Hypoglycemic effect of a compound herbal formulation (Ziabeen) on blood glucose in normal and alloxan-diabetic rabbits

Diabetologia Croatica

Volumn 41, Issue 3, 2012, Pages 87-94

  Akhtar, Muhammad S ^a   Zafar, Mamoona ^a   Irfan, Hafiz M ^a   Bashir, Sajid ^a  

^a UNIVERSITY OF SARGODHA   (Pakistan)

Author keywords

Alloxan; Compound herbal preparation; Diabetes; Hypoglycemic effect; Ziabeen

Indexed keywords

ALLOXAN; GLUCOSE; HERBACEOUS AGENT; INSULIN; ORAL ANTIDIABETIC AGENT; PIOGLITAZONE; UNCLASSIFIED DRUG; ZIABEEN;

ALLOXAN DIABETES MELLITUS; ALOE; ALOE BARBADENSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIABETIC ACTIVITY; ARTICLE; AZADIRACHTA INDICA; BLACK PEPPER; BODY WEIGHT; CHIRATA; CONTROLLED STUDY; DISEASE MODEL; DOSE TIME EFFECT RELATION; DRUG MEGADOSE; DRUG POTENTIATION; GLUCOSE BLOOD LEVEL; GYMNEMA SYLVESTRE; HOLARRHENA; HOLARRHENA ANTIDYSENTERICA; MOMORDICA CHARANTIA; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; REPEATED DRUG DOSE; SWERTIA; SYZYGIUM CUMINI; TOXICITY TESTING; TREATMENT DURATION; WEIGHT CONTROL;

EID: 84874744075     PISSN: 03510042     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. International Diabetic Federation Atlas 2006 showing prevalence of diabetes in 2007 and future projection for 2025. Updated 2009.
2. Davis SN. Management of type 2 diabetes mellitus with basal prandial insulin therapy: a case based review. Insulin 2007;2:118-126.
3. Said M. Hamdard pharmacopoeia of Eastern medicine. Karachi: Hamdard National Foundation Times Press, 1969;379.
4. Sabu MC, Kuttan R. Antidiabetic activities of medicinal plants and its relationship with their antioxidant properties. J Ethnopharmacol 2002;81(2):155-160.
5. Sharma VK, Kumar S, Patel HJ, Hugar S. Hypoglycaemic activity of Ficus glomerata in alloxan-induced diabetic rats. Int J Pharm Sci Rev Res 2010;1(2):18-22.
6. Akhtar MS, Akhtar MA, Yaqub M. Effect of Momordica charantia on glucose levels of normal and alloxan-diabetic rabbits. Planta Med 1981;42:205-212.
7. Khosla P, Bhanwra S, Singh J, Seth S, Srivastava RK. A study of hypoglycaemic effects of Azadirachta indica (Neem) in normal and alloxan diabetic rabbits. Indian J Physiol Pharmacol 2000;44(1):69-74.
8. Szkudelski T. The mechanism of alloxan and streptozotocin action B cells of rat pancreas. Physiol Res 2001;50:537-546.
9. Wadood N, Nisar M, Rashid A, Wadood A, Nawab G, Khan N. Effect of a compound recipe (medicinal plants) on serum levels of alloxaninduced diabetic rabbits. J Ayub Med 2007;19(1):32-38.
10. Gumieniczek A. Modification of oxidative stress by pioglitazone in the heart of alloxan-induced diabetic rabbits. J Biomed Sci 2005;12(3):531-537.
11. Habibuddin M, Daghriri HA, Humaira T, Al-Qahtani MS, Hefzi AH. Antidiabetic effect of alcoholic extract of Caralluma sinaica L. on streptozotocin-induced diabetic rabbits. J Ethnopharmacol 2008;117:215-220.
12. Laurence DR, Bacharach AL. Evaluation of drug activities: pharmacometrics, Vol. 1. London, New York: Academic Press, 1964;33-37.
13. Steel RGD, Torrie JH. Principles and procedure of statistics. New York: McGraw Hill Book Company, Inc., 1992.
14. Akhtar MS, Ramzan A, Ali A, Ahmad M. Effect of Amla fruit (Emblica officinalis - Gaertn.) on blood glucose and lipid profile of normal subjects and type 2 diabetic patients. Int J Food Sci Nutr 2011;62(6):609-616.
15. Akhtar MS, Ali MR. Study of antidiabetic effect of a compound medicinal plant prescription in normal and alloxan diabetic rabbits. J Pak Med Assoc 1984;34(8):239-244.
16. Ahmad M, Alamgeer, Sharif T. A potential adjunct of insulin Berberis lycium Royle. Diabetol Croat 2009;38(1):13-18.
17. Alarcon-Aguilar FJ, Banderas-Dorantes T, Gutierrez-Leon A, Vazquez-Carrillo L, Flores-Saenz JL, Roman-Ramos RR. Study of antihyperglycemic effect of antidiabetic plants in rabbits with impaired glucose tolerance. Proc West Pharmacol Soc 2003;46:148-152.
18. Akhtar MS, Khan S, Bashir S, Salman M. Effect of Lodoicea sechallarum, Labill (sea-coconut) fruit on blood glucose and lipid profile in type 2 diabetic and normal human volunteers. Diabetol Croat 2009;38(4):87-93.