-
1
-
-
78651529396
-
False negative rates in Drosophila cell-based RNAi screens: a case study
-
Booker, M., Samsonova, A. A., Kwon, Y., Flockhart, I., Mohr, S. E. and Perrimon, N. (2011). False negative rates in Drosophila cell-based RNAi screens: a case study. BMC Genomics 12, 50.
-
(2011)
BMC Genomics
, vol.12
, pp. 50
-
-
Booker, M.1
Samsonova, A.A.2
Kwon, Y.3
Flockhart, I.4
Mohr, S.E.5
Perrimon, N.6
-
2
-
-
61349176557
-
ADP-ribosylation factor 1 controls the activation of the phosphatidylinositol 3-kinase pathway to regulate epidermal growth factor-dependent growth and migration of breast cancer cells
-
Boulay, P. L., Cotton, M., Melançon, P. and Claing, A. (2008). ADP-ribosylation factor 1 controls the activation of the phosphatidylinositol 3-kinase pathway to regulate epidermal growth factor-dependent growth and migration of breast cancer cells. J. Biol. Chem. 283, 36425-36434.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 36425-36434
-
-
Boulay, P.L.1
Cotton, M.2
Melançon, P.3
Claing, A.4
-
3
-
-
77949834455
-
A nucleator arms race: cellular control of actin assembly
-
Campellone, K. G. and Welch, M. D. (2010). A nucleator arms race: cellular control of actin assembly. Nat. Rev. Mol. Cell Biol. 11, 237-251.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 237-251
-
-
Campellone, K.G.1
Welch, M.D.2
-
4
-
-
78649452812
-
Structure and control of the actin regulatory WAVE complex
-
Chen, Z., Borek, D., Padrick, S. B., Gomez, T. S., Metlagel, Z., Ismail, A. M., Umetani, J., Billadeau, D. D., Otwinowski, Z. and Rosen, M. K. (2010). Structure and control of the actin regulatory WAVE complex. Nature 468, 533-538.
-
(2010)
Nature
, vol.468
, pp. 533-538
-
-
Chen, Z.1
Borek, D.2
Padrick, S.B.3
Gomez, T.S.4
Metlagel, Z.5
Ismail, A.M.6
Umetani, J.7
Billadeau, D.D.8
Otwinowski, Z.9
Rosen, M.K.10
-
5
-
-
34250313651
-
Active Arf6 recruits ARNO/cytohesin GEFs to the PM by binding their PH domains
-
Cohen, L. A., Honda, A., Varnai, P., Brown, F. D., Balla, T. and Donaldson, J. G. (2007). Active Arf6 recruits ARNO/cytohesin GEFs to the PM by binding their PH domains. Mol. Biol. Cell 18, 2244-2253.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 2244-2253
-
-
Cohen, L.A.1
Honda, A.2
Varnai, P.3
Brown, F.D.4
Balla, T.5
Donaldson, J.G.6
-
6
-
-
78049487235
-
A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis
-
D'Ambrosio, M. V. and Vale, R. D. (2010). A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis. J. Cell Biol. 191, 471-478.
-
(2010)
J. Cell Biol.
, vol.191
, pp. 471-478
-
-
D'Ambrosio, M.V.1
Vale, R.D.2
-
7
-
-
0027953550
-
Dominant inhibitory mutants of ARF1 block endoplasmic reticulum to Golgi transport and trigger disassembly of the Golgi apparatus
-
Dascher, C. and Balch, W. E. (1994). Dominant inhibitory mutants of ARF1 block endoplasmic reticulum to Golgi transport and trigger disassembly of the Golgi apparatus. J. Biol. Chem. 269, 1437-1448.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 1437-1448
-
-
Dascher, C.1
Balch, W.E.2
-
8
-
-
79251507630
-
Actin-based motility: WAVE regulatory complex structure reopens old SCARs
-
Davidson, A. J. and Insall, R. H. (2011). Actin-based motility: WAVE regulatory complex structure reopens old SCARs. Curr. Biol. 21, R66-R68.
-
(2011)
Curr. Biol.
, vol.21
-
-
Davidson, A.J.1
Insall, R.H.2
-
9
-
-
79957473559
-
ARF family G proteins and their regulators: roles in membrane transport, development and disease
-
Donaldson, J. G. and Jackson, C. L. (2011). ARF family G proteins and their regulators: roles in membrane transport, development and disease. Nat. Rev. Mol. Cell Biol. 12, 362-375.
-
(2011)
Nat. Rev. Mol. Cell Biol.
, vol.12
, pp. 362-375
-
-
Donaldson, J.G.1
Jackson, C.L.2
-
10
-
-
33845900934
-
The cytohesin Steppke is essential for insulin signalling in Drosophila
-
Fuss, B., Becker, T., Zinke, I. and Hoch, M. (2006). The cytohesin Steppke is essential for insulin signalling in Drosophila. Nature 444, 945-948.
-
(2006)
Nature
, vol.444
, pp. 945-948
-
-
Fuss, B.1
Becker, T.2
Zinke, I.3
Hoch, M.4
-
11
-
-
80052622871
-
Clathrin is required for Scar/Wave-mediated lamellipodium formation
-
Gautier, J. J., Lomakina, M. E., Bouslama-Oueghlani, L., Derivery, E., Beilinson, H., Faigle, W., Loew, D., Louvard, D., Echard, A., Alexandrova, A. Y. et al. (2011). Clathrin is required for Scar/Wave-mediated lamellipodium formation. J. Cell Sci. 124, 3414-3427.
-
(2011)
J. Cell Sci.
, vol.124
, pp. 3414-3427
-
-
Gautier, J.J.1
Lomakina, M.E.2
Bouslama-Oueghlani, L.3
Derivery, E.4
Beilinson, H.5
Faigle, W.6
Loew, D.7
Louvard, D.8
Echard, A.9
Alexandrova, A.Y.10
-
12
-
-
1842428821
-
Purification and architecture of the ubiquitous Wave complex
-
Gautreau, A., Ho, H. Y., Li, J., Steen, H., Gygi, S. P. and Kirschner, M. W. (2004). Purification and architecture of the ubiquitous Wave complex. Proc. Natl. Acad. Sci. USA 101, 4379-4383.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 4379-4383
-
-
Gautreau, A.1
Ho, H.Y.2
Li, J.3
Steen, H.4
Gygi, S.P.5
Kirschner, M.W.6
-
13
-
-
33845863903
-
Grü ne, I., Srivatsan, S. G., Paul, B., Kolanus, W., Quast, T., Kremmer, E., Bauer, I. and Famulok, M
-
Hafner, M., Schmitz, A., Grü ne, I., Srivatsan, S. G., Paul, B., Kolanus, W., Quast, T., Kremmer, E., Bauer, I. and Famulok, M. (2006). Inhibition of cytohesins by SecinH3 leads to hepatic insulin resistance. Nature 444, 941-944.
-
(2006)
Nature
, vol.444
, pp. 941-944
-
-
Hafner, M.1
Schmitz, A.2
-
14
-
-
0027958423
-
Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product
-
Hart, M. J., Eva, A., Zangrilli, D., Aaronson, S. A., Evans, T., Cerione, R. A. and Zheng, Y. (1994). Cellular transformation and guanine nucleotide exchange activity are catalyzed by a common domain on the dbl oncogene product. J. Biol. Chem. 269, 62-65.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 62-65
-
-
Hart, M.J.1
Eva, A.2
Zangrilli, D.3
Aaronson, S.A.4
Evans, T.5
Cerione, R.A.6
Zheng, Y.7
-
15
-
-
61849166099
-
The Salmonella effector SptP dephosphorylates host AAA+ ATPase VCP to promote development of its intracellular replicative niche
-
Humphreys, D., Hume, P. J. and Koronakis, V. (2009). The Salmonella effector SptP dephosphorylates host AAA+ ATPase VCP to promote development of its intracellular replicative niche. Cell. Host Microbe. 5, 225-233.
-
(2009)
Cell. Host Microbe.
, vol.5
, pp. 225-233
-
-
Humphreys, D.1
Hume, P.J.2
Koronakis, V.3
-
16
-
-
84857291766
-
Salmonella virulence effector SopE and Host GEF ARNO cooperate to recruit and activate WAVE to trigger bacterial invasion
-
Humphreys, D., Davidson, A., Hume, P. J. and Koronakis, V. (2012). Salmonella virulence effector SopE and Host GEF ARNO cooperate to recruit and activate WAVE to trigger bacterial invasion. Cell Host Microbe 11, 129-139.
-
(2012)
Cell Host Microbe
, vol.11
, pp. 129-139
-
-
Humphreys, D.1
Davidson, A.2
Hume, P.J.3
Koronakis, V.4
-
17
-
-
66149104554
-
The WAVE regulatory complex is inhibited
-
Ismail, A. M., Padrick, S. B., Chen, B., Umetani, J. and Rosen, M. K. (2009). The WAVE regulatory complex is inhibited. Nat. Struct. Mol. Biol. 16, 561-563.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 561-563
-
-
Ismail, A.M.1
Padrick, S.B.2
Chen, B.3
Umetani, J.4
Rosen, M.K.5
-
18
-
-
0242361514
-
A functional genomic analysis of cell morphology using RNA interference
-
Kiger, A. A., Baum, B., Jones, S., Jones, M. R., Coulson, A., Echeverri, C. and Perrimon, N. (2003). A functional genomic analysis of cell morphology using RNA interference. J. Biol. 2, 27.
-
(2003)
J. Biol.
, vol.2
, pp. 27
-
-
Kiger, A.A.1
Baum, B.2
Jones, S.3
Jones, M.R.4
Coulson, A.5
Echeverri, C.6
Perrimon, N.7
-
19
-
-
80052300765
-
WAVE regulatory complex activation by cooperating GTPases Arf and Rac1
-
Koronakis, V., Hume, P. J., Humphreys, D., Liu, T., Hørning, O., Jensen, O. N. and McGhie, E. J. (2011). WAVE regulatory complex activation by cooperating GTPases Arf and Rac1. Proc. Natl. Acad. Sci. USA 108, 14449-14454.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 14449-14454
-
-
Koronakis, V.1
Hume, P.J.2
Humphreys, D.3
Liu, T.4
Hørning, O.5
Jensen, O.N.6
McGhie, E.J.7
-
20
-
-
0242286595
-
Abi, Sra1, and Kette control the stability and localization of SCAR/WAVE to regulate the formation of actin-based protrusions
-
Kunda, P., Craig, G., Dominguez, V. and Baum, B. (2003). Abi, Sra1, and Kette control the stability and localization of SCAR/WAVE to regulate the formation of actin-based protrusions. Curr. Biol. 13, 1867-1875.
-
(2003)
Curr. Biol.
, vol.13
, pp. 1867-1875
-
-
Kunda, P.1
Craig, G.2
Dominguez, V.3
Baum, B.4
-
21
-
-
77955993031
-
Tao-1 is a negative regulator of microtubule plus-end growth
-
Liu, T., Rohn, J. L., Picone, R., Kunda, P. and Baum, B. (2010). Tao-1 is a negative regulator of microtubule plus-end growth. J. Cell Sci. 123, 2708-2716.
-
(2010)
J. Cell Sci.
, vol.123
, pp. 2708-2716
-
-
Liu, T.1
Rohn, J.L.2
Picone, R.3
Kunda, P.4
Baum, B.5
-
22
-
-
0032403083
-
WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac
-
Miki, H., Suetsugu, S. and Takenawa, T. (1998). WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac. EMBO J. 17, 6932-6941.
-
(1998)
EMBO J
, vol.17
, pp. 6932-6941
-
-
Miki, H.1
Suetsugu, S.2
Takenawa, T.3
-
23
-
-
0348047597
-
Crystal structure of ARF1*Sec7 complexed with Brefeldin A and its implications for the guanine nucleotide exchange mechanism
-
Mossessova, E., Corpina, R. A. and Goldberg, J. (2003). Crystal structure of ARF1*Sec7 complexed with Brefeldin A and its implications for the guanine nucleotide exchange mechanism. Mol. Cell 12, 1403-1411.
-
(2003)
Mol. Cell
, vol.12
, pp. 1403-1411
-
-
Mossessova, E.1
Corpina, R.A.2
Goldberg, J.3
-
24
-
-
41149162021
-
Regulation of actin cytoskeleton dynamics by Arf-family GTPases
-
Myers, K. R. and Casanova, J. E. (2008). Regulation of actin cytoskeleton dynamics by Arf-family GTPases. Trends Cell Biol. 18, 184-192.
-
(2008)
Trends Cell Biol
, vol.18
, pp. 184-192
-
-
Myers, K.R.1
Casanova, J.E.2
-
25
-
-
79959677602
-
Life at the leading edge
-
Ridley, A. J. (2011). Life at the leading edge. Cell 145, 1012-1022.
-
(2011)
Cell
, vol.145
, pp. 1012-1022
-
-
Ridley, A.J.1
-
26
-
-
0141433278
-
Molecular requirements for actin-based lamella formation in Drosophila S2 cells
-
Rogers, S. L., Wiedemann, U., Stuurman, N. and Vale, R. D. (2003). Molecular requirements for actin-based lamella formation in Drosophila S2 cells. J. Cell Biol. 162, 1079-1088.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 1079-1088
-
-
Rogers, S.L.1
Wiedemann, U.2
Stuurman, N.3
Vale, R.D.4
-
27
-
-
80052609464
-
Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype
-
Rohn, J. L., Sims, D., Liu, T., Fedorova, M., Schöck, F., Dopie, J., Vartiainen, M. K., Kiger, A. A., Perrimon, N. and Baum, B. (2011). Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype. J. Cell Biol. 194, 789-805.
-
(2011)
J. Cell Biol.
, vol.194
, pp. 789-805
-
-
Rohn, J.L.1
Sims, D.2
Liu, T.3
Fedorova, M.4
Schöck, F.5
Dopie, J.6
Vartiainen, M.K.7
Kiger, A.A.8
Perrimon, N.9
Baum, B.10
-
28
-
-
79952781379
-
Kinetic studies of the Arf activator Arno on model membranes in the presence of Arf effectors suggest control by a positive feedback loop
-
Stalder, D., Barelli, H., Gautier, R., Macia, E., Jackson, C. L. and Antonny, B. (2011). Kinetic studies of the Arf activator Arno on model membranes in the presence of Arf effectors suggest control by a positive feedback loop. J. Biol. Chem. 286, 3873-3883.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 3873-3883
-
-
Stalder, D.1
Barelli, H.2
Gautier, R.3
Macia, E.4
Jackson, C.L.5
Antonny, B.6
-
29
-
-
26244448510
-
Isoform-selective effects of the depletion of ADP-ribosylation factors 1-5 on membrane traffic
-
Volpicelli-Daley, L. A., Li, Y., Zhang, C. J. and Kahn, R. A. (2005). Isoform-selective effects of the depletion of ADP-ribosylation factors 1-5 on membrane traffic. Mol. Biol. Cell 16, 4495-4508.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 4495-4508
-
-
Volpicelli-Daley, L.A.1
Li, Y.2
Zhang, C.J.3
Kahn, R.A.4
-
30
-
-
70350367835
-
Collective cell migration in development
-
Weijer, C. J. (2009). Collective cell migration in development. J. Cell Sci. 122, 3215-3223.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 3215-3223
-
-
Weijer, C.J.1
-
31
-
-
34548703094
-
An actin-based wave generator organizes cell motility
-
Weiner, O. D., Marganski, W. A., Wu, L. F., Altschuler, S. J. and Kirschner, M. W. (2007). An actin-based wave generator organizes cell motility. PLoS Biol. 5, e221.
-
(2007)
PLoS Biol
, vol.5
-
-
Weiner, O.D.1
Marganski, W.A.2
Wu, L.F.3
Altschuler, S.J.4
Kirschner, M.W.5
-
32
-
-
0037128210
-
SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila
-
Zallen, J. A., Cohen, Y., Hudson, A. M., Cooley, L., Wieschaus, E. and Schejter, E. D. (2002). SCAR is a primary regulator of Arp2/3-dependent morphological events in Drosophila. J. Cell Biol. 156, 689-701.
-
(2002)
J. Cell Biol.
, vol.156
, pp. 689-701
-
-
Zallen, J.A.1
Cohen, Y.2
Hudson, A.M.3
Cooley, L.4
Wieschaus, E.5
Schejter, E.D.6
|