ZY, Xu HL, Zhao YJ, Lei FY (2012) All-trans retinoic acid treatment is associated with prohibitin expression in renal interstitial fibrosis rats. Int J Mol Sci 13:2769-2782
25. Buerkert J, Martin D, Head M, Prasad J, Klahr S (1978) Deep nephron function after release of acute unilateral ureteral obstruction in the young rat. J Clin Invest 62:1228-1239
26. Chevalier RL, Thornhill BA, Chang AY (2000) Unilateral ureteral obstruction in neonatal rats leads to renal insufficiency in adulthood. Kidney Int 58:1987-1995
27. Nangaku M (2004) Mechanisms of tubulointerstitial injury in the kidney: final common pathways to end-stage renal failure. Intern Med 43:9-17
28. Ardissino G, Testa S, Daccò V, Viganò S, Taioli E, Claris-Appiani A, Procaccio M, Avolio L, Ciofani A, Dello Strologo L, Montini G, Ital Kid Project (2004) Proteinuria as a predictor of disease progression in children with hypodysplastic nephropathy. Data from the Ital Kid Project. Pediatr Nephrol 19:172-177
29. Hu P, Lu L, Hu B, Du PF (2009) Characteristics of lipid metabolism under different urinary protein excretion in children with primary nephrotic syndrome. Scand J Clin Lab Invest 69:680-686
30. Nangaku M, Eckardt KU (2007) Hypoxia and the HIF system in kidney disease. J Mol Med 85:1325-1330
31. Nangaku M, Inagi R, Miyata T, Fujita T (2007) Angiotensin-induced hypoxia in the kidney: functional and structural changes of the renal circulation. Adv Exp Med Biol 618:85-99
32. Mimura I, Nangaku M (2010) The suffocating kidney: tubulointerstitial hypoxia in end-stage renal disease. Nat Rev Nephrol 6:667-678
33. De Laplanche E, Gouget K, Cléris G, Dragounoff F, Demont J, Morales A, Bezin L, Godinot C, Perrière G, Mouchiroud D, Simonnet H (2006) Physiological oxygenation status is required for fully differentiated phenotype in kidney cortex proximal tubules. Am J Physiol Renal Physiol 291:F750-F760
34. Erkan E, Devarajan P, Schwartz GJ (2007) Mitochondria are the major targets in albumin-induced apoptosis in proximal tubule cells. J Am Soc Nephrol 18:1199-1208
35. Tanaka T, Hanafusa N, Ingelfinger JR, Ohse T, Fujita T, Nangaku M (2003) Hypoxia induces apoptosis in SV40-immortalized rat proximal tubular cells through the mitochondrial pathways, devoid of HIF1-mediated upregulation of Bax. Biochem Biophys Res Commun 309:222-231
36. Chevalier RL, Kim A, Thornhill BA, Wolstenholme JT (1999) Recovery following relief of unilateral ureteral obstruction in the neonatal rat. Kidney Int 55:793-807
37. Jones CL (1996) Matrix degradation in renal disease. Nephrology (Carlton) 2:13-23
38. Lelongt B, Trugnan G, Murphy G, Ronco PM (1997) Matrix metalloproteinases MMP2 and MMP9 are produced in early stages of kidney morphogenesis but only MMP9 is required for renal organogenesis in vitro. J Cell Biol 136:1363-1373
39. Li MX, Liu BC (2007) Epithelial to mesenchymal transition in the progression of tubulointerstitial fibrosis. Chin Med J (Engl) 120:1925-1930
40. Toth M, Chvyrkova I, Bernardo MM, Hernandez-Barrantes S, Fridman R (2003) Pro-MMP-9 activation by the MT1-MMP/MMP-2 axis and MMP-3: role of TIMP-2 and plasma membranes. Biochem Biophys Res Commun 308:386-395
41. Alcaraz LA, Banci L, Bertini I, Cantini F, Donaire A, Gonnelli L (2007) Matrix metalloproteinase-inhibitor interaction: the solution structure of the catalytic domain of human matrix metalloproteinase-3 with different inhibitors. J Biol Inorg Chem 12:1197-1206
42. Hu P, Qin YH, Pei J, Lei FY, Hu B, Lu L (2010) Beneficial effect of all-trans retinoic acid (ATRA) on glomerulosclerosis rats via the down-regulation of the expression of alpha-smooth muscle actin: a comparative study between ATRA and benazepril. Exp Mol Pathol 89:51-57
43. Qin YH, Lei FY, Hu P, Pei J, Feng ZB, Pang YS (2009) Effect of all-trans retinoic acid on renal expressions of matrix metalloproteinase-2, matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in rats with glomerulosclerosis. Pediatr Nephrol 24:1477-1486
44. Qin YH, Zhou TB, Lei FY, Huang WF, Zhao YJ, Lin FQ, Su LN (2011) Cut-off values for serum matrix metalloproteinase-9: is there a threshold to predict renal involvement for Henoch-Schonlein purpura in children? Nephrology (Carlton) 16:93-99
45. Hussein Ahmed AK (2009) Matrix metalloproteinases and their inhibitors in kidney scarring: culprits or innocents. J Health Sci 55:473-483
46. Johnson TS, Haylor JL, Thomas GL, Fisher M, El Nahas AM (2002) Matrix metalloproteinases and their inhibitions in experimental renal scarring. Exp Nephrol 10:182-195
47. Kim H, Oda T, Lopez-Guisa J, Wing D, Edwards DR, Soloway PD, Eddy AA (2001) TIMP-1 deficiency does not attenuate interstitial fibrosis in obstructive nephropathy. J Am Soc Nephrol 12:736-748
48. Igaki T, Itoh H, Suga S, Hama N, Ogawa Y, Komatsu Y, Mukoyama M, Sugawara A, Yoshimasa T, Tanaka I, Nakao K (1996) C-type natriuretic peptide in chronic renal failure and its action in humans. Kidney Int Suppl 55:S144-S147
49. Das S, Au E, Krazit ST, Pandey KN (2010) Targeted disruption of guanylyl cyclase-A/natriuretic peptide receptor-A gene provokes renal fibrosis and remodeling in null mutant mice: role of proinflammatory cytokines. Endocrinology 151:5841-5850
50. Hu P, Wang J, Hu B, Lu L, Xuan Q, Qin YH (2012) Increased urinary C-type natriuretic peptide excretion may be an early marker of renal tubulointerstitial fibrosis. Peptides 37:98-105
51. Doi K, Ikeda T, Itoh H, Ueyama K, Hosoda K, Ogawa Y, Yamashita J, Chun TH, Inoue M, Masatsugu K, Sawada N, Fukunaga Y, Saito T, Sone M, Yamahara K, Kook H, Komeda M, Ueda M, Nakao K (2001) C-type natriuretic peptide induces redifferentiation of vascular smooth muscle cells with accelerated reendothelialization. Arterioscler Thromb Vasc Biol 21:930-936
52. Woodard GE, Rosado JA, Brown J (2002) Expression and control of C-type natriuretic peptide in rat vascular smooth muscle cells. Am J Physiol Regul Integr Comp Physiol 282:R156-R165