Simalikalactone E (SkE), a new weapon in the armamentarium of drugs targeting cancers that exhibit constitutive activation of the ERK pathway

Oncotarget

Volumn 3, Issue 12, 2012, Pages 1688-1699

  Robert, Guillaume ^a,b,c,d   Jullian, Valérie ^f,g   Jacquel, Arnaud ^a,b,c,d   Ginet, Clémence ^a,b,c,d   Dufies, Maeva ^a,b,c,d   Torino, Stephanie ^a,d,e   Pottier, Anaïs ^a,d,h   Peyrade, Frederic ⁱ   Tartare Deckert, Sophie ^a,d,h   Bourdy, Geneviéve ^f,g   Deharo, Eric ^f,g   Auberger, Patrick ^a,b,c,d  

^a CENTRE MÉDITERRANÉEN DE MÉDECINE MOLÉCULAIRE C3M   (France)

^b Equipe 2 Morts Cellulaires   (France)

^c Equipe labellisée par la Ligue Nationale Contre le Cancer 2011 2013   (France)

^d UNIVERSITÉ CÔTE D'AZUR   (France)

^e Equipe 6 Toxines microbiennes dans la relation hòte pathogénes   (France)

^f CNRS   (France)

^g UMR 152 IRD Universite Paul Sabatier   (France)

^h Equipe 11 Microenvironnement Signalisation et Cancer   (France)

ⁱ CENTRE ANTOINE LACASSAGNE   (France)

Author keywords

B Raf inhibitor; CML; ERK pathway; Hairy Cell Leukemia; Melanoma; Simalikalactone E

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; B RAF KINASE; DABRAFENIB; IMATINIB; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; N [3 (5 CHLORO 1H PYRROLO[2,3 B]PYRIDINE 3 CARBONYL) 2,4 DIFLUOROPHENYL]PROPANESULFONAMIDE; QUASSINOID DERIVATIVE; SIMALIKALACTONE E; UNCLASSIFIED DRUG; VEMURAFENIB;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER INHIBITION; CANCER RESISTANCE; CELL STRAIN K 562; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HAIRY CELL LEUKEMIA; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LEUKEMIA CELL; MELANOMA CELL; MOUSE; NONHUMAN; PROTEIN PHOSPHORYLATION; TUMOR CELL; TUMOR REGRESSION; TUMOR XENOGRAFT;

EID: 84874737968     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.791     Document Type: Article

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