Most influenza A virions fail to express at least one essential viral protein

Journal of Virology

Volumn 87, Issue 6, 2013, Pages 3155-3162

  Brooke, Christopher B ^a   Ince, William L ^a   Wrammert, Jens ^b   Ahmed, Rafi ^b   Wilson, Patrick C ^c   Bennink, Jack R ^a   Yewdell, Jonathan W ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL TYPE; FEMALE; FRACTIONATION; INFLUENZA; INFLUENZA VIRUS A; MDCK CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRION; VIROGENESIS; VIRUS INFECTIVITY; VIRUS STRAIN;

ANIMALS; CELL LINE; DEFECTIVE VIRUSES; DOGS; GENE EXPRESSION REGULATION, VIRAL; GENES, ESSENTIAL; INFLUENZA A VIRUS; VIRAL PROTEINS; VIRION;

EID: 84874702494     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02284-12     Document Type: Article

References (32)

1. Molinari NA, Ortega-Sanchez IR, Messonnier ML, Thompson WW, Wortley PM, Weintraub E, Bridges CB. 2007. The annual impact of seasonal influenza in the US: measuring disease burden and costs. Vaccine 25:5086-5096.
2. Palese P, Shaw ML. 2007. Orthomyxoviridae: the viruses and their replication, p 1647-1689. In Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SE (ed), Fields virology, 5th ed. Lippincott Williams & Wilkins, Philadelphia, PA.
3. Medina RA, Garcia-Sastre A. 2011. Influenza A viruses: new research developments. Nat. Rev. Microbiol. 9:590-603.
4. Wright PF, Neumann G, Kawaoka Y. 2007. Orthomyxoviruses, p 1691-1740. In Knipe DM, Howley PM, Griffin DE, Lamb RA, Martin MA, Roizman B, Straus SE (ed), Fields virology, 5th ed. Lippincott Williams & Wilkins, Philadelphia, PA.
5. Yen HL, Webster RG. 2009. Pandemic influenza as a current threat. Curr. Top. Microbiol. Immunol. 333:3-24.
6. Chou YY, Vafabakhsh R, Doganay S, Gao Q, Ha T, Palese P. 2012. One influenza virus particle packages eight unique viral RNAs as shown by FISH analysis. Proc. Natl. Acad. Sci. U. S. A. 109:9101-9106.
7. Hutchinson EC, von Kirchbach JC, Gog JR, Digard P. 2010. Genome packaging in influenza A virus. J. Gen. Virol. 91:313-328.
8. Martin K, Helenius A. 1991. Nuclear transport of influenza virus ribonucleoproteins: the viral matrix protein (M1) promotes export and inhibits import. Cell 67:117-130.
9. Akkina RK, Chambers TM, Nayak DP. 1984. Expression of defectiveinterfering influenza virus-specific transcripts and polypeptides in infected cells. J. Virol. 51:395-403.
10. Baum A, Sachidanandam R, Garcia-Sastre A. 2010. Preference of RIG-I for short viralRNAmolecules in infected cells revealed by next-generation sequencing. Proc. Natl. Acad. Sci. U. S. A. 107:16303-16308.
11. Von Magnus P. 1954. Incomplete forms of influenza virus. Adv. Virus Res. 2:59-79.
12. Chen W, Calvo PA, Malide D, Gibbs J, Schubert U, Bacik I, Basta S, O'Neill R, Schickli J, Palese P, Henklein P, Bennink JR, Yewdell JW. 2001. A novel influenza A virus mitochondrial protein that induces cell death. Nat. Med. 7:1306-1312.
13. Hale BG, Randall RE, Ortin J, Jackson D. 2008. The multifunctional NS1 protein of influenza A viruses. J. Gen. Virol. 89:2359-2376.
14. Honda A, Ueda K, Nagata K, Ishihama A. 1988. RNA polymerase of influenza virus: role of NP in RNA chain elongation. J. Biochem. 104: 1021-1026.
15. Huang TS, Palese P, Krystal M. 1990. Determination of influenza virus proteins required for genome replication. J. Virol. 64:5669-5673.
16. Hutchinson EC, Curran MD, Read EK, Gog JR, Digard P. 2008. Mutational analysis of cis-acting RNA signals in segment 7 of influenza A virus. J. Virol. 82:11869-11879.
17. Marsh GA, Hatami R, Palese P. 2007. Specific residues of the influenza A virus hemagglutinin viral RNA are important for efficient packaging into budding virions. J. Virol. 81:9727-9736.
18. Marsh GA, Rabadan R, Levine AJ, Palese P. 2008. Highly conserved regions of influenza a virus polymerase gene segments are critical for efficient viral RNA packaging. J. Virol. 82:2295-2304.
19. Muramoto Y, Takada A, Fujii K, Noda T, Iwatsuki-Horimoto K, Watanabe S, Horimoto T, Kida H, Kawaoka Y. 2006. Hierarchy among viral RNA(vRNA) segments in their role in vRNA incorporation into influenza A virions. J. Virol. 80:2318-2325.
20. Desmyter J, Melnick JL, Rawls WE. 1968. Defectiveness of interferon production and of rubella virus interference in a line of African green monkey kidney cells (Vero). J. Virol. 2:955-961.
21. Emeny JM, Morgan MJ. 1979. Regulation of the interferon system: evidence that Vero cells have a genetic defect in interferon production. J. Gen. Virol. 43:247-252.
22. Ngunjiri JM, Sekellick MJ, Marcus PI. 2008. Clonogenic assay of type a influenza viruses reveals noninfectious cell-killing (apoptosis-inducing) particles. J. Virol. 82:2673-2680.
23. Davis AR, Hiti AL, Nayak DP. 1980. Influenza defective interfering viral RNAis formed by internal deletion of genomic RNA. Proc. Natl. Acad. Sci. U. S. A. 77:215-219.
24. Davis AR, Nayak DP. 1979. Sequence relationships among defective interfering influenza viral RNAs. Proc. Natl. Acad. Sci. U. S. A. 76:3092-3096.
25. Nobusawa E, Sato K. 2006. Comparison of the mutation rates of human influenza A and B viruses. J. Virol. 80:3675-3678.
26. Lakadamyali M, Rust MJ, Babcock HP, Zhuang X. 2003. Visualizing infection of individual influenza viruses. Proc. Natl. Acad. Sci. U. S. A. 100:9280-9285.
27. Martin K, Helenius A. 1991. Transport of incoming influenza virus nucleocapsids into the nucleus. J. Virol. 65:232-244.
28. Marklund JK, Ye Q, Dong J, Tao YJ, Krug RM. 2012. Sequence in the influenza A virus nucleoprotein required for viral polymerase binding and RNA synthesis. J. Virol. 86:7292-7297.
29. Noton SL, Simpson-Holley M, Medcalf E, Wise HM, Hutchinson EC, McCauley JW, Digard P. 2009. Studies of an influenza A virus temperature- sensitive mutant identify a late role for NP in the formation of infectious virions. J. Virol. 83:562-571.
30. Hirst GK, Pons MW. 1973. Mechanism of influenza recombination. II. Virus aggregation and its effect on plaque formation by so-called noninfective virus. Virology 56:620-631.
31. Noda T, Sagara H, Yen A, Takada A, Kida H, Cheng RH, Kawaoka Y. 2006. Architecture of ribonucleoprotein complexes in influenza A virus particles. Nature 439:490-492.
32. Noda T, Sugita Y, Aoyama K, Hirase A, Kawakami E, Miyazawa A, Sagara H, Kawaoka Y. 2012. Three-dimensional analysis of ribonucleoprotein complexes in influenza A virus. Nat. Commun. 3:639. doi:10.1038 /ncomms1647.